PULMONARY AGENESIS

PEDIATRICS ◽  
1955 ◽  
Vol 15 (6) ◽  
pp. 761-767
Author(s):  
Harriette Clark ◽  
Roland B. Scott ◽  
John B. Johnson

Two cases of agenesis of the lung, both with anomalies of the urinary tract, have been presented. In 1 patient the diagnosis was made at post-mortem examination at the age of 5 weeks. Associated anomalies in this patient included defect of the interatrial septum, anomalous drainage of the pulmonary vein into the right atrium, and congenital bilateral ureterovesicle obstruction with dilatation of the ureters and kidney pelves. In the second patient, the diagnosis was made at the age of 3 years. A follow-up study 12 years later substantiated the diagnosis and revealed pelvic location of fused kidneys with short ureters bilaterally. In the latter case, the lung anomaly has not resulted in any dysfunction of the heart or pulmonary circulation. There has been some decrease in ventilatory function but not sufficiently severe to result in respiratory symptoms. This patient is living and well at the time of this report.

2016 ◽  
Vol 32 (12) ◽  
pp. 2002-2008 ◽  
Author(s):  
Mohamed El-Helaly ◽  
Hanan H Balkhy ◽  
Khan Waseem ◽  
Sahdia Khawaja

Previous cross-sectional studies have shown that exposure to cleaning chemicals among health-care workers (HCWs) is associated with respiratory disorders and ventilatory function changes. This study aimed to further explore this association using a longitudinal approach. A prospective 2-year follow-up study was carried out at a tertiary care hospital in Saudi Arabia from June 2012 to June 2014 among 56 nurses who were responsible for disinfection and sterilization of medical instruments and equipment. The workplaces of the participants were assessed for engineering, environmental, and safety control measures. Self-administered questionnaires were distributed to all participants to assess their exposure to cleaning chemicals and their medical history. Spirometric parameters were measured for all nurses in 2012 (baseline) and again in 2014 (follow-up). The prevalence of work-related respiratory symptoms did not increase significantly over this time. Among all the spirometric parameters, only forced expiratory volume in 1 second (FEV1)/forced vital capacity (FVC) ratio decreased significantly, and only 10.7% of participants who were exposed to cleaning chemicals for more than 10 years had FEV1 and FVC less than their longitudinal normal limits at the end of the study. Smoking and gender were associated with statistically significant decreases in some of the spirometric parameters. Our 2-year follow-up study did not demonstrate significant association between exposure to cleaning chemicals among HCWs and changes in the prevalence of work-related respiratory symptoms, but indicated early effects on ventilatory function among them. The study highlights the importance of periodic spirometry, proper work practices, and effective control measures to protect HCWs against potentially harmful workplace chemicals for disinfection and sterilization.


2020 ◽  
Vol 9 (8) ◽  
pp. 4292
Author(s):  
Manisha Bisht ◽  
PreetinderSingh Manshahia ◽  
Ankur Mittal ◽  
Mohit Bhatia ◽  
ShailendraS Handu

Indoor Air ◽  
1997 ◽  
Vol 7 (4) ◽  
pp. 262-268 ◽  
Author(s):  
Outi M. Koskinen ◽  
Tuula M. Husman ◽  
Anne M. Hyvarinen ◽  
Tiina A. Reponen ◽  
Aino I. Nevalainen

2013 ◽  
Vol 12 (1) ◽  
Author(s):  
Yong Cai ◽  
Rong Shi ◽  
Huijiang Song ◽  
Meili Shang ◽  
Tian Shen ◽  
...  

2016 ◽  
Vol 81 (1-2) ◽  
Author(s):  
Federica Ciccarese ◽  
Giorgio Garzillo ◽  
Anna Maria Chiesa ◽  
Antonio Poerio ◽  
Serena Baroncini ◽  
...  

<p>Bronchial diverticula have been described as a common radiological finding in smoker patients with COPD, but the specificity of this sign should be further investigated. Thus, the aim of our study was to evaluate the prevalence of diverticula in a cohort of non-smoker subjects. Between February and July 2012, 2438 patients were admitted to our Radiology Unit to undergo a chest CT. Among them, we enrolled 121 non-smoking patients (78/121-64.5% females, 43/121-35.5% males), of different age (57.0±20.7 years-range: 12-88), without any respiratory symptoms, submitted to chest CT for several reasons (oncologic evaluation: 59/121-48.8%; follow up of lung nodules: 27/121-22.3%; screening in connectivitis: 12/121-9.9%; others: 23/121-19.0%). We considered thin-section CT scan on axial, coronal and sagittal plans to evaluate prevalence, numbers and level of bronchial diverticula. Diverticula were found in 41/121-33.9% patients, with a slight major prevalence in males (p=0.048), but no significant difference on age. In 31/41-75.6% the number was &lt;3, whereof 17/31-54.8% with just one diverticulum assessed. Regarding the level, in 30/41-73.2% they were subcarinal, but they were also detected in mainstem (2/41-4.9%) and lobar bronchi (with the right upper lobe bronchus most frequently involved- 12/41-29.3%). Bronchial diverticula can be observed in non-smokers, as well as in smoker patients with COPD. However, their prevalence seems to be lower than in smokers and they tend to be isolated and subcarinal. The age of patients does not influence their finding. More studies should be proposed to better define a cut-off between smokers and healthy subjects.</p>


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