scholarly journals Gigantinė retroperitoninio tarpo lipoma: klinikinis atvejis ir literatūros apžvalga

2012 ◽  
Vol 10 (1-2) ◽  
pp. 0-0
Author(s):  
Edgaras Kulikauskas ◽  
Eligijus Poškus ◽  
Dileta Rutkauskaitė ◽  
Kęstutis Strupas
Keyword(s):  
Large Mass ◽  
University Hospital ◽  
Pathological Examination ◽  
Low Grade ◽  
Vilnius University ◽  
Grade Malignancy ◽  
The Right ◽  
E Mail ◽  
Slow Growing ◽  
Primary Retroperitoneal

Edgaras Kulikauskas1, Eligijus Poškus1, Dileta Rutkauskaitė2, Kęstutis Strupas1 1Vilniaus universiteto ligoninės Santariškių klinikų Gastroenterologijos, nefrologijos, urologijos ir abdominalinės chirurgijos klinika, Santariškių g. 2, LT-08661 Vilnius2Vilniaus universiteto Medicinos fakulteto Krūtinės ligų, alergologijos ir radiologijos klinika, Santariškių g. 2, LT-08661 Vilnius El. paštas: [email protected] Pirminiai retroperitoniniai navikai yra reti, pasižymintys didele histologine įvairove. Apie 80 proc. pirminių retroperitoninio tarpo navikų yra piktybiniai, o gerybinės lipomos šioje vietoje aptinkamos labai retai. Augdamos lėtai lipomos gali pasiekti 20 cm dydį ir kelių kilogramų svorį, nesukeldamos ryškesnės simptomatikos. Šių nepiktybinių navikų diagnostika remiasi radiologiniais tyrimais. Atskirti lipomas nuo piktybinių riebalinių navikų, ypač geros diferenciacijos liposarkomomis, kurios retai metastazuoja, tačiau pasižymi dideliu recidyvų dažnumu, gali būti labai sudėtinga. Dėl šių priežasčių riebaliniai retroperitoninio tarpo navikai turi būti vertinami kaip liposarkomos, kol neįrodoma kitaip. Radikalus chirurginis naviko pašalinimas yra pirmiausia pasirenkamas gydymo metodas.Pateikiame klinikinį retroperitoninės lipomos, nustatytos 61 metų amžiaus vyrui, gydymo atvejį. Navikas diagnozuotas remiantis klinika ir kompiuterinės tomografijos tyrimu. Operacijos metu rasta ir pašalinta 40 × 40 × 20 cm dydžio, 6500 g svorio lipoma, diagnozė patvirtinta histologinio tyrimo metu. Devintą parą po operacijos, ligonis išrašytas į namus. Reikšminiai žodžiai: retroperitoninis tarpas, lipoma, chirurgija. Giant retroperitoneal lipoma: case report and literature review Edgaras Kulikauskas1, Eligijus Poškus1, Dileta Rutkauskaitė2, Kęstutis Strupas1 1Clinic of Gastroenterology, Urology and Abdominal Surgery, Vilnius University Hospital “Santariškių klinikos”, Santariškių Str. 2, LT-08661 Vilnius, Lithuania2Vilnius University, Medical Faculty, Clinic of Chest Diseases, Allergology and Radiology, Santariškių Str. 2, LT-08661 Vilnius, Lithuania E-mail: [email protected] Primary retroperitoneal tumours are rare and show a high histological variety. About 80% of retroperitoneal tumours are malignant; benign lipomas in this location are exceptionally rare. These slow-growing tumors can grow up to more than 20 cm and weight a few kilograms. The differential diagnosis of lipomas with liposarcomas may be problematic, especially for tumours with low-grade malignancy, which have a predilection for local recurrence but do not generally metastatize. Fatty tumours of the retroperitoneum should be considered to be potential liposarcomas until proven otherwise, and a radical lesion excision should always be performed, if possible.We report a case of a giant retroperitoneal lipoma in a 61-year-old male. A CT scan of his abdomen showed a large mass of fat density displacing organs to the right side. The patient underwent a radical tumour excision. Laparotomy showed a giant fatty mass measuring 40 x 40 x 20 cm and weighing 6500 g. The pathological examination revealed benign lipoma. The patient was discharged home on postoperative day 9. Key words: retroperitoneal space, lipoma, surgery

scholarly journals Primitive myxoid mesenchymal tumor of infancy in scrotum: A case report and literature review

