Microscopic analysis of dog dental pulp after pulpotomy and pulp protection with mineral trioxide aggregate and white Portland cement

Considering previous studies on the similarity between the chemical composition of the mineral trioxide aggregate and the Portland cement, the purpose of this study was to investigate the pulp response of dog's teeth after pulpotomy and direct pulp protection with MTA Angelus and white Portland cement. Thirty eight pulp remnants were protected with these materials. One hundred and twenty days after treatment, the animals were sacrificed and the specimens removed and prepared for histological analysis. Both materials demonstrated the same results when used as pulp capping materials, inducing hard tissue bridge formation and maintaining pulp vitality in all specimens. The MTA Angelus and the white Portland cement showed to be effective as pulp protection materials following pulpotomy.

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Comparison of Chemical Composition between Indonesian White Portland Cement and MTA as Dental Pulp Capping Material

Key Engineering Materials ◽

10.4028/www.scientific.net/kem.829.34 ◽

2019 ◽

Vol 829 ◽

pp. 34-39

Author(s):

Denny Nurdin ◽

Indra Primathena ◽

Rahmi Alma Farah ◽

Arief Cahyanto

Keyword(s):

Chemical Composition ◽

Portland Cement ◽

Dental Pulp ◽

Functional Group ◽

Mineral Trioxide Aggregate ◽

Pulp Capping ◽

Dental Pulp Capping ◽

Pulp Exposure ◽

And Control ◽

White Portland Cement

Pulp capping has been suggested as one treatment of choice after pulp exposure. Calcium hydroxide [Ca (OH)2] recognized as gold standard of direct pulp capping matter for some decades. Throughout the time, a new cement known as mineral trioxide aggregate (MTA) has developed into a prominent alternative. A recent study found that matter as the most effective pulp capping material. Despite the fact, MTA is an expensive material. Several studies in different country show that portland cement has highly similarity chemical composition with MTA. The purpose of this study is to evaluate the chemical composition of white portland cement that fabricated in Indonesia compared to MTA. White portland cement fabricated in Indonesia was used as a sample in this study and commercial MTA as a control. Samples and control were assessed using X-ray fluorescence spectrometry (XRF) to figure out chemical composition and concentration. Investigating the wavelength of the functional group using Fourier Transform Infrared Spectroscopy (FTIR). The results show that composition, concentration, and functional group either Indonesian white portland cement and MTA has highly similar. Hence, it has a chance to use Indonesian white portland cement for dental pulp capping material as MTA substitution.

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Immediate response of human dental pulp capped with mineral trioxide aggregate, Portland cement and biodentin

Bangladesh Medical Research Council Bulletin ◽

10.3329/bmrcb.v45i2.42540 ◽

2019 ◽

Vol 45 (2) ◽

pp. 108-116

Author(s):

AKM Bashar ◽

A.K.M Nurul Kabir ◽

Rozina Akhter Rizdina ◽

Ranjit Ghosh ◽

Ashis Kumar Biswas ◽

...

Keyword(s):

