High Dilutions of a Drug of Covid-19 Origin Show Difference in Ranks

High dilutions (HDs) of drugs, used in Homeopathy, are prepared in aqueous EtOH (ethanol) through serial dilution accompanying mechanical agitation or succussion, and are called potencies. The potencies from the rank 12 onwards are too dilute to contain any original drug molecules. Do the potency ranks show any difference from each other? Do serial dilution and succussion contribute to the difference in potency ranks? This study aims to address these two questions. The throat swab of a Covid-19 patient was preserved and diluted with aqueous EtOH 90% to prepare the mother tincture (MT) and five different potencies of Covid named Covidinum. These potencies and their solvent media were analysed by electronic and vibrational spectroscopy. Charge transfer (CT) and proton transfer interactions occur during preparation of the potencies. The FT-IR spectra of all the test samples after normalization show difference from each other with respect to O-H stretching and bending (v2) bands. Serial dilution and succussion contribute to the observed difference in ranks and CT interactions.

To Assess the Parental Perception on Sleep Habit among the Children in Pediatric Ward and OPD of Jubilee Mission Medical College and Research Institute, Thrissur

Children are the worlds precious resources and the best hope for future. During clinical experiences, observation and rapport with mothers, investigators assess many children show difference in sleep patterns and irritated with daily life. The present study was aimed to assess the parental perception on sleep habit of children in the paediatric ward. Objectives: assess the parental perception on sleep habit among children and to find relationship between sleep habit and selected socio demographic variables. Methodology: Quantitative experimental approach was used with descriptive design. The data were collected from 50 children by using random sampling technique. Data were analysed using descriptive and inferential statistics. Result and interpretation: The findings of the study had shown that majority of subjects 24(48%) of the children belongs to age group of 2 to 3 years, 27(54%) were females, 25(50) of children were moderately nourished.39(78%) of children has a meal pattern of more than one hour before sleep, 60% like outdoor play, 35(70%) does not need toys for sleep. Majority of the parents 22(44%) belongs to 26-30 age group, 25(50%) belongs to females, 17(34%) were graduates, 40(80%) were healthy. we found that there is a relationship between clinical data variables such as nutritional status(p=0.041) with sleep habit of children. By using parental perception questionnaire, we found that parents have good perception on sleep habit among children as out of 50 samples 35(70%) secure good score, 14 (28%) secure satisfactory score and only 1(2%) secure poor score.

Driving Duration Difference in Road Freight Transport Between Vehicles Up to and Over 3.5 Tonnes

Working conditions for drivers in the European Union and Slovakia are governed by European and National regulations. Regulations lay down rules on driving times, breaks and rest periods for drivers of lorries and buses to improve working conditions and road safety. There is no doubt that with increasing freight performance, the number of carriers and vehicles in the field of road freight transport is also increasing. Therefore, in connection with the current EU legislation, which aims to increase road safety, attention is paid to adopting regulations for all road haulage operators and carriers. The purpose of this paper is to show difference between road freight transport performed by vehicles up to 3,5 tonnes and vehicles transporting goods where the maximum permissible mass of the vehicle, including any trailer, or semi-trailer, exceeds 3,5 tonnes.

New species of the genus Adonis L. (Ranunculaceae) from Sakhalin Island

A description of a new species of the genus Adonis, Adonis sachalinensis Gorovoi et S. Volkova, related to A. amurensis Regel et Radde is given. The karyotypes and the morphology characters show difference between plants from Sakhalin Island and Primorye Territory.

Does the orientation of syndesmosis fixative device affect the immediate reduction of the distal tibiofibular joint?

