scholarly journals Low-Grade Fibromyxoid Sarcoma of the Lateral Skull Base: Presentation of Two Cases

2019 ◽  
Vol 2019 ◽  
pp. 1-6
Author(s):  
Evgenia Chetverikova ◽  
Priit Kasenõmm
Keyword(s):  
Malignant Tumour ◽  
Low Grade ◽  
Loss Of Consciousness ◽  
First Case ◽  
Clinical Presentations ◽  
Lateral Skull Base ◽  
Fibromyxoid Sarcoma ◽  
Gag Reflex ◽  
The Right ◽  
Slow Growing

Low-grade fibromyxoid sarcoma (LGFMS) is a rare slow-growing malignant tumour with a deceptively benign histologic appearance. Herein, we report two cases of LGFMS with variable clinical presentations. The first case was a 17-year-old female who referred to our department due to deaf ear on the right together with ipsilateral gag reflex impairment and globus sensation in the pharynx. The second case was a 35-year-old female with recurrent LGFMS, suffering from headaches, vertigo, and episodes of loss of consciousness. LGFMS of the temporal bone is a rare pathology, and to the best of our knowledge, no such cases have been reported before.

Disrupting the right pars opercularis with electrical stimulation frees the song: case report

2015 ◽  
Vol 123 (6) ◽  
pp. 1401-1404 ◽  
Author(s):  
Guillaume Herbet ◽  
Gilles Lafargue ◽  
Fabien Almairac ◽  
Sylvie Moritz-Gasser ◽  
François Bonnetblanc ◽  
...  
Keyword(s):  
Language Production ◽  
Inferior Frontal Gyrus ◽  
Awake Surgery ◽  
Low Grade ◽  
Speech Impairment ◽  
First Case ◽  
Pars Opercularis ◽  
The Right

The authors report the first case of a strikingly unusual speech impairment evoked by intraoperative electrostimulation in a 36-year-old right-handed patient, a well-trained singer, who underwent awake surgery for a right fronto-temporo-insular low-grade glioma. Functionally disrupting the pars opercularis of the right inferior frontal gyrus led the patient to automatically switch from a speaking to a singing mode of language production. Given the central role of the right pars opercularis in the inhibitory control network, the authors propose that this finding may be interpreted as possible evidence for a competitive and independent neurocognitive subnetwork devoted to the melodically intoned articulation of words (normal language-based vs singing-based) in subjects with high expertise. From a more clinical perspective, such data may have implications for awake neurosurgery, especially to preserve the quality of life for singers.

scholarly journals Brainstem auditory evoked potentials after irradiation of nasopharyngeal carcinoma—Report on two cases with myelopathy of the brainstem

1988 ◽  
Vol 102 (12) ◽  
pp. 1142-1146 ◽  
Author(s):  
S. K. Lau ◽  
W. I. Wei ◽  
D. Choyt ◽  
J. S. T. Sham ◽  
U. C. G. Engzell
Keyword(s):  
Nasopharyngeal Carcinoma ◽  
Evoked Potentials ◽  
Auditory Evoked Potentials ◽  
Brainstem Auditory Evoked Potentials ◽  
Post Irradiation ◽  
First Case ◽  
Gag Reflex ◽  
Latency Interval ◽  
The Right ◽  
Unilateral Vocal Cord Paralysis

abstractBrainstem auditory evoked potentials (BAEP) were recorded in two patients with nasopharyngeal carcinoma (NPC) irradiated 14 and three years ago respectively and compared with 15 healthy controls. The patients had features of post- irradiation myelopathy of the brainstem with reduced gag reflex, unilateral vocal cord paralysis and fasciculation of the tongue. The first patient had a blind left eye. The second patient had quadriparesis. All ears revealed post-irradiation otitis media changes and mixed deafness. BAEP was not recognizable in the left ear of the first patient and was normal in the left ear of the second patient. Simultaneous electrocochleogram and BAEP were recorded from the right ear of the first case. The wave I–V latency interval were rolonged in both right ears. In the absence of local recurrence and brain secondaries, these BAEP changes are attributed to the post-irradiation myelopathy of brainstem.

scholarly journals Mesothelioma in two sheep with pericardial effusion and ascites

2020 ◽  
Vol 8 (1) ◽  
pp. e001031
Author(s):  
Nicola Fletcher ◽  
Camilla Brena ◽  
Amanda Carson ◽  
Mark Wessels ◽  
Tobias Floyd
Keyword(s):  
Differential Diagnosis ◽  
Pericardial Effusion ◽  
Domestic Animals ◽  
Diagnostic Pathology ◽  
First Case ◽  
Clinical Presentations ◽  
Rare Tumours ◽  
Microscopic Features ◽  
History Of ◽  
The Right

