Äquivalenzprinzip und Finanzpolitik: Ein Besteuerungsprinzip (erneut) auf dem Prüfstand

1997 ◽  
Vol 46 (3) ◽  
Author(s):  
Bernd Hansjürgens

AbstractThe article analyses the potential role of the benefit principle in public finance. Against the background that the benefit principle plays a minor part both in the theory and in the politics of public finance, first the advantages of this principle are traced out. By bringing together both sides of the budget the benefit principle leads to a stronger cost-benefit orientation in the citizen’s preferences and serves as an instrument to curb Leviathan. Given these advantages the arguments against the application of the benefit principle are critically (re)analysed and potential fields of a stronger application are developed. The analysis ends with the design of elements of a “constitutional pact” in order to strengthen the role of the benefit principle in public policy.

Author(s):  
Katherine Guérard ◽  
Sébastien Tremblay

In serial memory for spatial information, some studies showed that recall performance suffers when the distance between successive locations increases relatively to the size of the display in which they are presented (the path length effect; e.g., Parmentier et al., 2005) but not when distance is increased by enlarging the size of the display (e.g., Smyth & Scholey, 1994). In the present study, we examined the effect of varying the absolute and relative distance between to-be-remembered items on memory for spatial information. We manipulated path length using small (15″) and large (64″) screens within the same design. In two experiments, we showed that distance was disruptive mainly when it is varied relatively to a fixed reference frame, though increasing the size of the display also had a small deleterious effect on recall. The insertion of a retention interval did not influence these effects, suggesting that rehearsal plays a minor role in mediating the effects of distance on serial spatial memory. We discuss the potential role of perceptual organization in light of the pattern of results.


Author(s):  
Lidiya Derbenyova

The article explores the role of antropoetonyms in the reader’s “horizon of expectation” formation. As a kind of “text in the text”, antropoetonyms are concentrating a large amount of information on a minor part of the text, reflecting the main theme of the work. As a “text” this class of poetonyms performs a number of functions: transmission and storage of information, generation of new meanings, the function of “cultural memory”, which explains the readers’ “horizon of expectations”. In analyzing the context of the literary work we should consider the function of antropoetonyms in vertical context (the link between artistic and other texts, and the groundwork system of culture), as well as in the context of the horizontal one (times’ connection realized in the communication chain from the word to the text; the author’s intention). In this aspect, the role of antropoetonyms in the structure of the literary text is extremely significant because antropoetonyms convey an associative nature, generating a complex mechanism of allusions. It’s an open fact that they always transmit information about the preceding text and suggest a double decoding. On the one hand, the recipient decodes this information, on the other – accepts this as a sort of hidden, “secret” sense.


Author(s):  
Margarita Díaz-Andreu ◽  
Marie Louise Stig Sørensen

Gender archaeology has by now become a relatively well-established research topic within archaeology. Recent years have seen the publication of a number of edited volumes, a rapidly expanding number of papers, and even a few journals and newsletters dedicated to this subject. It is, therefore, very surprising that in this literature the historiographic analysis of women archaeologists has played only a minor part. Likewise they are hardly acknowledged in the ‘folk’ histories of the discipline (Lucy and Hill 1994: 2). The need to understand the disciplinary integration of women, to appreciate the varying socio-political contexts of their work, to reveal the unique tension between their roles as women and their academic lives, has become obvious and is strongly felt in many areas of the discipline. The insights yielded by such analysis will have significance at many levels and will be of paramount importance for the intellectual history of archaeology. In particular, such insights will necessitate a much-needed revision of disciplinary history by revealing its mechanisms of selecting and forgetting, and will play an important role in the analysis of archaeology’s knowledge claims. Histories of archaeology have broadly accepted, and spread, a perception of archaeology as being male-centred, both intellectually and in practice. These accounts, written by male archaeologists such as Glyn Daniel (1975), Alain Schnapp (1993), and Bruce Trigger (1989), are inevitably androcentric in their conceptualization and reconstruction of the disciplinary past. Their versions have, however, recently begun to be contested, as concern with critical historiography has grown, and a few explicit historiographical accounts of women archaeologists have appeared. So far, with regard to the role of women, the most extensive contributions are the edited volumes by Claassen (1994) and du Cros and Smith (1993). While providing an important beginning, these publications show that there is still a long way to go. In particular they demonstrate a gap in research coverage, as no investigation of the contribution of women outside the USA and Australia exists.


