Rent to Own; or, What's Entailed in Pride and Prejudice

2003 ◽  
Vol 82 (1) ◽  
pp. 1-23 ◽  
Author(s):  
Sandra Macpherson
Keyword(s):  
Literary History ◽  
Legal History ◽  
Pride And Prejudice ◽  
Model Form ◽  
Social Obligation ◽  
History Of ◽  
Short And Long Term

This essay attempts to explain the function of the most famous entail in literary history. The essay begins with a brief survey of the legal history of entailment, focusing in particular on the contradictory notions of agency and obligation embedded in the English fee. The author argues that Austen is familiar with this history and these contradictions, and that in Pride and Prejudice, the entail - which had seemed a threat to social obligation - becomes a model form of sociability. What is entailed in Pride and Prejudice, she concludes, is an argument about short- and long-term obligations: an argument on behalf of a model of obligation whose durability and impersonality is enabled by the technology - at once conceptual and historical - of entailment.

Infective endocarditis in patients who use IV drugs: a single centre cohort

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
H Alraddadi ◽  
A Alsagheir ◽  
S Gao ◽  
K An ◽  
H Hronyecz ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Infective Endocarditis ◽  
Long Term Outcomes ◽  
Replacement Surgery ◽  
Short Term Mortality ◽  
History Of ◽  
Short And Long Term ◽  
Baseline Characteristics

Abstract Background Managing endocarditis in intravenous drug use (IVDU) patients is challenging: unless patients successfully quit IVDU, the risk of re-infection is high. Clinicians often raise concerns with ethical and resource allocation principles when considering valve replacement surgery in this patient population. To help inform practice, we sought to determine the long-term outcomes of IVDU patients with endocarditis who underwent valve surgery in our center. Method After research ethics board approval, infective endocarditis cases managed surgically at our General Hospital between 2009 and 2018 were identified through the Cardiac Care Network. We reviewed patients' charts and included those with a history of IVDU in this study. We abstracted data on baseline characteristics, peri-operative course, short- and long-term outcomes. We report results using descriptive statistics. Results We identified 124 IVDU patients with surgically managed endocarditis. Mean age was 37 years (SD 11), 61% were females and 8% had redo surgery. During admission, 45% (n=56) of the patients had an embolic event: 63% pulmonary, 30% cerebral, 18% peripheral and 11% mesenteric. Causative organisms included Methicillin-Sensitive Staphylococcus Aureus (51%, n=63), Methicillin-Resistant Staphylococcus Aureus (15%, n=19), Streptococcus Viridans (2%, n=2), and others (31%, n=38). Emergency cardiac surgery was performed for 42% of patients (n=52). Most patients (84%) had single valve intervention: 53% tricuspid, 18% aortic and 13% mitral. Double valve interventions occurred in 15% (n=18). Overall, bioprosthetic replacement was most commonly chosen (79%, n=98). In-hospital mortality was 7% (n=8). Median length of stay in hospital was 13 days (IQR 8,21) and ICU 2 days (IQR 1,6). Mortality at longest available follow-up was 24% (n=30), with a median follow-up of 129 days (IQR 15,416). Valve reintervention rate was 11% (n=13) and readmission rate was 14% (n=17) at a median of 275 days (IQR 54,502). Conclusion Despite their critical condition, IVDU patients with endocarditis have good intra-hospital outcomes. Challenges occur after hospital discharge with loss of follow-up and high short-term mortality. IVDU relapse likely accounts for some of these issues. In-hospital and community comprehensive addiction management may improve these patients' outcomes beyond the surgical procedure. Annual rate 2009–2018 Funding Acknowledgement Type of funding source: None

Abstract P101: Short and Long-Term Outcomes in Aspirin Treated PCI Patients Using NSAIDs

