Rising Vancomycin-Resistant Enterococcus Infections in Hospitalized Children in the United States

2016 ◽  
Vol 6 (7) ◽  
pp. 404-411 ◽  
Author(s):  
Daniel J. Adams ◽  
Matthew D. Eberly ◽  
Anthony Goudie ◽  
Cade M. Nylund
2001 ◽  
Vol 67 (10) ◽  
pp. 4930-4933 ◽  
Author(s):  
Valerie J. Harwood ◽  
Miriam Brownell ◽  
William Perusek ◽  
John E. Whitlock

ABSTRACT Vancomycin-resistant Enterococcus spp. (VRE) were isolated from sewage and chicken feces but not from other animal fecal sources (dog, cow, and pig) or from surface waters tested. VRE from hospital wastewater were resistant to ≥20 μg of vancomycin/ml and possessed the vanA gene. VRE from residential wastewater and chicken feces were resistant to 3 to 5 μg of vancomycin/ml and possessed the vanC gene.


2009 ◽  
Vol 30 (2) ◽  
pp. 184-186 ◽  
Author(s):  
Andrew M. Ramsey ◽  
Marya D. Zilberberg

Although the incidence of hospitalizations with infection due to vancomycin-resistant pathogens in the United States remained stable during 2000–2003, it increased from 4.60 to 9.48 hospitalizations per 100,000 population during 2003–2006. Hospitalizations with infection due to vancomycin-resistant pathogens also increased as a proportion of all US hospitalizations, from 3.16 to 6.51 hospitalizations with VRE infection per 10,000 total hospitalizations during 2003–2006. The number of hospitalizations with infection due to vancomycin-resistant pathogens is increasing in the United States. Because infection due to vancomycin-resistant organisms is associated with poor outcomes, the epidemiology of this trend needs further exploration.


Author(s):  
Cecilia G. Carvalhaes ◽  
Helio S. Sader ◽  
Jennifer M. Streit ◽  
Mariana Castanheira ◽  
Rodrigo E. Mendes

Oritavancin displayed potent and stable activity (MIC 90 range, 0.06-0.5 mg/L) over time (2010-2019) against Gram-positive pathogens causing bloodstream infections, including methicillin-resistant Staphylococcus aureus and resistant subsets of Enterococcus spp. Daptomycin and linezolid were also active against methicillin-resistant S. aureus and vancomycin-resistant Enterococcus . Only oritavancin and linezolid remained active against Enterococcus faecium isolates displaying an elevated daptomycin MIC (i.e., 2-4 mg/L). Proportions of methicillin-resistant S. aureus and vancomycin-resistant Enterococcus within the respective S. aureus and enterococcal populations decreased over this period.


2018 ◽  
Vol 57 (5) ◽  
pp. 534-541 ◽  
Author(s):  
Kevin J Downes ◽  
Darcy Ellis ◽  
Sondra Lavigne ◽  
Matthew Bryan ◽  
Theoklis E Zaoutis ◽  
...  

2018 ◽  
Vol 2 (12) ◽  
pp. 1403-1408 ◽  
Author(s):  
Shannon L. Carpenter ◽  
Troy Richardson ◽  
Matt Hall

Key Points Rates of pediatric PE in hospitalized patients increased 184% from 2001 to 2014. Mortality as a result of PE in children has decreased over time and is now comparable to that from VTE.


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