Three-dimensional Dielectrophoresis with Dielectric Pillar Arrays Fabricated by Soft Lithography

2015 ◽  
Vol 135 (9) ◽  
pp. 548-552
Author(s):  
Ryo Watabe ◽  
Satoshi Uchida ◽  
Hiroyuki Nishikawa
2021 ◽  
Vol 321 ◽  
pp. 01014
Author(s):  
Makoto Sugimoto ◽  
Tatsuya Miyazaki ◽  
Zelin Li ◽  
Masayuki Kaneda ◽  
Kazuhiko Suga

Stator coils of automobiles in operation generate heat and are cooled by a coolant poured from above. Since the behavior characteristic of the coolant poured on the coils is not clarified yet due to its complexity, the three-dimensional two-phase flow simulation is conducted. In this study, as a steppingstone to the simulation of the liquid falling on the actual coils, the coils are modelled with horizontal rectangular pillar arrays whose governing parameters can be easily changed. The two-phase flows are simulated using the lattice Boltzmann method and the phase-field model, and the effects of the governing parameters, such as the physical properties of the cooling liquid, the wettability, and the gap between the pillars, on the wetting area are investigated. The results show that the oil tends to spread across the pillars because of its high viscosity. Moreover, the liquid spreads quickly when the contact angle is small. In the case that the pillars are stacked, the wetting area of the inner pillars is larger than that of the exposed pillars.


2019 ◽  
Vol 3 (1) ◽  
pp. 26 ◽  
Author(s):  
Mohamed Mohamed ◽  
Hitendra Kumar ◽  
Zongjie Wang ◽  
Nicholas Martin ◽  
Barry Mills ◽  
...  

With the dramatic increment of complexity, more microfluidic devices require 3D structures, such as multi-depth and -layer channels. The traditional multi-step photolithography is time-consuming and labor-intensive and also requires precise alignment during the fabrication of microfluidic devices. Here, we present an inexpensive, single-step, and rapid fabrication method for multi-depth microfluidic devices using a high-resolution liquid crystal display (LCD) stereolithographic (SLA) three-dimensional (3D) printing system. With the pixel size down to 47.25 μm, the feature resolutions in the horizontal and vertical directions are 150 μm and 50 μm, respectively. The multi-depth molds were successfully printed at the same time and the multi-depth features were transferred properly to the polydimethylsiloxane (PDMS) having multi-depth channels via soft lithography. A flow-focusing droplet generator with a multi-depth channel was fabricated using the presented 3D printing method. Experimental results show that the multi-depth channel could manipulate the morphology and size of droplets, which is desired for many engineering applications. Taken together, LCD SLA 3D printing is an excellent alternative method to the multi-step photolithography for the fabrication of multi-depth microfluidic devices. Taking the advantages of its controllability, cost-effectiveness, and acceptable resolution, LCD SLA 3D printing can have a great potential to fabricate 3D microfluidic devices.


Author(s):  
Yichao Yang ◽  
Zhili Hao

This paper reports on a microfluidic-based tactile sensor capable of detecting forces along two directions and torque about one direction. The 3-Degree-Of-Freedom (3-DOF) force/torque sensor encompasses a symmetric three-dimensional (3D) microstructure embedded with two sets of electrolyte-enabled distributed resistive transducers underneath. The 3D microstructure is built into a rectangular block with a loading-bump on its top and two microchannels at its bottom. Together with electrode pairs distributed along the microchannel length, electrolyte in each microchannel functions as a set of three resistive transducers. While a normal force results in a resistance increase in the two sets of transducers, a shear force causes opposite resistance changes in the two sets of transducers. Conversely, a torque leads to the opposite resistance changes in the two side transducers in each set. Soft lithography and CNC molding are combined to fabricate a prototype tactile sensor. The experimental results validate the feasibility of using this microfluidic-based tactile sensor for 3-DOF force/torque detection.


RSC Advances ◽  
2016 ◽  
Vol 6 (114) ◽  
pp. 113344-113351 ◽  
Author(s):  
Chia-Wen Tsao ◽  
Xu-Cheng Guo ◽  
Wei-Wen Hu

We create an elastic porous polydimethylsiloxane highly stretchable conductive substrate. The surface is fabricated by a simple soft lithography process that replicates the 3D corrugated porous microstructures from a low-cost commercially available abrasive paper.