2017 ◽  
Vol 14 (4) ◽  
pp. 224
Author(s):  
Adam J. Roper ◽  
Peter Leverett ◽  
Timothy D. Murphy ◽  
Peter A. Williams

Environmental contextThe dispersion of antimony in the environment has been misunderstood over the last few decades. Investigating the solubility of naturally forming mineral phases such as nadorite resulted in determination of its limited role in Sb dispersion, providing evidence that nadorite can only limit antimony dispersion in mildly oxidising conditions. Nadorite can only play a significant role in Sb immobilisation in a particular redox window, which forms only a minor part of the framework of Sb dispersion. AbstractAs part of a study of the control that secondary minerals exert on the dispersion of antimony and bismuth in the supergene environment, syntheses and stability studies of nadorite (PbSbO2Cl) and perite (PbBiO2Cl) have been undertaken. Solubilities in aqueous HNO3 were determined at 298.2K and the data obtained used to calculate values of ΔGfθ(298.2K). The ΔGfθ(s, 298.2K) values for PbSbO2Cl (–622.0±2.8kJmol–1) and PbBiO2Cl (–590.0±1.3kJmol–1) have been used in subsequent calculations to determine relative stabilities and relationships with other common secondary Sb and Bi minerals. While the role of nadorite in immobilising Sb is dependent upon the prevailing redox potential such that SbIII is stable, perite may be a significant phase in limiting the dispersion of Bi in certain supergene settings.


2017 ◽  
Vol 10 (2) ◽  
pp. 219-263 ◽  
Author(s):  
Katja Hannß
Keyword(s):  

In this present paper, the etymological composition of Kallawaya, a mixed and secret language of Bolivia, will be discussed. I will argue that the lexicon of Kallawaya is more heterogeneous than has been assumed so far. In particular, the role of the allegedly main lexifier language Pukina will be critically re-assessed and I will suggest that only a minor part of the Kallawaya lexicon can be related to Pukina. The issues of secrecy and intentional borrowing will also be addressed.


2015 ◽  
Vol 112 (32) ◽  
pp. E4458-E4464 ◽  
Author(s):  
Amin Omairi-Nasser ◽  
Vicente Mariscal ◽  
Jotham R. Austin ◽  
Robert Haselkorn

The filamentous nitrogen-fixing cyanobacteriumAnabaenasp. PCC 7120 differentiates specialized cells, heterocysts, that fix atmospheric nitrogen and transfer the fixed nitrogen to adjacent vegetative cells. Reciprocally, vegetative cells transfer fixed carbon to heterocysts. Several routes have been described for metabolite exchange within the filament, one of which involves communicating channels that penetrate the septum between adjacent cells. Severalfragene mutants were isolated 25 y ago on the basis of their phenotypes: inability to fix nitrogen and fragmentation of filaments upon transfer from N+ to N− media. Cryopreservation combined with electron tomography were used to investigate the role of threefragene products in channel formation. FraC and FraG are clearly involved in channel formation, whereas FraD has a minor part. Additionally, FraG was located close to the cytoplasmic membrane and in the heterocyst neck, using immunogold labeling with antibody raised to the N-terminal domain of the FraG protein.


2014 ◽  
Vol 32 (25) ◽  
pp. 2727-2734 ◽  
Author(s):  
Gudrun Schleiermacher ◽  
Niloufar Javanmardi ◽  
Virginie Bernard ◽  
Quentin Leroy ◽  
Julie Cappo ◽  
...  

