scholarly journals Experimental antegrade enema: effects on water, electrolyte and acid-base balances with different solutions

2007 ◽  
Vol 22 (5) ◽  
pp. 372-378 ◽  
Author(s):  
Laura Helman ◽  
José Luiz Martins ◽  
Djalma José Fagundes ◽  
Edward Esteves ◽  
Cirilo de Paula Lima ◽  
...  
Keyword(s):  
Metabolic Acidosis ◽  
Electrolyte Solution ◽  
Sodium Phosphate ◽  
Saline Solution ◽  
Isotonic Saline ◽  
Phosphate Solution ◽  
Acid Base ◽  
Glycerin Solution ◽  
Sodium Phosphate Solution ◽  
Antegrade Enema

PURPOSE: To study the effects on the water, electrolyte, and acid-base balances in rabbits submitted to antegrade enema with different solutions through appendicostomy. METHODS: Forty male New Zealand rabbits were submitted to appendicostomy, and distributed in 4 groups, according to the antegrade enema solution: PEG group, polyethylene glycol electrolyte solution (n=10); ISS group, isotonic saline solution (n=10); GS group, glycerin solution (n=10); SPS group, sodium phosphate solution (n=10). After being weighed, arterial blood gas analysis, red blood count, creatinine and electrolytes were measured at 4 times: preoperatively (T1); day 6 postop, before enema (T2); 4h after enema (T3); and 24h after T3 (T4). RESULTS: In PEG group occurred Na retention after 4h, causing alkalemia, sustained for 24h with HCO3 retention. In ISS group occurred isotonic water retention and hyperchloremic acidosis after 4h, which was partially compensated in 24h. GS group showed metabolic acidosis after 4h, compensated in 24h. In SPS group occurred hypernatremic dehydration, metabolic acidosis in 4h, and hypokalemia, hypocalcemia, hypomagnesemia, and metabolic alkalosis with partially compensated dehydration in 24h. CONCLUSIONS: All solutions used in this study caused minor alterations on water, electrolyte or acid-base balances. The most intense ones were caused by hypertonic sodium phosphate solution (SPS) and isotonic saline solution (ISS) and the least by polyethyleneglycol electrolyte solution (PEG) and glycerin solution 12% (GS).

scholarly journals Hyperchloremic metabolic acidosis during bipolar transurethral resection of the prostate: a report of two cases

2021 ◽  
Vol 49 (6) ◽  
pp. 030006052110244
Author(s):  
Ann Hee You ◽  
Ji Yoo Lee ◽  
Jeong-Hyun Choi ◽  
Mi Kyeong Kim
Keyword(s):  
Metabolic Acidosis ◽  
Transurethral Resection ◽  
Normal Saline ◽  
Isotonic Saline ◽  
Hemodynamic Instability ◽  
Acid Base ◽  
Electrolyte Disturbance ◽  
Irrigation Fluid ◽  
Laboratory Test Results ◽  
Hyperchloremic Metabolic Acidosis

Compared with monopolar transurethral resection of the prostate (TURP), which requires electrolyte-free irrigation fluid, normal saline can be used as the irrigation solution in bipolar and laser TURP. The risk of TURP syndrome and severe electrolyte disturbance is minimized when normal saline is used as the irrigation fluid. However, the use of isotonic saline also causes acid-base imbalance and electrolyte disturbance. We experienced two patients who developed hyperchloremic metabolic acidosis during bipolar TURP. After proper intervention, hemodynamic instability resolved, and laboratory test results normalized. Anesthesiologists must pay attention to acid-base and electrolyte status when rapid absorption of excessive isotonic solution is suspected, even during bipolar and laser TURP, which use normal saline as the irrigation fluid.

P23 Tolerability of prednisolone and dexamethasone in children in saudi arabia and the united kingdom

2018 ◽  
Vol 103 (2) ◽  
pp. e2.26-e2
Author(s):  
Fahad Aljebab ◽  
Mofadhi Alanazi ◽  
Imti Choonara ◽  
Sharon Conroy
Keyword(s):  
Saudi Arabia ◽  
Abdominal Pain ◽  
Sodium Phosphate ◽  
Oral Prednisolone ◽  
Phosphate Solution ◽  
List Type ◽  
Dexamethasone Sodium Phosphate ◽  
Significant Difference ◽  
Sodium Phosphate Solution ◽  
The Uk

