Is restless legs syndrome in Parkinson disease patients associated with any specific factor?

2021 ◽  
Vol 79 (1) ◽  
pp. 38-43
Author(s):  
Manoel Alves SOBREIRA-NETO ◽  
Márcio Alexandre PENA-PEREIRA ◽  
Emmanuelle Silva Tavares SOBREIRA ◽  
Marcos Hortes Nisihara CHAGAS ◽  
Carlos Maurício Oliveira de ALMEIDA ◽  
...  
Keyword(s):  
Parkinson Disease ◽  
Restless Legs Syndrome ◽  
Rating Scale ◽  
Univariate Analysis ◽  
Cross Sectional Study ◽  
Lower Limbs ◽  
Specific Factor ◽  
Cross Sectional ◽  
Restless Legs

ABSTRACT Background: Restless legs syndrome or Willis-Ekbom disease is a disorder characterized by unpleasant sensations associated with the need to mobilize the lower limbs. In Parkinson disease patients, restless legs syndrome is associated with worse quality of life and excessive sleepiness. Regarding other factors, results of different studies are controversial. Objective: To determine the factors associated with the restless legs syndrome presence in Parkinson disease patients. Methods: A cross-sectional study was conducted in 88 consecutive Parkinson disease patients from the outpatient clinic for 21 months. Participants underwent a clinical interview, assessment based on standardized scales (Epworth Sleepiness Scale, Parkinson Disease Questionnaire - 39, Pittsburgh Sleep Quality Index, International Restless Legs Syndrome Study Group rating scale), and video-polysomnography. Results: Out of the 88 participants, 25 had restless legs syndrome. In the multivariate analysis, restless legs syndrome in Parkinson disease has been associated with the symptom of smell loss and quality of sleep and life. In the univariate analysis, restless legs syndrome in Parkinson disease has occurred more frequently in women with higher frequency of insomnia, constipation, and anosmia than in the group without restless legs syndrome. Conclusion: Restless legs syndrome is a prevalent condition in patients with Parkinson disease and is associated with specific characteristics in this group of patients.

The Relationship between Restless Legs Syndrome and Quality of Life in Patients with Myasthenia Gravis

2019 ◽  
Vol 81 (3-4) ◽  
pp. 205-208
Author(s):  
Monica F. Ataide ◽  
Carolina da Cunha-Correia ◽  
Katia C.L. Petribú
Keyword(s):  
Quality Of Life ◽  
Myasthenia Gravis ◽  
Restless Legs Syndrome ◽  
Rating Scale ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Restless Legs ◽  
Study Population ◽  
Clinical Conditions

Background: Restless legs syndrome (RLS) is characterized for an uncomfortable sensation in legs and an irresistible desire to move them. This disorder has been more recently recognized in patients with myasthenia gravis (MG) and can interfere with the quality of life (QOL). Objectives: The aims of this study are to describe the prevalence of RLS and its severity and influence on the QOL in patients with MG. Method: This was a cross-sectional study conducted from May to June 2016 in Recife, Brazil. A sample of 42 patients was interviewed using a sociodemographic questionnaire, MG QOL questionnaire-15 and The RLS Rating Scale. Results: RLS was present in 47.6% of patients and of these 40.5% met moderate to severe RLS criteria. Patients were 45 years on average (SD ± 14.4) and women represented 57.1% of the study population. Among patients with RSL, the quality-of-life scores were worse (p = 0.010) on average. There was no association of RLS with the duration of MG, use of immunosuppressant or clinical conditions that could mimic the occurrence of RLS. Conclusion: RLS is a prevalent condition in patients with MG, and may be severe enough to negatively impact QOL.

scholarly journals Correlation of Anaemia and Restless Legs Syndrome in Elderly: A Cross-sectional Study

2020 ◽  
Author(s):  
Abhijit Agrawal ◽  
Jahnabi Bhagawati ◽  
Sunil Kumar
Keyword(s):  
Serum Ferritin ◽  
Restless Legs Syndrome ◽  
Rating Scale ◽  
Cross Sectional Study ◽  
Severe Anaemia ◽  
World Health ◽  
Sectional Study ◽  
Cross Sectional ◽  
Clinical Criteria ◽  
Restless Legs

