The state of periodontum and cardiovascular risk factors in adolescents with high blood pressure

Objective — To establish significant associations between periodontium status, circadian blood pressure (BP) profile and cardiovascular risk factors in adolescents with high BP. Material and Methods — The cross-sectional study involved 113 adolescents (78 boys) aged 10 to 17 years, with a BP level (during repeated office measurements) of ≥95 percentile for age, height and sex, or ≥140/90 mmHg in adolescents older than 16 years. All adolescents were subjected to 24-hour blood pressure monitoring, anthropometric measurements, laboratory blood tests (lipids, uric acid, alanine aminotransferase, aspartate aminotransferase, fasting glucose), echocardiography (left ventricular myocardial mass index, relative wall thickness), assessment of the stage of puberty, dental examination (complex periodontal index (CPI), oral hygiene index). The association between the periodontium status and cardiovascular risk factors was assessed using univariant and multiple regression analysis, adjusted by sex, age, Tanner stage, body mass index, and oral hygiene index. Results — Clinical features of periodontitis were found in 32.7% of adolescents. Multiple regression analysis showed the presence of significant associations of CPI with the levels of systolic, mean and pulse BP during 24 hours (β=0.42, р=0.0001; β=0.31, р=0.003 and β=0.26, р=0.018, respectively), diastolic BP in the daytime (β=0.23, р=0.019), as well as the indices of load with high systolic BP within 24 hours (β=0.42, р=0.0001) and diastolic BP in the daytime (β=0.25, р=0.006). None of the other cardiovascular risk factors showed meaningful relationships with periodontium status in the multivariate analysis. Conclusion — The relationship between periodontium status and blood pressure level exists already in adolescence. That may, on the one hand, justify assessment of periodontium status and (if necessary) timely implementation of prophylactic measures in adolescents with high blood pressure and, on the other hand, recommend BP assessment in adolescents with diagnosed periodontitis.

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Haematocrit: Relationships with Blood Lipids, Blood Pressure and other Cardiovascular Risk Factors

Thrombosis and Haemostasis ◽

10.1055/s-0038-1648811 ◽

1994 ◽

Vol 72 (01) ◽

pp. 058-064 ◽

Cited By ~ 14

Author(s):

Goya Wannamethee ◽

A Gerald Shaper

Keyword(s):

Physical Activity ◽

Risk Factors ◽

Blood Pressure ◽

Body Mass Index ◽

Cardiovascular Risk ◽

Cardiovascular Risk Factors ◽

Alcohol Intake ◽

Blood Lipids ◽

The Other ◽

The Relationship

SummaryThe relationship between haematocrit and cardiovascular risk factors, particularly blood pressure and blood lipids, has been examined in detail in a large prospective study of 7735 middle-aged men drawn from general practices in 24 British towns. The analyses are restricted to the 5494 men free of any evidence of ischaemic heart disease at screening.Smoking, body mass index, physical activity, alcohol intake and lung function (FEV1) were factors strongly associated with haematocrit levels independent of each other. Age showed a significant but small independent association with haematocrit. Non-manual workers had slightly higher haematocrit levels than manual workers; this difference increased considerably and became significant after adjustment for the other risk factors. Diabetics showed significantly lower levels of haematocrit than non-diabetics. In the univariate analysis, haematocrit was significantly associated with total serum protein (r = 0*18), cholesterol (r = 0.16), triglyceride (r = 0.15), diastolic blood pressure (r = 0.17) and heart rate (r = 0.14); all at p <0.0001. A weaker but significant association was seen with systolic blood pressure (r = 0.09, p <0.001). These relationships remained significant even after adjustment for age, smoking, body mass index, physical activity, alcohol intake, lung function, presence of diabetes, social class and for each of the other biological variables; the relationship with systolic blood pressure was considerably weakened. No association was seen with blood glucose and HDL-cholesterol. This study has shown significant associations between several lifestyle characteristics and the haematocrit and supports the findings of a significant relationship between the haematocrit and blood lipids and blood pressure. It emphasises the role of the haematocrit in assessing the risk of ischaemic heart disease and stroke in individuals, and the need to take haematocrit levels into account in determining the importance of other cardiovascular risk factors.

