scholarly journals Effects of feeding tuna oil on the lipid composition of pig spermatozoa and in vitro characteristics of semen

Reproduction ◽  
2001 ◽  
Vol 121 (2) ◽  
pp. 315-322
Author(s):  
J. Rooke
Keyword(s):  
Lipid Composition ◽  
Tuna Oil

Inhibition of Platelet Aggregation by Ethanol in Vitro Shows Specificity for Aggregating Agent Used and Is Influenced by Platelet Lipid Composition

1982 ◽  
Vol 48 (01) ◽  
pp. 049-053 ◽  
Author(s):  
C G Fenn ◽  
J M Littleton
Keyword(s):  
Platelet Aggregation ◽  
Lipid Composition ◽  
Saturated Fatty Acids ◽  
Calcium Ionophore ◽  
Cholesterol Content ◽  
Membrane Lipid ◽  
Calcium Ionophore A23187 ◽  
Ionophore A23187 ◽  
Increased Sensitivity

SummaryEthanol at physiologically tolerable concentrations inhibited platelet aggregation in vitro in a relatively specific way, which may be influenced by platelet membrane lipid composition. Aggregation to collagen, calcium ionophore A23187 and thrombin (low doses) were often markedly inhibited by ethanol, adrenaline and ADP responses were little affected, and aggregation to exogenous arachidonic acid was actually potentiated by ethanol. Aggregation to collagen, thrombin and A23187 was inhibited more by ethanol in platelets enriched with saturated fatty acids than in those enriched with unsaturated fats. Platelets enriched with cholesterol showed increased sensitivity to ADP, arachidonate and adrenaline but this increase in cholesterol content did not appear to influence the inhibition by ethanol of platelet responses. The results suggest that ethanol may inhibit aggregation by an effect on membrane fluidity and/or calcium mobilization resulting in decreased activity of a membrane-bound phospholipase.

scholarly journals A Shift in Glycerolipid Metabolism Defines the Follicular Fluid of IVF Patients with Unexplained Infertility

Biomolecules ◽  
2020 ◽  
Vol 10 (8) ◽  
pp. 1135
Author(s):  
Albert Batushansky ◽  
Anish Zacharia ◽  
Alaa Shehadeh ◽  
Reut Bruck-Haimson ◽  
Daniel Saidemberg ◽  
...  
Keyword(s):  
Follicular Fluid ◽  
Lipid Composition ◽  
Age Groups ◽  
Positive Outcome ◽  
Unexplained Infertility ◽  
The Body ◽  
Male Factor ◽  
Vitro Fertilization ◽  
Infertility Patients

Follicular fluid (FF) constitutes the microenvironment of the developing oocyte. We recently characterized its lipid composition and found lipid signatures of positive pregnancy outcome after in vitro fertilization (IVF). In the current study, we aimed to test the hypothesis that unexplained female infertility is related to lipid metabolism, given the lipid signature of positive-outcome IVF patients we previously found. Assuming that FF samples from IVF patients with male factor infertility can represent a non-hindered metabolic microenvironment, we compared them to FF taken from women with unexplained infertility. FF from patients undergoing IVF was examined for its lipid composition. We found highly increased triacylglycerol levels, with a lower abundance of monoacylglycerols, phospholipids and sphingolipids in the FF of patients with unexplained infertility. The alterations in the lipid class accumulation were independent of the body mass index (BMI) and were altogether kept across the age groups. Potential lipid biomarkers for pregnancy outcomes showed a highly discriminative abundance in the FF of unexplained infertility patients. Lipid abundance distinguished IVF patients with unrecognized infertility and provided a potential means for the evaluation of female fertility.

DIETARY LIPIDS, INFECTION AND MACROPHAGE PROCOAGULANT ACTIVITY

1987 ◽  
Author(s):  
M C E van Dam-Mieras ◽  
A D Muller ◽  
G Hornstra
Keyword(s):  
Lipid Composition ◽  
Cell Types ◽  
Dietary Lipid ◽  
Infection Process ◽  
Dietary Lipids ◽  
Procoagulant Activity ◽  
Morphological Evidence ◽  
Blood Monocytes ◽  
Peripheral Blood Monocytes

It is generally accepted that the type of dietary fat influences arterial thrombosis and atherosclerosis. Although it is still largely unknown how the dietary lipid composition influences the process of atherogenesis, it is evident that several cell types are involved. Morphological evidence for the involvement of monocyte/macropages has been given.We described before that the dietary lipid composition has striking effects on the procoagulant activity of macrophages. When macrophages were isolated from the spleens of healthy rats the procoagulant activity slightly decreased during the first few hours after isolation, and reached a plateau value after 4 hours. When, however, macrophages were obtained from animals infected with a pneumona virus (PVM) different results were obtained:Experiments carried out with peripheral blood monocytes showed close resemblance to those described in the table.These results show that:- moncytes/macrophages isolated from PVM-infected animals increase their procoagulant activity during in vitro culture- the differences in macrophage procoagulant activity found in cells obtained from healthy animals fed diets containing different lipids no longer were found in PVM-infected animalsThis would implicate that the infection process has a more profound influence on macrophage procoagulant activity that the composition of the diet

scholarly journals FTIR Spectroscopy to Reveal Lipid and Protein Changes Induced on Sperm by Capacitation: Bases for an Improvement of Sample Selection in ART

2020 ◽  
Vol 21 (22) ◽  
pp. 8659
Author(s):  
Maria Pachetti ◽  
Luisa Zupin ◽  
Irene Venturin ◽  
Elisa Mitri ◽  
Rita Boscolo ◽  
...  
Keyword(s):  
Lipid Composition ◽  
Semen Quality ◽  
Sperm Quality ◽  
Sample Selection ◽  
Poor Quality ◽  
Interesting Possibility ◽  
The Many ◽  
Α Helix ◽  
Analytical Approaches

Although being a crucial step for Assisted Reproduction Technologies (ART) success, to date sperm selection is based only on morphology, motility and concentration characteristics. Considering the many possible alterations, there is a great need for analytical approaches allowing more effective sperm selections. The use of Fourier Transform Infrared (FTIR) may represent an interesting possibility, being able to reveal many macromolecular changes in a single measurement in a nondestructive way. As a proof of concept, in this observational study, we used a FTIR approach to reveal features related to sperm quality and chemical changes promoted by in vitro capacitation. We found indication that α-helix content is increased in capacitated sperm, while high percentages of the β-structures seem to correlate to poor-quality spermatozoa. The most interesting observation was related to the lipid composition, when measured as CH2/CH3 vibrations (ratio 2853/2870), which resulted in being strongly influenced by capacitation and well correlated with sperm motility. Interestingly, this ratio is higher than 1 in infertile samples, suggesting that motility is related to sperm membranes stiffness and lipid composition. Although further analyses are requested, our results support the concept that FTIR can be proposed as a new smart diagnostic tool for semen quality assessment in ART.

Lipid composition modulates the intestine digestion rate and serum lipid status of different edible oils: a combination of in vitro and in vivo studies

2019 ◽  
Vol 10 (3) ◽  
pp. 1490-1503 ◽  
Author(s):  
Zhan Ye ◽  
Chen Cao ◽  
Ruizhi Li ◽  
Peirang Cao ◽  
Qiu Li ◽  
...  
Keyword(s):  
Lipid Composition ◽  
Serum Lipid ◽  
Edible Oils ◽  
In Vivo Studies ◽  
Digestion Rate ◽  
Lipid Status

The objective of the present study was to investigate the connections between lipid compositions and the digestion and absorption differences of different lipids.

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