scholarly journals Tumor venéreo transmisible canino de presentación atípica

Author(s):  
Rodrigo Crossley ◽  
Johana Alejandra Ramírez

An 8 years old, intact male, boxer was presented at the Santo Tomas Veterinary Teaching Hospital because of a volume increase in his right eye of 2 months of duration; which didn´t respond to oral prednisone (0,7 mg/kg, BID), or dexamethasone and tobramycin in ophthalmic ointment (1 drop, TID). On physical exam, a mass in the third eyelid and another on the base of the penis were noted. Cytology of the mass near the genital area showed cells compatible with transmissible venereal tumor (TVT). Besides that, ocular ultrasonography showed an irregular mass with neoplastic characteristics in the medial area of the eyeball and abdominal ultrasound indicated a mass dorsal to the bladder. Fine needle aspiration of the eye and abdomen masses were done under sedation; cytology of the tumor in the abdomen indicated TVT and in the eye the results were suppurative inflammation, necrosis and epithelial dysplasia. Neoplasia couldn´t  be rule out or confirmed. Initial treatment included vincristine (8 cycles, 0,7 mg/m²) obtaining a parcial remission; so considering a possible resistance of the cells to this drug, doxorrubicin (30 mg/m²) was used. The patient had a positive response to doxorrubicin achieving complete remission with a single aplication.

2021 ◽  
Vol 7 (2) ◽  
pp. 205511692110528
Author(s):  
Kelsey Renner ◽  
Sarah Hill ◽  
Alex Grinberg ◽  
Amy Weeden

Case summary An 11-year-old female spayed Maine Coon cat was referred for assessment of hyporexia, weight loss, vomiting and diarrhoea. An abdominal ultrasound revealed an enlarged and hypoechoic pancreas containing two large fluid-filled structures. Fine-needle aspiration of the cyst-like structures was performed, and cytology revealed moderate-to-marked predominantly suppurative inflammation with yeast cells. Candida glabrata was cultured from the fluid. The patient was treated with oral itraconazole and the clinical signs resolved, although repeat abdominal ultrasound and cytology revealed persistence of the infected cyst-like structures. The patient remained asymptomatic for 8 months after the discontinuation of antifungal medications, despite the persistence of the pancreatic infection with C glabrata. Relevance and novel information To our knowledge, this is the first report of pancreatic infection with Candida species in a cat, followed by a chronic subclinical infection persisting for at least 8 months after treatment discontinuation.


Respiration ◽  
2021 ◽  
pp. 1-4
Author(s):  
Nikhil Meena ◽  
Thaddeus Bartter ◽  
Roshen Mathew ◽  
Abhishek Kumar ◽  
Winnie Elma Roy ◽  
...  

<b><i>Background:</i></b> Rapid on-site cytologic evaluation (ROSE) is not always available for fine needle aspiration (FNA) specimens. We have examined the relationships between the presence of “GOOP” (defined as gooey white material) on FNA aspirates, on-site adequacy (OSA), and diagnosis. <b><i>Methods:</i></b> Consecutive FNA samples obtained over the study interval were included. Samples were assessed macroscopically for the presence or absence of GOOP (GOOP+ or GOOP−). GOOP+ samples were further characterized as shiny (G+<sub>S</sub>) or cheesy (G+<sub>C</sub>). Gross descriptors were correlated with OSA and final diagnoses. <b><i>Results:</i></b> Of the 204 sites biopsied, 102 were malignant, 94 benign, and 8 nondiagnostic. The presence of GOOP was highly predictive for adequacy (positive predictive value 98%). While these correlations for GOOP positivity were significant, the absence of GOOP did not rule out adequacy or malignancy. The presence of GOOP was also significantly correlated with a malignant diagnosis. <b><i>Conclusions:</i></b> We have prospectively demonstrated that the presence of GOOP correlates strongly with adequacy. This may be of value for those for whom ROSE is not available and, when available, may help prioritize specimens for on-site review.


2018 ◽  
Vol 31 (1) ◽  
pp. 133-136 ◽  
Author(s):  
Bérengère Dequéant ◽  
Quentin Pascal ◽  
Héloïse Bilbault ◽  
Elie Dagher ◽  
Maria-Laura Boschiroli ◽  
...  

