Adverse Effects of COVID-19 Treatments: A Special Focus on Susceptible Populations

Author(s):  
BEYZA NUR KÜÇÜK ◽  
RAHİME ŞİMŞEK ◽  
SELİNAY BAŞAK ERDEMLİ KÖSE ◽  
ANIL YİRÜN ◽  
Pinar Erkekoglu
2020 ◽  
Vol 15 (4) ◽  
pp. 379-387
Author(s):  
Aryendu K. Saini ◽  
Rakesh Saini ◽  
Himanshu Bansode ◽  
Anurag Singh ◽  
Lalita Singh

Stem cells are the undifferentiated cells in the body that possess the ability to differentiate and give rise to any type of cells in the body. In recent years, there has been a growing interest in therapies involving stem cells as different treatment methods got developed. Depending on the source, there are two major kinds of stem cells, embryonic and adult stem cells. The former type is found in the embryo at the different developmental stages before the implantation and excels the latter owing to pluripotency. On the premise of the attributes of stem cells, they are touted as the "panacea for all ills" and are extensively sought for their potential therapeutic roles. There are a lot of robust pieces of evidence that have proved to cure the different ailments in the body like Huntington disease, Parkinson's disease, and Spinal cord injury with stem cell therapy but associated with adverse effects like immune rejection and teratoma formation. In this regard, the pre-morula (isolated at an early pre-morula stage) stem cells (PMSCs) are one of its kind of embryonic stem cells that are devoid of the aforementioned adverse effects. Taking the beneficial factor into account, they are being used for the treatment of disorders like Cerebral palsy, Parkinson's disorder, Aplastic anemia, Multiple sclerosis and many more. However, it is still illegal to use stem cells in the abovementioned disorders. This review encompasses different stem cells and emphasizes on PMSCs for their uniqueness in therapy as no other previously published literature reviews have taken these into consideration. Later in the review, current regulatory aspects related to stem cells are also considered.


2011 ◽  
Vol 26 (S1) ◽  
pp. s133-s134
Author(s):  
D. Doshi

Paediatric asthma is a frequent presentation to Emergency departments. Early intervention may prevent progression of the acute phase to a severe or life threatening stage. Magnesium is a wonder molecule that has repeatedly undergone vigorous trials. Magnesium is used by intravenous and nebulized route in many guidelines across the world. Heliox keeps coming in and falling out of favour with conflicting literature reviews. Its simplicity of use makes it an effective tool in the treatment of exacerbations of asthma. Aminophylline is one of the earliest bronchodilator that has heaps of adverse effects. This presentations begins with a world tour of major guidelines with a special focus on Magnesium, Aminophylline and Heliox followed by an in depth literature search. Current literature and metanalysis for all the three drugs for pulmonary function test, hospitalisation and adverse effects are graphically illustrated. Based on the evidence so far, a guideline is proposed for the use of the above three drugs for Paediatric asthma.


2016 ◽  
Vol 7 (3) ◽  
pp. 514-525 ◽  
Author(s):  
Ahmed M. Alabdulkader ◽  
Ahmed I. Al-Amoud ◽  
Fawzi S. Awad

This research paper highlights the adverse effects of climate change on the agricultural sector in Saudi Arabia and the actions taken to adapt to these adverse effects. Special focus was given to the potential to optimise the reallocation of scarce water resources among the competitive advantage date palm cropping regions in Saudi Arabia using a mathematical sector modelling approach. The results showed great potential for Saudi Arabia to adapt to the adverse effects of climate change by optimising the date palm cropping pattern in accordance with its scarce water resources and limited cultivated lands. The optimised scenario would result in a high net annual return, equivalent to about 881.76 million US$ year−1, and an increase on the water use return from about 0.97 US$ cm−1 in the base year to approximately 1.31 US$ cm−1. The optimised scenario would also provide the opportunity to reduce the allocated date palm cropping area by approximately 4% (from approximately 118,250 hectares to approximately 113,446 hectares) and to reduce the water demand by approximately 1% (from 681.06 million cubic metres (MCM) per year to approximately 674.28 MCM per year).


2012 ◽  
Vol 12 (1) ◽  
pp. 103-109 ◽  
Author(s):  
Shamsa Ali ◽  
Vivian Fonseca

Author(s):  
Nestor J. Zaluzec

The application of electron energy loss spectroscopy (EELS) to light element analysis is rapidly becoming an important aspect of the microcharacterization of solids in materials science, however relatively stringent requirements exist on the specimen thickness under which one can obtain EELS data due to the adverse effects of multiple inelastic scattering.1,2 This study was initiated to determine the limitations on quantitative analysis of EELS data due to specimen thickness.


VASA ◽  
2012 ◽  
Vol 41 (5) ◽  
pp. 313-318 ◽  
Author(s):  
Ernemann ◽  
Bender ◽  
Melms ◽  
Brechtel ◽  
Kobba ◽  
...  

Interventional therapies using angioplasty and stenting of symptomatic stenosis of the proximal supraaortic vessels have evolved as safe and effective treatment strategies. The aim of this paper is to summarize the current treatment concepts for stenosis in the subclavian and brachiocephalic artery with regard to clinical indication, interventional technique including selection of the appropriate vascular approach and type of stent, angiographic and clinical short-term and long-term results and follow-up. The role of hybrid interventions for tandem stenoses of the carotid bifurcation and brachiocephalic artery is analysed. A systematic review of data for angioplasty and stenting of symptomatic extracranial vertebral artery stenosis is discussed with a special focus on restenosis rate.


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