Synthesis and characterization of bimetallic noble metal nanoparticles for biomedical applications

MRS Advances ◽  
2016 ◽  
Vol 1 (11) ◽  
pp. 681-691 ◽  
Author(s):  
Prem C. Pandey ◽  
Govind Pandey
Keyword(s):  
Metal Ions ◽  
Prussian Blue ◽  
Metal Nanoparticles ◽  
Noble Metal ◽  
Time Course ◽  
Bimetallic Nanoparticles ◽  
Reducing Agents ◽  
Noble Metal Nanoparticles ◽  
Ambient Conditions ◽  
Peroxidase Mimetic

ABSTRACTWe report herein a facile approach to synthesize processable bimetallic nanoparticles (Pd-Au/AuPd/Ag-Au/Au-Ag) decorated Prussian blue nanocomposite (PB-AgNP). The presence of cyclohexanone/formaldehyde facilitates the formation of functional bimetallic nanoparticles from 3-aminopropyltrimethoxysilane (3-APTMS) capped desired ratio of hetero noble metal ions. The use of 3-APTMS and cyclohexanone also enables the synthesis of polycrystalline Prussian blue nanoparticles (PBNPs). As synthesized PBNPs, Pd-Au/Au-Pd/Ag-Au/Au-Ag enable the formation of nano-structured composites displaying better catalytic activity than that recorded with natural enzyme. The nanomaterials have been characterized by Uv-Vis, FT-IR and Transmission Electron Microscopy (TEM) with following major findings: (1) 3-APTMS capped noble metal ions in the presence of suitable organic reducing agents i.e.; 3 glycidoxypropyltrimethoxysilane (GPTMS), cyclohexanone and formaldehyde; are converted into respective nanoparticles under ambient conditions, (2) the time course of synthesis and dispersibility of the nanoparticles are found as a function of organic reducing agents, (3) the use of formaldehyde and cyclohexanone in place of GPTMS with 3-APTMS outclasses the other two in imparting better stability of amphiphilic nanoparticles with reduced silanol content, (4) simultaneous synthesis of bimetallic nanoparticles under desired ratio of palladium/gold and silver/ gold cations are recorded, (5) the nanoparticles made from the use of 3-APTMS and cyclohexanone enable the formation of homogeneous nanocomposite with PBNP as peroxidase mimetic representing potential substitute of peroxidase enzyme. The peroxidase mimetic ability has been found to vary as a function of 3-APTMS concentration revealing the potential role of functional metal nanoparticles in bioanalytical applications.

Self-assembled calixarene aligned patterning of noble metal nanoparticles on graphene

Nanoscale ◽  
2014 ◽  
Vol 6 (9) ◽  
pp. 4517-4520 ◽  
Author(s):  
Xianjue Chen ◽  
Kasturi Vimalanathan ◽  
Wenzhe Zang ◽  
Ashley D. Slattery ◽  
Ramiz A. Boulos ◽  
...  
Keyword(s):  
Metal Ions ◽  
Metal Nanoparticles ◽  
Noble Metal ◽  
Phosphonic Acid ◽  
Hydrogen Gas ◽  
Noble Metal Nanoparticles ◽  
Self Assembled

Patterns of noble metal nanoparticles (NMNPs) of ruthenium and platinum are formed on p-phosphonic acid calix[8]arene stabilized graphene in water with hydrogen gas induced reduction of the metal ions.