2011 ◽  
Vol 4 (suppl_1) ◽  
Author(s):  
Rizwan Alimohammad ◽  
Sayed Tariq ◽  
Ali Elkharbotly ◽  
Ed Timm ◽  
Mikhail Torosoff
Keyword(s):  
Myocardial Infarction ◽  
Rank Test ◽  
Long Term Outcomes ◽  
Chi Square ◽  
Low Dose Aspirin ◽  
History Of ◽  
Short And Long Term ◽  
Mortality Table ◽  
Prolonged Hospital

Background: NSAIDs may exert direct deleterious effects on CV system, while non-selective (NS) -NSAIDs may also diminish cardio-protective effect of low-dose aspirin. On another hand, NSAIDs may decrease CRP levels and ameliorate systemic inflammation. We have investigated short and long-term outcomes associated with NSAIDs use in post-PCI patients. Methods and Material: NSAID utilization, hospital and long-term outcomes of 2933 percutaneous coronary revascularizations (PCI) were collected and analyzed. Patients not on aspirin, or treated with rofecoxib and valdecoxib were excluded. ANOVA, Chi-square, Kaplan-Meyer analysis with log-rank test, and logistic regression were utilized. The study was approved by the Institutional IRB. Results: Patients treated with NS-NSAIDs, but not celecoxib, experienced longer length of stay, higher incidence of peri-procedural myocardial infarction, and mildly increased post-PCI mortality (Table). These effects were unchanged after adjustment for age (p=0.001), ejection fraction (p<0.001), and history of previous MI (p<0.001). There was a trend towards lower long-term (50+/-15 months) mortality in NS-NSAIDs (9%) and celecoxib (6.7%) treated patients, when compared to the rest of the cohort (11.3%, Table). Conclusion: Non-selective NSAIDs, but not Celecoxib, are associated with prolonged hospital stay and increased peri-procedural myocardial infarction in PCI patients. Long-term mortality does not appear to be affected by the NSAIDs use at the time of PCI. Randomized studies of this important clinical question are needed.

scholarly journals Longitudinal prediction of falls and near falls frequencies in Parkinson’s disease: a prospective cohort study

2020 ◽  
Author(s):  
Beata Lindholm ◽  
Christina Brogårdh ◽  
Per Odin ◽  
Peter Hagell
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Prospective Cohort ◽  
Prediction Models ◽  
Evidence Base ◽  
History Of ◽  
Short And Long Term ◽  
Near Falls ◽  
Short Time

Abstract Introduction and objective Several prediction models for falls/near falls in Parkinson’s disease (PD) have been proposed. However, longitudinal predictors of frequency of falls/near falls are poorly investigated. Therefore, we aimed to identify short- and long-term predictors of the number of falls/near falls in PD. Methods A prospective cohort of 58 persons with PD was assessed at baseline (mean age and PD duration, 65 and 3.2 years, respectively) and 3.5 years later. Potential predictors were history of falls and near falls, comfortable gait speed, freezing of gate, dyskinesia, retropulsion, tandem gait (TG), pain, and cognition (Mini-Mental State Exam, MMSE). After each assessment, the participants registered a number of falls/near falls during the following 6 months. Multivariate Poisson regression was used to identify short- and long-term predictors of a number of falls/near falls. Results Baseline median (q1–q3) motor (UPDRS) and MMSE scores were 10 (6.75–14) and 28.5 (27–29), respectively. History of falls was the only significant short-time predictor [incidence rate ratio (IRR), 15.17] for the number of falls/near falls during 6 months following baseline. Abnormal TG (IRR, 3.77) and lower MMSE scores (IRR, 1.17) were short-term predictors 3.5 years later. Abnormal TG (IRR, 7.79) and lower MMSE scores (IRR, 1.49) at baseline were long-term predictors of the number of falls/near falls 3.5 years later. Conclusion Abnormal TG and MMSE scores predict the number of falls/near falls in short and long term, and may be indicative of disease progression. Our observations provide important additions to the evidence base for clinical fall prediction in PD.

scholarly journals Atrial fibrillation in a child with COVID-19 infection

2020 ◽  
pp. 1-4
Author(s):  
Aura Daniella Santi ◽  
Paolo Aquino ◽  
Molly Dorfman
Keyword(s):  
Atrial Fibrillation ◽  
Delay In Diagnosis ◽  
History Of ◽  
Short And Long Term ◽  
Onset Atrial Fibrillation ◽  
New Onset