2021 ◽  
Author(s):  
Chunsen Li ◽  
Mengqiao Wang ◽  
Hongwei Dang ◽  
Yan Pan ◽  
Yi Liu ◽  
...  
Keyword(s):  
Good Condition ◽  
B Cell Lymphoma ◽  
Mesenchymal Tumor ◽  
Proliferation Index ◽  
Pathological Examination ◽  
Low Grade ◽  
Ki 67 ◽  
Grade Malignancy ◽  
One Year ◽  
The Right

Abstract BackgroundPrimitive myxoid mesenchymal tumor of infancy (PMMTI) is a rare tumor and its molecular mechanism and prognosis remain unclear. We here report a case of PMMTI, and review the reported literature of PMMTI.Case presentationA one-year-old boy found a lump in his right groin. The size of the mass was 1 cm×1 cm. Computed tomography showed a round, slightly dense shadow of 38 mm×32 mm in the right groin. The tumor was removed for pathological examination, and the size of the tumor was 6.0 cm×5.0 cm×3.0 cm. Tumor cells are diffusely distributed, mainly spindle cells. The blood vessels were abundant, many adipocytes can be observed in some areas, and focal lymphocyte infiltration can be seen in a few areas. Immunophenotype was as follows: histone H3 at lysine 27 (H3K27me3), B-cell lymphoma 6 corepressor (BCOR) and Bcl-2 were positive, cluster of differentiation 99 (CD99) showed diffuse reactivity, BCL6 was scattered positive, Ki-67 proliferation index was 20%. Dual-color fluorescence in situ hybridization (FISH) showed red and green signal nuclei caused by the deletion of ETV6 gene rearrangement. The patient underwent extensive surgical resection during the recurrence period and was in good condition 7 months later.ConclusionsPMMTI is at least a low-grade malignancy. BCOR, BCL2, BCL6, and CD99 can be used as special IHC markers, and most PMMTI cases exhibit BCOR ITD change. H3K27me3 may be used as a new IHC marker for PMMTI.

scholarly journals Varikocelės gydymas naudojant mikrochirurginį metodą

2012 ◽  
Vol 10 (1-2) ◽  
pp. 0-0
Author(s):  
Tigran Zotov ◽  
Deimantas Šukys
Keyword(s):  
Surgical Treatment ◽  
Sperm Quality ◽  
Testicular Volume ◽  
University Hospital ◽  
Adult Males ◽  
Sperm Analysis ◽  
Postoperative Control ◽  
Vilnius University ◽  
The Republic ◽  
E Mail