Mesotheliomas are rare tumours in domestic animals. These tumours have a range of clinical presentations, and a range of gross and microscopic features can be present. We report mesotheliomas in two sheep submitted to Animal and Plant Health Agency’s diagnostic pathology service with diverse clinical presentations. The first case was a 2-year-old ewe with a history of sudden death that had a nodular mass in the wall of the right auricle and marked pericardial effusion and ascites. The second case was a 3-year-old ewe with a history of recumbency which had a papillary mass in the peritoneal cavity and marked ascites. A diagnosis of mesothelioma in both cases was confirmed by immunohistochemistry for cytokeratin and vimentin. These cases highlight the diverse presenting signs that can be present with mesothelioma, and this tumour should be considered as a differential diagnosis in sheep with peritoneal, pericardial or pleural effusion at gross postmortem.

scholarly journals A Low-Grade Fibromyxoid Sarcoma of the Internal Abdominal Oblique Muscle

2016 ◽  
Vol 2016 ◽  
pp. 1-4
Author(s):  
Masakazu Hashimoto ◽  
Kei Koide ◽  
Michinori Arita ◽  
Koji Kawaguchi ◽  
Yoshihiro Mikuriya ◽  
...  
Keyword(s):  
Radical Resection ◽  
Oblique Muscle ◽  
Low Grade ◽  
First Case ◽  
Positron Emission ◽  
Muc4 Expression ◽  
Highly Sensitive ◽  
Fibromyxoid Sarcoma ◽  
Fluorine 18 Fluorodeoxyglucose

A low-grade fibromyxoid sarcoma (LGFMS) is a rare tumor, with a benign histologic appearance but malignant behavior. This report describes a 74-year-old man with an internal abdominal oblique muscle mass. The tumor appeared as a well-defined ovoid mass on computed tomography, with mild uptake on fluorine-18-fluorodeoxyglucose positron-emission tomography images. Radical resection with wide safe margins was performed. Histologically, the tumor was composed of spindle-shaped cells in a whorled growth pattern, with alternating fibrous and myxoid stroma. MUC4 expression, a highly sensitive and specific immunohistochemical marker for LGFMS, was detected. Therefore, we diagnosed the tumor as LGFMS. At the 3-month follow-up, there was no sign of recurrence or metastasis. We report the first case of LGFMS arising from the internal abdominal oblique muscle.

scholarly journals Gigantinė retroperitoninio tarpo lipoma: klinikinis atvejis ir literatūros apžvalga

2012 ◽  
Vol 10 (1-2) ◽  
pp. 0-0
Author(s):  
Edgaras Kulikauskas ◽  
Eligijus Poškus ◽  
Dileta Rutkauskaitė ◽  
Kęstutis Strupas
Keyword(s):  
Large Mass ◽  
University Hospital ◽  
Pathological Examination ◽  
Low Grade ◽  
Vilnius University ◽  
Grade Malignancy ◽  
The Right ◽  
E Mail ◽  
Slow Growing ◽  
Primary Retroperitoneal

