scholarly journals Features of the treatment of secretory evacuation disorders in acute bronchitis in children with impaired respiratory function

2020 ◽  
pp. 52-58
Author(s):  
L.S. Ovcharenko ◽  
◽  
A.A. Vertehel ◽  
T.G. Andrienko ◽  
I.V. Samokhin ◽  
...  
Keyword(s):  
Conflict Of Interest ◽  
Respiratory Function ◽  
Acute Bronchitis ◽  
Ethics Committee ◽  
Key Words Children ◽  
External Respiration ◽  
Minimal Effect ◽  
Good Tolerance ◽  
Helsinki Declaration ◽  
Respiration Function

Objective: to increase the efficiency and safety of the treatment of the bronchi secretory-evacuation disorders in acute bronchitis with impaired respiratory function in children by using a medication with minimal effect on the cardiovascular system. Materials and methods. Under observation were 60 children aged 6 to 11 years. 2 observation groups were formed (30 children in each group): 1st group — children receiving the Bronchipret® for 10 days with acute bronchitis with impaired respiratory function; 2nd group — children who do not receive the Bronchipret in acute bronchitis with impaired respiratory function. Results. In the group of patients taking Bronchipret®, in addition to faster clinical dynamics, according to spirography, there was an improvement in the parameters of the external respiration function, characterizing the obstructive component of the obstruction of the air flow. After therapy with Bronchipret®, normalization of the functioning of the autonomic nervous system and the predominance of eutonia were observed against the background of a decrease in the number of registration of parasympathicotonia. Conclusion. The good tolerance and safety of Bronchipret® during 7-day use in patients aged 6–11 years allows us to recommend this drug as a highly effective treatment for bronchi secretory-evacuation disorders in acute bronchitis in children. The research was carried out in accordance with the principles of the Helsinki Declaration. The study protocol was approved by the Local Ethics Committee of participating institution. The informed consent of the patient was obtained for conducting the studies. No conflict of interest was declared by the authors. Key words: children, bronchitis, spirography, treatment, thyme, ivy.

scholarly journals MUCOACTIVE THERAPY FOR IMPAIRED RESPIRATORY FUNCTION IN CHILDREN WITH ACUTE BRONCHITIS.

2020 ◽  
Vol 47 (4) ◽  
Author(s):  
L. S. Ovcharenko ◽  
A. A. Vertehel ◽  
T. G. Andrienko ◽  
I. V. Samokhin ◽  
A. V. Kryazhev ◽  
...  
Keyword(s):  
Cardiovascular System ◽  
Respiratory Function ◽  
Clinical Symptoms ◽  
Herbal Remedy ◽  
Acute Bronchitis ◽  
External Respiration ◽  
Group Comparison ◽  
Minimal Effect ◽  
Keywords Children ◽  
Objective Indicators

Abstract Mucoactive therapy for impaired respiratory function in children with acute bronchitis Purpose of the study. Increasing the efficiency and safety of therapy of the bronchi secretoryevacuation disorders in acute bronchitis with impaired respiratory function in children by using a medication with minimal effect on the cardiovascular system. Materials and methods. The study included 60 children aged 6 to 11 years, suffering from acute bronchitis for 1–2 days. Formed 2 groups of observation (30 children in each group): 1st group (main) – children receiving phytopreparation for 10 days in the complex therapy of the bronchi secretory-evacuation disorders in acute bronchitis with impaired function of external respiration; 2-nd group (comparison) – children receiving ambroxol. The dynamics of the severity of bronchitis was assessed according to the BSS scale (0–20 points). Results. The clinical symptoms of acute bronchitis according to the BSS scale were significantly faster and more effective in the group of children taking the herbal remedy already on the 4-th day of therapy. In the group of patients taking phytopreparation, there was an improvement in objective indicators of respiratory function according to spirography data. In children of the 1st group, the period of recovery is accompanied by the normalization of indicators of the functioning of the autonomic nervous system and the predominance of eutonia against the background of a decrease in the number of registrations of parasympathicotonia. Conclusions. Treatment of acute bronchitis in children using a phytopreparation normalizes the indices of autonomic regulation and functioning of the cardiovascular system, which contributes to a faster and more effective relief of clinical symptoms with the restoration of the function of external respiration.  Keywords: children, bronchitis, spirography, treatment

scholarly journals Cystoscopic features of the ureteral orifices in children with vesicoureteral reflux