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High blood pressure and associated cardiovascular risk factors in France

Journal of Hypertension ◽

10.1097/00004872-200110000-00005 ◽

2001 ◽

Vol 19 (10) ◽

pp. 1727-1732 ◽

Cited By ~ 34

Author(s):

Roland Asmar ◽

Sylviane Vol ◽

Bruno Pannier ◽

Anne-Marie Brisac ◽

Jean Tichet ◽

...

Keyword(s):

Risk Factors ◽

Blood Pressure ◽

Cardiovascular Risk ◽

Cardiovascular Risk Factors ◽

High Blood Pressure

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Role of Duke treadmill score in the diagnosis of ischemic heart disease in women

Romanian Journal Of Internal Medicine ◽

10.1515/rjim-2015-0020 ◽

2015 ◽

Vol 53 (2) ◽

pp. 146-152

Author(s):

Alexandra Dǎdârlat ◽

D. Zdrenghea ◽

Dana Pop

Keyword(s):

Risk Factors ◽

Blood Pressure ◽

Heart Disease ◽

Cardiovascular Risk ◽

Ischemic Heart Disease ◽

Cardiovascular Risk Factors ◽

High Blood Pressure ◽

Ischemic Heart ◽

Risk Category ◽

Duke Treadmill Score

Abstract Ischemic heart disease is underdiagnosed in women due to atypical symptomatology as well as to the lower specificity of several paraclinical tests, such as exercise stress testing. The aim of the study was to ascertain whether the Duke treadmill score (DTS) could be an efficient parameter in the diagnosis of ischemic heart disease in women. Material and method. 105 patients were enrolled in the study, 45.71% women with average age ranged between 20 and 70 years, investigated in the Rehabilitation Hospital, Cardiology-Departament, Cluj-Napoca, Romania. All the patients were clinically assessed as concerns the presence of cardiovascular risk factors, and they underwent electrocardiographic, echocardiographic and treadmill stress tests. DST was calculated according to the formula: exercise time – 5 x (ST deviation expressed in mm–4 x Angina Index). Results. DTS was lower in women as compared to men: 2.54±5.36 vs. 6±4.69, p=0.0006. 54.28% of the patients were ranged with a low DTS risk category, whereas 45.71% belonged to a moderate and high risk category. DTS was significantly lower in women than in men with high blood pressure (2.03±4.8 vs. 5.8±4.28), hypercholesterolemia (1.14±4.51 vs. 6.24±4.13), diabetes mellitus (1.83 ± 3.73 vs. 6.13±4.8), and obesity (2.42±5.35 vs. 5.81±4.64). By analyzing the presence of cardiovascular risk factors only in women, we noticed that only those with high blood pressure (2.03±4.89 vs. 8.13 ±7.85) and hypercholesterolemia (2.31±4.76 vs. 3.89±5.95) had a statistically significant low DTS (p<0.05). In conclusion, our research, which showed differences in DTS between women and men, raises concerns about the early diagnosis of ischemic heart disease in women.

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Cardiovascular Risk Factors and their Relationship with Endothelial Dysfunction in Rural and Urban South African Children

10.21203/rs.3.rs-54162/v1 ◽

2020 ◽

Author(s):

Edna N. Matjuda ◽

Godwill Azeh Engwa ◽

Samuel Nkeh Chungag Anye ◽

Benedicta N. Nkeh Chungag ◽

Nandu Goswami

Keyword(s):

