scholarly journals Effect of Solanium melongena fruits supplemented diet on Hyperglycemia, Overweight, Liver function and Dyslipidemia in Male New Zealand Rabbits fed High fat and Sucrose diet

2018 ◽  
Vol 4 (3) ◽  
Author(s):  
Nwozo SO ◽  
Adeneye DA ◽  
Nwawuba SU
Keyword(s):  
New Zealand ◽  
Liver Function ◽  
High Fat ◽  
Sucrose Diet ◽  
New Zealand Rabbits

Ameliorative effect of fermented Pentaclethra macrophylla (African oil bean seed) on high fat diet and sucrose drink induced metabolic syndrome in male New Zealand rabbits.

2019 ◽  
Vol 5 (1) ◽  
pp. 42-48
Author(s):  
Nwozo Onyenibe ◽  
Daramola Victoria ◽  
Nwawuba Udogadi
Keyword(s):  
Metabolic Syndrome ◽  
New Zealand ◽  
Normal Control ◽  
High Fat Diet ◽  
Bean Seed ◽  
High Fat ◽  
Treatment And Prevention ◽  
Elevated Glucose ◽  
Ameliorative Effect ◽  
New Zealand Rabbits

The consumption of nutraceuticals has become progressively popular in improving health, as well as disease treatment and prevention. The aim of this study is to evaluate the ameliorative effect of fermented Pentaclethra macrophylla (African oil bean) seed on high fat diet and sucrose drink induced metabolic syndrome in male New Zealand rabbits. All experimental procedures were carried using standard methods. A total of twenty (20) rabbits were used for this study, the animals were randomly grouped into five (5) groups with four (4) animals each. Metabolic syndrome risk factors obesity, hypertension, dyslipidemia and hyperglycemia were determined. HFD+30%SUC had over 1500g body weight (bwt) and fasting blood sugar (FBS) 239.50±5.74 mg/dl  relative to the normal control with 1000±6.73g and 77.00±5.94 respectively whereas ND+30%SUC had lower FBS (l172.50±2.52) compared to HFD+30%SUC. There was a significant p<0.05 increase in body weights in treated groups with 1274±11.19g, 1282.75±4.99g, 1285±4.76g and FBS levels in mg/dL198.25±4.79, 198.75±8.06, 200±3.74 in rabbits  compared to untreated HFD+30%SUC. Glycated hemoglobin, and ?-Amylase were significantly p<0.05 elevated, glucose-6-phosphate dehydrogenase levels were significantly p<0.05 reduced, lipid profile markers (HDL, TRIG & CHOL), electrolytes (sodium, potassium, calcium), urea and creatinine levels were significantly p<0.05 altered in HFD+30%SUC exposed group relative to the normal control and ND+30%SUC. However, dietary supplementation with fermented Pentaclethra macrophylla seeds caused weight, FBS, serum lipid reduction and potentiated electrolyte, urea and creatinine levels. Therefore, according to our results, fermented Pentaclethra macrophylla seed is an excellent nutraceutical and its consumption should be encouraged in modifying high fat and elevated intake of sucrose in rabbit

scholarly journals A Diet High in Saturated Fat and Sucrose Alters Glucoregulation and Induces Aortic Fatty Streaks in New Zealand White Rabbits

2002 ◽  
Vol 3 (3) ◽  
pp. 179-184 ◽  
Author(s):  
Weidong Yin ◽  
Zhonghua Yuan ◽  
Zongbao Wang ◽  
Baotang Yang ◽  
Yongzong Yang
Keyword(s):  
Nitric Oxide ◽  
New Zealand ◽  
Fatty Streak ◽  
Peripheral Vascular ◽  
High Fat ◽  
New Zealand White Rabbits ◽  
Sucrose Diet ◽  
High Sucrose Diet ◽  
Artery Disease ◽  
High Sucrose

