scholarly journals Detection of metal ions in biological systems: A review

2020 ◽  
Vol 39 (1) ◽  
pp. 231-246 ◽  
Author(s):  
Xian Zheng ◽  
Wenyu Cheng ◽  
Chendong Ji ◽  
Jin Zhang ◽  
Meizhen Yin
Keyword(s):  
Metal Ions ◽  
Metal Ion ◽  
Metabolic Regulation ◽  
Organic Dyes ◽  
Biological Systems ◽  
High Sensitivity ◽  
Transportation Energy ◽  
Material Transportation ◽  
High Fluorescence ◽  
Metal Ion Detection

Abstract Metal ions are widely present in biological systems and participate in many critical biochemical processes such as material transportation, energy conversion, information transmission and metabolic regulation, making them indispensable substance in our body. They can cause health problems when deficiency or excess occurs. To understand various metabolic processes and facilitate diseases diagnosis, it is very important to measure the content and monitor the distribution of metal ions in individual cells, tissues and whole organisms. Among the various methods for metal ion detection, fluorescent sensors with organic dyes have attracted tremendous attention due to many advantages such as high fluorescence quantum yield, facile modification approaches and biocompatibility in addition to operation ease, high sensitivity, fast detection speed, and real-time detection. This review summarizes the recent progress on the detection and imaging of the metal ions in biological systems including Na+, K+, Ca2+, Mg2+, Fe2+/Fe3+, Zn2+, and Cu2+ provides an opinion on remaining challenges to be addressed in this field.

Synthesis of multifunctional poly(1-pyrenemethyl methacrylate)-b-poly(N-isopropylacrylamide)-b-poly(N-methylolacrylamide)s and their electrospun nanofibers for metal ion sensory applications

2015 ◽  
Vol 6 (12) ◽  
pp. 2327-2336 ◽  
Author(s):  
Jau-Tzeng Wang ◽  
Yu-Cheng Chiu ◽  
Han-Sheng Sun ◽  
Kohei Yoshida ◽  
Yougen Chen ◽  
...  
Keyword(s):  
Metal Ions ◽  
Temperature Variation ◽  
Metal Ion ◽  
Triblock Copolymers ◽  
Electrospun Nanofibers ◽  
High Sensitivity

PPy-b-PNIPAAm-b-PNMA multifunctional triblock copolymers based electrospun nanofibers detected temperature variation or metal-ions with a high sensitivity.

Highly Fluorescent N-Doped Carbon Quantum Dots Derived from Bamboo Stems for Selective Detection of Fe3+ Ions in Biological Systems

2021 ◽  
Vol 17 (2) ◽  
pp. 312-321
Author(s):  
Jiamin Yan ◽  
Yuneng Lu ◽  
Shaowen Xie ◽  
Haihu Tan ◽  
Weilan Tan ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Biological Systems ◽  
High Sensitivity ◽  
Carbon Quantum Dots ◽  
Clinical Diagnostics ◽  
Quenching Effect ◽  
Biologically Relevant ◽  
Sensing Platform ◽  
Wide Ph Range ◽  
High Fluorescence

The establishment of sensing platform for trace analysis of Fe3+ in biological systems is meaningful for health monitoring. Herein, a Fe3+ sensitive fluorescent nanoprobe was constructed based on highly fluorescent N-doped carbon quantum dots (NCQDs) derived from bamboo stems through a hydrothermal method employing ethylenediamine as the nitrogen dopant. The prepared NCQDs had a uniformly distributed size and their mean size was around 2.43 nm. Abundant functional groups (C=N, N-H, C=O, and carboxyl) anchored on NCQDs demonstrated successful doping of N in CQDs. The obtained NCQDs possessed a high fluorescence quantum yield of 20.02% and outstanding fluorescence stability over a wide pH range and at high ionic strengths. Moreover, Fe3+ ions presented a specific fluorescent quenching effect to the as-prepared NCQDs. The calibration curve for fluorescence quenching degree corresponding to Fe3+ concentration showed a linear response in a range of 0.01–10 µM, and detection limit was 0.486 µM, which indicated that the NCQDs had high sensitivity to Fe3+ ions. Ascribed to these unique properties, the NCQDs were selected as luminescent probes for trace amount of Fe3+ ions in human serum. These results demonstrated their promising use in clinical diagnostics and other biologically relevant studies.