Purpose In neuroblastoma, the ALK receptor tyrosine kinase is activated by point mutations. We investigated the potential role of ALK mutations in neuroblastoma clonal evolution. Methods We analyzed ALK mutations in 54 paired diagnosis–relapse neuroblastoma samples using Sanger sequencing. When an ALK mutation was observed in one paired sample, a minor mutated component in the other sample was searched for by more than 100,000× deep sequencing of the relevant hotspot, with a sensitivity of 0.17%. Results All nine ALK-mutated cases at diagnosis demonstrated the same mutation at relapse, in one case in only one of several relapse nodules. In five additional cases, the mutation seemed to be relapse specific, four of which were investigated by deep sequencing. In two cases, no mutation evidence was observed at diagnosis. In one case, the mutation was present at a subclonal level (0.798%) at diagnosis, whereas in another case, two different mutations resulting in identical amino acid changes were detected, one only at diagnosis and the other only at relapse. Further evidence of clonal evolution of ALK-mutated cells was provided by establishment of a fully ALK-mutated cell line from a primary sample with an ALK-mutated cell population at subclonal level (6.6%). Conclusion In neuroblastoma, subclonal ALK mutations can be present at diagnosis with subsequent clonal expansion at relapse. Given the potential of ALK-targeted therapy, the significant spatiotemporal variation of ALK mutations is of utmost importance, highlighting the potential of deep sequencing for detection of subclonal mutations with a sensitivity 100-fold that of Sanger sequencing and the importance of serial samplings for therapeutic decisions.


2021 ◽  
Author(s):  
Suzanne van Dooremalen ◽  
Anke Janssen ◽  
Lauri Bloemenkamp ◽  
Austin Yonka ◽  
Dennis Beringer ◽  
...  

abT cells engineered to express a defined gdTCR (TEG) to attack cancer cells have shown great promise when using a g9d2TCR to redirect abT cells. Reports by us and recent reports by others support the key role of the g9d2TCR in cancer recognition. We further emphasized the crucial role of the dTCR chain and that differences in CDR3 sequences of the dTCR chain modulates functional avidity of TEGs. We and others demonstrated that also d2 negative gdTCRs are able to redirect abT cells towards different tumor cell lines. However, some studies suggest that d2 negative gdTCRs play a minor role in the tumor recognition by d2 negative gdT cells. In addition for both modes of action for tumor-recognition, d2 negative gdTCR-dependent and -independent, it has been suggested that CMV infection is not only a major driver of d2 negative gdT cell expansion but also induces tumor-cross reactive d2 negative gdT cells. Therefore, we aimed to systematically explore frequencies of tumor reactive d2 negative gdT cells in naive repertoires (cord blood) and patients with or without CMV infection and examined the potential role the parental d2 negative gdTCR in anti-tumor reactivity of selected clones. We observed that approximately 30% of all tested clones were tumor-reactive, though no differences were observed between different sources. Surprisingly, none of the so far tested gdTCR did mediate strong anti-tumor reactivity of the parental clones. Though numbers of tested TCR sequences are still low, our data imply that tumor-reactivity of d2 negative gdT cells is frequently not mediated by the d2 negative gdTCR alone.


1971 ◽  
Vol 35 (3) ◽  
pp. 40-46 ◽  
Author(s):  
Donald E. Sexton

The difference in food prices to blacks and to whites is one source of urban unrest. The author surveys the answers to the question, “Do blacks pay more?” An effort is made to show what is known and where further research is needed. This article is an example of the potential role of marketing research in public policy.


2019 ◽  
Vol 2 (1) ◽  
pp. 589-599
Author(s):  
Hamed Alavi ◽  
Shano Ibrahim Ghafour

Abstract The purpose of this paper is to identify the main challenges faced by entrepreneurs in the Kurdistan region of Iraq and possible ways that regional public sector can take for the purpose of improving entrepreneurship development. Given the importance of entrepreneurs in the economic development and job creation, it’s critical to understand what drives entrepreneurs to become less effective and to investigate how the implementation of “entrepreneurship ecosystem” practiced by public policy makers mitigates these challenges. As a result, authors strive to answers two main questions in this paper: “What are the factors that hold back entrepreneurs in the Kurdistan Region to start their own businesses? “And “What measures the local government can take to mitigate such challenges?” The methodology used in this study is quantitative approach, involving a survey questionnaire. This paper consists of four parts: After the introduction, second part will provide empirical data on challenges facing entrepreneurs in Kurdistan Region of Iraq. Discussion and analysis of the findings are done in the third part. Finally, in the last part, paper will offer conclusions by summarizing the key findings.


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