Role of organic functionalities linked to alkoxysilane precursors in nanomaterials synthesis and their biomedical applications

2015 ◽  
Vol 1719 ◽  
Author(s):  
P. C. Pandey ◽  
Govind Pandey
Keyword(s):  
Salt Tolerance ◽  
Metal Ions ◽  
Metal Nanoparticles ◽  
Noble Metal ◽  
Biomedical Applications ◽  
Ph Sensitivity ◽  
Noble Metal Nanoparticles ◽  
Biological Interactions ◽  
Wide Range

ABSTRACTThe synthesis of biocompatible noble metal nanoparticles dispersible in a wide range of biological media with control of polycrystalinity and nanogeometry, pH sensitivity and salt tolerance has been a challenging requirements. The role of 3-aminopropyltrimethoxysilane (3-APTMS) and organic reducing reagents for real time synthesis of amphilic noble metal nanoparticles meeting these requirements are demonstrated justifying the following; (1) 3-APTMS capped noble metal ions are converted into respective metal nanoparticles in the presence of one of organic reducing agents i.e., cyclohexanone, tetrahydrofuran hydroperoxide (THF-HPO), formaldehyde, acetaldehyde, acetone, t-buty dimethyl keotone, 3-Glycidoxy-propyltrimethoxysilane (3-GPTMS); (2) 3-APTMS acts as micelle, promotes the interaction of metal ions with organic reducing agent, precisely controls the size of metal nanoparticles, pH sensititvity and salt tolerance and also provides a suitable medium for nanoparticles suspension, (3) the use of suitable organic reagent precisely controls the polarity of as made noble metal nanoparticles allowing specific biological interactions, and (4) 3-APTMS significantly increases the stability and controls the pH sensitivity and salt tolerance of metal nanoparticles. The as synthesized nanomaterials show potential viability in biomedical applications from many angles i.e. (a) as potential bioelectrocatalyst, (b) selective interaction with active proteins and cellular components, and (c) peroxidase mimetic.

3-Aminopropyltrimethoxysilane Mediated Controlled Synthesis of Functional Noble Metal Nanoparticles and Its Multi-Metallic Analogues in the Presence of Small Organic Reducing Agents for Selective Application

MRS Advances ◽  
2018 ◽  
Vol 3 (15-16) ◽  
pp. 789-801
Author(s):  
Prem C. Pandey ◽  
Govind Pandey
Keyword(s):  
Metal Nanoparticles ◽  
Noble Metal ◽  
Metallic Nanoparticles ◽  
Present Report ◽  
Reducing Agents ◽  
Noble Metal Nanoparticles ◽  
Practical Significance ◽  
Similar Process ◽  
Controlled Synthesis ◽  
Polarity Index

ABSTRACTSynthesis of functional noble metal nanoparticles (AuNPs, AgNPs, and PdNPs) and its multi-metallic analogues have received greater attentions for selective applications. The selective applications of the these nanoparticles essentially requires the processability of as synthesized nanoparticles in the medium of desired polarity index that manifest the potential exploration of nanomaterial based design in targeted area. The use of conventional reducing and stabilizing agents during routine synthesis of such nanoparticles are not suitable with the system of practical significance and require additional reagents that limit the optimum activity of nanomaterial in targeted design. According there is a challenging issue in the synthesis of noble metal nanoparticles that allow the controlled synthesis of such nanoparticles involving same starting material with option to control the processability of as generated nanomaterial in the system of desired polarity index. The present report is focused on such challenging issues. We have found that 3-aminopropyltrimethoxysilane (3-APTMS) capped noble metal cations can be precisely converted into respective monometallic, bimetallic and trimetallic analogues and can be made processable in water at one end having controlled option to reversed the processability of the same in the toluene as a function of small organic reducing agents. The organic reducing agents not only convert 3-APTMS-capped noble cations into respective nanoparticles but also control the processability of the as generated nanoparticles in the systems of desired polarity index. The similar process also allows the synthesis of function bimetallic and tri-metallic nanoparticles. The role of cyclohexanone, formaldehyde and acetone in the presence of 3-APTMS is reported.

scholarly journals Morphology, Photocatalytic and Antimicrobial Properties of TiO2 Modified with Mono- and Bimetallic Copper, Platinum and Silver Nanoparticles