Pentafluorophenyl dipyrrin as probe for transition metal ion detection and bioremediation in Bacillus subtilis and Bacillus cereus

2017 ◽  
Vol 41 (19) ◽  
pp. 11190-11200 ◽  
Author(s):  
Dijo Prasannan ◽  
Chellaiah Arunkumar
Keyword(s):  
Bacillus Subtilis ◽  
Transition Metal ◽  
Metal Ions ◽  
Bacillus Cereus ◽  
Metal Ion ◽  
Transition Metal Ions ◽  
Ion Detection ◽  
Transition Metal Ion ◽  
Metal Ion Detection

Recognition of transition metal ions and bioaccumulation in B. subtilis and B. cereus were examined using pentafluorophenyl dipyrrin probe.

19F CEST imaging probes for metal ion detection

2017 ◽  
Vol 15 (30) ◽  
pp. 6441-6446 ◽  
Author(s):  
Qiaoli Peng ◽  
Yaping Yuan ◽  
Huaibin Zhang ◽  
Shaowei Bo ◽  
Yu Li ◽  
...  
Keyword(s):  
Metal Ions ◽  
Metal Ion ◽  
Ion Detection ◽  
Cest Imaging ◽  
Highly Sensitive ◽  
Imaging Probes ◽  
Metal Ion Detection

An easily available fluorinated chelator was developed as a highly sensitive 19F iCEST MRI probe for selectively detecting metal ions.

Extended dipyrrin ligands: candidates for optical metal ion detection under competitive conditions

2017 ◽  
Vol 53 (22) ◽  
pp. 3213-3215 ◽  
Author(s):  
S. Guski ◽  
M. Albrecht ◽  
T. Willms ◽  
M. Albrecht ◽  
T. Nabeshima ◽  
...  
Keyword(s):  
Metal Ions ◽  
Metal Ion ◽  
Ion Detection ◽  
Metal Ion Detection

Extended acyl hydrazine based dipyrrine ligands lead to a specific colour response upon addition of metal ions.

Unraveling the highly selective nature of silver-based metal–organic complexes for the detection of metal ions: the synergistic effect of dicarboxylic acid linkers

2020 ◽  
Vol 8 (15) ◽  
pp. 5051-5057 ◽  
Author(s):  
Chi Van Nguyen ◽  
Babasaheb M. Matsagar ◽  
Tansir Ahamad ◽  
Saad M. Alshehri ◽  
Wei-Hung Chiang ◽  
...  
Keyword(s):  
Synergistic Effect ◽  
Metal Ions ◽  
Dicarboxylic Acid ◽  
Metal Ion ◽  
Ion Detection ◽  
Organic Complexes ◽  
Metal Organic ◽  
Metal Ion Detection

The effect of dicarboxylic acid linkers of Ag-PLMOCs for highly selective metal ion detection.

scholarly journals Development of Biopolymer and Conducting Polymer-Based Optical Sensors for Heavy Metal Ion Detection

Molecules ◽  
2020 ◽  
Vol 25 (11) ◽  
pp. 2548 ◽  
Author(s):  
Nur Syahira Md Ramdzan ◽  
Yap Wing Fen ◽  
Nur Ain Asyiqin Anas ◽  
Nur Alia Sheh Omar ◽  
Silvan Saleviter
Keyword(s):  
Heavy Metal ◽  
Metal Ions ◽  
Conducting Polymer ◽  
Metal Ion ◽  
Heavy Metal Ions ◽  
Polymer Materials ◽  
Heavy Metal Ion ◽  
Sufficient Evidence ◽  
Ion Detection ◽  
Metal Ion Detection

Great efforts have been devoted to the invention of environmental sensors as the amount of water pollution has increased in recent decades. Chitosan, cellulose and nanocrystalline cellulose are examples of biopolymers that have been intensively studied due to their potential applications, particularly as sensors. Furthermore, the rapid use of conducting polymer materials as a sensing layer in environmental monitoring has also been developed. Thus, the incorporation of biopolymer and conducting polymer materials with various methods has shown promising potential with sensitively and selectively toward heavy metal ions. In this feature paper, selected recent and updated investigations are reviewed on biopolymer and conducting polymer-based materials in sensors aimed at the detection of heavy metal ions by optical methods. This review intends to provide sufficient evidence of the potential of polymer-based materials as sensing layers, and future outlooks are considered in developing surface plasmon resonance as an excellent and valid sensor for heavy metal ion detection.

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