scholarly journals Treatment of Cognitive and Behavioral Disorders in Children Using Transcranial Magnetic Stimulation: Literature Review

2021 ◽  
pp. 524-532
Author(s):  
Julia V. Nesterova ◽  
George A. Karkashadze ◽  
Leila S. Namazova-Baranova ◽  
Elena A. Vishneva ◽  
Elena V. Kaytukova ◽  
...  
Keyword(s):  
Transcranial Magnetic Stimulation ◽  
Behavioral Disorders ◽  
Magnetic Stimulation ◽  
Cognitive Disorders ◽  
Medical Problem ◽  
Speech Disorders ◽  
Noninvasive Treatment ◽  
Modern Approach ◽  
Leading Position ◽  
Stimulation Method

Speech disorders have the leading position among cognitive disorders and represent the urgent medical problem. The modern approach to the treatment of cognitive and behavioral disorders in children consists of the integrity of pharmacotherapeutic, correctional and psychotherapeutic, as well as non-invasive instrumental methods of brain neurostimulation. This article provides the overview of the currently available data on transcranial magnetic stimulation method as noninvasive treatment of various neuropsychiatric disorders in children and its difference from physiotherapeutic methods used in traditional Russian practice.

scholarly journals USE OF TRANSCRANIAL MAGNETIC STIMULATION IN CHILDREN WITH CONSEQUENCES OF PERINATAL BRAIN LESIONS

2016 ◽  
Vol 1 (6) ◽  
pp. 71-75
Author(s):  
Тимофеева ◽  
Olga Timofeeva ◽  
Алимова ◽  
Elena Alimova ◽  
Шпрах ◽  
...  
Keyword(s):  
Cerebral Cortex ◽  
Transcranial Magnetic Stimulation ◽  
Magnetic Stimulation ◽  
Clinical Performance ◽  
Clinical Signs ◽  
Low Frequency ◽  
Speech Development ◽  
Psychological Status ◽  
Neuroprotective Therapy ◽  
Stimulation Method

1249children of 5–10years (716boys, 533girls) with consequences of perinatal lesions of the CNS were examined, 230 of them were treated with the transcranial magnetic stimulation method (TMS). Selection of the TMS regimens was carried out taking into account the specific clinical neurophysiological features of the patients both as monotherapy, as well as a part of complex neurorehabilitation. For example, when intensifying of the synchronizing influences of tha-lamic structures and EEG signs of a delay of formation of electrical cortical rhythmicity, in children with developmental dysphasia and difficulties of school training, a high-pitched stimulation in the projection of the sensomotor and speech zones of a cerebral cortex was chosen; when intensifying of desynchronization influences of a reticular formation of a brainstem; at motor type of a developmental dysphasia and clinical signs of ADHD syndrome, a low-frequency regimen of stimulation of front-parietal and central areas of a cerebral cortex were chosen. Efficiency of therapy within 55–60% concerning indicators of the speech sphere and the psychological status is reached at sessions of TMS together with correctional occupations with auxiliary specialists of the rehabilitation center – speech pathologists and psychologists. Efficiency of monotherapy of TMS in children with retardation of psycho-speech development made 30–35%. Sufficient clinical performance and safety of the technique, a possibility of holding sessions of TMS against the background of course neuroprotective therapy at children with cerebral palsy is shown.

Adverse effects in repetitive transcranial magnetic stimulation – prevention and management

2016 ◽  
Vol 33 (S1) ◽  
pp. S555-S556
Author(s):  
G. Sobreira ◽  
M.A. Aleixo ◽  
C. Moreia ◽  
J. Oliveira
Keyword(s):  
Transcranial Magnetic Stimulation ◽  
Adverse Effects ◽  
Brain Stimulation ◽  
Magnetic Stimulation ◽  
Repetitive Transcranial Magnetic Stimulation ◽  
Screening Tools ◽  
Noninvasive Treatment ◽  
Pubmed Database ◽  
Invaluable Tool ◽  
Competing Interest

IntroductionRepetitive Transcranial Magnetic Stimulation (rTMS), through modulation of cortical activity, has become an invaluable tool in experimental and clinical neurosciences. Although this form of noninvasive treatment is considered safer than other means of brain stimulation it has been associated with adverse effects (AE).ObjectiveTo make a brief review, concerning the AE of rTMS, their prevention and management.AimsTo understand and be able to deal with the most common AE associated with rTMS.MethodsA PubMed database search, using as keywords “Transcranial magnetic stimulation”, “Repetitive Transcranial magnetic stimulation”; “adverse effects”; “management” and “guidelines” between the year 1998 and 2015.ResultsAE caused by rTMS are rare. They can be classified into severe (seizures) and mild (syncope, and transient hearing impairment, acute psychiatric changes, headache, local pain, neck pain, toothache, paresthesia and cognitive/neuropsychological changes) and into early and late AE. In order to obviate and avoid them, guidelines have been created; some state that to apply rTMS the technician needs to obtain the patient's informed consent and assess the risks/benefit ratio. To meet these criteria, screening tools have been created, and since then the number of AE has reduced.ConclusionsEven though rTMS is considered safer than other forms of brain stimulation it is still associated with AE. In order to avoid them, screening tools have been created allowing the clinician to assess the risks and benefits of applying this technique.Disclosure of interestThe authors have not supplied their declaration of competing interest.