A 6-y-old neutered male ferret ( Mustela putorius furo) was presented because of a 1-mo history of progressive weight loss, chronic cough, and hair loss. On clinical examination, the animal was coughing, slightly depressed, moderately hypothermic, and had bilateral epiphora. Thoracic radiography was suggestive of severe multinodular interstitial pneumonia. Abdominal ultrasound examination revealed hepatosplenomegaly and mesenteric and pancreaticoduodenal lymphadenopathy. Fine-needle aspiration of the pancreaticoduodenal lymph node, followed by routine Romanowsky and Ziehl–Neelsen stains, revealed numerous macrophages containing myriad acid-fast bacilli, leading to identification of mycobacteriosis. Autopsy and histologic examination confirmed the presence of disseminated, poorly defined, acid-fast, bacilli-rich granulomas in the pancreaticoduodenal and mesenteric lymph nodes, intestines, and lungs. Destaining of May-Grünwald/Giemsa–stained slides with alcohol, and then restaining with Ziehl–Neelsen, revealed acid-fast rods and avoided repeat tissue sampling without affecting the Ziehl–Neelsen stain quality and cytologic features. Tissue samples were submitted for a PCR assay targeting the heat shock protein gene ( hsp65) and revealed 100% homology with Mycobacterium genavense. We emphasize the use of special stains and PCR for identification of this potential zoonotic agent.


2019 ◽  
Vol 7 (2) ◽  
pp. e000841
Author(s):  
Garrett Fraess ◽  
Ryan Dickinson ◽  
Brandy Kragness ◽  
Miranda Sadar

A 31-year-old, 5.01 kg, intact male black-capped capuchin (Sapajus apella) was presented for examination after zookeepers noted an enlarged right testicle. Fine-needle aspiration with cytological evaluation identified a seminoma of the right testis. Castration was elected for this non-breeding male, and both testicles were submitted for histopathology. Histopathology confirmed the presence of a seminoma in the right testicle and, incidentally, a mass in the left testis consistent with an interstitial cell tumour was also diagnosed. This report describes the first case of seminoma or interstitial cell neoplasia in a black-capped capuchin, as well as the first case of a non-human primate with synchronous, bilateral testicular neoplasms.


2020 ◽  
Vol 08 (01) ◽  
pp. E25-E28
Author(s):  
J. D. Ulrich ◽  
K. Specht ◽  
A. M. Schlitter ◽  
G. O. Ceyhan ◽  
M. Quante ◽  
...  

AbstractA 49-year-old woman consulted her general practitioner (GP) regarding epigastric pain that she had experienced for 2 months. Physical examination and laboratory results were unremarkable. An abdominal ultrasound indicated a solid pancreatic tumor, which was confirmed on subsequent CT and MRI. Endoscopic ultrasound (EUS) showed a well-defined heterogeneous, predominantly hypoechoic mass in the pancreatic body, so a neuroendocrine tumor (NET) was suspected. However, EUS-guided fine-needle aspiration (EUS-FNA) was performed and based on (immuno-)histochemical findings, the extremely rare diagnosis of a perivascular epithelioid cell tumor (PEComa) of the pancreas was made. Due to the malignant potential of pancreatic PEComas, laparoscopic left-sided pancreatectomy was performed. We present a case diagnosed by preoperative EUS-FNA highlighting the clinical and endosonographic features which help to distinguish it from its most important differential diagnosis, neuroendocrine tumors (NETs) of the pancreas.


2019 ◽  
Vol 12 (7) ◽  
pp. e230645 ◽  
Author(s):  
Albert John Bromeo ◽  
Armida Suller

A 3-year-old woman presented with a large ulcerated lesion involving the left upper eyelid and left earlobe with erythematous, swollen, undermined and advancing borders. Culture of the ulcer showed no growth of organisms. Treatment with empiric intravenous and topical antibiotics showed no improvement. Workup revealed an elevated white blood cell count with elevated neutrophil count, elevated erythrocyte sedimentation rate and C reactive protein and positive antinuclear antibody. A skin biopsy showed a neutrophilic dermatitis with vasculitis. The patient was started on oral prednisone, which resulted in halting of the progression of ulceration and clinically decreased skin inflammation. The skin biopsy and positive response to corticosteroids confirmed the diagnosis of pyoderma gangrenosum. Pyoderma gangrenosum is a rare inflammatory skin condition and rarely presents as lesions of the eyelid. Early initiation of immunosuppressive therapy prevents disfigurement. Eyelid reconstruction in these cases may prove to be difficult.