BackgroundCorticosteroids are used to treat conditions including acute asthma and croup where they are often given in short-courses. This study evaluated the tolerability and palatability of oral prednisolone and dexamethasone in children in Saudi Arabia (SA) and the UK.MethodsA prospective observational/interview study was performed. Palatability was evaluated by asking patient/parent’s opinions of the taste and acceptability of the medication. Children pointed at the appropriate face on a scale depicting: 1 ‘dislike very much’, 2 ‘dislike a little’, 3 ‘not sure’, 4 ‘like a little’ and 5 ‘like very much’.1 Tolerability, in particular nausea, vomiting and abdominal pain was evaluated by direct questioning of the patient/parents after each administration. Data was collected over three months in each centre. Patients aged 2–18 years treated with oral prednisolone or dexamethasone in hospital were approached to participate.ResultsIn SA, 122 patients (89 asthma, 33 croup), aged 2–10 years (mean=4.3) were recruited: 52 received prednisolone base tablets; 37 prednisolone sodium phosphate syrup; 33 dexamethasone elixir. In the UK, of 133 patients (80 asthma, 53 croup) aged 2–16 years (mean=4.9): 38 received prednisolone base tablets; 42 prednisolone sodium phosphate soluble tablets; 53 dexamethasone sodium phosphate oral solution.SA: Day 1 prednisolone base tablet palatability scores: 1 (88.5%); 2 (11.5%). Day 2 scores: 1 (64.4%); 2 (28.9%); 3 (6.7%). Day 1 prednisolone sodium phosphate solution palatability scores: 1 (48.6%); 2 (40.5%); 3 (10.8%). Day 2 scores: 1 (10.8%); 2 (67.6%); 3 (21.6%). Day 1 dexamethasone elixir palatability scores: 1 (27.3%); 2 (48.5%); 3 (24.2%).UK: Day 1 prednisolone base tablet palatability scores: 1 (76.3%); 2 (13.1%); 3 (5.3%); 4 (5.3%). Day 2 scores: 1 (61.3%); 2 (19.4%); 3 (16.1%); 4 (3.2%). Day 1 prednisolone sodium phosphate soluble tablet palatability scores: 1 (35.7%); 2 (26.2%); 3 (23.8%); 4 (11.9%) 5 (2.4%). Day 2 scores: 1 (16.7%); 2 (58.2%); 3 (16.7%); 4 (4.2%); 5 (4.2%). Day 1 dexamethasone sodium phosphate solution palatability scores: 1 (5.7%); 2 (28.3%); 3 (37.7%); 4 (17%); 5 (11.3%).Dexamethasone sodium phosphate solution had the highest palatability scores (P<706;0.0001). The score was lowest for prednisolone base tablets in both centres (P<0.0001).In SA prednisolone base tablets were associated with more cases of nausea (24 vs 7) and vomiting (5 vs 0) than prednisolone sodium phosphate syrup (p=0.008 and p=0.073 respectively). In the UK vomiting occurred significantly more frequently with prednisolone base tablets (8) than prednisolone sodium phosphate soluble tablets (2) (p=0.041).In both centres dexamethasone was associated with less side effects but with no significant difference between the formulations. Vomiting (1 vs 0), nausea (7 vs 3) and abdominal pain (10 vs 8) occurred more with dexamethasone sodium phosphate solution than dexamethasone elixir (p=1, p=0.53 and p=0.55 respectively).ConclusionsDexamethasone sodium phosphate solution was the most palatable preparation. Prednisolone base tablets were rated the least palatable and were also the least well tolerated. Palatability scores seemed to improve with second doses.ReferenceH. Hames H, Seabrook JA, Matsui D, Rieder MJ, Joubert GI. A palatability study of a flavoured dexamethasone preparation versus prednisolone liquid in children. Can. J. Clin. PharmacolJanuary 2008;15(1):e95–8.

Mechanism of Flue Gas Desulfurization with Sodium Phosphate Solution

2014 ◽  
Vol 37 (12) ◽  
pp. 2185-2189 ◽  
Author(s):  
Zhiguo Yuan ◽  
Wei Song ◽  
Youzhi Liu ◽  
Xiaofeng Kang ◽  
Bo Peng
Keyword(s):  
Flue Gas ◽  
Sodium Phosphate ◽  
Flue Gas Desulfurization ◽  
Phosphate Solution ◽  
Sodium Phosphate Solution

scholarly journals Effects of a new intravenous electrolyte solution for veterinary therapy on the electrolyte and acid-base balances of healthy horses

2016 ◽  
Vol 46 (8) ◽  
pp. 1479-1485 ◽  
Author(s):  
Priscilla Fajardo Valente Pereira ◽  
José Antonio Bessegatto ◽  
Gabriela de Castro Bregadioli ◽  
Stéfany Lia Oliveira Camilo ◽  
Nathali Adrielli Agassi de Sales ◽  
...  
Keyword(s):  
Electrolyte Solution ◽  
Fluid Therapy ◽  
Repeated Measures ◽  
Venous Blood ◽  
Isotonic Saline ◽  
Acid Base Balance ◽  
Acid Base ◽  
Before And After ◽  
Base Balance ◽  
Clinical Changes

