scholarly journals Omega-3 intake in people with epilepsy under regular hemodialysis program: here to stay

2013 ◽  
Vol 71 (7) ◽  
pp. 474-477
Author(s):  
Carla Alessandra Scorza ◽  
Ricardo Mario Arida ◽  
Roberta Monterazzo Cysneiros ◽  
Esper Abrão Cavalheiro ◽  
Fulvio Alexandre Scorza

Among the many risk factors suggested for sudden unexpected death in epilepsy (SUDEP), higher frequency of seizures is a very consistent issue. Furthermore, it has been established that hemodialysis-associated seizure is a complication of the dialysis procedure. Thus, since a possible relation between cardiovascular abnormalities and SUDEP among patients with chronic renal insufficiency in regular hemodialysis program should not be neglected, we propose in this paper that omega-3 fatty acids offer opportunities for prevention of sudden cardiac death or improved treatment in people with epilepsy under the regular hemodialysis program.

2009 ◽  
Vol 67 (3b) ◽  
pp. 922-926 ◽  
Author(s):  
Roberta M. Cysneiros ◽  
Vera C. Terra ◽  
Hélio R. Machado ◽  
Ricardo M. Arida ◽  
José Salomão Schwartzman ◽  
...  

Autism spectrum disorders (ASD) are neurodevelopment disorders that cause severe and pervasive impairment in socialization, communication, and behavior. Although the availability of antipsychotic treatment in ASD has expanded, we will be very careful with side effects of these pharmacological agents. Following this reasoning, emerging data indicate that some antipsychotics may be associated with cardiovascular adverse events (e.g., QT interval prolongation), suggesting that this could be correlated to sudden death. Quite interesting, substantial evidence from epidemiological and case-control studies indicates that omega-3 reduces the risk of cardiovascular mortality, particularly sudden cardiac death. In accordance to the above mentioned findings, as omega-3 fatty acids per se have a direct cardiovascular protective role, our paper hypothesized that omega-3 fatty acids supplementation in ASD patients treated with atypical antipsychotic drugs may reduce cardiac arrhythmias and hence sudden cardiac death.


2007 ◽  
Vol 94 (1-3) ◽  
pp. 375-376 ◽  
Author(s):  
Fulvio A. Scorza ◽  
Roberta M. Cysneiros ◽  
Esper A. Cavalheiro ◽  
Ricardo M. Arida ◽  
Marly de Albuquerque

PLoS ONE ◽  
2013 ◽  
Vol 8 (10) ◽  
pp. e78414 ◽  
Author(s):  
Andriy E. Belevych ◽  
Hsiang-Ting Ho ◽  
Radmila Terentyeva ◽  
Ingrid M. Bonilla ◽  
Dmitry Terentyev ◽  
...  

2010 ◽  
Vol 70 (3) ◽  
pp. 665-670 ◽  
Author(s):  
FA. Scorza ◽  
RM. Cysneiros ◽  
RM. Arida ◽  
VC. Terra ◽  
HR. Machado ◽  
...  

People with epilepsy have an increased risk of dying prematurely and the most common epilepsy-related category of death is sudden unexpected death in epilepsy (SUDEP). SUDEP is mainly a problem for patients with chronic uncontrolled epilepsy. The ultimate goal of research in SUDEP is to develop new methods to prevent it and actions other than medical and surgical therapies that could be very useful. Nutritional aspects, i.e., omega-3 fatty acids deficiency, could have an interesting role in this scenario. Some animal and clinical studies have suggested that omega-3 fatty acids could be useful in the prevention and treatment of epilepsy and hence SUDEP. It has been ascertained that the only foods that provide large amounts of omega-3 are seafood (fish and shellfish); however, some fish are contaminated with methylmercury, which may counteract the positive effects of omega-3 fatty acids. Our update review summarises the knowledge of the role of fish consumption on epilepsy research.


2010 ◽  
Author(s):  
Fulvio Scorza ◽  
Esper Cavalheiro ◽  
Ricardo Arida ◽  
Vera Terra ◽  
Carla Scorza ◽  
...  

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