2021 ◽  
pp. 36-42
Author(s):  
R.A. Nakonechnyy ◽  
◽  
A.Y. Nakonechnyi ◽  
Keyword(s):  
Informed Consent ◽  
Vesicoureteral Reflux ◽  
Conflict Of Interest ◽  
Positive Association ◽  
Ethics Committee ◽  
Healthy Children ◽  
Ureteral Orifice ◽  
Bladder Mucosa ◽  
Topographic Characteristics ◽  
Helsinki Declaration

Purpose – to establish cystoscopic prognostic criteria for vesicoureteral reflux (VUR) in children. Materials and methods. Clinical material covers 270 patients with VUR II–IV grades aged 9 months to 14 years and 22 healthy children. The study included patients with VUR in the period of clinical and laboratory remission without symptoms of neurogenic bladder. During cystoscopy, the condition of the bladder mucosa was assessed; location, shape, hydrodistention degree, and ureteral orifices contractility. Results. Patients with VUR were diagnosed ureteral orifices in the form of: horseshoes – 127 (47.04%) patients, stadium – 106 (39.26%) and golf holes – 37 (13.7%). They were in the zones: A – 13 (4.81%) children, B – 154 (57.04%), C – 67 (24.81%), D – 36 (13.33%), and were characterized by the hydrodistention degree: H0 – 7 (2.59%) patients, H1 – 173 (64.07%), H2 – 60 (22.22%) and H3 – 30 (11.11%). In children with VUR, sluggish peristalsis of the ureter orifices clearly prevailed – 252 (93.33%) cases, relative to active peristalsis in only 18 (6.67%) patients. Conclusions. For ureteral orifices in the form of a stadium and with more pronounced signs of deepening, which are shifted to zone B and laterally to the sidewall of the bladder, with a hydrodistention degree above H1 has a positive association with VUR at the highest specificity of tests. Unfavorable prognostic diagnostic markers for effective minimally invasive interventions in patients with VUR should be considered ureteral orifices, which combine such morpho-topographic characteristics as pronounced signs of deepening to the shape of a golf hole, lateralization to the sidewall of the bladder in zone D, and hydrodistention H3 degree. The research was carried out in accordance with the principles of the Helsinki declaration. The study protocol was approved by the Local ethics committee of all participating institution. The informed consent of the patient was obtained for conducting the studies. No conflict of interest was declared by the authors. Key words: vesicoureteral reflux, ureteral orifice, cystoscopy, children.

scholarly journals The role of integrated assessment of the indicators of external respiration function in cardiac surgical patients

2017 ◽  
Vol 89 (9) ◽  
pp. 109-114
Author(s):  
O V Kamenskaja ◽  
A S Klinkova ◽  
I Ju Loginova ◽  
V V Lomivorotov ◽  
D N Ponomarev ◽  
...  
Keyword(s):  
Integrated Assessment ◽  
Pulmonary Ventilation ◽  
Surgical Patients ◽  
External Respiration ◽  
Diffusing Capacity ◽  
Body Plethysmography ◽  
Operational Risks ◽  
Respiration Function

This literature review dedicated to the importance of an integrated assessment of external respiratory function in cardiovascular diseases (CVDs), including an analysis of up-to-date techniques, such as spirometry, body plethysmography, examination of the diffusing capacity of the lung, determination of O2 consumption with evaluation of the effectiveness of pulmonary ventilation. It considers the pathogenetic components of impairments in pulmonary ventilation and gas exchange, which develop in different CVDs, as well as during and after cardiac surgery. The authors analyze the results of international investigations and their own experience, which emphasize the prognostic value of lung function tests and suggest that there is a need for a comprehensive functional assessment of the respiratory system in cardiac surgical patients for their effective preoperative preparation, assessment and reduction of operational risks, and improvement of the prognosis of surgical treatment.