Tigran Zotov, Deimantas Šukys Respublikinės Vilniaus universitetinės ligoninės Urologijos skyrius, Šiltnamių g. 29, LT-04130 Vilnius El. paštas: [email protected] Įvadas Varikocelė yra gan dažna liga, nustatoma 10 proc. suaugusių vyrų, ir net 25 proc. tų vyrų, kurie tiriami dėl nevaisingumo. Varikocelė mažina sėklidžių apimtį, blogina spermos kokybę ir Leidigo ląstelių funkciją. Po varikocelės gydymo sėklidė padidėja, pagerėja spermos kokybė. Respublikinėje Vilniaus universitetinėje ligoninėje buvo pradėta naudoti mikrochirurginė varikocelės gydymo metodika. Metodai Nuo 2009 m. balandžio iki 2011 m. gegužės buvo atliktos septynios varikocelektomijos operacijos naudojant mikrochirurginę techniką. Rezultatai Intraoperacinių ar ankstyvųjų pooperacinių komplikacijų nebuvo. Iškvietus pakartotinio patikrinimo operuotus pacientus nerasta nė vieno varikocelės recidyvo. Išvados Varikocelė yra gan dažna liga, galinti lemti nevaisingumą. Dėl nevaisingumo besikreipiantiems vyrams, kuriems yra klinikinė varikocelės raiška ir nenormalius spermos tyrimas, indikuojamas operacinis gydymas. Jei yra galimybė pasinaudoti operaciniu mikroskopu, tikslinga atlikti mikrochirurginę varikocelektomiją, o jei tokios galimybės nėra, pirmučiausia alternatyva yra laparoskopinė varikocelektomija. Reikšminiai žodžiai: varikocelė, chirurginis gydymas. Varicocele treatment by the microsurgical method Tigran Zotov, Deimantas Šukys Republican Vilnius University Hospital, Department of Urology, Šiltnamių Str. 29, LT-04130 Vilnius, Lithuania E-mail: [email protected] Background Varicocele is a rather frequent disease found in 10% of adult males and in 25% of infertile men. Varicocele reduces the testicular volume, declines sperm quality and the function of the Leydig cells. After varicocele treatment, the testicular volume increases and sperm quality improves. Varicocele treatment by the microsurgical method was started at the Republic Vilnius University Hospital. Methods Seven varicocelectomies by the microsurgical way were performed from April 2009 till May 2011. Results No intraoperative or early postoperative complications were observed. There was no varicocele recurrences found on postoperative control visits. Conclusions Varicocele is a rather frequent disease which can cause infertility. Its surgical treatment is indicated in cases of a clinically apparent varicocele and abnormal sperm analysis. If possible (where a surgical microscope is accessible), microsurgical varicocelectomy is the preferred way of treatment. Laparoscopic varicocelectomy is the method of choice if there is no possibility to perform a microsurgical procedure. Key words: varicocele, surgical treatment

scholarly journals Mammary analogue secretory carcinoma: a rare salivary gland tumor

2020 ◽  
Vol 6 (5) ◽  
pp. 998
Author(s):  
Shashikant Anil Pol ◽  
Surinder K. Singhal ◽  
Nitin Gupta ◽  
Himanshu Bayad
Keyword(s):  
Salivary Gland ◽  
Salivary Gland Tumor ◽  
Needle Aspiration ◽  
Good Prognosis ◽  
Low Grade ◽  
Secretory Carcinoma ◽  
Mammary Analogue Secretory Carcinoma ◽  
Grade Malignancy ◽  
Enhanced Computed Tomography ◽  
Slow Growing

<p>Mammary analogue secretary carcinoma are salivary gland tumors similar to secretary carcinoma of breast histologically. It usually affects adults with mean age group of 45 years. Clinically it is usually slow growing, low grade malignancy with favorable prognosis. We are reporting a case of 47 years old female presented with complaints of swelling behind left ear for last 7 years. It was slow growing, painless and persistent. On examination, 4 x 3 cm swelling was present just below left ear lobule. It was nontender, firm, irregular in shape with smooth surface with slight mobility and overlying skin pinchable. Fine needle aspiration cytology suggested benign tumor with cystic change. On contrast enhanced computed tomography scan, there was a lobulated hypodense lesion measuring 24×35×32 mm with internal septations and enhancement of wall in expected location of superficial as well as deep lobe of left parotid gland. Patient underwent left total conservative parotidectomy and histopathology came out to be secretory analogue mammary carcinoma. Subsequently she received post-operative radiotherapy. Patient is on regular follow up and disease free till date. Usually mammary analogue secretory carcinoma is a low-grade malignancy with good prognosis. Immunohistochemistry is confirmatory which shows positivity for S-100 protein and mammaglobin.</p>

scholarly journals Low-Grade Fibromyxoid Sarcoma of the Lateral Skull Base: Presentation of Two Cases