Abstract The SARS-CoV-2 (COVID-19) pandemic has challenged our initial predictions of its ramifications, both short and long term. Cardiovascular manifestations of COVID-19 in children remain a topic of investigation as literature is lacking. We describe new onset atrial fibrillation in a child with a history of COVID-19 infection. Understanding of cardiogenic effects of COVID-19 can help minimise the delay in diagnosis.

scholarly journals Preprints & Pandemics: Interventions into the Dynamic Scholarly System of Scholarly Communication

2021 ◽  
Author(s):  
Micah Altman ◽  
Philip N. Cohen ◽  
Jessica Polka
Keyword(s):  
Public Health ◽  
Science Communication ◽  
Ad Hoc ◽  
Scholarly Communication ◽  
External Shocks ◽  
Scholarly Communications ◽  
History Of ◽  
Short And Long Term ◽  
The Impact

The COVID-19 pandemic is an exemplar of how scholarly communication can change in response to external shocks, even as the scholarly knowledge ecosystem is evolving rapidly, and many argue that swift and fundamental interventions are needed. However, it is much easier to identify ongoing changes and emerging interventions than to understand their immediate and long term impacts. This is illustrated by comparing the approaches applied by the scientific community to understand public health risks and interventions with those applied by the scholarly communications community to the science of COVID-19. There are substantial disagreements over the short- and long- term benefits of most proposed approaches to changing the practice of science communication, and the lack of systematic, empirically-based research in this area makes these controversies difficult to resolve. We argue that the methodology of analysis and intervention developed within public health can be usefully applied to the science-of-science. Starting with the history of DDT application, we illustrate four ways complex human systems threaten reliable predictions and blunt ad-hoc interventions. We then show how these four threats apply lead to the last major intervention in scholarly publication -- the article publishing charge based open access model -- to yield surprising results. Finally, we outline how these four threats may affect the impact of preprint initiatives, and we identify approaches drawn from public health to mitigate these threats.

Introduction

2021 ◽  
pp. 1-34
Author(s):  
Juliane Fürst
Keyword(s):  
Soviet Union ◽  
Oral History ◽  
The Soviet Union ◽  
History Of ◽  
Short And Long Term ◽  
Late Socialism ◽  
Authorial Voice

Hippies in the late Soviet Union appeared to many like creatures from a different star. Yet, a closer look reveals that the history of this movement has both short- and long-term precedents, which range from early revolutionary ideals to the generation of beatniks and Beatles fans, who were only slightly older than the wave of hippie youngsters that appeared in the late 1960s all across the Soviet Union. The introduction also situates the topic of Soviet hippies both within the history of the global hippie movement as well as in the context of late Soviet life and reality. A separate discussion is devoted to the methodology of oral history and the role of the subjective authorial voice. The introduction concludes with the overall argument of the book that the worlds of hippies and late socialism were not incompatible but in a bizarre way a good fit to each other that shaped the character of both.

scholarly journals Real-world evidence on short- and long-term outcomes for acute coronary syndrome patients with a prior history of atrial fibrillation

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
P Gouda ◽  
A Savu ◽  
K Bainey ◽  
R Welsh ◽  
R.K Sandhu
Keyword(s):  
Myocardial Infarction ◽  
Hospital Mortality ◽  
Prior History ◽  
Long Term Outcomes ◽  
St Segment Elevation ◽  
Segment Elevation Myocardial Infarction ◽  
St Segment ◽  
History Of ◽  
Short And Long Term

