The electrophysiological characteristics of the motor activity of the gastrointestinal tract following selective proximal vagotomy in the patients presenting with ulcerative pyloroduodenal stenosis

2016 ◽  
Vol 5 (3) ◽  
pp. 31 ◽  
Author(s):  
P. M. Kosenko ◽  
S. A. Vavrinchuk ◽  
L. K. Kulikov
1992 ◽  
Vol 263 (4) ◽  
pp. G533-G537
Author(s):  
D. Smith ◽  
B. Waldron ◽  
F. C. Campbell

The characteristics of the phases of the migrating motor complex (MMC) were studied in the antrum, duodenum, and jejunum after alteration of intraluminal gas and acaloric fluid in 17 healthy volunteers. Aspiration of gas and fluid from the upper gastrointestinal tract reduced motor activity. In the antrum and duodenum, phase II contraction amplitude decreased, while in the duodenum and jejunum, the duration of phase II decreased and phase I increased. Phase III contraction frequency decreased in the duodenum only. Intragastric instillation of gas caused an increase of phase II duration and contraction amplitude in all regions. Similar effects were observed after intragastric instillation of fluid. Fasting periodic motor activity is responsive to volume changes of intraluminal gas and acaloric liquid content.


1987 ◽  
Vol 93 (1) ◽  
pp. 114-120 ◽  
Author(s):  
R. Jian ◽  
J. Janssens ◽  
G. Vantrappen ◽  
P. Ceccatelli

1994 ◽  
Vol 72 (2) ◽  
pp. 109-112 ◽  
Author(s):  
E. G. Watson ◽  
J. E. T. Fox-Threlkeld ◽  
E. E. Daniel

Tachykinins induce motor activity in the canine ileum, and their mechanism of excitation may include inhibition of the release of a nonadrenergic, noncholinergic inhibitor, for which vasoactive intestinal polypeptide (VIP) is a candidate. Both substance P and neurokinin A produced a dose-dependent increase in ileal contractility with no significant change in VIP output. The highly selective NK1 agonist [Sar9, Met(O2)11]substance P and the highly selective NK2 agonist [Nle10]neurokinin A (4–10) also increased motor activity in the absence of any change in VIP released. These data suggest that the tachykinins produce motor activity in the canine ileum via a mechanism that does not involve changes in VIP output but may involve excitation through both NK1 and NK2 receptors.Key words: vasoactive intestinal polypeptide, tachykinins, gastrointestinal tract, motility.


1998 ◽  
Vol 274 (3) ◽  
pp. G447-G453 ◽  
Author(s):  
J. H. Szurszewski

This contribution to the centennial commemorative issue of the American Journal of Physiology: Gastrointestinal and Liver Physiology identifies some of the important studies of spontaneous electrical and motor activity in the gastrointestinal tract published in the Journal between 1898 and 1996. Emphasis is given to the contributions made by Walter B. Cannon, Walter C. Alvarez, Emil Bozler, C. Ladd Prosser, and James Christensen.


2003 ◽  
Vol 550 (1) ◽  
pp. 227-240 ◽  
Author(s):  
Kazunori Fujino ◽  
Akio Inui ◽  
Akihiro Asakawa ◽  
Naoki Kihara ◽  
Masaki Fujimura ◽  
...  

2018 ◽  
Vol 42 (4) ◽  
pp. 58-65
Author(s):  
E. Y. Plotnikova ◽  
T. Y. Gracheva ◽  
Y. V. Moskvina

Psychosomatic disorders are frequent in gastroenterological practice. Visceral pain and motor-evacuation disorders of the gastrointestinal tract is a common symptom of functional gastrointestinal disorders which have a multifactorial etiology. Many patients with these diseases have comorbid behavioral disorders, such as anxiety or depression, and functional gastrointestinal disorders are described as disorders of the “gastrointestinal tract-brain” axis. Chronic stress can change the central pattern of pain, as well as motor activity and permeability of the gastrointestinal tract. The multidirectional treatment for these diseases should include psychotropic drugs and groups of somatic antipsychotics and antidepressants.


Author(s):  
A. A. Ziganshina ◽  
V. S. Sukhorukov ◽  
V. P. Bulatov

Purpose.To identify the characteristics of the amino acid profile in children with various disturbances of the motor activity of the gastrointestinal tract. We examined 100 patients treated at the diagnostic department of the Children’s Republican Clinical Hospital of Tatarstan. The main group consisted of 80 patients, 40 of whom were diagnosed with functional constipation, and 40 patients were diagnosed with endoscopically verified gastroesophageal reflux disease. The control group consisted of 20 somatically healthy children with no signs of pathology of the gastrointestinal tract. We determined the content of amino acids in dry blood stains using liquid tandem chromatography-mass spectrometry on Agilent Technologies 6410 Triple Quad LC/MC (USA). We performed statistical analysis of the results using GraphPad InStat (version 3.05; 2000) and Statistica 10.0.Results.We found differences in the amino acid composition of blood of the patients with impaired motor activity of the digestive tract as compared to healthy children. The level of leucine was increased to the greatest extent in the study group. The revealed changes correlated with the severity of the disease.Conclusions. Disorders in the motor activity of the digestive organs are accompanied by changes in the amino acid profile that are associated with the severity of functional constipation and gastroesophageal reflux disease. Some amino acids, in particular leucine and arginine, can be used to diagnose secondary mitochondrial dysfunction in pediatric gastroenterology along with conventional biochemical and chromatomass-spectrometric markers.


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