ABSTRACT: The effects of a new intravenous electrolyte solution for veterinary therapy on electrolyte and acid-base balances of horses were evaluated, assessing the potential of the use of this solution as a rational alternative in fluid therapy. Eight healthy adult horses, including 4 males and 4 females, received two treatments in a cross-over design: isotonic saline solution (IS) and a test solution (TS) containing 145mEq of Na+, 5mEq of K+, 4mEq of Ca++, 2mEq of Mg++, 96mEq of Cl-, 60mEq of lactate, 50g of dextrose, and 4mg of cyanocobalamin per liter. Solutions were IV infused in a volume corresponding to 5% of BW, over 3 hours. Venous blood samples were taken 5 times before and after the infusion (at 0, 3, 6, 9 e 24h), for pHv, pCO2v, HCO3 -v, BEv, Na+, K+, Cl-, Ca++, Ca, P, Mg, glucose and L-lactate measurements, and AG and SID calculations. The data were analyzed through repeated measures ANOVA. The IS caused mild acidifying effect by increasing Cl- and decreasing plasma SID. In contrast, the TS induced mild and transient hypochloremia without changes in acid-base balance. Hyperglycemia was present at the end of the TS infusion and reversed 6 hours later. The horses did not exhibit any clinical changes. We concluded that TS is an option for fluid therapy in horses.

Synthesis and Characterization of Ag Doped Hydroxylapatite via the Decomposition of EDTA Chelate

2010 ◽  
Vol 297-301 ◽  
pp. 25-29
Author(s):  
Dilara Cayir ◽  
Celaletdin Ergun ◽  
Sabahattin Guvendik
Keyword(s):  
Silver Nitrate ◽  
Sodium Phosphate ◽  
Precipitation Method ◽  
Synthesis And Characterization ◽  
Phosphate Solution ◽  
Antibacterial Effects ◽  
Sodium Phosphate Solution ◽  
In Situ Coating

It has been proven that HA coatings on implant materials treated with silver exhibited excellent antibacterial effects. Silver (Ag) ions were successfully incorporated into HA structure with the precipitation method. Although this method was pretty much suitable for the synthesis in powder form, it is not applicable to in-situ coating processes. The aim of the current study is to synthesize Ag ion incorporating HA via the decomposition of EDTA Chelate. For this reason, Ag doped crystalline-sodium and carbonate-containing HA solutions will be prepared using calcium-EDTA in a sodium phosphate solution, hydrogen peroxide and silver nitrate. As the source of Ag ions, silver nitrate was added into the solution in the desired proportions. Then, the samples were sintered at temperatures from 800oC to 1100oC and characterized with XRD and SEM.

scholarly journals Effect of Saturation and Post Processing on 3D Printed Calcium Phosphate Scaffolds

2008 ◽  
Vol 396-398 ◽  
pp. 663-666 ◽  
Author(s):  
Tamas D. Szucs ◽  
Dermot Brabazon
Keyword(s):  
Mechanical Properties ◽  
Calcium Phosphate ◽  
Sodium Phosphate ◽  
Three Dimensional ◽  
Surface Topology ◽  
Phosphate Solution ◽  
X Ray Diffraction ◽  
Three Dimensional Printing ◽  
Sodium Phosphate Solution ◽  
3D Printed

Three dimensional printing was investigated for fabricating hydroxyapatite (HA) and β-tricalcium phosphate (β-TCP) composite scaffolds using calcium phosphate based ceramics and calcium phosphate cement chemistry. Scaffolds were formed by printing an aqueous sodium phosphate solution on the powder bed consisting of a mixture of dicalcium phosphate anhydrous (DCPA) and calcium hydroxide powders. The sodium phosphate solution was functioning as a binder material and also as the initiator of the wet chemical reaction. Compressive mechanical properties of printed samples were examined as a function of saturation level that was inversely proportional to the powder to liquid ratio. To increase mechanical properties and obtain hydroxyapatite and β-TCP composites, the printed samples were sintered. The effect of sintering parameters including dwell time and sintering temperature were also examined. X-ray diffraction (XRD) was used to examine material composition at different stages of the manufacturing process and to confirm the presence of HA and β-TCP in the final stage. The effect of sintering procedure on the surface topology of the samples was examined using scanning electron microscopy (SEM).

Sign in / Sign up

Export Citation Format

Share Document