Introduction: Restless Legs Syndrome (RLS) also known as Willis Ekbom Disease (WED) which manifests as a neurologic disorder among patients with anaemia, particularly with iron deficiency anaemia. Aim: To find the association of anaemia with RLS in the elderly population. Materials and Methods: In this cross-sectional study, 100 patients of age ≥60 years were enrolled and categorised into mild, moderate, and severe anaemia as per World Health Organisation (WHO) criteria. Every participant was enquired about RLS via a questionnaire based on the International RLS Study Group Rating Scale (IRLSSGRS) for its Severity and for the diagnosis (Essential clinical criteria for the diagnosis of RLS). Results: The study showed that patients with anaemia had a statistically significant correlation with RLS (p=0.04) and severity of RLS (p=0.032). Serum ferritin levels too showed a statistically significant correlation with RLS (p=0.032). Conclusion: Patients with severe anaemia and lower serum ferritin levels were more prone to RLS and had more RLS severity.

scholarly journals Prevalence of Restless Legs Syndrome among Medical Students of Karachi: An Experience from a Developing Country

2020 ◽  
Vol 2020 ◽  
pp. 1-5
Author(s):  
M. Ishaq ◽  
S. U. Riaz ◽  
N. Iqbal ◽  
S. Siddiqui ◽  
A. Moin ◽  
...  
Keyword(s):  
Medical Students ◽  
Sleep Disturbance ◽  
Restless Legs Syndrome ◽  
Rating Scale ◽  
Smoking Status ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Restless Legs ◽  
Chief Complaints ◽  
Study Population

Background. Restless legs syndrome (RLS) is a neurological disorder characterized by an uncomfortable sensation in the legs which gets worse in the evening or night, relieved upon movement. The aim of this study was to specify the prevalence of RLS in the group of young medical students and to assess the effect of RLS on sleep, as sleep disturbance is one of the chief complaints of RLS patients. We also studied its association with smoking as it is considered an aggravating factor. Method. This was a cross-sectional study conducted from June 2017 to July 2018 in Karachi. A total of 300 students (220 females and 80 males) participated and were given questionnaires to detect RLS based on criteria proposed by the International Restless Legs Syndrome Study Group. Subjects who were positive for RLS were further asked questions about sleep by using the Epworth Sleepiness Scale and severity of RLS by using RLS Rating Scale. They were also asked about their smoking status. Results. The frequency of RLS is 8% among young adults. Out of 300 medical students, 24 students were classified positive for RLS with a female preponderance (66.7% were females and 33.3% were males). The severity of RLS was more rated to be mild to moderate. The effect of RLS on sleep was in the mild range. The p value of smoking status comparing with gender came out to be <0.001, and p value of RLS is 0.773. Conclusion. It is concluded that we found RLS to be present significantly in our population that is without comorbidities. Our results showed female preponderance and a mild sleep disturbance in our study population. More attention is needed to recognize RLS and to manage the aggravating factors of RLS.

scholarly journals Restless Legs Syndrome in Dialysis Patients: Does the Dialysis Modality Influence Its Occurrence and Severity?

2018 ◽  
Vol 2018 ◽  
pp. 1-6 ◽  
Author(s):  
Andreia Freire de Menezes ◽  
Douglas Rafanelle Moura de Santana Motta ◽  
Fernanda Oliveira de Carvalho ◽  
Eduesley Santana-Santos ◽  
Manoel Pacheco de Andrade Júnior ◽  
...  
Keyword(s):  
Restless Legs Syndrome ◽  
Rating Scale ◽  
International Study ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Dialysis Patients ◽  
Cross Sectional ◽  
Restless Legs ◽  
International Study Group ◽  
Dialytic Modality

Background. Restless legs syndrome (RLS) is more prevalent in chronic kidney patients than in the general population, but it is often diagnosed late and its predictors are unknown. Purpose. To diagnose RLS in a group of chronic kidney patients on dialysis, determine its frequency and severity, compare the prevalence and severity of the condition among dialytic modalities, and identify possible predictive factors in this population. Methods. An observational and cross-sectional study with 326 patients who had been on dialysis for more than 3 months, 241 on hemodialysis (HD) and 85 on automatic peritoneal dialysis (APD), using the criteria established by the International Study Group on RLS for the diagnosis and the RLS Rating Scale to determine its severity. Results. RLS was diagnosed in 19.3% of the patients, 52.4% with severe or very severe forms. Patients with and without RLS did not differ in clinical and demographic characteristics and dialytic modality; however, patients on APD presented higher RLS severity compared to the HD group. Conclusions. RLS is frequent in dialysis patients and occurs predominantly in its most severe forms; the dialytic modality seems to have no influence on its occurrence; however, it is more severe in patients on APD.