Portland Cement ◽

Inflammatory Reaction ◽

Dental Pulp ◽

Mineral Trioxide Aggregate ◽

Tissue Reaction ◽

Control Group ◽

Pulp Capping ◽

Pulp Inflammation ◽

Significant Difference ◽

Human Dental Pulp

Background: The initial inflammatory reaction of pulp capping materials on the dental pulp has an intimate relation in promoting the future cellular differentiation and biomaterial mineralisation. So, analysis of immediate pulpal tissue reaction in vivo, is also important for evaluation of ultimate efficacy any pulp capping agent. To observe immediate inflammatory response of Human Dental Pulp capped with Mineral Trioxide Aggregate (MTA), Biodentin and Portland Cement (PC). Methods: A total of 70 permanent premolars teeth planned to be extracted for orthodontic alignment of occlusion were used as study sample. The teeth were divided into 3 experimental groups, MTA (n=20), Biodentin (n=20) Portland cement (n=20) and control group (n=10). After having an occlusal exposure of approximately 1.5 mm in diameter; in group A, pulp of teeth was capped with 2-mm-thick layer of ProRoot White MTA (Dentsply) and in group B, with sterile Biodentin (Septodont) according to the manufacturer’s recommendations. Whereas in group C, pulp of teeth was capped with sterile Portland Cement (PC). After placing the experimental material in each group, all teeth restored with glass i‹xiomer cement. After 24 hours the teeth were extracted, fixed in 10% buffered formalin solution, then decalcified by 10% nitric acid and embedded in paraffin. Finally, sectioned into 2 to 3-micron-thick serial sections in the linguo-buccal plane and stained with hematoxylin-eosin. After then the amount of pulp inflammation (type, intensity, and extension) were determined by using a predetermined evaluation criterion under an optical microscope at 40a magnification. Ten intact teeth, which received no exposure and pulp capping but extracted due to orthodontic purpose were also collected and treated as the control group (group D); undergone same histologic preparation and evaluation. Significantstatistical differences among the experimental groups were to be found (p<0.05). Results: Histologically, all the three tested materials produced immediate pulpal tissue reaction. ‘Biodentin’ found to be most immediate pulpal tissue reactive (reactive in 100% cases) and ‘Portland Cement’ showed least immediate tissue reaction (only in 30.0% cases). whereas, MTA produced immediate tissue reaction only in 50.0% cases. Immediate pulpal inflammatory reaction in response to tested material found to be statistically significant different between ‘Biodentin’ and ‘Portland cmient’ (p=0.01), also between ‘Biodentin’ and ‘MTA’ and (p=0.001); but there was no statistically significant difference between ‘MTA’ and ‘Portland cement’ (p =0.197). Conclusion: Considering the maximum immediate pulpal tissue reaction (Inflammation), Biodentin is expected to produce most favorable ultimate bioactivity (biomaterial mineralization) after pulp capping. Bangladesh Med Res Counc Bull 2019; 45: 108-116

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COMPARATIVE ANALYSIS OF CLINICAL EFFICIENCY OF THE DRUG “BIO-DENT” IN BIOLOGICAL METHODS OF TREATMENT OF PULPITES BY THE METHOD OF INDIRECT COATING

UZBEK MEDICAL JOURNAL ◽

10.26739/2181-0664-2021-si-1-9 ◽

2021 ◽

Vol Special issue (1) ◽

pp. 51-56

Author(s):

Nigora Djuraeva ◽

Keyword(s):

Comparative Analysis ◽

Portland Cement ◽

Calcium Hydroxide ◽

Dental Pulp ◽

Mineral Trioxide Aggregate ◽

Clinical Efficiency ◽

Near Term ◽

Biological Methods ◽

Methods Of Treatment

The article presents the results of using a material based on the mineral trioxide unit “Bio-Dent”for the indirect coating of the pulp. It was found that there were no complaints from the use of domestic Portland cement both in the near term (98.8%) and inthe long term after treatment in comparison with materials based on calcium hydroxide (72.5%). Stabilization of the pulp electroexcitability indicators at the level of 10 mkA was noted with the use of the material based on MTA “Bio-Dent”as a medical liner for indirect pulp covering.Keywords: dental pulp,indirect pulp coating, calcium hydroxide, mineral trioxide aggregate, pulp electroexcitability.

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Decision-Making and Management of Immature Permanent Teeth with Crown Fractures in Small Animals—A Review

Journal of Veterinary Dentistry ◽

10.1177/08987564211046325 ◽

2021 ◽

pp. 089875642110463

Author(s):

Amalia Zacher ◽

Sandra Manfra Marretta

Keyword(s):

Treatment Options ◽

Mineral Trioxide Aggregate ◽

Permanent Teeth ◽

Small Animals ◽

Unique Challenge ◽

Pulp Capping ◽

Pulp Therapy ◽

Vital Pulp Therapy ◽

Pulp Vitality ◽

And Function

Immature permanent teeth with crown fractures present a unique challenge in human and animal patients. Immature permanent teeth have not yet developed completely, often presenting with thin dentin walls, incomplete apical formation, and increased crown-to-root ratios. Loss of pulp function at this stage has devastating long-term implications for these teeth. Ideally, attempts should be made to preserve pulp vitality in immature permanent teeth to allow for continued dental development. The range of treatment options for vital teeth includes odontoplasty with bonding and sealing +/− restoration, indirect pulp capping, and direct pulp capping/vital pulp therapy. These treatments have long been established in human and veterinary medicine, and cases have been reported in dogs and cats. Apexification using calcium hydroxide is a well-established treatment for nonvital immature teeth. The advent of mineral trioxide aggregate and other bioceramic materials for use in vital pulp therapy and apexification has reduced treatment sessions and improved outcomes. Recent developments in the field of regenerative endodontic therapy further expand treatment options and provide the possibility for continued development of a formerly nonvital tooth. Selecting the appropriate treatment based on the severity of tooth fracture and status of pulp vitality can avoid a lifetime of poor structure and function for the affected tooth. This article provides multiple step-by-step protocols for the management of immature permanent teeth with crown fractures in small animals.