2017 ◽  
Vol 53 (5) ◽  
pp. 281-284 ◽  
Author(s):  
Rebecca Laube ◽  
Alysa Cook ◽  
Kevin Winkler

ABSTRACT An 8 mo old intact male mixed-breed dog presented for diphallia with paraphimosis of the nonfunctional, accessory penis. Bloodwork, an abdominal ultrasound, and a positive contrast retrograde urethrogram were performed and revealed no other structural abnormalities. Surgical excision of the accessory penis was elected. This is one of three reported cases of diphallia in the dog in the English literature, but this is the only case in which no other congenital abnormalities were identified. The authors also review diphallia in both the veterinary and human literature.


2017 ◽  
Vol 36 (11) ◽  
pp. 2237-2244 ◽  
Author(s):  
Mitsuru Sugimoto ◽  
Tadayuki Takagi ◽  
Rei Suzuki ◽  
Naoki Konno ◽  
Hiroyuki Asama ◽  
...  

2017 ◽  
Vol 10 (1) ◽  
pp. 301-307 ◽  
Author(s):  
Mari Mizuno ◽  
Yoshiaki Kawaguchi ◽  
Aya Kawanishi ◽  
Yohei Kawashima ◽  
Atsuko Maruno ◽  
...  

A 45-year-old woman was found to have a pancreatic tumor by abdominal ultrasound performed for a medical check-up. Abdominal contrast-enhanced computed tomography showed a hypovascular tumor measuring 30 mm in diameter in the pancreatic tail. Endoscopic ultrasound-guided fine needle aspiration was performed. An extragastric growing gastrointestinal stromal tumor was thereby diagnosed preoperatively, and surgical resection was planned. Laparoscopic surgery was attempted but conversion to open surgery was necessitated by extensive adhesions, and distal pancreatectomy, splenectomy, and partial gastrectomy were performed. The histological diagnosis was an intra-abdominal desmoid tumor. A desmoid tumor is a fibrous soft tissue tumor arising in the fascia and musculoaponeurotic tissues. It usually occurs in the extremities and abdominal wall, and only rarely in the abdominal cavity. We experienced a case with an intra-abdominal desmoid tumor that was histologically diagnosed after laparotomy, which had been preoperatively diagnosed as an extragastric growing gastrointestinal stromal tumor. Although rare, desmoid tumors should be considered in the differential diagnosis of intra-abdominal tumors. Herein, we report this case with a literature review.


2014 ◽  
Vol 2014 ◽  
pp. 1-4
Author(s):  
Carlos Eduardo Fonseca-Alves ◽  
Aline Gonçalves Corrêa ◽  
Fabiana Elias ◽  
Sabryna Gouveia Calazans

A 10-year-old, intact male, pinscher was presented with unilateral bloodstained nasal discharge, sneezing, dyspnea, zygomatic arch deformity, submandibular lymph node increase, blindness in right eye, and exophthalmia. After clinical examination, it was found that the animal presented with upper respiratory tract dyspnea origin, possibly caused by an obstructive process. Complete blood count (CBC), ocular ultrasonography, thoracic radiographs, mandibular lymph node, and nasal sinus fine needle aspiration were performed. The right mandibular lymph node excisional biopsy was conducted and a tumor sample was obtained through the nasal fistula at hard palate. The material was processed, paraffin embedded, sectioned, and stained with hematoxylin and eosin. Immunohistochemical staining for cytokeratin (AE1/AE3), vimentin, and COX-2 was performed. After histopathological evaluation nasal carcinoma diagnosis was obtained. Chemotherapy was established with carboplatin 300 mg/m2intravenously—four cycles with intervals of 21 days—and firocoxib 5 mg/kg orally every 24 hours for 7 months. After 7 months the treatment started, the animal presented with ataxia, vocalization, hyperesthesia, and anorexia. Due the clinical condition presented, the animal owner opted for performing euthanasia. The chemotherapy protocol was effective causing the disease stagnation, minimizing the clinical signs, and extending patient survival and quality of life.


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