Langmuir ◽  
1999 ◽  
Vol 15 (3) ◽  
pp. 826-836 ◽  
Author(s):  
Rebecca J. Jackman ◽  
Scott T. Brittain ◽  
Allan Adams ◽  
Hongkai Wu ◽  
Mara G. Prentiss ◽  
...  

2020 ◽  
Vol 7 (3) ◽  
pp. 102 ◽  
Author(s):  
Emily Cady ◽  
Jacob A. Orkwis ◽  
Rachel Weaver ◽  
Lia Conlin ◽  
Nicolas N. Madigan ◽  
...  

Bioactive surfaces and materials have displayed great potential in a variety of tissue engineering applications but often struggle to completely emulate complex bodily systems. The extracellular matrix (ECM) is a crucial, bioactive component in all tissues and has recently been identified as a potential solution to be utilized in combination with biomaterials. In tissue engineering, the ECM can be utilized in a variety of applications by employing the biochemical and biomechanical cues that are crucial to regenerative processes. However, viable solutions for maintaining the dimensionality, spatial orientation, and protein composition of a naturally cell-secreted ECM remain challenging in tissue engineering. Therefore, this work used soft lithography to create micropatterned polydimethylsiloxane (PDMS) substrates of a three-dimensional nature to control cell adhesion and alignment. Cells aligned on the micropatterned PDMS, secreted and assembled an ECM, and were decellularized to produce an aligned matrix biomaterial. The cells seeded onto the decellularized, patterned ECM showed a high degree of alignment and migration along the patterns compared to controls. This work begins to lay the groundwork for elucidating the immense potential of a natural, cell-secreted ECM for directing cell function and offers further guidance for the incorporation of natural, bioactive components for emerging tissue engineering technologies.


Author(s):  
M. Wettergreen ◽  
J. Scheffe ◽  
A. G. Mikos ◽  
M. A. K. Liebschner

The goal of this study was to develop an efficient and repeatable process for fabrication of micro-particles from multiple materials using rapid prototyping and soft lithography. Phase change three-dimensional printing was used to create masters for PDMS molds. A photocrosslinkable polymer was then delivered into these molds to fabricate geometrically complex three-dimensional micro-particles. This repeatable process has demonstrated the ability to generate micro-particles with greater than 95% repeatability with complete pattern transfer. This process was illustrated for three shapes based on the extrusion of two-dimensional shapes. These particles will allow for tailoring of the pore shapes within a porous scaffold utilized in tissue engineering applications. In addition, the different shapes may allow control of drug release by varying the surface to volume ratio, which could modulate drug delivery. While soft lithography is currently used with photolithography, its high precision is offset by high cost of production. The employment of rapid prototyping to a specific resolution offers a much less expensive alternative with increased throughput due to the speed of current rapid prototyping systems.


2006 ◽  
Vol 88 (18) ◽  
pp. 181112 ◽  
Author(s):  
Jae-Hwang Lee ◽  
Chang-Hwan Kim ◽  
Yong-Sung Kim ◽  
Kai-Ming Ho ◽  
Kristen Constant ◽  
...  

Lab on a Chip ◽  
2014 ◽  
Vol 14 (7) ◽  
pp. 1294-1301 ◽  
Author(s):  
Anthony K. Au ◽  
Wonjae Lee ◽  
Albert Folch

We explore the three-dimensional capabilities, resolution, and optical clarity of microfluidic devices fabricated by stereolithography using a mail-order service, and we compare the cost and prototyping speed of soft lithography with those of stereolithography.


MRS Bulletin ◽  
2001 ◽  
Vol 26 (7) ◽  
pp. 523-528 ◽  
Author(s):  
J. Christopher Love ◽  
Janelle R. Anderson ◽  
George M. Whitesides

Two-dimensional (2D) methods for transferring patterns to planar substrates have enabled the technological revolution in microfabrication that has marked the last 40 years. The overall trend toward increased miniaturization has led to the development of new types of devices in areas unrelated to conventional microelectronics: analytical tools, chemical reactors, microelectromechanical systems (MEMS), optical systems, and sensors. The widespread use and high level of technological development associated with photolithography has also made the methodologies for microelectronics—patterning photosensitive polymers, etching and deposition of thin films, and liftoff—ubiquitous in the fabrication of these new classes of microsystems. These new systems have specialized requirements, however, and are not simple extensions of microelectronics technologies. They often require materials—especially organic polymers—that are not commonly used in microelectronic systems, they must have low cost, and they may need 3D structures in order to implement complex designs. These requirements have stimulated the development of new methods for microfabrication.


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