scholarly journals Limitations of serum albumin level as a marker of nutritional status in hemodialysis patients

2020 ◽  
Vol 9 (1) ◽  
pp. 149
Author(s):  
Lucky Aziza Abdullah Bawazir
Keyword(s):  
Nutritional Status ◽  
Serum Albumin ◽  
Serum Albumin Level ◽  
Hemodialysis Patients ◽  
Albumin Level

Nutritional Status of the Children with Acute Lymphoblastic Leukemia at Diagnosis and after Completion of Induction

2021 ◽  
Vol 5 (02) ◽  
pp. 50-56
Author(s):  
Noor-A-Sabah Liza ◽  
S. M. Rezanur Rahman ◽  
Afiqul Islam ◽  
Chowdhury Yakub Jamal ◽  
Mohosina Sultana Setu ◽  
...  
Keyword(s):  
Nutritional Status ◽  
Serum Albumin ◽  
Induction Chemotherapy ◽  
Induction Therapy ◽  
Serum Albumin Level ◽  
Albumin Level ◽  
Anthropometric Measurements ◽  
Newly Diagnosed ◽  
Significant Difference ◽  
Nutritional Status Of Children

Background: Adequate nutrition is an important concern in children with leukemia. Malnutrition and weight lost are common and are due to verity of mechanism involving the tumor, the host response to the tumor such as infection and pharmacokinetics of chemotherapeutic drugs. Objective: To evaluate and compare the nutritional status of children with ALL at diagnosis and after completion of induction therapy. Methodology: This prospective observational study included 60 children newly diagnosed as ALL, aged 2-15 years, over a period from April 2012 to September 2012 in the Department of Pediatric Hematology and Oncology, BSMMU. The anthropometric measurements and serum albumin level were taken. Anthropometric indices are calculated by NCHS (WHO-2000) and classified as Z score. Children <-2 SD are considered as underweight (WFA), stunted (HFA) and wasted (WFH). Serum albumin level below 21g/dl is considered as severely malnourished. The Hb values of the children are compared with normal values by age. The children got induction chemotherapy according to MRC-11 protocol. They were in regular follow up and again anthropometric measurements and serum albumin level were taken after completion of induction. Results: Out of 60 children with ALL, 48 (70%) were underweight, 45 (75%) were stunted 36 (60%) were wasted at diagnosis. Incidence of malnutrition among leukemia children after completion of induction were 24 (40%) underweight, 45 (75%) were stunted and 6 (10%) were wasted. The results showed that children in the newly diagnosed stage had a higher prevalence of malnutrition. However no statistically significant difference in the nutritional status was found among newly diagnosed and after completion of induction in term of underweight and stunting but newly diagnosed patients had statistically significant wasting than patients who had completed induction chemotherapy. No patient showed severe malnutrition based on the cut-off point for serum albumin on both stages. All the children (100%) had less than normal range hemoglobin levels. Conclusion: Malnutrition was higher in children with newly diagnosed leukemia. Children had significant differences in the nutritional status in term of wasting at diagnosis than after completion of induction therapy. So, the nutritional status of children with leukemia should be monitor periodically.

scholarly journals Aortic Arch Calcification as a Predictor of Repeated Arteriovenous Fistula Failure within 1-Year in Hemodialysis Patients

2017 ◽  
Vol 2017 ◽  
pp. 1-9
Author(s):  
Yit-Sheung Yap ◽  
Kai-Ting Ting ◽  
Wen-Che Chi ◽  
Cheng-Hao Lin ◽  
Yi-Chun Liu ◽  
...  
Keyword(s):  
Serum Albumin ◽  
Arteriovenous Fistula ◽  
Aortic Arch ◽  
Serum Albumin Level ◽  
Binary Logistic Regression ◽  
Hemodialysis Patients ◽  
Albumin Level ◽  
Binary Logistic Regression Analysis ◽  
The Impact ◽  
Aortic Arch Calcification