Abstract Background Acute coronary syndromes (ACS) are often complicated by new-onset atrial fibrillation (AF), which is associated with higher short-term mortality. It is unknown whether a prior history of AF affects outcomes beyond in-hospital mortality in a real-world setting. Purpose To assess (i) the prevalence of prior AF in patients with ACS, including unstable angina (UA), non-ST-segment elevation myocardial infarction (NSTEMI) and ST-segment elevation myocardial infarction (STEMI); (ii) clinical characteristics of ACS patients with and without AF; and (iii) in-hospital mortality and long-term outcomes in the presence of prior AF. Methods We used linked administrative health databases to identify patients hospitalized with a primary diagnosis of ACS and prior history of non-valvular AF (ICD-9 code 427.3 and ICD-10 code 148), which was defined as 1 hospitalization or 1 emergency department visit or 2 outpatient visits at least 30 days apart in 1 year in any position, between April 2002 and March 2016 in Alberta, Canada. Outcomes included in-hospital mortality, long-term mortality and a composite of all-cause mortality, hospitalisation for myocardial infarction (MI) or stroke over 3 years. Kaplan-Meier curves were constructed for mortality and the composite outcome according to presence of prior AF and ACS type. Results Of 31,056 presenting with an ACS, 4,173 (13.4%) had a prior history of AF. Compared to patients without prior AF, patients with AF were older (75.7 versus 64.7 years), female (35.5% versus 29.9%), with a higher comorbidity burden (Charlson Comorbidity Index 1.7 versus 1.1). Patient with AF more often presented with NSTEMI (57.7% versus 48.2%) and UA (17.1% versus 16.4%) compared to STEMI (25.2% versus 35.4%). In-hospital mortality was higher for ACS patients in the presence of prior AF (8.1% versus 3.3%; p&lt;0.0001). Mortality and the composite endpoint were also significantly higher in patients with prior AF compared to those without AF (Panel A and B) over the 3-year period. A worse prognosis was observed for STEMI and NSTEMI patients with prior AF compared to any other group (panel C and D). Conclusion In this large, population-based study, we found that a history of AF is common in patients presenting with an ACS. In the presence of AF, short- and long-term prognosis is poor particularly for STEMI and NSTEMI patients. Aggressive modification of shared risk factors and use of evidence-based therapies to improve outcomes is needed in this high-risk population. Outcomes by presence of AF and ACS type Funding Acknowledgement Type of funding source: None

STUDIES ON CHANGES OF ELEMENTAL CONCENTRATION IN A HUMAN BODY BY MEANS OF ANALYSES OF LONG HAIRS BASED ON THE STANDARD-FREE METHOD

2009 ◽  
Vol 19 (01n02) ◽  
pp. 17-27 ◽  
Author(s):  
K. SERA ◽  
K. TERASAKI ◽  
T. SASAKI ◽  
S. GOTOH ◽  
Y. SAITOH ◽  
...  
Keyword(s):  
Human Body ◽  
Elemental Concentration ◽  
Hair Samples ◽  
Rapid Changes ◽  
Long Term Changes ◽  
History Of ◽  
Short And Long Term ◽  
Women And Children ◽  
Daily Changes

We established and reported two years ago the original methods for evaluating daily changes of elemental concentration in a body by means of a standard-free method for powdered beard samples daily taken with electric shaver. It was found that the method is quite useful for investigating short- and long-term changes of elemental concentration in a body. However, the method for beard analysis is applicable only to men. In order to estimate daily changes of elemental concentration in a body for women and children, a new method which allows us to quantitatively analyze hair samples cut into 1 mm pieces has been developed and applied to three long hair samples taken from three persons. It is found that the method enables us to estimate both long- and short-term changes in elemental concentration in a body as well as beard analysis. It is found that sulfur keeps almost constant over a long period, and arsenic shows very rapid changes with a few days' period, while mercury shows only long-term changes with the period of a few months. These behaviors are almost the same as those observed in beard analyses. On the other hand, bromine shows a certain seasonal changes; its concentration shows a certain trend of increasing in summer and decreasing in winter. Lead and calcium show very long-term changes, and the behavior of strontium is quite similar to that of calcium. The method is expected to give us information about history of changes in elemental concentration in a human body over a few or more years. It is expected that the behavior of arsenic showing rapid elevation within a few days can be explained as a response to intakes of arsenic-rich foods. It is expected that the method gives us a clue to the identification of the main pathways of human exposure to certain toxic elements.