A new and convenient animal model for studying peripheral vascular and coronary artery disease in diabetes was established in this study. Male New Zealand White rabbits weighing approximately 2 kg were divided into 2 groups: a normal control group fed standard laboratory chow and a diabetogenic diet–fed group received a high-fat/high-sucrose diet. The high-fat/high-sucrose diet (contained 10% lard and 37% sucrose) feeding was maintained for 6 months. Plasma total cholesterol, high-density lipoprotein (HDL) cholesterol, triglyceride, superoxide dismutase, nitric oxide, nitric oxide synthase, insulin, and glucose were quantitated at monthly or bimonthly intervals. The aortic fatty streak lesions were quantified following lipid staining with Sudan IV. The aortic samples were observed by electron microscopy. High plasma triglyceride and glucose concentrations were induced. At the end of 6 months, the aortic fatty streak lesions were present in the animals' vascular specimens. As far as we know, this is the first report that demonstrates that New Zealand White rabbits can develop obvious aortic fatty streaks by feeding a high-fat/high-sucrose diet. Our results suggest that NewZealand White rabbits fed a high-fat/high-sucrose diet would provide a convenient model for studying peripheral vascular and coronary artery disease in diabetes.

Subtoxicdose of Chlorpyrifos Down Regulates ABCA1 Expression and Accelerates Formation of Atherosclerosis Induced by The High Fat Diet in New Zealand Rabbits*

2011 ◽  
Vol 38 (1) ◽  
pp. 46-54
Author(s):  
Shou-Hong ZHOU ◽  
Xu-Hong YANG ◽  
Tao SONG ◽  
Shu-Jin WU ◽  
Ning-Jiang HUANG ◽  
...  
Keyword(s):  
New Zealand ◽  
High Fat Diet ◽  
High Fat ◽  
Abca1 Expression ◽  
New Zealand Rabbits

Antiurolithiatic effect of Cymbopogon Proximus, Alhagi Maurorum, on Sulfadimidine induced urolithiasis in male New Zealand rabbits

2019 ◽  
Vol 20 (1) ◽  
pp. 12-18
Author(s):  
Sameh El-Nabtity
Keyword(s):  
New Zealand ◽  
Intramuscular Injection ◽  
Negative Control Group ◽  
Negative Control ◽  
Control Group ◽  
Aqueous Extracts ◽  
Blood And Urine Samples ◽  
Group 2 ◽  
New Zealand Rabbits ◽  
Group 1

The present study aimed to investigate the prophylactic effect of Cymbopogon proximus and Alhagi maurorum on Sulfadimidine induced urolithiasis in rabbits . Thirty New Zealand male rabbits were allocated into six equal groups (each of five): Group (1) was used as a negative control. Group(2) were administered sulfadimidine (200mg/kg) by intramuscular injection.Groups(3) and (4) were administered sulfadimidine(200mg/kg) by intramuscular injection and 330mg/kg of Cymbopogon proximus alcoholic and aqueous extracts respectively orally.Groups(5) and (6) were administered sulfadimidine(200mg/kg) by intramuscular injection and 400mg/kg of Alhagi maurorum alcoholic and aqueous extracts respectively orally. The period of experiment was 10 days. Blood and urine samples were collected from rabbits on the 10th day. The results recorded a significant decrease in serum creatinine, urea, uric acid and crystalluria in Cymbopogon proximus and Alhagi maurorum groups compared to sulfadimidine treated group.We conclude that Cymbopogon proximus and Alhagi maurorum have a nephroprotective and antiurolithiatic effects against sulfadimidine induced crystalluria.

Does a high-fat/high-sucrose diet accelerate joint damage development when compared to a high-fat diet in a Wistar Han rat groove model of osteoarthritis?

2021 ◽  
Vol 29 ◽  
pp. S104-S105
Author(s):  
J.L Rios ◽  
K. Warmink ◽  
D.R. van Valkengoed ◽  
N.M. Korthagen ◽  
H.H. Weinans
Keyword(s):  
High Fat Diet ◽  
Joint Damage ◽  
High Fat ◽  
Damage Development ◽  
Sucrose Diet ◽  
High Sucrose Diet ◽  
High Sucrose

scholarly journals Effects of soy hull polysaccharide on dyslipidemia and pathoglycemia in rats induced by a high-fat-high-sucrose diet

2022 ◽  
Vol 11 (1) ◽  
pp. 49-57
Author(s):  
Qian Lin ◽  
Lina Yang ◽  
Lin Han ◽  
Ziyi Wang ◽  
Mingshuo Luo ◽  
...  
Keyword(s):  
High Fat ◽  
Soy Hull ◽  
Sucrose Diet ◽  
High Sucrose Diet ◽  
High Sucrose
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