Risk Factors ◽

Blood Pressure ◽

Cardiovascular Risk ◽

Endothelial Dysfunction ◽

Cardiovascular Risk Factors ◽

High Blood Pressure ◽

Urban Children ◽

Urban Settings ◽

Arterial Blood ◽

Rural And Urban

Abstract Background: Endothelial dysfunction is known to be an initiator to the development and progression of atherosclerotic cardiovascular disease (CVD). However, there is paucity o knowledge on its relationship with cardiovascular risk factors in children. More so, some of these cardiovascular risk factors are known to be influenced by feeding habits and life style changes which often vary between rural and urban settings. This study was aimed to investigate the relationship between cardiovascular risk factors and endothelial function in rural and urban children. Methods: A cross-sectional study on 6-9 years old children in randomly selected rural and urban schools of the Eastern Cape Province of South Arica was conducted. General anthropometric indices were measured followed by blood pressure (BP) measurements. The pulse wave velocity (PWV) was measured using a Vicorder. Urine sample was collected for the determination of albumin, creatinine, asymmetric dimethylarginine (ADMA), 8-hydroxy-2deoxyguanosine (8-OHdG) and thiobarbituric acid reactive substance (TBARS). Albumin to creatinine ratio (ACR) was calculated.Results: Children from urban settings (10.8%) had a higher prevalence of overweight/obesity than their rural counterparts (8.5%) while the prevalence of elevated/high blood pressure was higher in rural children (23.2%) than in urban children (19.0%). Diastolic blood pressure (DBP) and mean arterial blood pressure (MAP) significantly (p<0.005) increased with increasing quartiles of PWV. ADMA positively associated with HR in rural girls and showed a weak risk for elevated SBP and MAP. Body mass index (BMI) increased with increasing PWV and predicted endothelial dysfunction. 8-OHdG significantly (p<0.005) increased with increasing quartiles of ADMA and positively correlated with ADMA. Creatinine, albumin and ACR significantly (p<0.005) increased with increasing ADMA and ADMA associated positively with creatinine. Conclusion: Endothelial dysfunction was associated with obesity, high blood pressure, oxidative stress and microalbuminuria in children, and this relationship varied between rural and urban children.

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1P-0076 High blood pressure and associated cardiovascular risk factors in Iran: IHHP

Atherosclerosis Supplements ◽

10.1016/s1567-5688(03)90151-6 ◽

2003 ◽

Vol 4 (2) ◽

pp. 36

Author(s):

M. Sadeghi ◽

H.R. Roohafza

Keyword(s):

Risk Factors ◽

Blood Pressure ◽

Cardiovascular Risk ◽

Cardiovascular Risk Factors ◽

High Blood Pressure

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Antihypertensive Drug Regimen for High Blood Pressure Associated with Modifiable Cardiovascular Risk Factors Among Hypertensive Patients Attending Campus Teaching Hospital of Lomé, Togo, West Africa

Journal of Pharmaceutical and Pharmacological Sciences ◽

10.29011/2574-7711.100076 ◽

2018 ◽

Vol 3 (1) ◽

Author(s):

Yao Potchoo

Keyword(s):

Risk Factors ◽

Blood Pressure ◽

Cardiovascular Risk ◽

West Africa ◽

Cardiovascular Risk Factors ◽

High Blood Pressure ◽

Antihypertensive Drug ◽

Teaching Hospital ◽

Drug Regimen ◽

Hypertensive Patients

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Abstract P387: Cardiovascular Risk Factors Among Children in a 20 year Community Study: Influence of the Family

Circulation ◽

10.1161/circ.125.suppl_10.ap387 ◽

2012 ◽

Vol 125 (suppl_10) ◽

Author(s):

Tracy L Nelson ◽

Laura Dvorak ◽

Kathy Kioussopoulos ◽

Gary Luckasen

Keyword(s):