scholarly journals Prevalence and Clinical Characteristics of the Restless Legs Syndrome (RLS) in Patients Diagnosed with Attention Deficit Hyperactivity Disorder (ADHD) in Antioquia

2018 ◽  
Vol 11 (1) ◽  
pp. 58-69 ◽  
Author(s):  
Ana Carolina Sierra Montoya ◽  
Sandra Catalina Mesa Restrepo ◽  
Jorge Mauricio Cuartas Arias ◽  
William Cornejo Ochoa
Keyword(s):  
Attention Deficit Hyperactivity Disorder ◽  
Restless Legs Syndrome ◽  
Attention Deficit ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Children With Adhd ◽  
Clinical Criteria ◽  
Restless Legs ◽  
Hyperactivity Disorder ◽  
Behavioral Issue

Introduction: Attention Deficit Hyperactivity Disorder (ADHD) is the most common behavioral issue for children. One of the sleeping disorders most frequently related to ADHD is the Restless Legs Syndrome (RLS), characterized by an irresistible urge to move the legs, something that is generally associated with paresthesias and motor restlessness. The prevalence rate of RLS in children diagnosed with ADHD is close to 18%, but in Colombia, these cases have been hardly studied. Objective: To determine the frequency of RLS, in children with ADHD. Methods: A cross-sectional study, filled out by parents of children diagnosed with ADHD, were analyzed. This questionnaire contained clinical criteria for classifying ADHD according to the DSM-IV, as well as diagnostic criteria for RLS by the National Institutes of Health (2003). Results: A predominance rate of 65.6% in combined ADHD was observed in children with RLS criteria. Upon carrying out an exploratory data analysis, it was found that having a family history of RLS and belonging to the middle or low socioeconomic strata are conditions associated with the presence of RLS in children with ADHD, with a significant p (p < 0.000) and a PR of 4.47 (3.16-6.32). Conclusions: The prevalence of RLS was similar to the findings of other clinical investigations. However, it highlights new prevalence values in relation to the comorbidity between ADHD and RLS, suggesting the need for new clinical and therapeutic alternatives amidst the presence of both syndromes.

scholarly journals Restless legs syndrome in patients on chronic hemodialysis in a Brazilian city: frequency, biochemical findings and comorbidities

2003 ◽  
Vol 61 (3B) ◽  
pp. 723-727 ◽  
Author(s):  
Gilberto S. Goffredo Filho ◽  
Cláudia C. Gorini ◽  
Andrei S. Purysko ◽  
Herta C. Silva ◽  
Ibrahim Eduardo F. Elias
Keyword(s):  
Restless Legs Syndrome ◽  
Cross Sectional Study ◽  
Chronic Hemodialysis ◽  
Chronic Glomerulonephritis ◽  
Study Group ◽  
Sectional Study ◽  
Cross Sectional ◽  
Restless Legs ◽  
Biochemical Variables ◽  
Biochemical Abnormalities

OBJECTIVE: To evaluate the frequency of restless legs syndrome (RLS) in patients with chronic renal failure (CRF) in Petrópolis, Brazil, and investigate associations between the syndrome and: demographic characteristics, biochemical variables and comorbidities. METHOD: A cross-sectional study in which we interviewed 176 patients on dialytic therapy based on criteria elaborated by the International Restless Legs Syndrome Study Group, and compared data of patients with and without RLS. RESULTS: The frequency was 14.8 %. There were no significant differences between the two groups in demographic and biochemical variables investigated (iron, creatinine, intact parathyroid hormone, hemoglobin, calcium, phosphate). We found no association between RLS and the most common comorbidities, except for chronic glomerulonephritis (CGN) (OR = 3.84, p < 0.01). CONCLUSION: In the studied population RLS is a common disorder, and is not associated with the investigated biochemical abnormalities. A higher frequency of RLS in subjects with CGN is a finding that needs further investigation.

scholarly journals Specialty Physician Designation in Referrals from a Vertically Integrated PCMH

