Identification of peripheral arterial disease in diabetic patients and its association with quality of life, physical activity and body composition

BACKGROUND: Diabetes mellitus (DM) is a risk factor for peripheral arterial disease (PAD). Neither the prevalence of PAD in type 2 (T2) DM nor its detrimental effects on quality of life (QoL) or physical activity (PA) have been well described in the Brazilian population. OBJECTIVES: To evaluate the prevalence of newly diagnosed PAD and its associations with QoL, PA and body composition in a sample of T2DM patients from a University Hospital. METHODS: Seventy-three (73) T2DM patients without previous diagnoses of major complications related to T2DM were enrolled. PAD was assessed using the ankle-brachial index (ABI); QoL was measured using a translated and validated SF-36 questionnaire; PA was measured using a modified Baecke questionnaire; and body composition was measured by segmental multi-frequency bioelectrical impedance. RESULTS: PAD prevalence was 13.7%, predominantly of mild severity (ABI between 0.8-0.9). The ABI results correlated with age (ρ=-0.26, P=0.03), DM duration (ρ=-0.28, P=0.02) and systolic and diastolic blood pressure (ρ=-0.33, P=0.007 and ρ=-0.28, P=0.02; respectively). Scores for the SF-36 physical component summary (PCS) were below the normal range, but no negative impact from PAD was identified by the PCS scores (normal-ABI 42.9±11.2 vs. PAD-ABI 38.12±11.07) or the Baecke PA results. Body composition analysis detected excessive body fat, especially in women, but there was no difference between groups. CONCLUSIONS: The prevalence of previously undiagnosed PAD in this population of T2DM patients was 13.7%, predominantly mild and asymptomatic forms, and was not yet associated with worsened QoL, PA levels or body composition variables.

Download Full-text

Nutritional status and body composition in patients with peripheral arterial disease: A cross-sectional examination of disease severity and quality of life

Ecology of Food and Nutrition ◽

10.1080/03670244.2015.1072817 ◽

2015 ◽

Vol 55 (1) ◽

pp. 87-109 ◽

Cited By ~ 4

Author(s):

Diana P. Brostow ◽

Alan T. Hirsch ◽

Mark A. Pereira ◽

Robin L. Bliss ◽

Mindy S. Kurzer

Keyword(s):

Quality Of Life ◽

Body Composition ◽

Peripheral Arterial Disease ◽

Nutritional Status ◽

Disease Severity ◽

Arterial Disease ◽

Cross Sectional ◽

Peripheral Arterial

Download Full-text

Cardiac rehabilitation in patients with peripheral arterial disease after revascularization

Vascular ◽

10.1177/1708538120945530 ◽

2020 ◽

pp. 170853812094553

Author(s):

Farhad Sami ◽

Sagar Ranka ◽

Matthew Lippmann ◽

Brian Weiford ◽

Kirk Hance ◽

...

Keyword(s):

Quality Of Life ◽

Peripheral Arterial Disease ◽

Cardiac Rehabilitation ◽

Arterial Disease ◽

Control Group ◽

Life Questionnaire ◽

Sf 36 ◽

Peripheral Arterial ◽

Change In Mean

Objectives To evaluate safety, feasibility, and benefit of cardiac rehabilitation (CR) in patients with peripheral arterial disease (PAD) who undergo revascularization. Methods We conducted a prospective, non-randomized, pilot study to assess the feasibility, safety, and benefit of CR in PAD patients after revascularization compared to standard of care (controls). CR feasibility was assessed by the ability to complete 36 sessions. Safety was defined as the absence of adverse cardiovascular events during CR. Quality of life (QoL) assessment was performed using SF-36 form (Medical Outcomes Study 36-Item Short-Form Health Survey) and PAD-specific quality of life questionnaire (VascuQOL6). Other endpoints included incidence of claudication during 6-minute walk test (6MWT), mean distance, and number of laps walked. All outcome data were collected before and after CR completion. Standard statistical tests were used for comparisons. Results This study enrolled 20 subjects (CR group = 10). Mean age was 60.70 (±7.13) and 63.1 (±9.17) years in CR and controls, respectively ( p-value > 0.05). Fifty percent and 60% were female in CR and control group, respectively. All subjects completed 36 CR sessions without adverse events. The increase in mean distance walked during 6MWT was higher in the CR group compared to control group (63.7 m vs. 10.5 m, p = 0.043). Change in mean number of laps walked was higher in the CR group (3.5 vs. –1.1; p < 0.01). Scores on 6 of 8 scales of SF-36 and VascuQOL6 were higher in the CR group, though not statistically significant. Conclusion CR is safe, feasible, and improves walking ability in ambulatory patients with PAD after arterial revascularization.