Edgaras Kulikauskas1, Eligijus Poškus1, Dileta Rutkauskaitė2, Kęstutis Strupas1 1Vilniaus universiteto ligoninės Santariškių klinikų Gastroenterologijos, nefrologijos, urologijos ir abdominalinės chirurgijos klinika, Santariškių g. 2, LT-08661 Vilnius2Vilniaus universiteto Medicinos fakulteto Krūtinės ligų, alergologijos ir radiologijos klinika, Santariškių g. 2, LT-08661 Vilnius El. paštas: [email protected] Pirminiai retroperitoniniai navikai yra reti, pasižymintys didele histologine įvairove. Apie 80 proc. pirminių retroperitoninio tarpo navikų yra piktybiniai, o gerybinės lipomos šioje vietoje aptinkamos labai retai. Augdamos lėtai lipomos gali pasiekti 20 cm dydį ir kelių kilogramų svorį, nesukeldamos ryškesnės simptomatikos. Šių nepiktybinių navikų diagnostika remiasi radiologiniais tyrimais. Atskirti lipomas nuo piktybinių riebalinių navikų, ypač geros diferenciacijos liposarkomomis, kurios retai metastazuoja, tačiau pasižymi dideliu recidyvų dažnumu, gali būti labai sudėtinga. Dėl šių priežasčių riebaliniai retroperitoninio tarpo navikai turi būti vertinami kaip liposarkomos, kol neįrodoma kitaip. Radikalus chirurginis naviko pašalinimas yra pirmiausia pasirenkamas gydymo metodas.Pateikiame klinikinį retroperitoninės lipomos, nustatytos 61 metų amžiaus vyrui, gydymo atvejį. Navikas diagnozuotas remiantis klinika ir kompiuterinės tomografijos tyrimu. Operacijos metu rasta ir pašalinta 40 × 40 × 20 cm dydžio, 6500 g svorio lipoma, diagnozė patvirtinta histologinio tyrimo metu. Devintą parą po operacijos, ligonis išrašytas į namus. Reikšminiai žodžiai: retroperitoninis tarpas, lipoma, chirurgija. Giant retroperitoneal lipoma: case report and literature review Edgaras Kulikauskas1, Eligijus Poškus1, Dileta Rutkauskaitė2, Kęstutis Strupas1 1Clinic of Gastroenterology, Urology and Abdominal Surgery, Vilnius University Hospital “Santariškių klinikos”, Santariškių Str. 2, LT-08661 Vilnius, Lithuania2Vilnius University, Medical Faculty, Clinic of Chest Diseases, Allergology and Radiology, Santariškių Str. 2, LT-08661 Vilnius, Lithuania E-mail: [email protected] Primary retroperitoneal tumours are rare and show a high histological variety. About 80% of retroperitoneal tumours are malignant; benign lipomas in this location are exceptionally rare. These slow-growing tumors can grow up to more than 20 cm and weight a few kilograms. The differential diagnosis of lipomas with liposarcomas may be problematic, especially for tumours with low-grade malignancy, which have a predilection for local recurrence but do not generally metastatize. Fatty tumours of the retroperitoneum should be considered to be potential liposarcomas until proven otherwise, and a radical lesion excision should always be performed, if possible.We report a case of a giant retroperitoneal lipoma in a 61-year-old male. A CT scan of his abdomen showed a large mass of fat density displacing organs to the right side. The patient underwent a radical tumour excision. Laparotomy showed a giant fatty mass measuring 40 x 40 x 20 cm and weighing 6500 g. The pathological examination revealed benign lipoma. The patient was discharged home on postoperative day 9. Key words: retroperitoneal space, lipoma, surgery

scholarly journals Primary Malignant Neuroendocrine Tumour of Pleura: First Case Report

2016 ◽  
Vol 2016 ◽  
pp. 1-5
Author(s):  
Anirban Das ◽  
Abhishek Pratap
Keyword(s):  
Pleural Effusion ◽  
Neuroendocrine Tumour ◽  
Malignant Tumour ◽  
Malignant Neoplasms ◽  
Malignant Tumours ◽  
Correct Treatment ◽  
Prognostic Assessment ◽  
First Case ◽  
Clinical Presentations ◽  
Diffuse Malignant Mesothelioma

Metastatic tumours of pleura are the most common malignant tumours causing malignant pleural effusion. Lungs are the most common primary sites. Primary pleural tumours are rarely seen and diffuse malignant mesothelioma is the most common malignant tumour of pleura. Primary malignant neuroendocrine tumour of pleura is not reported in the literature. Here, we report a rare case of primary malignant neuroendocrine tumour of pleura in a fifty-two-year-old, nonsmoker female who presented with right-sided pleural effusion and ipsilateral, dull aching chest pain. Clinical presentations of inflammatory lesions like tuberculous pleuritis and benign and malignant neoplasms of pleura are indistinguishable; hence, fluid cytology, pleural biopsy, and immunohistochemistry are necessary for exact tissue diagnosis of the tumours, which is mandatory for correct treatment and prognostic assessment.

Manifestations of Pediatric Appendicopathia Oxyurica

2013 ◽  
Vol 79 (9) ◽  
pp. 873-874 ◽  
Author(s):  
Mary M. Jordan ◽  
Jennifer E. Sanders ◽  
Christina R. Stallworth ◽  
Scott Russell ◽  
Olivia Titus ◽  
...  
Keyword(s):  
Abdominal Pain ◽  
Acute Appendicitis ◽  
Ex Vivo ◽  
Low Grade ◽  
Enterobius Vermicularis ◽  
Lower Quadrant ◽  
First Case ◽  
Human Digestive Tract ◽  
The Right ◽  
Right Lower Quadrant

Enterobius vermicularis is a parasite that inhabits the human digestive tract. We present two pediatric patients with symptoms mimicking acute appendicitis who were found to have E. vermicularis infection. The first case is a 5-year-old female who presented with flank and abdominal pain associated with low-grade fever and anorexia. She had localized tenderness in the right lower quadrant and a leukocytosis with left shift. Intraoperative findings included a normal-appearing appendix, but ex vivo examination revealed Enterobius vermicularis. The second case is a 7-year-old female who presented with periumbilical abdominal pain, anorexia, and emesis. She had tenderness at McBurney's point, and ultrasound revealed a small echogenic focus within the appendix. Intraoperatively, the distal tip of the appendix appeared inflamed. Again, ex vivo examination revealed E. vermicularis. Enterobius vermicularis infection of the appendix can present with a clinical picture similar to acute appendicitis. In at-risk populations, it should be included in the differential diagnosis for children with right lower quadrant abdominal pain. Complete therapy requires treatment with mebendazole.

