Pneumocephalus is a rare consequence of epidural anesthesia, which may occur following
inadvertent or unidentified dural puncture when the loss of resistance to air technique is
applied to identify the epidural space. Headache is the most common symptom presented
in this condition, usually with sudden onset. This case report describes an unusual
presentation of diffuse pneumocephalus after an unidentified dural puncture. The patient
(male, 67 years old) was submitted to epidural catheter placement for the treatment of
acute exacerbation of ischemic chronic pain using loss of resistance to air technique. No
cerebrospinal fluid or blood flashback was observed after needle withdrawal. Shortly after
the intervention, the patient presented symptoms of lethargy, apathy, and hypophonia,
which are not commonly associated with pneumocephalus. No motor or sensory deficits
were detected. Cranial computed tomography showed air in the frontal horn of the left
ventricle, subarachnoid space at interhemispheric fissure and basal cisterns, confirming
the diagnosis of diffuse pneumocephalus. The patient remained under vigilance with
oxygen therapy and the epidural catheter left in place. After 24 hours, cranial computed
tomography showed air in the temporal and frontal horns of the left ventricle, with no air
in the subarachnoid space. The patient presented no neurological signs or symptoms at
this time. Although headache is the most common symptom presented in reported cases
of pneumocephalus, this case shows the need for the clinician to be aware of other signs
and symptoms that may be indicative of this condition, in order to properly diagnose and
treat these patients.
Key words: Pneumocephalus, continuous epidural analgesia, ischemic chronic pain, lossof-resistance to air technique, dural puncture, headache, unusual presentation