scholarly journals The use of bisphosphonates does not contraindicate orthodontic and other types of treatment!

2014 ◽  
Vol 19 (4) ◽  
pp. 18-26
Author(s):  
Alberto Consolaro
Keyword(s):  
Personal Experience ◽  
Dental Treatment ◽  
Case Reports ◽  
Scientific Evidence ◽  
Mechanisms Of Action ◽  
Bone Diseases ◽  
Accurate Assessment ◽  
Clinical Knowledge ◽  
Bone Biology ◽  
Professional Opinion

Bisphosphonates have been increasingly used not only to treat bone diseases as well as conditions such as osteopenia and osteoporosis, but also in oncotherapy. The use of bisphosphonates induces clinicians to fear and care. These reactions are associated with controversy resulting from lack of in-depth knowledge on the mechanisms of action as well as lack of a more accurate assessment of side effects. Scientific and clinical knowledge disclosure greatly contributes to professionals' discernment and inner balance, especially orthodontists. Fear does not lead to awareness. For these reasons, we present an article that focuses on that matter. This article was adapted from different journals of different dental specialties, as mentioned on footnote. There is no scientific evidence demonstrating that bisphosphonates are directly involved with etiopathogenic mechanisms of osteonecrosis and jaw osteomyelitis. Their use is contraindicated and limited in cases of dental treatment involving bone tissue. Nevertheless, such fact is based on professional opinion, case reports, and personal experience or experiment trials with failing methods. Additional studies will always be necessary; however, in-depth knowledge on bone biology is of paramount importance to offer an opinion about the clinical use of bisphosphonates and their further implications. Based on bone biopathology, this article aims at contributing to lay the groundwork for this matter.

So Much Writing, So Little Science: A Review of 37 Years of Literature on Edetate Sodium Chelation Therapy

1993 ◽  
Vol 27 (12) ◽  
pp. 1504-1509 ◽  
Author(s):  
Michael T. Grier ◽  
David G. Meyers
Keyword(s):  
Clinical Trials ◽  
Clinical Practice ◽  
Literature Search ◽  
Chelation Therapy ◽  
Case Reports ◽  
Scientific Evidence ◽  
Case Series ◽  
Mechanisms Of Action ◽  
Tetraacetic Acid ◽  
Safety And Efficacy

OBJECTIVE: To determine the safety and efficacy of edetate sodium (ethylenediamine tetraacetic acid; EDTA) chelation therapy for atherosclerosis. METHODS: Literature search using MEDLINE, encompassing 1966 through May 1993. Further references were obtained from articles and books, and from citations obtained from the American Academy of Medical Preventics. RESULTS: 16 case reports or case series, 2 longitudinal studies, and 3 clinical trials were reviewed, along with testimonials cited in 19 books. CONCLUSIONS: Little valid scientific evidence is available. Although the postulated mechanisms of action for EDTA are biologically plausible and EDTA appears to be safe, it has not been proven effective. Indeed, the best evidence shows it to be ineffective. Therefore, EDTA chelation therapy should not be used in clinical practice to treat atherosclerosis.

scholarly journals Management of lymphoma in pregnancy

2009 ◽  
Vol 2 (2) ◽  
pp. 46-51 ◽  
Author(s):  
K Hodby ◽  
P A Fields
Keyword(s):  
Health Care Professionals ◽  
Personal Experience ◽  
Best Practice ◽  
Current Practice ◽  
Case Reports ◽  
Current Opinion ◽  
Diagnosis Of Cancer ◽  
Relative Rarity ◽  
The Impact ◽  
Common Malignancy

One in every thousand pregnancies is complicated by a concurrent diagnosis of cancer. Lymphoma is currently the fourth most common malignancy diagnosed during pregnancy and its incidence is rising. The diagnosis and management of any malignancy during pregnancy is clearly a clinical and emotional minefield for both patients and health-care professionals. The major challenge is to optimize medical treatment offered to the mother, while limiting the impact on the fetus. Given the relative rarity of the situation, current practice is guided by case reports and personal experience of management of similar patients. Our centre has a large and busy lymphoma practice, and has cared for several women diagnosed with a variety of subtypes of lymphoma over the years. This review aims to summarize current opinion about best practice regarding these patients and discusses options available from the current literature.

