scholarly journals Cobalt Oxide Nanoparticles/Graphene/Ionic Liquid CrystalModified Carbon Paste Electrochemical Sensor for Ultra-sensitiveDetermination of a Narcotic Drug

2019 ◽  
Vol 9 (1) ◽  
pp. 110-121 ◽  
Author(s):  
Nada Farouk Atta ◽  
Ahmed Galal ◽  
Ekram Hamdy El-Ads ◽  
Samar Hamed Hassan
Keyword(s):  
Ionic Liquid ◽  
Electrochemical Sensor ◽  
Cobalt Oxide ◽  
Dynamic Range ◽  
Electrochemical Impedance ◽  
Oxide Nanoparticles ◽  
Carbon Paste ◽  
Great Ability ◽  
Cobalt Oxide Nanoparticles

Purpose: Drug-abuse, namely morphine (MO) affects the metabolism of neurotransmitterssuch as dopamine (DA). Therefore, it is crucial to devise a sensitive sensing technique tosimultaneously determine both compounds in real samples.Methods: The fabrication of the sensor is based on in situ modification of a carbon paste (CP)electrode with cobalt oxide nanoparticles, graphene, and ionic liquid crystal in presence ofsodium dodecyl sulfate; CoGILCCP-SDS. The modified sensor is characterized using scanningelectron microscopy, electrochemical impedance spectroscopy and voltammetry measurements.Results: Electron transfer kinetics and analytical performance of the proposed sensor wereenhanced due to the synergistic role of all the modifiers. The simultaneous determination of MOand DA achieved low detection limits of 0.54 nmol L−1 and 0.25 nmol L−1, respectively. Besides,a carbon-based electrochemical sensor is fabricated for the nano-molar determination of MOin real samples and formulations. The sensor showed fouling resistance and anti-interferenceability in presence of other species in human fluids. The real sample analysis of MO wassuccessfully achieved with good recovery results in urine samples and pharmaceutical tablets.Linear dynamic range, sensitivity, detection limit and quantification limit of MO in urine were5 nmol L−1 to 0.6 μmol L−1, 6.19 μA/μmol L-1, 0.484 nmol L−1 and 1.61 nmol L−1, respectively.Conclusion: This sensor has great ability to be extended for electrochemical applications inassaying of many drugs.

Electrochemical sensor based on incorporation of gold nanoparticles, ionic liquid crystal, and β-cyclodextrin into carbon paste composite for ultra-sensitive determination of norepinephrine in real samples

2019 ◽  
Vol 97 (12) ◽  
pp. 805-814
Author(s):  
Nada F. Atta ◽  
Ahmed Galal ◽  
Dalia M. El-Said
Keyword(s):  
Gold Nanoparticles ◽  
Ionic Liquid ◽  
Liquid Crystal ◽  
Electrochemical Sensor ◽  
Current Response ◽  
Carbon Paste ◽  
Great Ability ◽  
Real Samples ◽  
Sensitive Determination

A novel, reliable electrochemical sensor is fabricated for direct and sensitive determination of norepinephrine (NE) based on gold nanoparticles, ionic liquid crystal, and β-cyclodextrin modified carbon paste electrode, namely AuILCCDCPE. The ionic liquid crystal (ILC) played a key role in improving the current response of electro-oxidation of NE compared with other ionic liquids modified electrodes. The ILC increased the ionic conductivity of the paste and formed noncovalent interactions with both host (CD) and guest (NE) compounds. The solid state structure of the ILC helped in the formation of ordered films in the paste. Furthermore, CD and Au nanoparticles raised the stability and the electrocatalytic ability of the proposed sensor. Under optimized conditions, the fabricated electrochemical sensor showed a good electrochemical response towards NE in human urine in the linear dynamic ranges of 0.05–10 μmol/L and 20–300 μmol/L with a correlation coefficient of 0.999 and detection limit of 3.12 × 10−9 mol/L in the low concentration range. The practical analytical performance of the sensor was attained for determination of NE in real samples with satisfied recovery results. This sensor has great ability to be extended for electrochemical applications in assays of other drugs.

scholarly journals A new electrochemical sensor based on carbon paste electrode/Ru(III) complex for determination of nitrite: Electrochemical impedance and cyclic voltammetry measurements

Measurement ◽  
2016 ◽  
Vol 92 ◽  
pp. 524-533 ◽  
Author(s):  
Achour Terbouche ◽  
Siham Lameche ◽  
Chafia Ait-Ramdane-Terbouche ◽  
Djamila Guerniche ◽  
Djahida Lerari ◽  
...  
Keyword(s):  
Cyclic Voltammetry ◽  
Electrochemical Sensor ◽  
Carbon Paste Electrode ◽  
Electrochemical Impedance ◽  
Carbon Paste ◽  
Paste Electrode

Electrochemical Behavior and Voltammetric Determination of Losartan Using Carbon Ceramic Electrode Modified with Room Temperature Ionic Liquid

2020 ◽  
Vol 18 (4) ◽  
pp. 322-327
Author(s):  
Mahzad Firouzi ◽  
Masoud Giahi ◽  
Mostafa Najafi ◽  
Seyed Saied Homami ◽  
Seyed Husain Hashemi Mousavi
Keyword(s):  
Ionic Liquid ◽  
Room Temperature ◽  
Dynamic Range ◽  
Electrochemical Impedance ◽  
Linear Sweep Voltammetry ◽  
Pharmaceutical Formulations ◽  
Room Temperature Ionic Liquid ◽  
Carbon Ceramic Electrode ◽  
Carbon Ceramic

Herein, an electrochemical sensor has been proposed for the determination of losartan (LOS) in pharmaceutical formulations. A room temperature ionic liquid, 1-butyl-3-methylimidazolium hexafluorophosphate (BMIM.PF6) was applied to fabricate a modified carbon ceramic electrode (IL-CCE). The electrochemical studies were performed by the cyclic and linear sweep voltammetry (CV and LSV), chronoamperometry and electrochemical impedance spectroscopy (EIS) techniques. The anodic peak currents were increased with the LOS concentration and indicated a linear dynamic range from 20 to 200 μM and a detection limit of 11.7 μM (S/N = 3) under the optimized conditions. Satisfactory results were obtained by analysis of LOS in pharmaceutical tablets.

Highly sensitive electrochemical sensor based on pyrrolidinium ionic liquid modified ordered mesoporous carbon paste electrode for determination of carbendazim

2015 ◽  
Vol 7 (4) ◽  
pp. 1493-1498 ◽  
Author(s):  
Yu Ya ◽  
Tianshun Wang ◽  
Liping Xie ◽  
Junjie Zhu ◽  
Li Tang ◽  
...  
Keyword(s):  
Ionic Liquid ◽  
Electrochemical Sensor ◽  
Mesoporous Carbon ◽  
Carbon Composite ◽  
Ordered Mesoporous Carbon ◽  
Carbon Paste ◽  
Ordered Mesoporous ◽  
Liquid Ordered ◽  
Pyrrolidinium Ionic Liquid

A novel electrochemical sensor based on pyrrolidinium ionic liquid-ordered mesoporous carbon composite system for the determination of carbendazim was developed.

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