scholarly journals Bacteriostatic and bactericidal activities of Acalypha indica L. plant leave extracts on bacteria shigella disenteriae type 1 in vitro

2021 ◽  
Vol 8 (6) ◽  
pp. 304-309
Author(s):  
Abdul Majid ◽  
Frans Salesman
Keyword(s):  
Experimental Study ◽  
Bactericidal Activity ◽  
Pathogenic Bacteria ◽  
Shigella Dysenteriae ◽  
Herbal Extract ◽  
Bactericidal Activities ◽  
Acalypha Indica ◽  
Shigella Dysenteriae Type

This study aimed to analyze the bacteriostatic and bactericidal activity of Acalypha indica L. extract against Shigella dysenteriae type 1 bacteria in vitro. This research is a laboratory experimental study consisting of six concentration treatments, namely: (K = 0/ml, P1 = 100/ml, P2 = 200/ml, P3 = 400/ml, P4 = 800/ml, P5 = 1600 mg/ml ), and five replications each. The results showed that the herbal extract of Acalypha indica L. was bacteriostatic (inhibiting) at a concentration of 400 mg/mm, and bactericidal (killing) the bacteria Shigella dysenteriae type 1, which was tested in vitro at a concentration of at least 800 mg/ml. It is necessary to study the effect of Acalypha indica L. herbal extract from Timor in the serum of Rattus norwegicus against bacteria that cause bloody diarrhea (EHEC O157:H7, and Shigella dysenteriae type 1), MRSA bacteria, and other pathogenic bacteria.

scholarly journals In vivo versus in vitro protein abundance analysis of Shigella dysenteriae type 1 reveals changes in the expression of proteins involved in virulence, stress and energy metabolism

2011 ◽  
Vol 11 (1) ◽  
pp. 147 ◽  
Author(s):  
Srilatha Kuntumalla ◽  
Quanshun Zhang ◽  
John C Braisted ◽  
Robert D Fleischmann ◽  
Scott N Peterson ◽  
...  
Keyword(s):  
Energy Metabolism ◽  
Shigella Dysenteriae ◽  
Protein Abundance ◽  
Shigella Dysenteriae Type ◽  
Vitro Protein

Synthesis of specifically monofluorinated ligands related to the O-polysaccharide of Shigella dysenteriae type 1

1994 ◽  
Vol 259 (1) ◽  
pp. 21-34 ◽  
Author(s):  
Laurence A. Mulard ◽  
Paul Kováč ◽  
Cornelis P.J. Glaudemans
Keyword(s):  
Shigella Dysenteriae ◽  
Shigella Dysenteriae Type

scholarly journals Antimicrobial evaluation of methyl 4-O-Acetyl-α-L-Rhamnopyranoside derivatives

2013 ◽  
pp. 33-43
Author(s):  
Mohammed M Matin ◽  
Mohammad Ibrahim ◽  
Md Shafiqur Rahman
Keyword(s):  
Pathogenic Bacteria ◽  
Pathogenic Fungi ◽  
Macrophomina Phaseolina ◽  
Antibacterial Activities ◽  
Salmonella Typhi ◽  
Shigella Dysenteriae ◽  
Curvularia Lunata ◽  
In Vitro Antibacterial Activity ◽  
Antimicrobial Evaluation

A number of 2,3-di-O-acyl derivatives (6-11) of methyl 4-O-acetyl-a-Lrhamnopyranoside (5) obtained by using various acylating agents were screened for in vitro antifungal activity against four plant pathogenic fungi, viz., Alternaria alternata, Curvularia lunata. Fusarium equiseti and Macrophomina phaseolina. These compounds were also screened for in vitro antibacterial activity against ten human pathogenic bacteria, viz., Bacillus subtilis, Bacillus cereus, Bacillus megaterium, Staphylococcus aureus, Escherichia coli, INABA ET (Vibrio), Pseudomonas species, Salmonella paratyphi, Shigella dysenteriae and Salmonella typhi. The study reveal that these 4-O-acetyl-?-L-rhamnopyranoside derivatives are more prone towards antifungal activities than that of antibacterial activities. DOI: http://dx.doi.org/10.3329/cujbs.v3i1.13404 The Chittagong Univ. J. B. Sci.,Vol. 3(1&2):33-43, 2008

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