Der Nutzen der Mesoökonomie für ökonomische Paradigmenbildung am Beispiel der Agrarökonomie

2012 ◽  
Vol 63 (3) ◽  
Author(s):  
Stefan Mann
Keyword(s):  
Nobel Prize ◽  
Economic History ◽  
Special Section ◽  
Welfare Economics ◽  
Agricultural Economics ◽  
Added Value ◽  
Economic Science ◽  
Empirical Analyses

SummaryIn order to check the potentials of mesoeconomic research, the example of agricultural economics serves as a case in point to look for advances which contributed to progress in general economic science. In the literature of economic history, the pioneer work by J. H. v. Thünen catches the eye, while T. W. Schultz is a classic Agricultural Economist who won the Nobel Prize. A special section is devoted to mathematical progress within Agricultural Economics and the role of agricultural economists in welfare economics. It is concluded that a high added value can be generated through restricting empirical analyses to a particular sector.

scholarly journals Dove va la storia economica? Metodi e prospettive. Secc. XIII-XVIII – Where is Economic History Going? Methods and Prospects from the 13th to the 18th Centuries

2011 ◽  
Keyword(s):  
Social Sciences ◽  
Economic History ◽  
General Context ◽  
Economic Science ◽  
Current State ◽  
Industrial Age ◽  
History Of ◽  
The Many ◽  
Over Time

The book proposes to take stock of the situation of the studies of economic history of the pre-industrial age, in an attempt to grasp what – in the current state of European research – is the cultural scope and role of the discipline among the many specialisations of history and economic science. It analyses the different approaches that have characterised the various European historiography schools over time, as well as the evolution and prospects of directions of research; it reflects on the analysis of the sources, the methods that are at the basis of their use, and the interpretative questions that they pose for the academic. Finally it proposes the inclusion of economic history within the more general context of research, through an interdisciplinary comparison between the method proper to this discipline and that of other economic and social sciences.

A “New” Business History? A Commentary on the 1993 Nobel Prize in Economics

1993 ◽  
Vol 67 (4) ◽  
pp. 623-636 ◽  
Author(s):  
William N. Parker
Keyword(s):  
Nobel Prize ◽  
Economic History ◽  
Business History ◽  
Economic Science ◽  
Human Element ◽  
Main Charge ◽  
New Business ◽  
Prize Award ◽  
The University ◽  
Washington University

The editor of the Business History Review has asked me, as the oldest “new” economic historian, to make a comment on the 1993 Nobel Prize award in Economics—a comment directed to “real” historians—which I am not—and especially to business historians, of whose product I have been an often satisfied—though occasionally restless—consumer. Needless to say, I find this to be an assignment difficult to fulfill. Praise will be put down to “trendy” insincerity and criticism to jealousy. Nor will Historians miss the irony in all the excitement generated by the award within a sub-tribe whose main charge has been to minimize the biographical, the “human” element in historical explanation. The self-styled “new” economic history movement, christened half-jokingly as early as 1968 by an ingenious neologism, “Cliometrics,” was now, twenty-five years later, awarded what is formally known as the Bank of Sweden Prize in Economic Science in Honor of Alfred Nobel, in the persons of two of its very keen and most prolific, best-known, energetic, and indomitable practitioners, Douglass C. North of Washington University (St. Louis, Mo.) and Robert W. Fogel of the University of Chicago (Chicago, Ill.). Surely there is some lesson in marketing in all this to make business and entrepreneurial historians sit up and take notice.

scholarly journals Dissecting the contribution of O-Antigen and proteins to the immunogenicity of Shigella sonnei generalized modules for membrane antigens (GMMA)

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Francesca Mancini ◽  
Gianmarco Gasperini ◽  
Omar Rossi ◽  
Maria Grazia Aruta ◽  
Maria Michelina Raso ◽  
...  
Keyword(s):  
Protective Immunity ◽  
Critical Role ◽  
Shigella Sonnei ◽  
Added Value ◽  
Protein Antigens ◽  
Outer Membranes ◽  
O Antigen ◽  
Membrane Antigens ◽  
Specific Igg

