scholarly journals Reference values for pulmonary volumes by plethysmography in a Brazilian sample of white adults

2019 ◽  
Vol 45 (3) ◽  
Author(s):  
Thamine Lessa ◽  
Carlos Alberto de Castro Pereira ◽  
Maria Raquel Soares ◽  
Renato Matos ◽  
Virgínia Pacheco Guimarães ◽  
...  

ABSTRACT Objective: To derive reference values for healthy white Brazilian adults who have never smoked and to compare the obtained values with reference values derived by Crapo and by Neder. Methods: Reference equations by quantile regressions were derived in 122 men and 122 women, non-obese, living in seven cities in Brazil. Age ranged from 21 to 92 years in women and from 25 to 88 years in men. Lung function tests were performed using SensorMedics automated body plethysmographies according ATS/ERS recommendations. Lower and upper limits were derived by specific equations for 5 and 95 percentiles. The results were compared to those suggested by Crapo in 1982, and Neder in 1999. Results: Median values for total lung capacity (TLC) were influenced only by stature in men, and by stature and age in women. Residual volume was influenced by age and stature in both genders. Weight was directly related to inspiratory capacity and inversely with functional residual capacity and expiratory reserve volume in both genders. A comparison of observed TLC data with values predicted by Neder equations showed significant lower values by the present data. Mean values were similar between data from present study and those derived by Crapo. Conclusion: New predicted values for lung volumes were obtained in a sample of white Brazilians. The values differ from those derived by Neder, but are similar to those derived by Crapo.

2018 ◽  
Vol 44 (6) ◽  
pp. 449-455 ◽  
Author(s):  
Tarciane Aline Prata ◽  
Eliane Mancuzo ◽  
Carlos Alberto de Castro Pereira ◽  
Silvana Spíndola de Miranda ◽  
Larissa Voss Sadigursky ◽  
...  

ABSTRACT Objective: To derive reference equations for spirometry in healthy Black adult never smokers in Brazil, comparing them with those published in 2007 for White adults in the country. Methods: The examinations followed the standards recommended by the Brazilian Thoracic Association, and the spirometers employed met the technical requirements set forth in the guidelines of the American Thoracic Society/European Respiratory Society. The lower limits were defined as the 5th percentile of the residuals. Results: Reference equations and limits were derived from a sample of 120 men and 124 women, inhabitants of eight Brazilian cities, all of whom were evaluated with a flow spirometer. The predicted values for FVC, FEV1, FEV1/FVC ratio, and PEF were better described by linear equations, whereas the flows were better described by logarithmic equations. The FEV1 and FVC reference values derived for Black adults were significantly lower than were those previously derived for White adults, regardless of gender. Conclusions: The fact that the predicted spirometry values derived for the population of Black adults in Brazil were lower than those previously derived for White adults in the country justifies the use of an equation specific to the former population.


2014 ◽  
Vol 40 (4) ◽  
pp. 397-402 ◽  
Author(s):  
Carlos Alberto de Castro Pereira ◽  
Andrezza Araujo Oliveira Duarte ◽  
Andrea Gimenez ◽  
Maria Raquel Soares

OBJECTIVE: To evaluate the spirometry values predicted by the 2012 Global Lung Function Initiative (GLI) equations, which are recommended for international use, in comparison with those obtained for a sample of White adults used for the establishment of reference equations for spirometry in Brazil. METHODS: The sample comprised 270 and 373 healthy males and females, respectively. The mean differences between the values found in this sample and the predicted values calculated from the GLI equations for FVC, FEV1, and VEF1/FVC, as well as their lower limits, were compared by paired t-test. The predicted values by each pair of equations were compared in various combinations of age and height. RESULTS: For the males in our study sample, the values obtained for all of the variables studied were significantly higher than those predicted by the GLI equations (p < 0.01 for all). These differences become more evident in subjects who were shorter in stature and older. For the females in our study sample, only the lower limit of the FEV1/FVC ratio was significantly higher than that predicted by the GLI equation. CONCLUSIONS: The predicted values suggested by the GLI equations for White adults were significantly lower than those used as reference values for males in Brazil. For both genders, the lower limit of the FEV1/FVC ratio is significantly lower than that predicted by the GLI equations.