2019 ◽  
Vol 2019 ◽  
pp. 1-6
Author(s):  
Evgenia Chetverikova ◽  
Priit Kasenõmm
Keyword(s):  
Malignant Tumour ◽  
Low Grade ◽  
Loss Of Consciousness ◽  
First Case ◽  
Clinical Presentations ◽  
Lateral Skull Base ◽  
Fibromyxoid Sarcoma ◽  
Gag Reflex ◽  
The Right ◽  
Slow Growing

Low-grade fibromyxoid sarcoma (LGFMS) is a rare slow-growing malignant tumour with a deceptively benign histologic appearance. Herein, we report two cases of LGFMS with variable clinical presentations. The first case was a 17-year-old female who referred to our department due to deaf ear on the right together with ipsilateral gag reflex impairment and globus sensation in the pharynx. The second case was a 35-year-old female with recurrent LGFMS, suffering from headaches, vertigo, and episodes of loss of consciousness. LGFMS of the temporal bone is a rare pathology, and to the best of our knowledge, no such cases have been reported before.

scholarly journals The Pattern of Colorectal Cancer Surgery in Lithuania in 2005: Do Results Meet Expectations?

Medicina ◽  
2013 ◽  
Vol 49 (3) ◽  
pp. 20 ◽  
Author(s):  
Eligijus Poškus ◽  
Saulius Mikalauskas ◽  
Valdemaras Jotautas ◽  
Paulius Žeromskas ◽  
Tomas Poškus ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Postoperative Complications ◽  
Demographic Data ◽  
Preoperative Evaluation ◽  
University Hospital ◽  
Pathological Examination ◽  
National Database ◽  
Resection Margins ◽  
Neoadjuvant Radiotherapy ◽  
Vilnius University

The aim of this study was to expose the pattern of the surgical treatment of colorectal cancer in Lithuania in 2005. Material and Methods. A retrospective analysis of 590 patients treated for colorectal cancer in the surgical departments of the Hospital of Lithuanian University of Health Sciences, the Institute of Oncology of Vilnius University, and Vilnius University Hospital Santariškių Klinikos in 2005 was performed. Demographic data, preoperative evaluation, postoperative complications assessed according to the Clavien-Dindo classification, the quality of pathological examination, and survival rates were analyzed. Results. A total of 590 patients, 269 women (45.6%) and 321 men (54.4%), were included in this study; the mean age was 68.3 years (SD, 11.2). Tumors were found in the colon of 274 patients (46.4%) and in the rectum of 316 patients (53.6%). An abdominal ultrasound scan was preoperatively performed in 516 patients (87.5%) and a chest x-ray in 316 patients (53.6%); 35 patients (5.9%) underwent abdominal computed tomography. Endorectal ultrasound was done in 99 (31.7%) cases. Neoadjuvant radiotherapy for T3 and T4 rectal tumors was applied in 42 cases (18.1%). Besides, 211 patients (35.8%) developed postoperative complications with an anastomotic leak emerging in 20 cases (3.4%). Death occurred in 7 patients (1.18%). On the average, 11.15 lymph nodes (SD, 6.02) were found in pathological specimens. Circumferential resection margins were assessed in 58 cases (18.4%). The overall 5-year survival rate was 52.06%. Conclusions. The preoperative evaluation and the treatment of patients with colorectal cancer were not sufficiently consistent in Lithuania in 2005. In order to improve the treatment of colorectal cancer, standardization or the national database of colorectal cancer is necessary.

scholarly journals Ovarian Dysgerminoma with Metastases in Supraclavicular Lymph Nodes Diagnosed in a 16-year-old Girl: Clinical Case and Literature Review