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Analysis of hard tissue regeneration and Wnt signalling in dental pulp tissues after direct pulp capping with different materials

International Endodontic Journal ◽

10.1111/iej.13162 ◽

2019 ◽

Vol 52 (11) ◽

pp. 1605-1616 ◽

Cited By ~ 5

Author(s):

K. Yaemkleebbua ◽

T. Osathanon ◽

N. Nowwarote ◽

C. N. Limjeerajarus ◽

W. Sukarawan

Keyword(s):

Tissue Regeneration ◽

Dental Pulp ◽

Wnt Signalling ◽

Direct Pulp Capping ◽

Hard Tissue ◽

Pulp Capping

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Evaluation of clinical and radiological outcomes of mineral trioxide aggregate and calcium hydroxide as indirect pulp capping agents in the treatment of deep carious lesion of permanent teeth

Bangabandhu Sheikh Mujib Medical University Journal ◽

10.3329/bsmmuj.v9i3.29462 ◽

2016 ◽

Vol 9 (3) ◽

pp. 140 ◽

Cited By ~ 2

Author(s):

Rafeza Sultana ◽

Mozammal Hossain ◽

Md. Shamsul Alam

Keyword(s):

Calcium Hydroxide ◽

Mineral Trioxide Aggregate ◽

Permanent Teeth ◽

Capping Agents ◽

Pulp Capping ◽

Carious Lesions ◽

Reparative Dentin ◽

Deep Carious Lesions ◽

Pulp Vitality ◽

Indirect Pulp Capping

<p>The maintenance of pulp vitality and conduction of reparative dentin can be possible by indirect pulp capping with mineral trioxide aggregate (MTA) and calcium hydroxide as pulp capping agents. The objective of the study is to assess the clinical and radiological outcomes of MTA and calcium hydroxide as indirect pulp capping agents in deep carious lesions of permanent teeth. The present study included 50 permanent teeth having deep carious lesions with reversible pulp status were selected and then randomly divided into two groups of 25 teeth in a group. Standard indirect pulp capping procedures were followed. Patients were recalled at 3, 6 and 12 months interval to assess postoperative pain, the vitality of the pulp and formation of reparative dentin. In all observation periods, MTA showed more capable of reducing pain and maintain pulp vitality which was statistically significant than that of calcium hydroxide. At 12 months observation period, 24 teeth (96%) of MTA and 19 teeth (76%) of calcium hydroxide showed reparative dentin formation. It can be concluded that MTA is more effective than that of calcium hydroxide.</p><p> </p>

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Histomorphological response of dogs' dental pulp capped with white mineral trioxide aggregate

Brazilian Dental Journal ◽

10.1590/s0103-64402004000200004 ◽

2004 ◽

Vol 15 (2) ◽

pp. 104-108 ◽

Cited By ~ 23

Author(s):

Italo Medeiros Faraco Junior ◽

Roberto Holland

Keyword(s):

Dental Pulp ◽

Healing Process ◽

Mineral Trioxide Aggregate ◽

Morphological Aspect ◽

Bridge Formation ◽

Pulp Capping ◽

Exposure Site ◽

Pulp Inflammation ◽

White Mineral

This study was conducted to observe the response of dogs' dental pulp to white mineral trioxide aggregate (MTA) when used as pulp capping material. The pulp of 15 dogs' teeth was experimentally exposed and capped with white MTA. The animals were sacrificed two months later and the specimens were prepared for histomorphological study. The pulp capped with white MTA showed a healing process with complete dentin bridge formation in all samples. In some cases, there was not a tubular dentin shape, but only a structure with an interesting morphological aspect sealing the exposure site. Only 2 specimens exhibited pulp inflammation. In conclusion, the data obtained in this study showed that white MTA has the necessary properties of a pulp capping material.

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