scholarly journals Clinical presentation and outcome of COVID-19 infection in Type 2 Diabetes Mellitus: a preliminary data from a tertiary hospital in Jakarta during the early days of the pandemic

2020 ◽  
Vol 9 (3) ◽  
pp. 787
Author(s):  
Ida Ayu Kshanti ◽  
Giri Aji ◽  
Marina Epriliawati ◽  
Md Ikhsan Mokoagow ◽  
Jerry Nasarudin ◽  
...  
2021 ◽  
Vol 19 (3) ◽  
pp. 122-125
Author(s):  
Rohit Chordia ◽  

Background: Comorbidities are important events in the natural history of the disease and have a negative effect on the morbidity and mortality of COPD patients. It is increasingly recognized that, many patients with COPD have co-morbidities that have a major impact on quality of life and survival. Present study aims at studying the prevalence and effects of comorbidities in COPD patients at a tertiary hospital. Material and Methods: Present study was cross sectional, observational study conducted in COPD patients, diagnosed for more than 5 years, underwent investigations for various comorbidities. Results: In present study, 130 COPD patients were studied for various co-morbidities. Majority of cases were from 50 -64 years age group (49.23 %) and were male (97.69 %). Smoking was major factor noted among cases (73.85 %), out of them 23.96 % were current smoker. Mean duration since quitting of smoking was 7.24 ± 5.83 years. Comorbidities noted in present study were systemic hypertension (42.31 %), GERD and gastric ulceration (31.54 %), type 2 diabetes mellitus (30.77 %), metabolic syndrome (29.23 %), anemia (11.54 %), left sided cardiac abnormalities (10.77 %), depression (8.46 %), obstructive sleep apnea (6.92 %), ischemic heart disease (6.15 %), osteoporosis (4.62 %), bronchiectasis (2.31 %) and lung cancer (0.77 %). Conclusion: Comorbidities noted in present study were hypertension, GERD, type 2 diabetes mellitus, metabolic syndrome, anaemia, left sided cardiac abnormalities and depression.


BMJ Open ◽  
2019 ◽  
Vol 9 (7) ◽  
pp. e029280 ◽  
Author(s):  
Bander Balkhi ◽  
Monira Alwhaibi ◽  
Nasser Alqahtani ◽  
Tariq Alhawassi ◽  
Thamir M Alshammari ◽  
...  

ObjectivesThe purpose of this study is to measure the adherence rates of oral antidiabetic drugs (OADs) in patients with type 2 diabetes mellitus (T2DM) and assess the relationship of glycaemic control and adherence to OADs after controlling for other associated factors.DesignCross-sectional retrospective study.SettingLarge tertiary hospital in the central region of Saudi Arabia.Participants5457patients aged 18 years and older diagnosed with T2DM during the period from 1 January 2016 to 31 December 2016.Primary and secondary outcome measuresThe modified medication possession ratio (mMPR) was calculated as a proxy measure for adherence of OADs. The factors associated with OADs non-adherence and medication oversupply were assessed using multinomial logistic regression models. The secondary outcomes were to measure the association between OADs adherence and glycaemic control.ResultsMajority of patients with T2DM were females (n=3400, 62.3%). The average glycated haemoglobin was 8.2±1.67. Among the study population, 48.6% had good adherence (mMPR >0.8) and 8.6% had a medication oversupply (mMPR >1.2). Good adherence was highest among those using repaglinide (71.0%) followed by pioglitazone (65.0%) and sitagliptin (59.0%). In the multivariate analysis, women with T2DM were more likely to have poor adherence (adjusted OR (AOR)=0.76, 95% CI=0.67, 0.86) compared with men. Also, medication oversupply was more likely among patients with hyperpolypharmacy (AOR=1.88, 95% CI=1.36, 2.63), comorbid osteoarthritis (AOR=1.72, 95% CI=1.20, 02.45) and non-Saudi patients (AOR=1.53, 95% CI=1.16, 2.01). However, no association was found between glycaemic control and adherence to OADs.ConclusionThe study findings support the growing concern of non-adherence to OADs among patients with T2DM in Saudi Arabia. Decision makers have to invest in behavioural interventions that will boost medication adherence rates. This is particularly important in patients with polypharmacy and high burden of comorbid conditions.


2020 ◽  
Vol 11 (1) ◽  
pp. 1-9
Author(s):  
Chizolum Opara Hope ◽  
Nonyem Anarado Agnes ◽  
Juliet Anetekhai Chinenye ◽  
Njideka Iheanacho Peace ◽  
Lewechi Okoronkwo Ijeome ◽  
...  

2016 ◽  
Vol 5 (86) ◽  
pp. 6360-6363
Author(s):  
Aparna Patange ◽  
Shruti Rao ◽  
Paritosh Desai ◽  
Aken Desai ◽  
Dany John ◽  
...  

2020 ◽  
Vol 8 (15) ◽  
pp. 9-15
Author(s):  
Zayda Arlette Trejo Osti ◽  
Jorge Abelardo Falcón Lezama

Despite T2DM is considered a nosological entity of adults, it has increased in children under 19 years old. This is due to changes in lifestyles but above all to the increase of overweight and obesity registered in recent years. There are multiple studies focused on describing both the epidemiology and the clinical presentation of T2DM in children and adolescents. In Mexico, there is little research that provides data on the behavior and distribution of this disease in the Mexican population. However, given the characteristics of the population, it is very likely to find more cases than those that are currently reported. That is why this article aims at making a brief analysis of the main risk factors associated with diabetes, epidemiology, physiopathology, clinical presentation as well as diagnosis and treatment in T2DM in adolescents. 


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