AbstractGMMA are exosomes released from engineered Gram-negative bacteria resembling the composition of outer membranes. We applied the GMMA technology for the development of an O-Antigen (OAg) based vaccine against Shigella sonnei, the most epidemiologically relevant cause of shigellosis. S. sonnei OAg has been identified as a key antigen for protective immunity, and GMMA are able to induce anti-OAg-specific IgG response in animal models and healthy adults. The contribution of protein-specific antibodies induced upon vaccination with GMMA has never been fully elucidated. Anti-protein antibodies are induced in mice upon immunization with either OAg-negative and OAg-positive GMMA. Here we demonstrated that OAg chains shield the bacteria from anti-protein antibody binding and therefore anti-OAg antibodies were the main drivers of bactericidal activity against OAg-positive bacteria. Interestingly, antibodies that are not targeting the OAg are functional against OAg-negative bacteria. The immunodominant protein antigens were identified by proteomic analysis. Our study confirms a critical role of the OAg on the immune response induced by S. sonnei GMMA. However, little is known about OAg length and density regulation during infection and, therefore, protein exposure. Hence, the presence of protein antigens on S. sonnei GMMA represents an added value for GMMA vaccines compared to other OAg-based formulations.

scholarly journals Assessing social preferences in reimbursement negotiations for new Pharmaceuticals in Oncology: an experimental design to analyse willingness to pay and willingness to accept

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Dominik J. Wettstein ◽  
Stefan Boes
Keyword(s):  
Willingness To Pay ◽  
Real World ◽  
Cognitive Biases ◽  
Social Preferences ◽  
Standard Of Care ◽  
Added Value ◽  
Amazon Mechanical Turk ◽  
Patient Organisation ◽  
Patient Benefit

Abstract Background Price negotiations for specialty pharmaceuticals take place in a complex market setting. The determination of the added value of new treatments and the related societal willingness to pay are of increasing importance in policy reform debates. From a behavioural economics perspective, potential cognitive biases and other-regarding concerns affecting outcomes of reimbursement negotiations are of interest. An experimental setting to investigate social preferences in reimbursement negotiations for novel, oncology pharmaceuticals was used. Of interest were differences in social preferences caused by incremental changes of the patient outcome. Methods An online experiment was conducted in two separate runs (n = 202, n = 404) on the Amazon Mechanical Turk (MTurk) platform. Populations were split into two (run one) and four (run two) equally sized treatment groups for hypothetical reimbursement decisions. Participants were randomly assigned to the role of a public price regulator for pharmaceuticals (buyer) or a representative of a pharmaceutical company (seller). In run two, role groups were further split into two different price magnitude framings (“real world” vs unconverted “real payoff” prices). Decisions had real monetary effects on other participants (in the role of premium payers or investors) and via charitable donations to a patient organisation (patient benefit). Results 56 (run one) and 59 (run two) percent of participants stated strictly monotone preferences for incremental patient benefit. The mean incremental cost-effectiveness ratio (ICER) against standard of care (SoC) was higher than the initial ICER of the SoC against no care. Regulators stated lower reservation prices in the “real world” prices group compared to their colleagues in the unconverted payoff group. No price group showed any reluctance to trade. Overall, regulators rated the relevance of the patient for their decision higher and the relevance of their own role lower compared to sellers. Conclusions The price magnitude of current oncology treatments affects stated preferences for incremental survival, and assigned responsibilities lead to different opinions on the relevance of affected stakeholders. The design is useful to further assess effects of reimbursement negotiations on societal outcomes like affordability (cost) or availability (access) of new pharmaceuticals and test behavioural policy interventions.

