scholarly journals Epidemiological profile of acute kidney injury in critically ill patients admitted to intensive care units: A Prospective Brazilian Cohort

2021 ◽  
Author(s):  
Antônio José Inda-Filho ◽  
Heitor Siqueira Ribeiro ◽  
Edilene Almeida Vieira ◽  
Aparecido Pimentel Ferreira
Keyword(s):  
Acute Kidney Injury ◽  
Intensive Care ◽  
Intensive Care Units ◽  
Meta Analysis ◽  
Kidney Injury ◽  
Federal District ◽  
Incidence And Mortality ◽  
Epidemiological Profile ◽  
Stage 1 ◽  
Disease Stages

Abstract Introduction Acute kidney injury (AKI) is a frequent syndrome affecting patients admitted to intensive care units (ICU), and it is associated with poor clinical outcomes. The aim of the present study was to understand the epidemiological profile of patients with AKI admitted to ICUs. Methods Prospective cohort study, carried out in three ICUs in the Federal District, Brazil. Between October/2017 and December/2018, 8,131 patients were included in the cohort. AKI was defined according to the KDIGO criteria. The main outcomes assessed were AKI development and mortality within 28 days of hospitalization. Results Of the 8,131 patients followed up, 1,728 developed AKI (21.3%). Of the 1,728 patients with AKI, 1,060 (61.3%) developed stage 1, while stages 2 and 3 represented 154 (8.9%) and 514 (29.7%), respectively. Of these, 459 (26.6%) underwent renal replacement therapy. The mortality was 25.7% for those with AKI, and 4.9% for those without AKI. Discussion Patients with AKI had higher mortality rates when compared to those without AKI. Likewise, among patients with AKI, higher disease stages were associated with higher death occurrences. AKI incidence (21.3%) and mortality (25.7%) in our study is in line with the largest meta-analysis ever conducted, in which incidence and mortality of 21.6 and 23.9% were observed, respectively. These findings confirm the importance of establishing the KDIGO guideline for the definition and management of AKI in Brazilian ICUs.

scholarly journals A systematic review and meta-analysis of acute kidney injury in the intensive care units of developed and developing countries

PLoS ONE ◽  
2020 ◽  
Vol 15 (1) ◽  
pp. e0226325 ◽  
Author(s):  
Fernando de Assis Ferreira Melo ◽  
Etienne Macedo ◽  
Ana Caroline Fonseca Bezerra ◽  
Walédya Araújo Lopes de Melo ◽  
Ravindra L. Mehta ◽  
...  
Keyword(s):  
Systematic Review ◽  
Acute Kidney Injury ◽  
Developing Countries ◽  
Intensive Care ◽  
Intensive Care Units ◽  
Meta Analysis ◽  
Kidney Injury

Acute kidney injury in the elderly patients of Thai-surgical intensive care units (Thai-SICU) study

2017 ◽  
Vol 30 (2) ◽  
pp. 131
Author(s):  
Konlawij Trongtrakul ◽  
Sujaree Poopipatpab ◽  
Ploynapas Limphunudom ◽  
Chawika Pisitsak ◽  
Kaweesak chittawatanarat ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Intensive Care ◽  
Elderly Patients ◽  
Intensive Care Units ◽  
Kidney Injury ◽  
The Elderly ◽  
Surgical Intensive Care

scholarly journals Acute Kidney Injury in Patients Undergoing Cardiac Transplantation: A Meta-Analysis

Medicines ◽  
2019 ◽  
Vol 6 (4) ◽  
pp. 108 ◽  
Author(s):  
Charat Thongprayoon ◽  
Ploypin Lertjitbanjong ◽  
Panupong Hansrivijit ◽  
Anthony Crisafio ◽  
Michael Mao ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Mortality Risk ◽  
Cardiac Transplantation ◽  
Patient Survival ◽  
Meta Analysis ◽  
Solid Organ Transplantation ◽  
Kidney Injury ◽  
Solid Organ ◽  
Short Term ◽  
Incidence And Mortality