Enhancing the effects of transcranial magnetic stimulation with intravenously injected magnetic nanoparticles

2019 ◽  
Vol 7 (6) ◽  
pp. 2297-2307 ◽  
Author(s):  
Rongrong Li ◽  
Jun Wang ◽  
Xiaoya Yu ◽  
Pengfei Xu ◽  
Shuai Zhang ◽  
...  
Keyword(s):  
Magnetic Nanoparticles ◽  
Transcranial Magnetic Stimulation ◽  
Brain Stimulation ◽  
Neurological Disorders ◽  
Magnetic Stimulation ◽  
Non Invasive ◽  
Stimulation Method ◽  
The Brain

Magnetic nanoparticles SPIONs are non-invasively introduced into the brain to enhance the effects of a non-invasive clinical brain stimulation method for treating neurological disorders.

scholarly journals Jitter of Corticospinal Neurons During Repetitive Transcranial Magnetic Stimulation. Method and Possible Clinical Implications

2014 ◽  
Vol 7 (4) ◽  
pp. 580-586 ◽  
Author(s):  
Pietro Caliandro ◽  
Luca Padua ◽  
Alessandro Rossi ◽  
Paolo Maria Rossini ◽  
Erik Stalberg ◽  
...  
Keyword(s):  
Transcranial Magnetic Stimulation ◽  
Magnetic Stimulation ◽  
Repetitive Transcranial Magnetic Stimulation ◽  
Clinical Implications ◽  
Stimulation Method

scholarly journals Setup presentation and clinical outcome analysis of treating highly language-eloquent gliomas via preoperative navigated transcranial magnetic stimulation and tractography

2018 ◽  
Vol 44 (6) ◽  
pp. E2 ◽  
Author(s):  
Nico Sollmann ◽  
Anna Kelm ◽  
Sebastian Ille ◽  
Axel Schröder ◽  
Claus Zimmer ◽  
...  
Keyword(s):  
Transcranial Magnetic Stimulation ◽  
Clinical Outcome ◽  
Magnetic Stimulation ◽  
Awake Surgery ◽  
Outcome Analysis ◽  
Navigated Transcranial Magnetic Stimulation ◽  
Language Mapping ◽  
Language Deficits ◽  
Modern Approach ◽  
Duration Of Surgery

OBJECTIVEAwake surgery combined with intraoperative direct electrical stimulation (DES) and intraoperative neuromonitoring (IONM) is considered the gold standard for the resection of highly language-eloquent brain tumors. Different modalities, such as functional magnetic resonance imaging (fMRI) or magnetoencephalography (MEG), are commonly added as adjuncts for preoperative language mapping but have been shown to have relevant limitations. Thus, this study presents a novel multimodal setup consisting of preoperative navigated transcranial magnetic stimulation (nTMS) and nTMS-based diffusion tensor imaging fiber tracking (DTI FT) as an adjunct to awake surgery.METHODSSixty consecutive patients (63.3% men, mean age 47.6 ± 13.3 years) suffering from highly language-eloquent left-hemispheric low- or high-grade glioma underwent preoperative nTMS language mapping and nTMS-based DTI FT, followed by awake surgery for tumor resection. Both nTMS language mapping and DTI FT data were available for resection planning and intraoperative guidance. Clinical outcome parameters, including craniotomy size, extent of resection (EOR), language deficits at different time points, Karnofsky Performance Scale (KPS) score, duration of surgery, and inpatient stay, were assessed.RESULTSAccording to postoperative evaluation, 28.3% of patients showed tumor residuals, whereas new surgery-related permanent language deficits occurred in 8.3% of patients. KPS scores remained unchanged (median preoperative score 90, median follow-up score 90).CONCLUSIONSThis is the first study to present a clinical outcome analysis of this very modern approach, which is increasingly applied in neurooncological centers worldwide. Although human language function is a highly complex and dynamic cortico-subcortical network, the presented approach offers excellent functional and oncological outcomes in patients undergoing surgery of lesions affecting this network.

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