Download Full-text

Quality of life in elderly diabetic patients with peripheral arterial disease

Geriatrics and Gerontology International ◽

10.1111/j.1447-0594.2012.00928.x ◽

2012 ◽

Vol 13 (2) ◽

pp. 443-450 ◽

Cited By ~ 12

Author(s):

Moatassem S Amer ◽

Mohamad A Alsadany ◽

Mohammad F Tolba ◽

Omar H Omar

Keyword(s):

Quality Of Life ◽

Peripheral Arterial Disease ◽

Arterial Disease ◽

Diabetic Patients ◽

Peripheral Arterial

Download Full-text

Comparison of Generic and Disease-Specific Questionnaires for the Assessment of Quality of Life in Patients With Peripheral Arterial Disease

Yearbook of Vascular Surgery ◽

10.1016/s0749-4041(08)70167-2 ◽

2006 ◽

Vol 2006 ◽

pp. 216-217

Author(s):

G.L. Moneta

Keyword(s):

Quality Of Life ◽

Peripheral Arterial Disease ◽

Arterial Disease ◽

Peripheral Arterial ◽

Disease Specific

Download Full-text

Quality of Life Among Lower Extremity Peripheral Arterial Disease Patients who have Undergone Endovascular or Surgical Revascularization: A Case-control Study

Yearbook of Vascular Surgery ◽

10.1016/j.yvas.2011.06.022 ◽

2011 ◽

Vol 2011 ◽

pp. 206-207

Author(s):

N. Singh

Keyword(s):

Quality Of Life ◽

Peripheral Arterial Disease ◽

Lower Extremity ◽

Case Control Study ◽

Arterial Disease ◽

Case Control ◽

Surgical Revascularization ◽

Peripheral Arterial ◽

Control Study

Download Full-text

Saving more lives and limbs: applying a cardiac rehabilitation model of structured exercise to symptomatic peripheral arterial disease

British Journal of Cardiac Nursing ◽

10.12968/bjca.2020.0086 ◽

2021 ◽

pp. 1-8

Author(s):

Susan Matthews ◽

Martin Fox ◽

Sarah Coy ◽

Jane Whittaker ◽

Gail Brough ◽

...

Keyword(s):

Quality Of Life ◽

Blood Pressure ◽

Peripheral Arterial Disease ◽

Cardiac Rehabilitation ◽

Intermittent Claudication ◽

Arterial Disease ◽

Morbidity And Mortality ◽

Supervised Exercise ◽

Peripheral Arterial

Background/Aims Peripheral arterial disease is common among those aged 60 years or above and can cause debilitating intermittent claudication. This impacts quality of life and is a marker for increased morbidity and mortality, mainly from cardiovascular disease. Access to recommended exercise programmes for people with symptomatic peripheral arterial disease is poor in most areas of the UK. This study aimed to evaluate the benefits of expanding an established cardiac rehabilitation service to accommodate supervised exercise for people with peripheral arterial disease Methods The study evaluated 11 participants peripheral arterial disease and intermittent claudication who were referred by the Manchester leg circulation service. Participants underwent the programme involving eight weekly 1.5 hour sessions of supervised exercise and cardiovascular education with support, reassurance and motivation. The participants' blood pressure, walking impairment, quality of life, anxiety and depression were monitored and reviewed. Results Overall, the participants' walking distance, intermittent claudication, quality of life and blood pressure had improved. The participants' overall satisfaction with the programme was excellent. The programme also demonstrated clinical and cost-effectiveness. Conclusions A structured, supervised exercise programme can have considerable benefits for people with peripheral arterial disease, improving their symptoms and quality of life. It may also help to reduce the morbidity and mortality risks associated with inactivity in this patient group.

Download Full-text