1961 ◽  
Vol 16 (1) ◽  
pp. 27-29 ◽  
Author(s):  
Francisco Moreno ◽  
Harold A. Lyons

The changes produced by body posture on total lung capacity and its subdivisions have been reported for all positions except the prone position. Twenty normal subjects, twelve males and eight females, had determinations of total lung capacity in the three body positions, sitting, supine and prone. Tidal volume, minute ventilation and O2 consumption were also measured. The changes found on assumption of the supine position from the sitting position were similar to those previously reported. For the prone position, a smaller inspiratory capacity and a larger expiratory reserve volume were found. The mean values were changed, respectively, –8% and +37%. Associated with these changes was a significant increase of the functional residual capacity by 636 ml. Ventilation did not change significantly from that found during sitting, unlike the findings associated with the supine position, in which position the tidal volume was decreased. Respiratory frequency remained the same for all positions. Submitted on April 5, 1960


2015 ◽  
Vol 14 (2) ◽  
pp. 187-194 ◽  
Author(s):  
Raíssa De Oliveira Borja ◽  
Tania Fernandes Campos ◽  
Diana Amélia de Freitas ◽  
Thalita Medeiros Fernandes de Macêdo ◽  
Waléria Cristina Miranda de Mendonça ◽  
...  

Introduction: Reference equations are used to predict normal values for maximal respiratory pressures. Objectives: To develop predictive equations for maximal respiratory pressure in children. Methods: A total of 144 healthy children, aged between 7 and 11 years, were assessed. Maximal inspiratory and expiratory pressures were assessed with a digital manovacuometer on top of residual volume and total lung capacity, respectively. Results: The variables sex, age and weight showed association with maximal inspiratory pressure, while maximal expiratory pressure, in addition to the aforementioned variables, also showed association with height. After regression analysis, only sex and age had an influence on the variability of inspiratory and expiratory pressures. Conclusions: The present study provides reference values and proposes two equation models that predict maximal respiratory pressure values among children aged between 7 and 11 years.


2016 ◽  
Vol 26 (3) ◽  
pp. 374
Author(s):  
Camila Isabel Santos Schivinski ◽  
Renata Maba Gonçalves ◽  
Tayná Castilho

Introduction: Reference values and equations show strong variability and regional differences, despite a well-established role of the assessment of respiratory muscle strength (RMS) in children, with the objective to follow up on diseases that affect the function of respiratory muscles and enable adequate growth and development. Objective: To describe reference values and prediction equations of maximal respiratory pressures for Brazilian children. Methods: Literature review was conducted using databases LILACS, MEDLINE and Science Direct, and descriptors established by DeCS of the Virtual Health Library: reference values, child, respiratory muscle strength, predictive equations and their respective synonyms in English. Results: Six clinical trials were carried out, which determined reference values for children in various Brazilian regions. There was a relationship among RMS values and other factors, such as age, height and body mass. However, there was a significant difference among the data in the Brazilian states and divergence among the predicted values. Conclusion: There is a consensus on the relationship among RMS, anthropometric factors and regional influences. The articles studied reported diverging predicted values and reference equations.


2019 ◽  
Vol 13 ◽  
Author(s):  
Joana Belo ◽  
Teresa Palmeiro ◽  
Iolanda Caires ◽  
Ana L. Papoila ◽  
Marta Alves ◽  
...  

Background: Spirometry is the single most important test for the evaluation of respiratory function. The results are interpreted by comparing measured data with predicted values previously obtained from a reference population. Reference equations for spirometry have been discussed previously. The aim of this study was to compare reference values based on National Health and Nutrition Assessment Survey (NHANES III), European Community of Steel and Coal (ECSC), and Global Lung Initiative (GLI) equations in an elderly sample population. Methods: Subjects from the Geriatric Study on Health Effects of Air Quality in elder care centres who met the inclusion criteria were enrolled. Spirometry was performed according to international guidelines. The forced vital capacity, forced expiratory volume in 1 s, and FEV1/FVC ratio were reported as percentages of the predicted value, and the lower limit of normality was calculated. Results: Out of 260 elderly patients, 69.6% were women; the mean age was 83.0 ± 6.46 years with an age range of 65– 95 years. The lowest %FVC and %FEV1 values were obtained using the GLI reference equations. However, when NHANES III equations were used, the FEV1/FVC ratio was higher than ratios obtained from GLI and ECSC equations. The prevalence of airway obstruction was highest using ECSC equations, while GLI equations demonstrated more restrictive defects. Conclusions: The present study showed meaningful differences in the reference values, and consequently, in the results obtained using NHANES III, ECSC,  and GLI reference equations. The spirometry interpretation was also influenced by the reference equations used.