2018 ◽  
Vol 17 (3-4) ◽  
pp. 250-255
Author(s):  
Diana Maldžiūtė ◽  
Vilma Rukauskaitė ◽  
Kęstutis Trainavičius
Keyword(s):  
Ovarian Tumor ◽  
Stage Iv ◽  
Figo Stage ◽  
University Hospital ◽  
Histological Evaluation ◽  
Supraclavicular Lymph Nodes ◽  
Before And After ◽  
Ovarian Dysgerminoma ◽  
Vilnius University ◽  
The Right

[full article, abstract in English; abstract in Lithuanian] Background Tumors of children reproductive system are rare, the most frequent among them is ovarian tumor. The most frequent histological type of ovarian tumor in girls and adolescents is germ cell tumor, with dysgerminoma being the most frequent of all. Symptoms are very non-specific, this is why these tumors are often diagnosed late. Dysgerminoma is a malignant tumor, thus if not treated, it may be potentially lethal. Case report We present a 16-year old patient, who has come to Vilnius University Hospital Santaros Klinikos, Children’s unit, due to a sudden emergence of a growth above the left clavicle. The girl did not have any other specific complaints. Huge hard growth was founded during palpation of the abdomen. After the cancer marker test (alfa-fetoprotein – 1,9 kU/L, beta-human chorionic gonadotropin – 1231.0 U/L; lactate dehydrogenase – 2721.0 U/L; Ca125 – 665.8 kU/L), pelvic ultrasound examination, computed tomography and histological evaluation of the supraclavicular mass, dysgerminoma of the right ovary FIGO stage IV was diagnosed. The patient was treated with laparotomic oophorectomy and chemotherapy before and after surgery. Treatment was successful as 100% of tumor cells necrosis was achieved. Conclusions Girls and adolescents should be suspect to ovarian masses if they complains about abdominal pain, a growth in the abdominal area, disruptions of menstrual cycle or signs of premature puberty. Early diagnosis and treatment of ovarian dysgerminoma have a very good recovery rate in girls and adolescent.

scholarly journals Clinicopathologic characteristics of primary pleural epithelioid hemangioendothelioma

2011 ◽  
Vol 4 (4) ◽  
pp. 219
Author(s):  
Chad A. Reade ◽  
Apar Kishor Ganti ◽  
Anne Kessinger
Keyword(s):  
Spontaneous Remission ◽  
Epithelioid Hemangioendothelioma ◽  
Low Grade ◽  
Clinicopathologic Characteristics ◽  
Short Survival ◽  
History Of ◽  
Therapeutic Measures ◽  
Long Life ◽  
Grade Malignancy ◽  
The Right

Epithelioid hemangioendothelioma (EHE) is a rare vascular-derived malignancy. Within the thorax, EHE originating in the pleura is less often reported than EHE originating in the lung. Pulmonary EHE has been referred to as a borderline or low-grade malignancy that exhibits an unpredictable course. It often is associated with a long life expectancy and occasional spontaneous remission. Because the natural history of pleural EHE is less well understood, a literature review was conducted to investigate the characteristics of the disease. Twenty-two cases of pleural EHE were identified. The disease occurred more often in men than women, appeared in the right thorax more often than the left, exhibited a virulent course, was usually refractory to systemic therapy, and was often associated with a short survival. These characteristics differ substantially from those of pulmonary EHE and suggest that the clinician should approach pleural EHE anticipating an especially aggressive malignancy which likely will not respond to current therapeutic measures.

scholarly journals Unusual biological behavior of femoral liposarcoma

2007 ◽  
Vol 135 (7-8) ◽  
pp. 468-471 ◽  
Author(s):  
Milan Stojanovic ◽  
Branislav Goldner ◽  
Spasenija Djukic
Keyword(s):  
Biological Behavior ◽  
Low Grade ◽  
High Grade ◽  
Therapeutic Protocol ◽  
Grade Of Malignancy ◽  
Males And Females ◽  
Grade Malignancy ◽  
The Right ◽  
High Grade Malignancy ◽  
Scapular Region