Objectives. The aim of the study was to identify the factors associated with repeated arteriovenous fistula (AVF) failure within 1-year, especially the impact of aortic arch calcification (AAC) on patency of AVF.Materials and Methods. We retrospectively assessed chest radiography in hemodialysis patients who had undergone initial AVF. The extent of AAC was categorized into four grades (0–3). The association between AAC grade, other clinical variables, and repeated failure of AVF was then analyzed by binary logistic regression analysis.Results. This study included 284 patients (158 males, mean age61.7±13.1years). Patients with higher AAC grade were older, had more frequently diabetes mellitus and cardiovascular disease, had lower diastolic blood pressure, and had higher corrected calcium and lower intact parathyroid hormone levels. In multivariate analysis, the presence of higher AAC grade (odds ratio (95% confidence interval): 2.98 (1.43–6.23);p=0.004), lower mean corrected calcium (p=0.017), and mean serum albumin level (p=0.008) were associated with repeated failure of AVF.Conclusions. The presence of higher AAC grade, lower mean corrected calcium and mean serum albumin level were independently associated with repeated AVF failure within 1 year in hemodialysis patients.

Impact of Nutritional Status on Peritonitis in CAPD Patients

2007 ◽  
Vol 27 (1) ◽  
pp. 42-47 ◽  
Author(s):  
Narayan Prasad ◽  
Amit Gupta ◽  
Raj K. Sharma ◽  
Archna Sinha ◽  
Ramesh Kumar
Keyword(s):  
Nutritional Status ◽  
Serum Albumin ◽  
Serum Albumin Level ◽  
Risk Index ◽  
Univariate Analysis ◽  
Albumin Level ◽  
Calorie Intake ◽  
Cox Regression Analysis ◽  
Nutritional Risk Index ◽  
The Impact

Objective To determine the impact of nutritional status on peritonitis in patients on continuous ambulatory peritoneal dialysis (CAPD) in a developing country. Methods 56 patients with end-stage renal disease on CAPD were randomly selected for this study. These patients were assessed for nutritional status and peritonitis episodes. Nutritional parameters were assessed by anthropometry, diet, body mass index (BMI), Nutritional Risk Index (NRI), serum albumin level, and Subjective Global Assessment (SGA). Based on SGA, patients were categorized into either group 1 (malnutrition, n = 31) or group 2 (normal nutritional status, n = 25). Peritonitis was considered the primary outcome and was compared between the two groups. Results Demographic profiles, Kt/V, creatinine clearance, and mean follow-up of the two groups were similar. Number of peritonitis episodes was significantly higher in patients with malnutrition (25/31) compared to patients with normal nutritional status (4/25) ( p = 0.001). Mean peritonitis rate per patient per year was also significantly higher in patients with malnutrition (0.99 ± 1.07) compared to patients with normal nutritional status (0.18 ± 0.42) ( p = 0.007). On univariate analysis, malnutrition based on SGA ( p = 0.009), NRI ( p = 0.02), serum albumin level ( p = 0.005), and calorie intake ( p = 0.006) was a significant predictor of peritonitis. On multivariate Cox regression analysis, only SGA ( p = 0.001, odds ratio 0.08, 95% confidence interval 0.02 – 0.36) was found to be a significant predictor of peritonitis. On general linear model, the observed power of prediction of peritonitis was 0.96 based on SGA. On Kaplan–Meier survival analysis, peritonitis-free survival in patients with normal nutrition (42 months) was significantly higher compared to patients with malnutrition (21 months) based on SGA (log rank p = 0.003). Conclusion We conclude that peritonitis rate is high in patients with malnutrition and that malnutrition indices, especially SGA, can predict the peritonitis rate in CAPD patients.

scholarly journals Association of a high normalized protein catabolic rate and low serum albumin level with carpal tunnel syndrome in hemodialysis patients

Medicine ◽  
2016 ◽  
Vol 95 (26) ◽  
pp. e4050 ◽  
Author(s):  
Wen-Hung Huang ◽  
Ching-Wei Hsu ◽  
Cheng-Hao Weng ◽  
Tzung-Hai Yen ◽  
Jui-Hsiang Lin ◽  
...  
Keyword(s):  
Carpal Tunnel Syndrome ◽  
Serum Albumin ◽  
Carpal Tunnel ◽  
Serum Albumin Level ◽  
Hemodialysis Patients ◽  
Albumin Level ◽  
Catabolic Rate ◽  
Tunnel Syndrome ◽  
Protein Catabolic Rate ◽  
Low Serum

scholarly journals Improved serum albumin level by a polyacrilonitrile membrane in diabetic hemodialysis patients.