scholarly journals Short and Long-term Survival Rates following Myocardial Infarction and its Predictive Factors: A Study Using National Registry Data

2021 ◽  
Author(s):  
Samaneh Mozaffarian ◽  
Korosh Etemad ◽  
Mohammad Aghaali ◽  
Soheila Khodakarim ◽  
Sahar Sotoodeh Ghorbani ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Heart Disease ◽  
Predictive Factors ◽  
Survival Rates ◽  
Term Survival ◽  
Risk Of Death ◽  
Chronic Heart Disease ◽  
History Of ◽  
Short And Long Term

Background: Coronary artery disease is the most common cause of death worldwide as well as in Iran. The present study was designed to predict short and long-term survival rates after the first episode of myocardial infarction (MI). Methods: The current research is a retrospective cohort study. The data were collected from the Myocardial Infarction Registry of Iran in a 12-month period leading to March 20, 2014. The variables analyzed included smoking status, past medical history of chronic heart disease, hypertension, diabetes, hyperlipidemia, signs and symptoms during an attack, post-MI complications during hospitalization, the occurrence of arrhythmias, the location of MI, and the place of residence. Survival rates and predictive factors were estimated by the Kaplan–Meier method, the log-rank test, and the Cox model. Results: Totally, 21 181 patients with the first MI were studied. There were 15 328 men (72.4%), and the mean age of the study population was 62.10±13.42 years. During a 1-year period following MI, 2479 patients (11.7%) died. Overall, the survival rates at 28 days, 6 months, and 1 year were estimated to be 0.95 (95% CI: 0.95 to 0.96), 0.90 (95% CI: 0.90 to 0.91), and 0.88 (95% CI: 0.88 to 0.89). After the confounding factors were controlled, history of chronic heart disease (p<0.001), hypertension (p<0.001), and diabetes (p<0.001) had a significant relationship with an increased risk of death and history of hyperlipidemia (p<0.001) and inferior wall MI (p<0.001) had a significant relationship with a decreased risk of death. Conclusion: The results of this study provide evidence for health policy-makers and physicians on the link between MI and its predictive factors.

scholarly journals Perceptions and possible solutions for violence against children among mothers of under five

2020 ◽  
Vol 7 (5) ◽  
pp. 1843
Author(s):  
V. Kirthana ◽  
Praveen Kulkarni ◽  
Nayanabai Shabadi ◽  
M. R. Narayana Murthy ◽  
Anil S. Bilimale
Keyword(s):  
Child Abuse ◽  
Family Members ◽  
Global Public Health ◽  
Violence Against Children ◽  
Under Five ◽  
Medical College ◽  
Mental Disturbances ◽  
History Of ◽  
Short And Long Term

Background: Violence has been one of the most complex contemporary phenomena and their manifestations are responsible for social and mental disturbances of children. This phenomenon is a serious problem of global public health, presenting various causes that compromise socio-cultural levels of society. The objective of the study was to assess the perceptions on causes and consequences of violence against children among mothers of under five children and to describe the common solutions for the violence against children as perceived by mothers.Methods: This qualitative research was undertaken in the urban field practice area of Department of Community Medicine, JSS Medical College, Mysore. A total of 20 women were interviewed for free-listing exercise and the data regarding their perception about causes, consequences and methods of prevention of violence on children were collected. The data collected through free listing and pile sorting was analyzed using Visual Anthropac 1.0.Results: Among 20 subjects interviewed, mean age of the women interviewed was 29.6 years, 70% were completed basic schooling, 30% had history of substance abuse by family members. Common themes emerged out were subjects being not aware of child abuse, opined that child abuse was solely from family members, claimed that they do not abuse their children, opted to remain silent in the circumstances of child abuse, believed it hamper child growth.Conclusions: It is necessary to intervene violence as it means to prevent it through short- and long-term goals such as the implementation of public policies, programs that aim at changes capable of modifying the conditions that favour this phenomenon.

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