scholarly journals Alcohol, drugs and much more in later life

2002 ◽  
Vol 24 (suppl 1) ◽  
pp. 34-41 ◽  
Author(s):  
Gary K Hulse
Keyword(s):  
Drug Use ◽  
Drug Users ◽  
Management Practice ◽  
Later Life ◽  
Attention And Memory ◽  
Medical Practitioners ◽  
Social Events ◽  
Age Related ◽  
Drug Concentrations ◽  
Problem Alcohol

Elderly adults are greater consumers of prescription and 'over the counter' medications than any other age group and polypharmacy, including the co-use of alcohol, is common in this group. Age related physiological changes which influence drug concentrations, metabolism, polypharmacy and interaction of other drugs with alcohol can negatively influence functional capacity, psychomotor ability, and cognition, including attention and memory, placing the older person at greater risk of accident, injury, isolation and ultimately institutionalisation. It is argued that DSM-IV criteria used to define "abuse" or "dependence" are of limited value to the majority of elderly 'problem' alcohol or drug users, with ICD-10 criteria that identify those who are experiencing 'a risk' of or where use "is actually" causing "early" harm, more appropriate. Impediments to psychiatrists and other medical practitioners identifying 'problem' alcohol and other drug use, and appropriate assessment and intervention procedures are briefly discussed. The potential for decreasing the incidence and severity of physical and psycho/social events following a reduction or cessation in problem alcohol or other drug use means that assessment and intervention should be one cornerstone of management practice for this often disenfranchised and vulnerable group.

Differences in Background and Drug Use History among Three Types of Drug Users Entering Drug Therapy Programs

1977 ◽  
Vol 7 (4) ◽  
pp. 369-379 ◽  
Author(s):  
Bill Curtis ◽  
D. Dwayne Simpson
Keyword(s):  
Drug Therapy ◽  
Discriminant Analysis ◽  
Drug Use ◽  
Drug Users ◽  
Multiple Discriminant Analysis ◽  
Age Related ◽  
Drug History ◽  
Use Categories

The 26,316 patients who entered drug therapy programs participating in the DARP from June, 1971, to March, 1973, and who had used drugs for at least two years were grouped into three drug use categories: daily users of opioids, less-than-daily users of opioids, and non-users of opioids. Differences were observed among these three groups regarding the first drug used daily and the age at first drug use. A multiple discriminant analysis including demographic, drug history, and personal background variables indicated that the major differences among these types of drug users revolved around ethnic and age-related variables.

Recreational Prescription Drug Use Among College Students

NASPA Journal ◽  
2006 ◽  
Vol 43 (1) ◽  
Author(s):  
Ethan A Kolek
Keyword(s):  
Drug Use ◽  
Prescription Drug ◽  
Undergraduate Students ◽  
Prescription Drugs ◽  
Drug Users ◽  
Research University ◽  
Future Research ◽  
Negative Consequences ◽  
Prescription Drug Use ◽  
Other Substances

The purpose of this study was to explore recreational prescription drug use among undergraduate students. Although anecdotal accounts on this subject abound, empirical research is extremely limited. Data from a survey of a random sample of 734 students at a large public research university in the Northeast were examined. Results indicate that a substantial proportion of students reported having used prescription drugs for recreational purposes in the year prior to survey administration. Recreational prescription drug use was positively associated with the use of other substances including alcohol. Recreational prescription drug users were also more likely than other drug users to report negative consequences as a result of their drug use. Implications for future research and for student affairs are discussed.

scholarly journals A Biomarker-based Biological Age in UK Biobank: Composition and Prediction of Mortality and Hospital Admissions

2021 ◽  
Author(s):  
Mei Sum Chan ◽  
Matthew Arnold ◽  
Alison Offer ◽  
Imen Hammami ◽  
Marion Mafham ◽  
...  
Keyword(s):  
Principal Components ◽  
Hospital Admissions ◽  
Later Life ◽  
Chronological Age ◽  
Uk Biobank ◽  
Hand Grip ◽  
Cox Proportional Hazard ◽  
Prediction Of Mortality ◽  
Age Related ◽  
Cox Proportional Hazard Models

Abstract Background Chronological age is the strongest risk factor for most chronic diseases. Developing a biomarker-based age and understanding its most important contributing biomarkers may shed light on the effects of age on later-life health and inform opportunities for disease prevention. Methods A subpopulation of 141 254 individuals healthy at baseline were studied, from among 480 019 UK Biobank participants aged 40–70 recruited in 2006–2010, and followed up for 6–12 years via linked death and secondary care records. Principal components of 72 biomarkers measured at baseline were characterized and used to construct sex-specific composite biomarker ages using the Klemera Doubal method, which derived a weighted sum of biomarker principal components based on their linear associations with chronological age. Biomarker importance in the biomarker ages was assessed by the proportion of the variation in the biomarker ages that each explained. The proportions of the overall biomarker and chronological age effects on mortality and age-related hospital admissions explained by the biomarker ages were compared using likelihoods in Cox proportional hazard models. Results Reduced lung function, kidney function, reaction time, insulin-like growth factor 1, hand grip strength, and higher blood pressure were key contributors to the derived biomarker age in both men and women. The biomarker ages accounted for >65% and >84% of the apparent effect of age on mortality and hospital admissions for the healthy and whole populations, respectively, and significantly improved prediction of mortality (p < .001) and hospital admissions (p < 1 × 10−10) over chronological age alone. Conclusions This study suggests that a broader, multisystem approach to research and prevention of diseases of aging warrants consideration.