Science Diplomacy in the Twentieth Century: Introduction

2021 ◽  
pp. 002200942110067
Author(s):  
Soenke Kunkel
Keyword(s):  
Twentieth Century ◽  
Foreign Policy ◽  
Foreign Relations ◽  
Special Section ◽  
Contemporary History ◽  
Global Environmental Problems ◽  
Global Environmental ◽  
Science Diplomacy ◽  
The Cold War

Setting the stage for the special forum, this introduction points to the centrality of science diplomacy activities within many current foreign policy concepts around the world. It also points to the lack of historical perspective within many current academic debates about science diplomacy. Suggesting the value of such a perspective, the introduction then draws attention to a number of fruitful contributions that histories of science diplomacy may make to contemporary history. These include: a better understanding of how entanglements between science, foreign policy, and international relations evolved over the twentieth century; a refined understanding of the workings of foreign relations and diplomacy that sheds light on the role of science as an arena of foreign relations; new insights into the Cold War; a globalizing of perspectives in the writing of contemporary history; a new international focus on widely under-researched actors like universities, science movements, science organizations, and science academies; a focus on new themes that range from global environmental problems to issues like cultural heritage. The remainder of the introduction then delineates some of the shared assumptions and findings of the essays and then briefly introduces each contribution to the special section.

Family and non-family sources of knowledge diversity in family firms: The role of causation logics

2020 ◽  
pp. 026624262095335
Author(s):  
Robert V Randolph ◽  
Hanqing ‘Chevy’ Fang ◽  
Esra Memili ◽  
Dilek Zamantili Nayir
Keyword(s):  
Family Firms ◽  
Knowledge Capital ◽  
Knowledge Resources ◽  
Knowledge Diversity ◽  
Sources Of Knowledge ◽  
Formal Causation ◽  
Intra Family ◽  
Empirical Analyses

This article will critically analyse the sources and the role of knowledge diversity in informing causation logics in family firms. Family firms rely on knowledge resources from both intra-family and extra-family sources, which may require different approaches to effectively manage. We argue that as family firms acquire greater knowledge diversity, family-centred effectuation processes become limited and they will increasingly rely on formal causation logics to coordinate these resources. However, we expect this relationship to differ when knowledge diversity is sourced from either family or non-family sources. Empirical analyses of 242 small- and medium-sized family firms indicate that knowledge diversity positively affects a firm’s reliance on causation logics, regardless of the source of that diversity. This suggests that the affinity of family firms to leverage effectuation logics may not be characteristic of family firms in general, but instead may be an artefact of firm reliance on knowledge capital concentrated in family owners.

scholarly journals “Our Victims Define Our Borders”: Commemorating Yugoslav Partisans in the Italo-Yugoslav Borderland

2017 ◽  
Vol 31 (2) ◽  
pp. 290-310
Author(s):  
Borut Klabjan
Keyword(s):  
World War Ii ◽  
Cultural Landscape ◽  
Special Section ◽  
Iron Curtain ◽  
World War ◽  
Production Of Space ◽  
National Narratives ◽  
Local Newspaper ◽  
Grassroots Initiatives

This article is part of the special section titled From the Iron Curtain to the Schengen Area, guest edited by Wolfgang Mueller and Libora Oates-Indruchová. This article discusses local cultures of remembrance of Yugoslav partisans fallen during World War II in Trieste, now part of Italy, and investigates the role of memory activists in managing vernacular memory over time. The author analyses the interplay between memory and the production of space, something which has been neglected in other studies of memory formation. On the basis of local newspaper articles, archival material, and oral interviews, the essay examines the ideological imprint on the local cultural landscape, contributing to a more complex understanding of memory engagement. The focus is on grassroots initiatives rather than state-sponsored heritage projects. This article argues that memory initiatives are not solely the outcome of national narratives and top–down ideological impositions. It shows that official narratives have to negotiate with vernacular forms of memory engagement in the production of a local mnemonic landscape.

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