Introduction Liposarcoma of a bone is a very rare tumor of the fatty marrow, originating from lipoblasts. Its frequency is 1:1000 of all bone tumors. The long bones and the lower extremities are predominantly affected, equally in males and females between 30 and 70 years of age. In the estimation of its biological behavior, histological graduation (G), the surgical localization of the tumor (T) and the presence or absence of metastases (M), are very important. A tumor with low grade differentiation, with transosseal propagation and metastases, has a poor prognosis. Surgical resection-amputation, chemotherapy and radiotherapy are the therapeutic methods of choice. Case outline Twelve years ago, in a 58-year old man, there was a radiologically diagnosed sarcoma in the lower part of the right femur manifested with painful swelling in that region. The high suprapatellar amputation was done. There was a histologically proved liposarcoma of a high grade of malignancy. According to the therapeutic protocol, chemotherapy and radiotherapy were applied. During the period of 12 years, the patient had a relapse on the stump, metastatic dissemination in the soft tissue of small pelvis twice, once in the left scapular region and in the inguinal lymph nodes, six operations and 8-year accumulation of metastatic deposits in the lung. Now, the patient feels relatively well, mobile, and walks 5 kilometres every day. Conclusion Unusual behaviour of the liposarcoma of high grade malignancy with which the patient has been living for 12 years, could be explained by the patient?s strong immunobiological system in the struggle to retain its vitality and mobility.

Synchronous cystic teratomas of the craniofacial region

2003 ◽  
Vol 117 (10) ◽  
pp. 824-826
Author(s):  
Neena Chaudhary ◽  
Krishna Pal Singh Malik ◽  
Alok Gupta ◽  
Anil Kumar Rai ◽  
Pankaj Gupta ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Pathological Examination ◽  
Resonance Imaging ◽  
Mri Scan ◽  
Temporal Fossa ◽  
Magnetic Resonance Imaging Mri ◽  
The Right ◽  
Slow Growing

A case of synchronous cystic teratomas presented with the complaints of a slow-growing facial mass and forward protrusion of the right eye since birth. The patient was examined thoroughly and subjected to magnetic resonance imaging (MRI) scan. The MRI scan revealed the presence of two separate cysts in the right orbit and right temporal fossa. The patient was operated by a combined effort of ophthalmologists and otorhinolaryngologists. The cysts were excised and subjected to pathological examination. The histopathological survey revealed both the cysts to be mature cystic teratomas similar to each other. This coexistence of a primary temporal fossa teratoma with an orbital teratoma is the first of its kind and to the best of our knowledge has not been reported before.

scholarly journals Novel intronicDICER1variation associated with pleuropulmonary blastoma in two siblings

2019 ◽  
Vol 12 (1) ◽  
pp. e227391
Author(s):  
Bruce D Leckey ◽  
John M Carney ◽  
Jessica M Sun ◽  
Elizabeth N Pavlisko
Keyword(s):  
Lower Lobe ◽  
Large Mass ◽  
Pathological Examination ◽  
Pleuropulmonary Blastoma ◽  
Upper Respiratory Tract ◽  
Basal Segment ◽  
Lung Malignancies ◽  
History Of ◽  
Upper Respiratory ◽  
The Right

Pleuropulmonary blastomas (PPB) are rare aggressive paediatric lung malignancies associated withDICER1variants. We present two cases, a 2-year-old girl with upper respiratory tract symptoms as well as a 6-month-old girl sibling undergoing screening due to family history of malignancy. Imaging of the 2-year-old girl revealed a large mass filling the right hemithorax which was determined to be a type II PPB after pathological examination. Imaging of the 6-month-old sibling demonstrated a small cystic lesion in the posterior basal segment of the right lower lobe which was determined to be a type 1r PPB after pathological examination. The 2-year-old girl received adjuvant chemotherapy while the baby sister underwent resection alone and both are alive and well at 12 months and 7 months, respectively. Sequence analysis in both cases confirmed the sameDICER1variation, c.2437-2A>G (likely pathogenic), which has not been previously described in the literature.

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