scholarly journals Cigarette Smoke and E-Cigarette Vapor Dysregulate Osteoblast Interaction With Titanium Dental Implant Surface

2019 ◽  
Vol 45 (1) ◽  
pp. 2-11 ◽  
Author(s):  
Mahmoud Rouabhia ◽  
Humidah Alanazi ◽  
Hyun Jin Park ◽  
Reginaldo Bruno Gonçalves
Keyword(s):  
Adverse Effects ◽  
Cigarette Smoke ◽  
Dental Implant ◽  
Caspase 3 ◽  
Titanium Implant ◽  
Implant Surface ◽  
Implant Material ◽  
Dental Implant Surface ◽  
Titanium Dental Implant ◽  
Osteoblast Attachment

The purpose of this study was to determine the possible deleterious effects of e-cigarette vapor on osteoblast interaction with dental implant material. Osteoblasts were cultured onto Ti6Al4V titanium implant disks and were then exposed or not to whole cigarette smoke (CS), as well as to nicotine-rich (NR) or nicotine-free (NF) e-vapor for 15 or 30 minutes once a day for 1, 2, or 3 days, after which time various analyses were performed. Osteoblast growth on the titanium implant disks was found to be significantly (P < .001) reduced following exposure to CS and to the NR and NF e-vapors. Osteoblast attachment to the dental implant material was also dysregulated by CS and the NR and NF e-vapors through a decreased production of adhesion proteins such as F-actin. The effects of CS and e-cigarette vapor on osteoblast growth and attachment were confirmed by reduced alkaline phosphatase (ALP) activity and tissue mineralization. The adverse effects of CS and the NR and NF e-vapors on osteoblast interaction with dental implant material also involved the caspase-3 pathway, as the caspase-3 protein level increased following exposure of the osteoblasts to CS or e-vapor. It should be noted that the adverse effects of CS on osteoblast growth, attachment, ALP, and mineralized degradation were greater than those of the NR and NF e-vapors, although the latter did downregulate osteoblast interaction with the dental implant material. Overall results suggest the need to consider e-cigarettes as a possible contributor to dental implant failure and/or complications.

scholarly journals Bioactive Coating on Titanium Dental Implants for Improved Anticorrosion Protection: A Combined Experimental and Theoretical Study

Coatings ◽  
2019 ◽  
Vol 9 (10) ◽  
pp. 612 ◽  
Author(s):  
Jozefina Katić ◽  
Ankica Šarić ◽  
Ines Despotović ◽  
Nives Matijaković ◽  
Marin Petković ◽  
...  
Keyword(s):  
Dental Implant ◽  
Density Functional ◽  
Surface Characterization ◽  
Electrochemical Impedance ◽  
Artificial Saliva ◽  
Titanium Implant ◽  
Attenuated Total Reflection ◽  
Implant Surface ◽  
Bioactive Coating ◽  
Dental Implant Surface

In recent years, extensive studies have been continuously undertaken on the design of bioactive and biomimetic dental implant surfaces due to the need for improvement of the implant–bone interface properties. In this paper, the titanium dental implant surface was modified by bioactive vitamin D3 molecules by a self-assembly process in order to form an improved anticorrosion coating. Surface characterization of the modified implant was performed by field emission scanning electron microscopy (FE-SEM), attenuated total reflection Fourier transform infrared spectroscopy (ATR-FTIR), and contact angle measurements (CA). The implant’s electrochemical stability during exposure to an artificial saliva solution was monitored in situ by electrochemical impedance spectroscopy (EIS). The experimental results obtained were corroborated by means of quantum chemical calculations at the density functional theory level (DFT). The formation mechanism of the coating onto the titanium implant surface was proposed. During a prolonged immersion period, the bioactive coating effectively prevented a corrosive attack on the underlying titanium (polarization resistance in order of 107 Ω cm2) with ~95% protection effectiveness.

Natural Nacre Coatings on Titanium Implant Grown by Fresh Water Bivalve Shell

2006 ◽  
Vol 309-311 ◽  
pp. 743-746 ◽  
Author(s):  
Xiao Xiang Wang ◽  
Lei Xie ◽  
Cheng Luo ◽  
Ri Zhi Wang
Keyword(s):  
Fresh Water ◽  
Dental Implant ◽  
Titanium Surface ◽  
Close Contact ◽  
Titanium Implant ◽  
Biologically Active ◽  
Nacreous Layer ◽  
Transitional Layer ◽  
Implant Surface ◽  
Titanium Dental Implant

Titanium dental implant screws were implanted into the pearl sacs of a fresh water bivalve (hyriopsis cumingii Lea) by replacing the pearls. After 45 days of cultivation, the implant surfaces were deposited with a nacre coating with iridescent luster. The coating was about 200-600 µm in thickness and composed of a laminated nacreous layer and a transitional non-laminated layer that consisted mainly of vaterite and calcite polymorphs of calcium carbonate. The transitional layer was around 2-10 µm thick in the convex and flat region of the implant surface and could form close contact with titanium surface; while the transitional layer was much thicker in the steep concave regions and could not form close contact with the titanium surface. The improvement to the design of the dental implant with respect to this coating method was suggested in the paper. The results suggest that it is possible to fabricate a biologically active and degradable, and mechanically tough and strong nacre coating on titanium dental implant by this novel coating technology.