2019 ◽  
Vol 6 ◽  
pp. 233339281985038
Author(s):  
Andrew D. Schreiner ◽  
Keri T. Holmes-Maybank ◽  
Jingwen Zhang ◽  
Justin Marsden ◽  
Patrick D. Mauldin ◽  
...  
Keyword(s):  
Medical Home ◽  
Univariate Analysis ◽  
Cross Sectional Study ◽  
Individual Characteristics ◽  
Patient Centered Medical Home ◽  
Patient Centered ◽  
Cross Sectional ◽  
Medical Specialties ◽  
The Individual

Introduction: Primary care referrals to specialty physicians once relied upon the medical skill of the specialist, the quality of past communication, and previous consultative experiences. As health systems vertically integrate, patterns of specialty physician referral designation are not known. Methods: This cross-sectional study from a patient-centered medical home (PCMH) evaluated the proportion of referrals with named specialists. All outpatient specialty referrals from the PCMH between July and December of 2014 were eligible for inclusion, and 410 patients were randomly selected for chart review. The outcome of interest was specialty physician designation. Other variables of interest included PCMH provider experience, the reason for referral, and time to specialty visit. Univariate analysis was performed with Fisher exact tests. Results: Of 410 specialty referrals, 43.7% were made to medical specialties, 41.7% to surgical specialties, and 14.6% to ancillary specialties. Resident physicians placed 224 referrals (54.6%), faculty physicians ordered 155 (37.8%), and advanced practice providers ordered 31 (7.6%). Only 11.2% of the specialty referral orders designated a specific physician. No differences appeared in the reason for referral, the referral destination, the proportion of visits scheduled and attended, or the time to schedule between those referrals with and without specialty physician designation. Faculty physicians identified a specific specialist in 21.4% of referrals compared to residents doing so in 4.9% ( P < .0001). Conclusion: Patient-centered medical home referrals named a specific specialty physician infrequently, suggesting a shift from the historical reliance on the individual characteristics of the specialist in the referral process.

scholarly journals Psychological distress of patients suffering from restless legs syndrome: a cross-sectional study

2011 ◽  
Vol 9 (1) ◽  
pp. 73 ◽  
Author(s):  
Hanna Scholz ◽  
Heike Benes ◽  
Svenja Happe ◽  
Juergen Bengel ◽  
Ralf Kohnen ◽  
...  
Keyword(s):  
Psychological Distress ◽  
Restless Legs Syndrome ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Restless Legs

scholarly journals Association between quality of life and severity of menopausal symptoms among Saudi women in Al-Ahsa

2021 ◽  
Vol 11 (12) ◽  
pp. 82
Author(s):  
Ola Mousa ◽  
Fatemah M. Alkhars ◽  
Mashael T. Al Shawaf ◽  
Enas A. Al Omran ◽  
Rawan A. Alkhawajah ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Rating Scale ◽  
Negative Impact ◽  
Positive Association ◽  
Cross Sectional Study ◽  
Menopausal Symptoms ◽  
Reproductive Age ◽  
Cross Sectional ◽  
Saudi Women

Background and objective: Menopause is not an illness. It is a normal physiologic process at the time that marks the end of the menstrual cycles. The severity, frequency, duration, and impact of these menopausal symptoms vary from woman to woman according to their age, and they affect the overall quality of life. The aim of this study is to verify the severity of menopausal symptoms experienced by Saudi women in Al Ahsa, and to identify the association between the severity of menopausal symptoms and their effects on the quality of life of Saudi women.Methods: An analytical cross- sectional study involved 427 women aged 45-60 years old. They were randomly collected by researchers who interviewed them in outpatient clinics and obstetrics and gynecology wards from 6 hospitals by using the Menopause Rating Scale (MRS) questionnaire and the Menopause Specific Quality of Life (MENQOL) questionnaire between February 15, 2021 and May 15, 2021.Results: The average age of participants was between 45-49. The MRS shows that mild symptoms were found in 47.8% of participants, while severe symptoms were 10.6%. The most common symptoms were physical and somatic. The Menopause Specific Quality of Life shows that 52.2% of the participants suffer from mild bothersome, while 7.5% have extremely bothersome. There was a strong positive association between menopause specific quality of life, and menopausal symptoms.Conclusions: There was a positive correlation between menopausal symptoms and the quality of life of women. Menopausal symptoms have a negative impact on the quality of women's lives. Therefore, the policy makers in the ministry of health could strengthen providing health programmes and health services to women in this age group, besides women in the reproductive age. This can be accomplished by including modules related to the special health needs of menopausal women in the primary center's health programs.

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