Background: Acute kidney injury (AKI) is a common complication following solid-organ transplantation. However, the epidemiology of AKI and mortality risk of AKI among patients undergoing cardiac transplantation is not uniformly described. We conducted this study to assess the incidence of AKI and mortality risk of AKI in adult patients after cardiac transplantation. Methods: A systematic review of EMBASE, MEDLINE, and Cochrane Databases was performed until June 2019 to identify studies evaluating the incidence of AKI (by standard AKI definitions), AKI requiring renal replacement therapy (RRT), and mortality risk of AKI in patients undergoing cardiac transplantation. Pooled AKI incidence and mortality risk from the included studies were consolidated by random-effects model. The protocol for this study is registered with PROSPERO (no. CRD42019134577). Results: 27 cohort studies with 137,201 patients undergoing cardiac transplantation were identified. Pooled estimated incidence of AKI and AKI requiring RRT was 47.1% (95% CI: 37.6–56.7%) and 11.8% (95% CI: 7.2–18.8%), respectively. The pooled ORs of hospital mortality and/or 90-day mortality among patients undergoing cardiac transplantation with AKI and AKI requiring RRT were 3.46 (95% CI, 2.40–4.97) and 13.05 (95% CI, 6.89–24.70), respectively. The pooled ORs of 1-year mortality among patients with AKI and AKI requiring RRT were 2.26 (95% CI, 1.56–3.26) and 3.89 (95% CI, 2.49–6.08), respectively. Conclusion: Among patients undergoing cardiac transplantation, the incidence of AKI and severe AKI requiring RRT are 47.1% and 11.8%, respectively. AKI post cardiac transplantation is associated with reduced short term and 1-year patient survival.

Survival and renal recovery after acute kidney injury requiring dialysis outside of intensive care units

2020 ◽  
Vol 52 (12) ◽  
pp. 2367-2377
Author(s):  
Silvia González Sanchidrián ◽  
Javier L. Deira Lorenzo ◽  
M. Jimena Muciño Bermejo ◽  
Pedro J. Labrador Gómez ◽  
Juan R. Gómez-Martino Arroyo ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Intensive Care ◽  
Intensive Care Units ◽  
Kidney Injury ◽  
Renal Recovery

scholarly journals Nursing Activities Score and Acute Kidney Injury

2017 ◽  
Vol 70 (3) ◽  
pp. 475-480 ◽  
Author(s):  
Filipe Utuari de Andrade Coelho ◽  
Mirian Watanabe ◽  
Cassiane Dezoti da Fonseca ◽  
Katia Grillo Padilha ◽  
Maria de Fátima Fernandes Vattimo
Keyword(s):  
Intensive Care Unit ◽  
Acute Kidney Injury ◽  
Intensive Care ◽  
Kidney Disease ◽  
Quantitative Study ◽  
Kidney Injury ◽  
Nursing Workload ◽  
Intensive Care Patients ◽  
Stage 1

ABSTRACT Objective: to evaluate the nursing workload in intensive care patients with acute kidney injury (AKI). Method: A quantitative study, conducted in an intensive care unit, from April to August of 2015. The Nursing Activities Score (NAS) and Kidney Disease Improving Global Outcomes (KDIGO) were used to measure nursing workload and to classify the stage of AKI, respectively. Results: A total of 190 patients were included. Patients who developed AKI (44.2%) had higher NAS when compared to those without AKI (43.7% vs 40.7%), p <0.001. Patients with stage 1, 2 and 3 AKI showed higher NAS than those without AKI. A relationship was identified between stage 2 and 3 with those without AKI (p = 0.002 and p <0.001). Conclusion: The NAS was associated with the presence of AKI, the score increased with the progression of the stages, and it was associated with AKI, stage 2 and 3.

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