1997 ◽  
Vol 30 (11) ◽  
pp. 1289-1293
Author(s):  
Yoshihiro Matsumoto ◽  
Joji Ono ◽  
Ken Sakai ◽  
Sonoo Mizuiri ◽  
Akira Hasegawa
Keyword(s):  
Serum Albumin ◽  
Serum Albumin Level ◽  
Hemodialysis Patients ◽  
Albumin Level

Evaluation of Nutritional Status and Factors Related to Malnutrition in Children on CAPD

2003 ◽  
Vol 23 (6) ◽  
pp. 557-562 ◽  
Author(s):  
Mesiha Ekim ◽  
Aydan Ikinciogullari ◽  
Betul Ulukol ◽  
Sevcan A. Bakkaloglu ◽  
Nuray Ozkaya ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Standard Deviation ◽  
Nutritional Status ◽  
Serum Albumin ◽  
Significant Positive Correlation ◽  
Serum Albumin Level ◽  
Standard Deviation Score ◽  
Albumin Level ◽  
Upper Arm ◽  
Positive Correlations

Objective The aim of this study was to investigate the nutritional status of children on continuous ambulatory peritoneal dialysis (CAPD) and to relate it to the dose of dialysis and serum levels of inflammatory cytokines and insulin-like growth factor-1 (IGF-1). Patients 17 CAPD patients (8 girls, 9 boys; mean age 13.1 ± 3.5 years, median 15 years) were included in the study. Anthropometric measurements and serum albumin levels were used in the evaluation of nutritional status. Serum interleukin (IL)-1β, IL-6, tumor necrosis factor α, and IGF-1 levels were determined in all CAPD patients and in a healthy control group. Weekly Kt/V and creatinine clearance (CCr) were measured to determine adequacy of dialysis. Results The mean dialysis period was 23.7 ± 15.2 months (median 23 months). Anthropometric measurements and serum albumin level were as follows: height 130.2 ± 15.6 cm, height standard deviation score (HtSDS) -4.2 ± 2.4, body mass index (BMI) 16.3 ± 1.6 kg/m2, body mass index standard deviation score (BMISDS) -0.8 ± 0.9, triceps skinfold thickness (TST) 4.2 ± 1.4 mm, midarm circumference (MAC) 16.21 ± 2.3 cm, upper arm muscle area (AMA) 1799.1 ± 535.7 mm2, upper arm fat area (AFA) 334.5 ± 143 mm2, and serum albumin 3.1 ± 0.7 g/dL. The BMI was above the fifth percentile in all patients; TST and MAC were below the fifth percentile in 14 patients (82.4%) and 10 patients (58.8%) respectively. The AMA was below the fifth percentile in 8 patients; however, the AFA was below the fifth percentile in all patients. Mean serum albumin level was under 3.5 g/dL in 70.5% of the children. We found significant positive correlations between BMI and Kt/V ( r = 0.69, p < 0.01), CCr ( r = 0.64, p < 0.05), and IL-6 ( r = 0.61, p < 0.01). There was an inverse correlation between BMISDS and dialysis period ( r = -0.58, p < 0.05); and between IL-6 and serum albumin ( r = -0.49, p < 0.05). A significant positive correlation between BMISDS and serum IGF-1 level ( r = 0.62, p < 0.01) was noted. We also found a significant positive correlation between serum IGF-1 level and both HtSDS ( r = 0.57, p < 0.05) and TST ( r = 0.52, p < 0.05). Significant positive correlations between AFA and CCr and IGF-1 were also noted (both r = 0.56, p < 0.05). Conclusion Although many factors may be responsible for malnutrition and growth retardation, we found that prolonged period of dialysis, inadequate dialysis, and low IGF-1 levels are the most important risk factors in CAPD patients.

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