scholarly journals Legal Aspects In Stroke Management

2017 ◽  
pp. 54
Author(s):  
Reza Hajmanouchehri
Keyword(s):  
Initial Dose ◽  
Legal Aspects ◽  
Pain Patient ◽  
Loss Of Consciousness ◽  
Speech Impairment ◽  
Blurred Vision ◽  
Presumptive Diagnosis ◽  
First Case ◽  
Intravenous Heparin ◽  
The Right

Due to increasing the cases of complaint from therapeutic staff, referred to Legal Medicine decided to mention a few examples of these actions and by reviewing them, we want to do something even nothing to prevention. Three cases were given and discussed in this article. 1. Patient is a 68-year-old woman complaining of weakness of her left side and speech disturbance that started about 2 hours earlier, was admitted to hospital at 8 am. Patient with a diagnosis of ischemic stroke in progress is placed in antiplatelet therapy (Plavix 4 initial dose and one per day and an 80 mg aspirin per day) and anti-Coagulation Heparin (initial dose of 6000 units and 1000 units per hour).Patient conflicts with loss of consciousness at 17:45. By doing CT, they have found a large hemorrhage in the right parietal Frontó with severe shift from midline, IVH, SAH. Currently, patient has movement disorders and several cerebral complications. 2. The patient took under angiography because of chest pain. Patient had an unpleasant feeling in organs at the time of angiography and the symptoms have been intensified in the afternoon of that day and conflicted with headache and blurred vision. The next day, he also afflicted with weakness of organs and at 8 am neurology consultation is requested, and according to a neurologist takes MRI. The patient was suffered from speech impairment and right hemiparesis. MRI indicates stroke. Two days later, intravenous heparin begins. The Patient discharged on 31/4/ … . 3. The patient hospitalized because of headache and weakness of right organs and with a presumptive diagnosis of stroke. Headache had progressive trend. There were not seen certain lesions on the initial CT. 5000 units of heparin with 1000 units of infusion in an hour starts with telephone orders at 8 am. The morning 1/8 /..., he afflicted with loss of consciousness, and transferred to the ICU. In morning experiment, patient’s platelet is reported low (47000).The patient gave MRI that had large ischemic lesions of temporoparietal on left with suspicious regions of bleeding and Parietal. Due to low level of platelets (35,000), despite high clinical suspicion for CVST heparin was closed at 11:30. HIT is confirmed in blood consultation and recommended to be cut the anticoagulants. Despite the measures taken, the patient died at 3:45 pm. In first case, it seems that to start double antiplatelet and intravenous heparin simultaneously was wrong. In the second case, late neurology consultation is a question, though heparin is started too late. But in the third case, progression of the disease has been quite rapid.

scholarly journals Radiation-Induced Low Grade Fibromyxoid Sarcoma of the Larynx: a Case Report and Literature Review

Folia Medica ◽  
2021 ◽  
Vol 63 (3) ◽  
pp. 433-437
Author(s):  
Dariya Chivchibashi ◽  
Pavel Pavlov ◽  
Maria Tzaneva ◽  
Nikolay Sapundzhiev ◽  
Georgi Davidov
Keyword(s):  
Case Report ◽  
Latency Period ◽  
Metastatic Potential ◽  
Low Grade ◽  
Imaging Evaluation ◽  
First Case ◽  
Fibromyxoid Sarcoma ◽  
History Of ◽  
Radiation Induced ◽  
Causes And Risk Factors

Low grade fibromyxoid sarcoma (LGFMS) is an uncommon variant of fibrosarcoma with high risk of local recurrence, immense metastatic potential and frequently protracted period between tumour presentation and metastasis. This unusual malignancy rarely affects the region of the head and neck which makes cases of laryngeal LGFMS extremely infrequent. To date, LGFMS of the larynx has been scatteredly mentioned in the literature. Neither incidence nor causes and risk factors for laryngeal LGFMS have been clarified so far. To the authors’ knowledge, this is the first case report that discusses the clinical course, imaging diagnosis, histopathological evaluation and surgical approach to radiation-induced laryngeal LGFMS.We present a case of a 70-year-old man who developed a LGFMS after previous radiotherapy (RT) for squamous cell carcinoma (SCC) of the larynx. The latency period between the time of radiation exposure and the diagnosis of LGFMS was twenty-seven months. After re-confirming the diagnosis with second biopsy and extensive imaging evaluation the patient was subjected to an open partial resection of the larynx. Owing to the rarity of the tumour, there is no established protocol with follow-up recommendations.This case highlights the importance of considering the RT history of the patient in order to monitor radiotherapy-related complications, including the occurrence of LGFMS.

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