scholarly journals Sexuality in Later Life and Mental Health Among Older Black Gay Men

2020 ◽  
Vol 4 (Supplement_1) ◽  
pp. 313-314
Author(s):  
Darlingtina Esiaka ◽  
Alice Cheng ◽  
Candidus Nwakasi
Keyword(s):  
Mental Health ◽  
Gay Men ◽  
Later Life ◽  
The United States ◽  
Mental Wellbeing ◽  
Self Identity ◽  
Sexual Identities ◽  
Age Related ◽  
Wide Range ◽  
Black Gay Men

Abstract Self-acknowledgement and integration of racial and sexual identities are significant to one’s overall sense of identity because of their implications for mental health and wellbeing. These issues are important as one ages because older people experience a wide range of factors that add layers to their ability to (re)integrate subsets of their identity into their overall self-identity such as age and age-related disabilities. This study examined the intersection of race and sexual identities on overall health status in older Black gay men, a demographic group that has historically received less attention. Data from the Social Justice Sexuality (SJS) survey of LGBTQ+ people of color which occurred over a 12-month period in the United States were analyzed. Participants (N=160), 50 years and over, responded to questions about their sexuality, social identity, family dynamics, community connection and engagement, and mental and physical health. Results show an association of mental wellbeing with racial and sexual identities. Further, results show that a strong sense of connection to other sexual minorities is positively associated with mental health in older Black gay men. We discuss the implication of findings for mental health interventions targeting this gendered population.

scholarly journals Physical Resilience as a Determinant of Healthspan and Lifespan in Mice

2020 ◽  
Vol 4 (Supplement_1) ◽  
pp. 829-829
Author(s):  
Nathan LeBrasseur
Keyword(s):  
Middle Ages ◽  
Interest Group ◽  
Later Life ◽  
Cytotoxic Drugs ◽  
Geriatric Syndromes ◽  
Age Related ◽  
Fundamental Biology ◽  
Dynamic Measures ◽  
Biology Of Aging ◽  
Insight Into

Abstract Dynamic measures of physical resilience—the ability to resist and recover from a challenge—may be informative of biological age far prior to overt manifestations such as age-related diseases and geriatric syndromes (i.e., frailty). If true, physical resilience at younger or middle ages may be predictive of future healthspan and lifespan, and provide a unique paradigm in which interventions targeting the fundamental biology of aging can be tested. This seminar will discuss research on the development of clinically-relevant measures of physical resilience in mice, including anesthesia, surgery, and cytotoxic drugs. It will further highlight how these measures compare between young, middle-aged, and older mice, and how mid-life resilience relates to later-life healthspan. Finally, it will provide insight into whether interventions targeting the biology of aging can modify physical resilience in mice. Part of a symposium sponsored by Epidemiology of Aging Interest Group.

scholarly journals Illicit Drug Use in Canada and Implications for Suicidal Behaviors, and Household Food Insecurity: Findings from a Large, Nationally Representative Survey

2021 ◽  
Vol 18 (12) ◽  
pp. 6425
Author(s):  
Nicola Luigi Bragazzi ◽  
Dan Beamish ◽  
Jude Dzevela Kong ◽  
Jianhong Wu
Keyword(s):  
Suicidal Ideation ◽  
Drug Use ◽  
Food Insecurity ◽  
Drug Users ◽  
Illicit Drug ◽  
Illicit Drug Use ◽  
Household Food Insecurity ◽  
Household Food ◽  
Suicidal Attempts ◽  
Nationally Representative

Background and Aims: Illicit drug use is an ongoing health and social issue in Canada. This study aimed to investigate the prevalence of illicit drug use and its implications for suicidal behaviors, and household food insecurity in Canada. Design: Cross-sectional population survey. Setting: Canada, using the 2015–2016 Canadian Community Health Survey, a nationally representative sample selected by stratified multi-stage probability sampling. Participants: A total of 106,850 respondents aged ≥ 12 years who had completed information on illicit drug use. Measurements: Illicit drug use was assessed through a series of questions about illicit drug use methods. Respondents who reported lifetime illicit drug use but no past-year use were considered to have prior illicit drug use. In this survey, illicit drug use included cannabis use. Findings: Overall, the prevalence of lifetime, past-year, and prior illicit drug use was 33.2% (9.8 million), 10.4% (3.1 million), and 22.7% (6.7 million), respectively. In models adjusting for sociodemographic covariates, prior illicit drug use was significantly associated with increased odds of past-year suicidal ideation (adjusted odds ratio [AOR] 1.21, 95% CI 1.04–1.40), and plans (1.48, 1.15–1.91), and past-year household food insecurity (1.27, 1.14–1.41), and the odds were much higher among prior injecting drug users than prior non-injecting drug users. No significant correlation was found between prior illicit drug use and past-year suicidal attempts, but there was a strong association between past-year illicit drug use and past-year suicidal attempts. Conclusions: Our findings suggest that even after people have stopped taking illicit drugs, prior illicit drug use, especially for prior injecting drug use, continues to be associated with increased risks of subsequent suicidal ideation, and plans, and household food insecurity.

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