scholarly journals Novel Imaging Techniques for Heart Failure

2016 ◽  
Vol 2 (1) ◽  
pp. 27 ◽  
Author(s):  
Josep L Melero-Ferrer ◽  
Raquel López-Vilella ◽  
Herminio Morillas-Climent ◽  
Jorge Sanz-Sánchez ◽  
Ignacio J Sánchez-Lázaro ◽  
...  

Imaging techniques play a main role in heart failure (HF) diagnosis, assessment of aetiology and treatment guidance. Echocardiography is the method of choice for its availability, cost and it provides most of the information required for the management and follow up of HF patients. Other non-invasive cardiac imaging modalities, such as cardiovascular magnetic resonance (CMR), nuclear imaging-positron emission tomography (PET) and single-photon emission computed tomography (SPECT) and computed tomography (CT) could provide additional aetiological, prognostic and therapeutic information, especially in selected populations. This article reviews current indications and possible future applications of imaging modalities to improve the management of HF patients.

2019 ◽  
Vol 2019 ◽  
pp. 1-12 ◽  
Author(s):  
Han Feng ◽  
Xiaobo Wang ◽  
Jian Chen ◽  
Jing Cui ◽  
Tang Gao ◽  
...  

Glucose homeostasis plays a key role in numerous fundamental aspects of life, and its dysregulation is associated with many important diseases such as cancer. The atypical glucose metabolic phenomenon, known as the Warburg effect, has been recognized as a hallmark of cancer and serves as a promising target for tumor specific imaging. At present, 2-deoxy-2-[18F]fluoro-glucose (18F-FDG)-based positron emission tomography/computed tomography (PET/CT) represented the state-of-the-art radionuclide imaging technique for this purpose. The powerful impact of 18F-FDG has prompted intensive research efforts into other glucose-based radiopharmaceuticals for positron emission tomography (PET) and single-photon emission computed tomography (SPECT) imaging. Currently, glucose and its analogues have been labeled with various radionuclides such as 99mTc, 111In, 18F, 68Ga, and 64Cu and have been successfully investigated for tumor metabolic imaging in many preclinical studies. Moreover, 99mTc-ECDG has advanced into its early clinical trials and brings a new era of tumor imaging beyond 18F-FDG. In this review, preclinical and early clinical development of glucose-based radiopharmaceuticals for tumor metabolic imaging will be summarized.


2006 ◽  
Vol 16 (06) ◽  
pp. 1671-1687 ◽  
Author(s):  
A. S. FOKAS ◽  
V. MARINAKIS

The imaging techniques of magnetoencephalography (MEG), computed tomography (CT), positron emission tomography (PET) and single photon emission computed tomography (SPECT) are reviewed, and the analytical solutions of the relevant inverse problems are presented. The numerical implementation of the exact formulas yield accurate reconstructions for both realistic phantoms as well as real data.


2019 ◽  
Vol 65 (3) ◽  
Author(s):  
Hanna Piwowarska-Bilska ◽  
Aleksandra Supińska ◽  
Jacek Iwanowski ◽  
Adriana Tyczyńska ◽  
Bożena Birkenfeld

Positron emission tomography (PET) is currently the most advanced diagnostic imaging technology along with well-known techniques like magnetic resonance imaging (MRI) and computed tomography (CT). Tremendous technical progress in engineering, imaging and radiopharmacy has provided the basis for impressive technological advances in the field of nuclear medicine over the past 50 years. Current nuclear medicine can be divided into 2 groups: the classic, which uses gamma-cameras for single photon emission computed tomography (SPECT) imaging, and the more modern PET technique. The clinical PET technique requires: (i) patient administration of the radiopharmaceutical labelled with a positron emitter, (ii) recording of the gamma radiation emitted from the patient’s body with a dedicated PET/ CT scanner, (iii) processing and analysis of recorded images. This article presents the basics of PET technology and research, and describes new technical trends introduced by the leading manufacturers of PET/CT scanners.


Author(s):  
Allison C. Nugent ◽  
Maura L. Furey

Neuroscience research has clearly demonstrated neurological correlates of psychological disorders. We believe that neuroscience, particularly neuroimaging, has great potential to increase our understanding of these disorders, leading to more effective treatments, prevention, and perhaps even cure. Nevertheless, the popular media is replete with misinformation and exaggerated claims. The present chapter is intended to give the reader the necessary knowledge to critically evaluate neuroimaging studies of psychological disorders. We provide an overview of all the major neuroimaging techniques, example studies relevant to psychological disorders (with a particular emphasis on depression), particular pitfalls and caveats associated with each technique, and the promise of each technique. We first cover the nuclear imaging techniques, single photon emission computed tomography (SPECT) and positron emission tomography (PET). We then explore several magnetic resonance imaging (MRI) techniques, both structural and functional. Finally, we give an overview of the electrophysiological techniques, electroencephalography (EEG) and magnetoencephalography (MEG). Each of these techniques has particular strengths, and particular weaknesses. At this point, none of these tools are diagnostic, but each one provides a unique window into psychological disorders. When applied in a methodologically rigorous and statistically rigorous manner, neuroimaging has great promise for achieving greater understanding of psychological disorders, and relieving the great burdens they cause.