Introduction Incongruent stabilization of the distal tibiofibular joint (syndesmosis) results in poorer long-term outcome in malleolar fractures. The aim was to analyze whether the orientation of the syndesmotic stabilization would affect the immediate reduction imaged in computed tomography (CT). Materials and methods The syndesmotic congruity in 114 ankle fractures with stabilization of the syndesmosis were retrospectively analyzed in the post-operative bilateral CT scans. The incisura device angle (IDA) was defined and correlated with the side-to-side difference of Leporjärvi clear-space (ΔLCS), anterior tibiofibular distance (ΔantTFD) and Nault talar dome angle (ΔNTDA) regardless of the stabilization technique and separately for suture button system and syndesmotic screw. Asymmetric reduction was defined as ΔLCS > 2 mm and |ΔantTFD|> 2 mm. Results Regardless of the stabilization technique, no correlation between the IDA and the ΔLCS (r = 0.069), the ΔantTFD (r = 0.019) nor the ΔNTDA (r = 0.177) could be observed. There were no differences between suture button system and syndesmotic screw. Asymmetrical reduction was detected in 46% of the cases, while sagittal asymmetry was most common. No association was found between the orientation of stabilization device and occurrence of asymmetrical reduction (p > 0.05). The results of suture button system and syndesmotic screw were comparable in this respect (p > 0.05). Conclusion Poor correlation between the orientation of the stabilization device and the immediate post-operative congruity of the syndesmosis could be shown. In contrast to current literature, this study did not show difference of suture button system over syndesmotic screw in this regard. Careful adjustment of the fibula in anteroposterior orientation should be given special attention.

Comparative study of GA and MAC Anesthesia Methods Effects on Oocyte Retrieval in Patients Under IVF Programs

Background: Anesthesia is widely used to manage pain and anxiety during oocyte retrieval in vitro fertilization (IVF), but there is probable interference with the results and success rate of IVF. Objectives: The present study compares the effects of general anesthesia (GA) and monitored anesthesia care (MAC) applied in oocyte retrieval. Methods: The general anesthesia used in this study comprised a fentanyl-propofol mixture to reach hypnotic concentrations. Intravenous ketamine-midazolam were used for MAC before procedures according to prescribed doses. In sum, 180 women were recruited for research while 90 women selected for general and 90 for MAC methods. Results: The collected oocytes were higher in number in general group (11.25 ± 4.39) than MAC group (7.03 ± 3.84, P < 0.001), meanwhile, the analyses did not show difference between groups regarding the number of fertilized oocytes (4.52 ± 3.18 vs. 4.15 ± 3.02). The differences in successful pregnancy was not significant. Conclusions: Thus, it seems from findings that fentanyl-propofol GA without nitrous oxide is an appropriate alternative to ketamine-midazolam MAC and can be used for IVF oocyte retrieval if GA is demanded.

Testing leptoquark/EFT in $${\bar{B}} \rightarrow {D^{(*)}}l{\bar{\nu }}$$ at the LHC

We investigate the current LHC bounds on New Physics (NP) that contributes to $${\bar{B}} \rightarrow {D^{(*)}}l{\bar{\nu }}$$ B ¯ → D ( ∗ ) l ν ¯ for $$l = (e,\mu ,\tau )$$ l = ( e , μ , τ ) by considering both leptoquark (LQ) models and an effective-field-theory (EFT) Hamiltonian. Experimental analyses from $$l+\text {missing}$$ l + missing searches with high $$p_T$$ p T are applied to evaluate the NP constraints with respect to the Wilson coefficients. A novel point of this work is to show difference between LQs and EFT for the applicable LHC bound. In particular, we find that the EFT description is not valid to search for LQs with the mass less than $$\lesssim 10\,\text {TeV}$$ ≲ 10 TeV at the LHC and leads to overestimated bounds. We also discuss future prospects of high luminosity LHC searches including the charge asymmetry of background and signal events. Finally, a combined summary for the flavor and LHC bounds is given, and then we see that in several NP scenarios the LHC constraints are comparable with the flavor ones.