Risk Factors ◽

Blood Pressure ◽

Cardiovascular Risk ◽

Total Cholesterol ◽

Cardiovascular Risk Factors ◽

Family Member ◽

High Blood Pressure ◽

High Cholesterol ◽

Northern Colorado ◽

The Family

Background: High cholesterol, atherosclerosis, high blood pressure, and obesity can be identified during childhood. Identifying the underlying contributors to such risk factors may allow young families the opportunity to modify health habits. The purpose of this study was to determine the prevalence of cardiovascular risk factors and their associated predictors among Northern Colorado children and their families. Methods: The Poudre Valley Health System (PVHS), Healthy Hearts Club has provided a successful cardiovascular screening program for the past ∼20 years (1993–2011) to identify risk factors among students in six Northern Colorado school districts (a primarily white population ∼90%). Schools were selected based on willingness to participate. Data were collected cross-sectionally with objective measures of total cholesterol, high-density lipoprotein cholesterol (HDL-C), blood pressure and body mass index (BMI). Surveys were filled out by the parent and/or legal guardian and included questions about diet and physical activity of the child as well as these behaviors and risk factors among family members. Results: There were 9,363 children with information for the measured risk factors (mean age, 10.4 years, range, 6.2–18 years, 49% female). The prevalence of the six measured risk factors included 39% with total cholesterol > 170 mg/dl, 10.7%, with HDL-C < 35 mg/dl, 11.7% with Cholesterol/HDL ratio >4.8, 7.2% with systolic blood pressure > 120 mmHg, 8.2% with diastolic blood pressure > 80 mmHg and 21.1% with BMI > 85 percentile for age and sex. There were 40.8%, 35%, 14.5%, 6.2%, 2.4%, 0.8% and 0.2% with 0–6 risk factors respectively. Of those with zero risk factors 25.7% reported a family member (other than the child) being overweight while 68.2% reported such among those with five risk factors; similarly 16.4% reported a family member who smokes (among children with zero risk factors) as compared to 24% with five risk factors. High cholesterol, high blood pressure and diabetes trended similar. Conclusions: The prevalence of CVD risk factors among these children is substantial and is associated with such risk factors among the family. This data suggests risk factor reduction must not be done in isolation of the family.

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Abstract WP241: Prevalence of Subclinical Extracranial Carotid Atherosclerosis Detected by Ultrasound Among Amerindians: A Population Study in Rural Ecuador

Stroke ◽

10.1161/str.51.suppl_1.wp241 ◽

2020 ◽

Vol 51 (Suppl_1) ◽

Author(s):

Victor J Del Brutto ◽

Jose G Romano ◽

Robertino M Mera ◽

Jonathan P Amodio ◽

Tatjana Rundek ◽

...

Keyword(s):

Risk Factors ◽

Blood Pressure ◽

Cardiovascular Risk ◽

Cardiovascular Risk Factors ◽

High Blood Pressure ◽

Carotid Atherosclerosis ◽

Male Gender ◽

Rural Setting ◽

Carotid Plaques ◽

The Mean

Background: Epidemiological information on extracranial carotid atherosclerosis (ECA) among Amerindians is limited. We aim to determine the prevalence of subclinical ECA and its correlation with cardiovascular risk factors in community-dwelling adults of Amerindian ancestry living in a rural Ecuadorian village. Methods: Utilizing a population-based design, stroke-free individuals aged ≥40 years were invited to undergo carotid ultrasound. Subclinical ECA was defined as an intima-media thickness (cIMT) >1mm and/or the presence of carotid plaques (focal intima thickening >1.5mm that protrudes into the lumen). Degree of luminal stenosis was calculated and considered significant if >50%. We investigated the association between these biomarkers and cardiovascular risk factors. Results: Of 728 candidates, 559 (77%) stroke-free individuals underwent carotid sonographic evaluation and were included. The mean age was 62.3 ±12.5 and 238 (43%) were men. The mean value of the cIMT was 0.85 ± 0.17mm (median cIMT: 0.83mm; IQ range: 0.74-0.92 mm). The prevalence of increased cIMT, carotid plaques, and increased cIMT and/or carotid plaques were 14%, 23.8%, and 26.1%, respectively. Table depicts the association of these biomarkers with cardiovascular risk factors. A multinomial logistic regression model, using individuals with normal carotids as the referent category, showed significant associations of ECA with increasing age, male gender, smoking and high blood pressure. Significant carotid stenosis was found in 19 subjects (3.4%). Conclusions: About one-fourth of Amerindians living in a rural setting have subclinical ECA. Increasing age, male gender, smoking and high blood pressure were independent determinants of the burden of ECA, while elevated glucose and total cholesterol showed no significant association. Obesity was inversely associated with ECA in univariate analysis, but such association disappeared in the multivariate model.

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