External respiration function in children with atopic dermatitis

1998 ◽  
Vol 79 (4) ◽  
pp. 282-285
Author(s):  
A. M. Potemkin ◽  
T. V. Klykova ◽  
I. A. Blonde
Keyword(s):  
Risk Factors ◽  
Atopic Dermatitis ◽  
Bronchial Asthma ◽  
Preventive Measures ◽  
External Respiration ◽  
Respiration Function

The data on the frequency of revealing the bronchial permeability disorders are presented and the mechanisms of its development in children with atopic dermatitis not having clinically bronchoobstructive syndrome in anamnesis are studied. In children with atopic dermatitis the main risk factors of the bronchial asthma development are shown and the possibilities of revealing its early preclinical signs are determined. It is significant in prevention of the bronchial asthma development in timely performance of specific preventive measures.

Correction of pyrimidine derivatives of immunologic activity of the organism and external respiration function for prevention of the lingering course of acute pneumonia

1993 ◽  
Vol 74 (3) ◽  
pp. 193-197
Author(s):  
Yu. D. Slabnov ◽  
D. A. Valimukhametova ◽  
A. P. Tsibulkin ◽  
R. F. Khamitov
Keyword(s):  
Side Effects ◽  
Combined Treatment ◽  
External Respiration ◽  
Pyrimidine Derivatives ◽  
Acute Pneumonia ◽  
Cellular And Humoral Immunity ◽  
Immunologic Activity ◽  
Derivatives Of ◽  
Respiration Function ◽  
Stabilization Period

The effect of xymedon on immunologic indices and external respiration function in combined treatment of patients with acute pnemonia is studied. The use of xymedon in the presence of basis therapy in patients with lingering pneumonia with reduced immunologic reactivity exerts a stimulating effect on the indices of cellular and humoral immunity. This effect is revealed in the stabilization period of pneumonia accompanied by positive clinicoroentgenologic shifts, provides a higher increase of the indices of external respiration function, reduces the terms of recovery of patients. Xymedon does not cause side effects. The drug may be recommended for a wider use in the clinic in patients with unspecific diseases of the lungs.

scholarly journals The prevalence of respiratory symptoms among residents of the Russian Far North

2017 ◽  
Vol 95 (3) ◽  
pp. 260-263 ◽  
Author(s):  
S. V. Andronov ◽  
A. A. Lobanov ◽  
A. I. Popov ◽  
A. V. Emelyanov
Keyword(s):  
Respiratory Function ◽  
Respiratory Symptoms ◽  
Bronchial Obstruction ◽  
External Respiration ◽  
Cross Sectional ◽  
Open Flame ◽  
Far North ◽  
Open Fire ◽  
Sputum Production ◽  
At Home

Aim: to study the frequency of respiratory symptoms among the reindeer herders of the Yamal region in the Far North of Russia. We conducted a cross-sectional study of the occurrence of respiratory symptoms among 500 subjects of the tundra Nenets population (28.1% of the adult Nenets population in the district), of which 38.3% were men and 61.7% women (average age 40.1 years). All patients were matched for age and occupation. Medical examination was carried out by a pulmonologist with the use of the GARD questionnaire (WHO, 2004) and spirometry. Spirometry was performed with a SpiroUSB device (UK) according to a unified standard and the criteria of ATS/ERS 2005. The frequency of respiratory symptoms among the tundra population was estimated at 71.8%. Cough with expectoration and dyspnea were found in 22.8% of the respondents. 70.0% of the examined subjects worked in the cold, 33% were exposed to the open flame at home, and 34.4% smoked. Respiratory symptoms developed in 16.3% of those working in the cold and in 37% exposed to open fire. The combination of such complaints as cough and sputum production occurred in smokers twice as frequently as in non-smokers (54.1%) (p<0.01).The combination of such complaints as cough and sputum production was twice as likely note in his those who smoked (54.1% vs 20.2%) (p<0.01). The combination of these problems dyspnea was three times more common in the smokers (23,3%vs 7,3%) (p<0.001). At presence at patients of such a factor as work in the cold and the absence of other only 16.3% of them have respiratory symptoms. When using at home the open flame and the absence of other factors leading up 37.0% of the individuals with symptoms of chronic bronchitis. Cough, sputum and dyspnea are formed only among 26.3% of the smokers face when smoking is the only risk factor. If the surveyed residents of all three negative factors respiratory symptoms met at 62.1%. Disorders of respiratory function according to spirometry were not observed in none of the study participants. Respiratory symptoms developed in 62.1% of the subjects exposed to all three risk factors. External respiration indices remain normal in all he examine subjects. It is concluded that residents of the Far North frequently suffer respiratory symptoms without disorders in the external respiratory function. In most cases they associated with three factors (work in the cold, exposure to open fire at home, and smoking). Compensatory stimulation of lung functions may create additional difficulties for diagnostics of bronchial obstruction.