Author(s):  
Malgorzata Solnik ◽  
Natalia Paduszynska ◽  
Anna M. Czarnecka ◽  
Kamil J. Synoradzki ◽  
Yacoub A. Yousef ◽  
...  

Uveal melanoma is the most common primary intraocular malignancy in adults characterized by insidious onset and poor prognosis strongly associated with tumor size and the presence of distant metastases, most commonly in the liver. Contrary to most tumor identification, biopsy followed by pathological exam is not recommended in ophthalmic oncology. Therefore, early and non-invasive diagnosis is essential to enhance patients’ chances for early treatment possibilities. We reviewed imaging modalities currently used in the diagnosis of uveal melanoma, i.e., fundus imaging, ultrasonography (US), optical coherence tomography (OCT), single-photon emission computed tomography (SPECT), positron emission tomography/computed tomography (PET/CT), magnetic resonance imaging (MRI), fundus fluorescein angiography (FFA), indocyanine green angiography (ICGA), fundus autofluorescence (FAF). The principle of imaging techniques was briefly explained, along with their role in the diagnostic process and a summary of their advantages and limitations. Further, the experimental data and the advancements in imaging modalities were searched. We described their innovations, showed current usage and research, and explained the possibilities of utilizing them to diagnose uveal melanoma and their potential application in personalized medicine such as theranostics.


2015 ◽  
Vol 3 (2) ◽  
pp. 38
Author(s):  
Sahithi Dathar ◽  
Sudhakara Reddy ◽  
Jyothirmai Koneru ◽  
M Preethi ◽  
Satheesh Guvvala

<p>Nuclear imaging is an exceptional branch of medical science that has been evolved in the latest decades in early diagnosis of a disease. The main underlying principle is that radioisotopes are injected in the body and emits gamma rays which are detected by special image receptors. Various nuclear imaging modalities include Scintigraphy, SPECT (Single photon emission computed tomography) and PET (Positron emission tomography) which can assess any functional changes that occur within a diseased cell. This article has essentially dealt with the fundamental principles of various nuclear imaging modalities and their applications in oral and maxillofacial region.</p>


2020 ◽  
Vol 26 (10) ◽  
pp. 1470-1484 ◽  
Author(s):  
Mariane Le Fur ◽  
Iris Y Zhou ◽  
Onofrio Catalano ◽  
Peter Caravan

Abstract Inflammatory bowel disease (IBD) is defined by a chronic relapsing and remitting inflammation of the gastrointestinal tract, with intestinal fibrosis being a major complication. The etiology of IBD remains unknown, but it is thought to arise from a dysregulated and excessive immune response to gut luminal microbes triggered by genetic and environmental factors. To date, IBD has no cure, and treatments are currently directed at relieving symptoms and treating inflammation. The current diagnostic of IBD relies on endoscopy, which is invasive and does not provide information on the presence of extraluminal complications and molecular aspect of the disease. Cross-sectional imaging modalities such as computed tomography enterography (CTE), magnetic resonance enterography (MRE), positron emission tomography (PET), single photon emission computed tomography (SPECT), and hybrid modalities have demonstrated high accuracy for the diagnosis of IBD and can provide both functional and morphological information when combined with the use of molecular imaging probes. This review presents the state-of-the-art imaging techniques and molecular imaging approaches in the field of IBD and points out future directions that could help improve our understanding of IBD pathological processes, along with the development of efficient treatments.


Syntax Idea ◽  
2021 ◽  
Vol 3 (12) ◽  
pp. 2564
Author(s):  
Esther Devina Panjaitan ◽  
Hendra Budiawan

Bone is the most common site to which breast cancer metastasizes and sometimes is the first affected site in a substantial proportion of women with advanced breast cancer. A lot of study has highlighted that imaging modalities visualize different aspects of osseous tissues (cortex or marrow). Imaging bone metastases is problematic because the lesions can be osteolytic, osteoblastic, or mixed, and imaging modalities are based on either direct anatomic visualization of the bone or tumor or indirect measurements of bone or tumor metabolism. Bone imaging by skeletal scintigraphy can be an essential part, and positron emission tomography or single-photon emission computed tomography have a potential of evaluating bone metastases, but no consensus exists as to the best modality for diagnosing the lesion and for assessing its response to treatment. In this review, we discuss the use of each nuclear imaging for bone modality for diagnosing bone metastases from breast cancer


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