2011 ◽  
Vol 5 (1) ◽  
pp. 157-161
Author(s):  
Ahmad H. Alghadir ◽  
Farag A. Aly

Abstract Background: Ethnic differences in lung function are recognized. However, most of the modern lung function equipments are pre-programmed with Caucasian reference values. Objective: Measure spirometric values among healthy Saudi male and female adults and compare with the Caucasian reference values in a standard spirometer. Methods: Thirty healthy Saudi young adults (15 males and 15 females; mean age 25 years) participated in this study. Forced vital capacity (FVC), forced expiratory volume in one second (FEV1), FEV1/FVC (%), and maximal voluntary ventilation (MVV) were recorded using a portable digital spirometer. Results: Mean values of FVC, FEV1, FEV1/FVC (%) and MVV for the Saudi subjects were significantly lower than the Caucasians predicted values. Conclusion: Interpretation of lung function tests of Saudi subjects based on the Caucasian prediction equations is generally not valid, as the parameters of lung function tests in Saudi subjects are lower than the Caucasian reference values. The present results underline an urgent need for larger studies to develop prediction equations based on normative spirometric values for Saudi population involving subjects of all ages and both genders living in different climates of the country.


PEDIATRICS ◽  
1959 ◽  
Vol 24 (2) ◽  
pp. 181-193
Author(s):  
C. D. Cook ◽  
P. J. Helliesen ◽  
L. Kulczycki ◽  
H. Barrie ◽  
L. Friedlander ◽  
...  

Tidal volume, respiratory rate and lung volumes have been measured in 64 patients with cystic fibrosis of the pancreas while lung compliance and resistance were measured in 42 of these. Serial studies of lung volumes were done in 43. Tidal volume was reduced and the respiratory rate increased only in the most severely ill patients. Excluding the three patients with lobectomies, residual volume and functional residual capacity were found to be significantly increased in 46 and 21%, respectively. These changes correlated well with the roentgenographic evaluation of emphysema. Vital capacity was significantly reduced in 34% while total lung capacity was, on the average, relatively unchanged. Seventy per cent of the 61 patients had a signficantly elevated RV/TLC ratio. Lung compliance was significantly reduced in only the most severely ill patients but resistance was significantly increased in 35% of the patients studied. The serial studies of lung volumes showed no consistent trends among the groups of patients in the period between studies. However, 10% of the surviving patients showed evidence of significant improvement while 15% deteriorated. [See Fig. 8. in Source Pdf.] Although there were individual discrepancies, there was a definite correlation between the clinical evaluation and tests of respiratory function, especially the changes in residual volume, the vital capacity, RV/ TLC ratio and the lung compliance and resistance.


2000 ◽  
Vol 15 (2) ◽  
pp. 51-54
Author(s):  
Deborah Barr ◽  
Lee Van Dusen ◽  
Steve Ess ◽  
Julie Plezbert

This study examined pulmonary function of pipers and cardiac adaptation to the playing of the Great Highland bagpipe. Pipers (n = 13) of varying ages (31-65 years) and playing experiences (2-20+ years) were evaluated for vital capacity (VC), maximal voluntary ventilation (MVV), and forced vital capacity (FVC) using a RIKO AS-600 spirometer. Subjects were monitored by impedance cardiograph for heart rate (HR), stroke volume (SV), and cardiac output (CO) at rest and during 5 minutes of playing. An automatic blood pressure (BP) monitor collected BP values over the same time period. Eleven weeks after initial cardiac data collection, the BP and cardiac measurements were repeated using the same protocols. Mean values for HR, SV, and CO were calculated for rest and each minute (1-5) of playing. A 2 (data session) by 6 (rest, min 1–5) repeated-measures ANOVA was performed. Analysis revealed a significant overall time effect (p < 0.001) on HR. A-priori contrast comparing all playing times with rest showed significant differences at all time points. Analysis of SV and CO failed to find significance. Heart rate values calculated for percent of maximum ranged from 68% to 89% of maximum overall while playing (session 1) and from 55% to 81% of maximum (session 2). Predicted percent of maximum values for VC and MVV found 77% of players above their maximum predicted values.


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