Comparison of Key Characteristics of Remarkable SSW Events in the Southern and Northern Hemisphere

&lt;p&gt;An exceptionally strong sudden stratospheric warming (SSW) in the Southern Hemisphere (SH) during September 2019 was observed. Because SSW in the SH is very rare, comparison with the only recorded major SH SSW is done. According to World Meteorological Organization (WMO) definition, the SSW in 2019 has to be classified as minor. The cause of SSW in 2002 was very strong activity of stationary planetary wave with zonal wave-number (ZW) 2, which reached its maximum when the polar vortex split into two circulations with polar temperature enhancement by 30 K/week and it penetrated deeply to the lower stratosphere and upper troposphere. On the other hand, the minor SSW in 2019 involved an exceptionally strong wave-1 planetary wave and a large polar temperature enhancement by 50.8 K/week, but it affected mainly the middle and upper stratosphere. The strongest SSW in the Northern Hemisphere was observed in 2009. This study provides comparison of two strongest SSW in the SH and the strongest SSW in the NH to show difference between two hemispheres and possible impact to the lower or higher layers.&lt;/p&gt;

Peripheral intravenous cannulae in neonates: To splint or not?

Objective: To determine the effect of splint on the dwell time of peripheral intravenous cannula in neonates. Setting: Level II Neonatal Intensive Care Unit (NICU). Patients: Consecutive babies with presumed need of peripheral intravenous access of at least 24 h. Methods: Enrolled subjects were randomized to “splint” or “splint-less” group. Insertion site was cleaned with Isopropyl alcohol and 2% Chlorhexidine and peripheral intravenous catheter was inserted under strict asepsis. Insertion sites was examined regularly for occurrence of complication which necessitated removal of the catheter. Results: Out of 159 neonates, 80 were allotted to splint group and the rest to splint-less group. Mean dwell time of intravenous line in splint group was 27.68 ± 13.03 h which was significantly less than in splint-less group (32.87 ± 15.79 h, mean difference: 5.11 h, p value: 0.03). Subgroup analysis in preterms showed mean dwell time of 28.54 ± 14.86 h in splint group which was less than that of splint-less group (35.10 ± 16.24 h) ( p value: 0.03). No such difference was noted in the term neonates. Subgroup analysis for catheters put across joints does not show difference in mean dwell times between splint and splint-less groups. Multivariate regression analysis did not identify any variable which independently affected the outcome. Conclusion: Use of splint does not prolong the dwell time of the catheter and is probably harmful in some neonates.

Kinematic Analysis of 2-Point and 3-Point Jump Shot of Elite Young Male and Female Basketball Players

Basketball shooting is one of the most important offensive skills in basketball. Winning or losing a game mostly depends on the shooting effectiveness. The study aims to compare the selected kinematic variables of 2-point (2-pt) and 3-point (3-pt) jump shots (after making a cut and receiving the ball) and ascertain the differences between elite male under 16 and 18 (U16M, U18M) and female under 16 and 18 (U16F, U18F) basketball players. Overall, forty-eight young male and female basketball players participated in the study. 3D motion analysis using an inertial suit with the addition of utilizing a smart ball was performed for assessing the 2-pt and 3-pt shooting techniques. Players in male categories shot for 2-pt with a higher center of mass difference in the vertical direction (U16M 5.7 cm, U18M 3.9 cm vs. U16F 1.4 cm, U18F 0.6 cm), with higher release shoulder angle (U16M 110.9, U18M 113.8 vs. U16F 103, U18F 105), and with a higher entry angle of the ball (U16M 34, U18M 32 vs. U16F 30, U18F 30) when compared to female categories (p < 0.001). In the 3-pt shooting, there were differences between male and female categories in the shoulder angle when releasing the ball (p < 0.001). In the players shooting speed, there were differences between U16M vs. U18F (0.95 ± 0.1 vs. 0.88 ± 0.1; p = 0.03) and U16F vs. U18F (0.96 ± 0.06 vs. 0.88 ± 0.1; p = 0.02) players. Male categories shot 3-pt shots with a smaller center of mass difference in the horizontal direction when compared to 2-pt shots (p < 0.001). The entry angle was higher in successful shooting attempts compared to unsuccessful shooting attempts when shooting for 3-pt (p = 0.02). Player shooting speed was higher in all categories (except U18F) when shooting for 3-pt (p < 0.001). It appears that performers show difference in kinematic variables based on distance from the basket. Basketball coaches and players should work to minimize the kinematic differences between 2-pt and 3-pt shooting and to optimize the shooting technique.