scholarly journals A Clinical Perspective of Low Carbohydrate Ketogenic Diets: A Narrative Review

2021 ◽  
Vol 8 ◽  
Author(s):  
Samir Giuseppe Sukkar ◽  
Maurizio Muscaritoli
Keyword(s):  
Case Reports ◽  
Scientific Evidence ◽  
Experimental Models ◽  
Narrative Review ◽  
Caloric Content ◽  
Beneficial Effects ◽  
Cellular Processes ◽  
Positive Effects ◽  
Ketogenic Diets ◽  
Morbid Conditions

Low carbohydrates diets (LCDs), which provide 20–120 g of carbohydrates per day, have long been used as therapeutic options in the treatment of severe obesity, type 2 diabetes mellitus and other morbid conditions, with good results in terms of weight loss and control of the main metabolic parameters, at least in the short and medium term. According to the caloric content and the macronutrient composition, we can classify LCDs in hypocaloric, normoproteic diets [such as the Very Low-Calorie Ketogenic Diet (VLCKD) or the protein-sparing modified fasting (PSMF)], hypocaloric, hyperproteic and hyperlipidic diets (e.g., Atkins, Paleo diets…) and normocaloric, normo-/hyperproteic diets (eucaloric KD), the latter mainly used in patients with brain tumors (gliomas) and refractory epilepsy. In addition to LCD diets, another interesting dietary approach which gained attention in the last few decades is fasting and its beneficial effects in terms of modulation of metabolic pathways, cellular processes and hormonal secretions. Due to the impossibility of using fasting regimens for long periods of time, several alternative strategies have been proposed that can mimic the effects, including calorie restriction, intermittent or alternating fasting, and the so-called fasting mimicking diets (FMDs). Recent preclinical studies have shown positive effects of FMDs in various experimental models of tumors, diabetes, Alzheimer Disease, and other morbid conditions, but to date, the scientific evidence in humans is limited to some opens studies and case reports. The purpose of our narrative review is to offer an overview of the characteristics of the main dietary regimens applied in the treatment of different clinical conditions as well as of the scientific evidence that justifies their use, focusing on low and zero-carb diets and on the different types of fasting.

Mechanisms of action of spa therapies in rheumatic diseases: what scientific evidence is there?

2010 ◽  
Vol 31 (1) ◽  
pp. 1-8 ◽  
Author(s):  
Antonella Fioravanti ◽  
Luca Cantarini ◽  
Giacomo Maria Guidelli ◽  
Mauro Galeazzi
Keyword(s):  
Rheumatic Diseases ◽  
Scientific Evidence ◽  
Mechanisms Of Action

Acupuncture in the Management of Anxiety Related to Dental Treatment: A Case Series

2010 ◽  
Vol 28 (1) ◽  
pp. 3-5 ◽  
Author(s):  
Palle Rosted ◽  
Mads Bundgaard ◽  
Sian Gordon ◽  
Anne Marie Lynge Pedersen
Keyword(s):  
Acupuncture Treatment ◽  
Dental Treatment ◽  
Case Reports ◽  
Dental Anxiety ◽  
Case Series ◽  
Randomised Clinical Trial ◽  
Common Phenomenon ◽  
Inexpensive Method ◽  
Before And After ◽  
Severe Anxiety

Background Anxiety related to dental treatment is a common phenomenon that has a significant impact on the provision of appropriate dental care. The aim of this case series was to examine the effect of acupuncture given prior to dental treatment on the level of anxiety. Methods Eight dentists submitted 21 case reports regarding the treatment of dental anxiety. The level of anxiety was assessed by the Beck Anxiety Inventory (BAI). Only patients with moderate to severe anxiety (BAI score ≥16) were included. The remaining 20 patients, 16 women and 4 men, with a mean age of 40.3 years, had a median BAI score of 26.5 at baseline. The BAI score was assessed before and after the acupuncture treatment. All patients received acupuncture treatment for 5 min prior to the planned dental treatment using the points GV20 and EX6. Results There was a significant reduction in median value of BAI scores after treatment with acupuncture (26.5 reduced to 11.5; p<0.01), and it was possible to carry out the planned dental treatment in all 20 cases after acupuncture treatment. Previously this had only been possible in six cases. Conclusion Acupuncture prior to dental treatment has a beneficial effect on the level of anxiety in patients with dental anxiety and may offer a simple and inexpensive method of treatment. However, the present results need to be tested in a larger randomised clinical trial in order to evaluate the effectiveness of the acupuncture treatment in patients with dental anxiety.