Nanomaterials ◽  
2019 ◽  
Vol 9 (8) ◽  
pp. 1129 ◽  
Author(s):  
Izabela Wysocka ◽  
Ewa Kowalska ◽  
Jacek Ryl ◽  
Grzegorz Nowaczyk ◽  
Anna Zielińska-Jurek
Keyword(s):  
Photocatalytic Activity ◽  
Metal Nanoparticles ◽  
Noble Metal ◽  
Photoelectron Spectroscopy ◽  
Bimetallic Nanoparticles ◽  
Diffuse Reflectance Spectroscopy ◽  
Action Spectrum ◽  
Noble Metal Nanoparticles ◽  
Biocidal Activity ◽  
X Ray

Noble metal nanoparticles (NMNPs) enhanced TiO2 response and extended its activity under visible light. Photocatalytic activity of TiO2 modified with noble metal nanoparticles strongly depends on the physicochemical properties of NMNPs. Among others, the differences in the size of NMNPs seems to be one of the most important factors. In this view, the effect of the metal’s nanoparticles size, type and amount on TiO2 photocatalytic and biocidal activity was investigated. TiO2 modified with mono- and bimetallic nanoparticles of Pt, Cu and Ag were prepared using chemical and thermal reduction methods. Obtained nanocomposites were characterized using transmission electron microscopy (TEM), X-ray photoelectron spectroscopy (XPS), X-ray diffraction (XRD) and diffuse-reflectance spectroscopy (DR/UV-Vis) techniques. The photocatalytic activity was examined in 2-propanol oxidation and hydrogen generation processes. The mechanism of modified TiO2 excitation was evaluated in action spectrum measurements during phenol oxidation. A possibility of using less energy-consuming light sources as a set of light-emitting diodes (LEDs) selected based on action spectrum results was examined. It was found that the differences in NMNPs size were the result of the reduction method. Moreover, coupling with a second metal strongly affected and differentiated the photocatalytic and biocidal activity of the obtained TiO2-based photocatalysts.

scholarly journals Synthesis and Applications of Processable Prussian Blue Nanoparticles

2020 ◽  
pp. 93-107
Author(s):  
Prem C. Pandey ◽  
Priyanshi Pandey
Keyword(s):  
Heterogeneous Catalysis ◽  
Prussian Blue ◽  
Noble Metal ◽  
Present Report ◽  
Reducing Agents ◽  
Metal Nanoparticle ◽  
Noble Metal Nanoparticles ◽  
Synthetic Approach ◽  
Typical Application ◽  
Prussian Blue Nanoparticles

The present report describes a comparative study on chemical synthesis of processable Prussian blue Nanoparticles (PBNPs) suitable for developing PB-based devices. Controlled nucleation of PBNP from single precursors, Potassium hexacyanoferrate, has been recorded as a function of reducing and stabilizing ability of some active organic reducing agents. The use of organic reagent control the nucleation process yielding PBNPs displaying both homogeneous and heterogeneous catalysis. Four different systems of active organic reducing agents i.e.: (1) 3-aminopropyltrimethoxysilane (3-APTMS) and cyclohexanone, (2) tetrahydrofuran hydroperoxide, (3) tetrahydrofuran and hydrogen peroxide and (4) tetrahydrofuran hydroperoxide and 2-(3, 4-epoxycyclohexyl) ethyltrimethoxysilane resulted the formation of PBNP1, PBNP2, PBNP3 and PBNP4 displaying sensitivity of analysis to the order of 480, 330 350 and 400 mA mM-1 cm-2 respectively.The as reported process also enable the controlled synthesis of noble metal nanoparticles introducing new rout for yielding Prussian blue-noble metal nanoparticle nanocomposite that manipulate the catalytic/elecrocatalytic activity for targeted system. As made PBNPs undergo the formation of homogeneous nanodispersion with gold nanoparticles and ruthenium bipyridyl with gradual enhancement in the catalytic activity. The typical application in probing glucose oxidase catalyzed reaction based on both homogeneous and heterogeneous catalysis has been recorded. In addition the synthetic approach could also be explored to incorporate Prussian blue and palladium nanoparticles in mesoporous matrix for developing variety of PB-based devices.

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