Titanium Dental Implant Surface Micromorphology Optimization

2007 ◽  
Vol 33 (4) ◽  
pp. 177-185 ◽  
Author(s):  
Gintaras Juodzbalys ◽  
Marija Sapragoniene ◽  
Ann Wennerberg ◽  
Tomas Baltrukonis
Keyword(s):  
Dental Implant ◽  
Implant Surface ◽  
Surface Micromorphology ◽  
Dental Implant Surface ◽  
Titanium Dental Implant

scholarly journals In vitro comparison of two titanium dental implant surface treatments: 3M™ESPE™ MDIs versus Ankylos®

2017 ◽  
Vol 3 (1) ◽  
Author(s):  
Jagjit Singh Dhaliwal ◽  
Juliana Marulanda ◽  
Jingjing Li ◽  
Sharifa Alebrahim ◽  
Jocelyne Sheila Feine ◽  
...  
Keyword(s):  
Dental Implant ◽  
Surface Treatments ◽  
Implant Surface ◽  
Dental Implant Surface ◽  
Titanium Dental Implant ◽  
In Vitro Comparison

scholarly journals A New Insight into Coating’s Formation Mechanism Between TiO2 and Alendronate on Titanium Dental Implant

Materials ◽  
2020 ◽  
Vol 13 (14) ◽  
pp. 3220
Author(s):  
Željka Petrović ◽  
Ankica Šarić ◽  
Ines Despotović ◽  
Jozefina Katić ◽  
Robert Peter ◽  
...  
Keyword(s):  
Dental Implant ◽  
Photoelectron Spectroscopy ◽  
Density Functional ◽  
Electrochemical Impedance ◽  
Organophosphorus Compounds ◽  
Bone Diseases ◽  
Implant Surface ◽  
Dental Implant Surface ◽  
Coating Formation ◽  
Titanium Dental Implant

Organophosphorus compounds, like bisphosphonates, drugs for treatment and prevention of bone diseases, have been successfully applied in recent years as bioactive and osseoinductive coatings on dental implants. An integrated experimental-theoretical approach was utilized in this study to clarify the mechanism of bisphosphonate-based coating formation on dental implant surfaces. Experimental validation of the alendronate coating formation on the titanium dental implant surface was carried out by X-ray photoelectron spectroscopy and contact angle measurements. Detailed theoretical simulations of all probable molecular implant surface/alendronate interactions were performed employing quantum chemical calculations at the density functional theory level. The calculated Gibbs free energies of (TiO2)10–alendronate interaction indicate a more spontaneous exergonic process when alendronate molecules interact directly with the titanium surface via two strong bonds, Ti–N and Ti–O, through simultaneous participation common to both phosphonate and amine branches. Additionally, the stability of the alendronate-modified implant during 7 day-immersion in a simulated saliva solution has been investigated by using electrochemical impedance spectroscopy. The alendronate coating was stable during immersion in the artificial saliva solution and acted as an additional barrier on the implant with overall resistivity, R ~ 5.9 MΩ cm2.

scholarly journals A Possible Relationship between Peri-Implantitis, Titanium Hypersensitivity, and External Tooth Resorption: Metal-Free Alternative to Titanium Implants

2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Andrea Enrico Borgonovo ◽  
Rachele Censi ◽  
Virna Vavassori ◽  
Mauro Savio ◽  
Dino Re
Keyword(s):  
Bone Loss ◽  
Titanium Implant ◽  
Titanium Implants ◽  
Implant Surface ◽  
Tooth Resorption ◽  
Dental Implant Surface ◽  
Titanium Dental Implant ◽  
Nonsurgical Therapy ◽  
Zirconia Implants

Titanium dental implant surface does not remain unaltered but may corrode and release ions or particles which trigger soft and hard tissue damage. Titanium may induce clinically relevant hypersensitivity in patients chronically exposed. A 56-year-old female patient presented peri-implantitis around a single titanium implant positioned three years earlier. Despite nonsurgical therapy, a rapid bone loss associated with pain and swelling occurred, and adjacent teeth presented external resorption. Compromised teeth were removed, and three titanium implants were inserted. Six months later, the patient complained about high mucosa sensitivity and implant exposure. At clinical and radiographic examinations, tissue inflammation and vertical bone loss involved the new implants and the process of external resorption affected the teeth. The blood test confirmed titanium hypersensitivity. Titanium implants were removed, and 5 zirconia implants were placed. No sign of bone loss or tooth resorption was recorded at clinical and radiographic control during 18 months of follow-up.

Sign in / Sign up

Export Citation Format

Share Document