scholarly journals Clinical Characteristics of the Combined Course of Chronic Obstructive Pulmonary Disease and Gastroesophagal Reflux Disease

2021 ◽  
Vol 6 (4) ◽  
pp. 91-98
Author(s):  
O. I. Lіakh ◽  
◽  
M. I. Tovt-Korshуnska ◽  
M. A. Derbak
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Pulmonary Disease ◽  
Reflux Disease ◽  
Chronic Obstructive ◽  
External Respiration ◽  
Outpatient Basis ◽  
Obstructive Pulmonary Disease ◽  
Respiration Function

The comorbid diseases can occur at any stage of bronchial obstruction, and, regardless of the severity or phase of chronic obstructive pulmonary disease, significantly affect disability, increase the frequency of hospitalizations, and increase the cost of medical care. The presence of concomitant gastroesophageal reflux disease in patients with chronic obstructive pulmonary disease is an independent aggravating risk factor for exacerbations and is associated with health deterioration of this group of patients. The purpose of the study was to study the features of the clinical course of chronic obstructive pulmonary disease in combination with gastroesophageal reflux disease. Materials and methods. Retrospective analysis of 138 patients who were treated in the pulmonology department for exacerbation of the disease and outpatient treatment by a gastroenterologist was carried out. 3 groups of patients were formed: 1 group (n=60) – patients with chronic obstructive pulmonary disease in combination with gastroesophageal reflux disease, 2 group (n=42) – patients with chronic obstructive pulmonary disease without signs of gastroesophageal reflux disease, who were treated in the pulmonology department for exacerbation of the disease and 3 group (n=36) – patients with gastroesophageal reflux disease who were treated on an outpatient basis. The patients were similar in age, stage of disease and duration of illness. The average age of the patients was 55±1.64. It should be noted, regarding the gender characteristics of the groups, that among the examined patients by gender, men predominated – 78.4% (80 out of 102). Results and discussion. The main clinical and anamnestic features of the combined pathology were studied. The significance of the assessment of functional changes in spirometry indexes in this category of patients is described. A significant decrease in external respiration function was revealed in the indicators of the external respiration function in patients of all groups. In the patients with chronic obstructive pulmonary disease in combination with gastroesophageal reflux disease the frequency of exacerbations increases. These exacerbations were associated with the presence and severity of gastrointestinal symptoms, namely increased heartburn, acid regurgitation causes worsening of respiratory symptoms, until the exacerbation of the disease with subsequent hospitalization. Also the length of stay in the hospital of the patients in this group increased by 1.5±0.4 days, which is associated with a severe exacerbation of chronic obstructive pulmonary disease and the need to use a double dose of glucocorticoids to control the symptoms of respiratory failure. Among the complaints of patients with combined pathology, extraesophageal manifestations of gastroesophageal reflux disease prevailed. Conclusion. The presence of concomitant gastroesophageal reflux disease in patients with chronic obstructive pulmonary disease expands and aggravates the clinical manifestations of the underlying disease

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