EFFECT OF MATERNAL ATHYREOSIS ON RAT EMBRYOS DURING THE LATE PHASE OF ORGANOGENESIS
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ABSTRACT In order to elucidate the question whether maternal thyroid hormones are necessary for both growth and differentiation processes during the phase of organogenesis, rats were thyroidectomized on day 6 of gestation (under barbiturate anaesthesia) using a stereomicroscope. Two days after the operation a radio-iodine-test was performed which ensured that only athyroid animals were used for the experiments. The results of the studies on the growth kinetics of 11- to 14-day-old rat embryos as well as on the activity of the DNA-dependent RNA polymerases and the α-glycerophosphate oxidase in rat embryos of operated mother animals showed that thyroid hormones are not required for the early stages of development of rats.
2004 ◽
Vol 40
(2)
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pp. 176-181
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1970 ◽
Vol 28
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pp. 440-441
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