scholarly journals Staphylococcus aureus and the oxacillin sensitivity profile in hospitalized people with HIV/AIDS

2016 ◽  
Vol 50 (4) ◽  
pp. 617-621
Author(s):  
Daiana Patrícia Marchetti Pio ◽  
Lilian Andreia Fleck Reinato ◽  
Letícia Pimenta Lopes ◽  
Elucir Gir

Abstract Objective Analyze nasal colonization by oxacillin-sensitive and oxacillin-resistant Staphylococcus aureus in people with HIV/AIDS (PWHA) at days 1 and7 of hospitalization. METHOD A prospective observational study conducted in a hospital in the countryside of the state of São Paulo. Nasal swab samples were collected and analyzed through microbiological identification, at days 1 and 7 of hospitalization of PWHA, between August 2011 and January 2014. Data were analyzed via IBM SPSS(r), version 20.0. RESULTS Nasal secretion samples were collected from 187 (50.1%) PWHA at days 1 and 7 of hospitalization. Of these, Staphylococcus aureus was identified in 64 (34.2%) PWHA. CONCLUSION At day 1 of hospitalization, 27 PWHA were identified with Staphylococcus aureus; 27 PWHA presented colonization by Staphylococcus aureus at days 1 and 7, and 10 PWHA only at day 7. Of 64 PWHA colonized by Staphylococcus aureus, the susceptibility profile of isolated Staphylococcus aureus was oxacillin-resistant in 25 PWHA.

2011 ◽  
Vol 3 (3) ◽  
pp. 361-374
Author(s):  
Marcos Livato ◽  
Gideon Carvalho de Benedicto

The new "molds" of competitiveness have suggested that the attentions should be focused on an efficient management of the supply chain in the supermarket departments, starting from the producer until the end user of the products, reducing the operational costs. It's known that the elimination of some of these stages of intermediation of the ways of distribution can represent to the small and mediums retailers an important competitive advantage, with the elimination of the additional costs charged by the intermediaries. The objective of this work is to propose a model of restructuring  of the ways of distribution in the brazilian retail of  food through of the strategy, inducing the elimination of the intermediaries. The search of the bibliography was used like basement to the definition of the methodology of this search, that was realized through of an observational study realized with nineteen Central Business Supermarket s in the state of São Paulo. To do the collection of the datas was prepared a questionary with specific questions. After the collection of the datas and tab, were used techniques quantitive  of analysis of datas through of SAS system. The study intends to discuss the proposal of the cooperation's networks like a strategic alternative, with the possibility of elimination of some phases of intermediation of the distribuition's ways.


Author(s):  
SQ Rocha ◽  
SR Silva ◽  
DL Estevam ◽  
MV Tancredi ◽  
RA Souza ◽  
...  
Keyword(s):  

2021 ◽  
Vol 15 (9) ◽  
pp. e0009704
Author(s):  
Ranjani Somayaji ◽  
Viriya Hantrakun ◽  
Prapit Teparrukkul ◽  
Gumphol Wongsuvan ◽  
Kristina E. Rudd ◽  
...  

Background Community acquired bacteremia (CAB) is a common cause of sepsis in low and middle-income countries (LMICs). However, knowledge about factors associated with outcomes of CAB in LMICs is limited. Methodology/Principal findings A prospective observational study (Ubon-sepsis) of adults admitted to a referral hospital with community-acquired infection in Northeastern Thailand was conducted between March 1, 2013 and February 1, 2017. In the present analysis, patients with a blood culture collected within 24 hours of admission that was positive for one of the three most common pathogens were studied. Clinical features, management, and outcomes of patients with each cause of CAB were compared. Of 3,806 patients presenting with community-acquired sepsis, 155, 131 and 37 patients had a blood culture positive for Escherichia coli, Burkholderia pseudomallei and Staphylococcus aureus, respectively. Of these 323 CAB patients, 284 (89%) were transferred from other hospitals. 28-day mortality was highest in patients with B. pseudomallei bactaeremia (66%), followed by those with S. aureus bacteraemia (43%) and E. coli (19%) bacteraemia. In the multivariable Cox proportional hazards model adjusted for age, sex, transfer from another hospital, empirical antibiotics prior to or during the transfer, and presence of organ dysfunction on admission, B. pseudomallei (aHR 3.78; 95%CI 2.31–6.21) and S. aureus (aHR 2.72; 95%CI 1.40–5.28) bacteraemias were associated with higher mortality compared to E. coli bacteraemia. Receiving empirical antibiotics recommended for CAB caused by the etiologic organism prior to or during transfer was associated with survival (aHR 0.58; 95%CI 0.38–0.88). Conclusions/Significance Mortality of patients with CAB caused by B. pseudomallei was higher than those caused by S. aureus and E. coli, even after adjusting for presence of organ dysfunction on admission and effectiveness of empirical antibiotics received. Improving algorithms or rapid diagnostic tests to guide early empirical antibiotic may be key to improving CAB outcomes in LMICs.


2021 ◽  
Vol 15 (10) ◽  
pp. 1426-1435
Author(s):  
Loay Al Wahaibi ◽  
Rajaa Al Sudairi ◽  
Abdullah Balkhair ◽  
Huda Al-Awaisi ◽  
Mohamed Mabruk

Introduction: Methicillin-Resistant Staphylococcus aureus (MRSA) is a S. aureus strain characterized by resistance to cloxacillin. Healthcare workers (HCWs), are recognized for their heightened risk for MRSA acquisition and possibly for MRSA nosocomial transmission. This cross-sectional study aimed to determine the prevalence and the associated risk factors of MRSA colonization among healthcare workers at Sultan Qaboos University Hospital (SQUH) in Oman. Methodology: A total of 200 nasal swab samples were collected from the healthcare workers at SQUH during the period October 2nd 2018 to January 7th 2019. All nasal swab samples were examined microbiologically for the presence of MRSA using the standard method and the results were confirmed by detection of the mecA product (PBP2a). Data on associated risk factors for MRSA colonization was collected and analyzed. Results: Forty-one of the 200 screened healthcare workers (20.5%) were found to have nasal carriage of Staphylococcus aureus of which 63.4% were Methicillin Sensitive and 36.6% were Methicillin-Resistant (MRSA). Methicillin-Resistant Staphylococcus aureus (MRSA) was isolated from fifteen of the 200 screened healthcare workers giving a prevalence rate of nasal colonization with MRSA of 7.5%. We found no statistical association between healthcare worker MRSA nasal colonization and age, gender, HCWs specialty, hand hygiene practices, skin condition, previous MRSA infection, and previous exposure to antibiotics. Conclusions: Identification of the prevalence and the associated risk factors of MRSA colonization in healthcare workers mandates continuous surveillance and the implementation of all possible preventive measures to reduce re-occurrences.


2018 ◽  
Vol 11 (1) ◽  
Author(s):  
Cynthia Regina Pedrosa Soares ◽  
Celso Rodrigues de Lira ◽  
Maximiliano Alexandre H. Cunha ◽  
Valter Romão de Souza Junior ◽  
Fábio Lopes de Melo ◽  
...  

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