scholarly journals Exploring the Possibilities of Evaluating the Protective Efficiency of Volatile Inhibitors by Electrochemical Polarization in the Example of Copper and IFHAN-114

Author(s):  
V. I. Vigdorovich ◽  
◽  
L. E. Tsygankova ◽  
L. G. Knyazeva ◽  
N. V. Shel ◽  
...  
1973 ◽  
Vol 71 (4) ◽  
pp. 641-647 ◽  
Author(s):  
D. Hobson ◽  
F. A. Baker ◽  
R. L. Curry ◽  
A. S. Beare ◽  
P. M. O. Massey

Intranasal vaccines of inactivated or living attentuated A2/Hong Kong influenza viruses were compared for clinical acceptability, serological effects and protective efficiency against natural epidemic influenza in a large industrial and clerical population.


1972 ◽  
Vol 21 (6) ◽  
pp. 256-262
Author(s):  
Tadahiko Mizuno ◽  
Tatsushi Suzuki ◽  
Takashi Morozumi

2017 ◽  
Vol 08 (01) ◽  
Author(s):  
Na Young Kim ◽  
Dong Suk Chang ◽  
Gyeung Haeng Hur ◽  
Taek Yeol Lee ◽  
Jai Myung Yang ◽  
...  

2013 ◽  
Vol 28 (1) ◽  
pp. 102-107
Author(s):  
Dusan Rajic ◽  
Negovan Ivankovic ◽  
Natasa Ivankovic ◽  
Marina Ilic ◽  
Zeljko Senic ◽  
...  

The use of ammunition primed with depleted uranium is one of the hallmarks of modern combat operations, resulting in environmental contamination by particles of depleted uranium and uranium oxide, scattered around in the form of submicron-scale aerosols. This paper examined the protective effectiveness of the Serbian military's M3 protective face mask in relation to the presence of airborne depleted uranium and its by-products. Sodium chloride in solid aerosol form was used as a test substance and adequate physical simulator of such radioactive aerosols because its granulometric (particle) size distribution met the requirements of suitability as a simulator. Determination of aerosol concentration was carried out by flame photometry method, whilst granulometric distribution was determined by an electric particles analyzer. It was established that the total internal leakage of the M3 protective mask was as much a function of the penetration of particles through the combined M3 filter as of the leaks along the fitting line of the user's face mask and the inhalation valve. In terms of its protective effect against aerosols of depleted uranium and associated oxides, the Serbian M3 protective mask was determined to be of high efficiency and physiological suitability.


Author(s):  
L. F. Stovba ◽  
V. T. Krotkov ◽  
D. I. Paveli’ev ◽  
S. A. Mel’nikov ◽  
V. N. Lebedev ◽  
...  

The review presents the results of preclinical use of vector vaccines against human immunodeficiency virus (HIV) disease and simian immunodeficiency virus (SIV) disease. Application of antiretroviral therapy exclusively is insufficient for elimination of HIV from patient’s body. This dictates the need for an effective vaccine which will reduce the number of new cases of the disease and reduce the risk of virus transmission. Current practice of medicinal product development showed the effectiveness of heterologous prime-boost regimens for the induction of expressed immune response in laboratory animals. Various vector constructs were used as priming vaccines: DNA vaccines, Bacille Calmette-Guerin vaccine, chimpanzee adenovirus, vesicular stomatitis virus, alphavirus repli-clone. Booster vaccine was represented by recombinant MVA strain. In all vector vaccines, different genes of immunodominant antigens of HIV and SIV agents were inserted. On rhesus macaques, murine, rabbit models, it was demonstrated that deployed vaccination schemes were safe and induced immune response. Because membrane HIV protein is highly variable, strongly glycoziled and subjected to structural changes during receptor binding, it cannot be viewed as a target for induction of virus neutralized antibodies. Therefore, we mainly studied the cell immune response that was presented by poly-functional CD8+ T-cells. However, some recent researches are aimed at such modification of envelope HIV immunogene that would provide for virus neutralizing antibody induction. The study of protective efficiency of the induced immunity in rhesus macaques, immunized with recombinant vectors expressing SIV’ s immunodominant antigens, in case of subsequent inoculation with virulent SIV strain has revealed that all monkeys developed illness. Assuming that the constructions with SIV’ s immunodominant antigens under protective efficiency testing on rhesus macaques imitate AIDS in humans, it seems that vaccines, developed up-to-date, will not be effective for collective immunity formation against AIDS. Therefore, the search for novel combinations of expressed immunodominant antigens for the inclusion into the composition of priming and booster vaccines remains a priority area at present time.


2021 ◽  
Vol 0 (4) ◽  
pp. 20-24
Author(s):  
N.R. Abıshova ◽  
◽  
G.S. Aliyev ◽  
U.M. Gurbanova ◽  
Y.A. Nuriyev ◽  
...  

The essay is about studies of the electrochemical reduction of nickel ions from a glycine electrolyte by the method of recording cyclic and linear potentiodynamic polarization curves. The effect of the concentration of the main components, potential sweep and temperature on the electrodeposition process of nickel has been studied. It has been found that at the beginning of the process the electrodeposition of the nickel ions from glycine electrolyte is controlled by electrochemical polarization, which turns into concentration polarization


Sign in / Sign up

Export Citation Format

Share Document