Dental care of patients scheduled for cardiovascular surgery: which protocols to follow?

2021 ◽  
pp. 1-7
Author(s):  
Farhan Raza Khan ◽  
Humayun Kaleem Siddiqui ◽  
Muhammad Tariq Khan
Keyword(s):  
Infective Endocarditis ◽  
Cardiovascular Surgery ◽  
Dental Treatment ◽  
Scientific Evidence ◽  
Real Life ◽  
Cardiac Operation ◽  
Valvular Surgery ◽  
Dental Procedures ◽  
Life Challenges ◽  
Cardiac Operations

Abstract Dental extraction of abscessed or infected teeth before cardiac operation is frequently advocated to lower the risk of infections especially infective endocarditis. The scientific evidence that supports dental procedures before cardio-valvular surgery is however limited. The aim of the present paper was to explore whether there are any protocols for patients needing dental treatment before cardiac operations. Moreover, we have discussed the real life challenges encountered in the management of such patients. Continuous....

Appartenenza e separazione nelle terapie del lutto: da un tempo bloccato alla presenza di un'assenza

2009 ◽  
pp. 5-21
Author(s):  
Anna Maria Rapone ◽  
Trasarti Wilma Sponti
Keyword(s):  
Personal Experience ◽  
Case Reports ◽  
Personal Resources ◽  
Past Century ◽  
Urban Context ◽  
Private Space ◽  
Death And Loss

- Rituals, of past century culture, allowed grieving to be socially expressed, thus facilitating its condivision and elaboration. Now day culture, in occidental urban context, often leaves in a private space, psychotherapy, the expression of it. The authors, from their personal experience of psychotherapists and teachers, individuate in block of time and in a blocking of grieving a possible source of psychopathology. Aim of this article is to offer a few points of reflection on the theme of grieving for a wider understanding and utilization of it. Then they suggest the concept of loyalty, resilience, together with the concept of pacing, to accept death and loss in an isomorphic possibility of individuation and personal resources utilization. The elaboration of grief can then evolve in a nurturing way. Case reports illustrate their experience on grief elaboration.

Dry needling for scar treatment

2020 ◽  
Vol 38 (6) ◽  
pp. 435-439
Author(s):  
Evgeni Rozenfeld ◽  
Eleanora Sapoznikov Sebakhutu ◽  
Yuval Krieger ◽  
Leonid Kalichman
Keyword(s):  
Wound Healing ◽  
Case Reports ◽  
Healing Process ◽  
Preliminary Evidence ◽  
Mechanisms Of Action ◽  
Wound Healing Process ◽  
Dry Needling ◽  
Physiological Mechanisms ◽  
Positive Effects ◽  
Intervention Protocol

Objective: To review current scientific knowledge as to the efficacy of dry needling of scars on pain and other related symptoms and explore the possible physiological mechanisms of action. Methods: A narrative review of scientific literature published in English. Results: Two randomized controlled trials found that dry needling of scars (using the classic “surrounding the dragon” technique in one study and intradermal needling in a second study) was more effective than sham or control interventions with respect to scar appearance and pain. Two case reports have suggested that scar needling generates a rapid decrease in pain and improvement of mobility in scarred tissues. Another two case reports have reported positive effects of scar needling on the wound healing process. These findings are supported by an animal study examining the effect of needling on the wound healing process and the physiological mechanisms of action underlying the technique. Conclusion: There is preliminary evidence that the “surrounding the dragon” needling technique is a beneficial treatment for patients suffering from scar pain and other scar-related symptoms and can facilitate wound healing and make this process less painful. Further high-quality studies should be conducted to verify/quantify the efficacy of this method, to better understand the underlying mechanisms of action underlying the effects of scar needling and to establish an effective intervention protocol.

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