A Fatal Case of Disseminated Intestinal Mucormycosis in a Patient with Vibrio Sepsis

Mucormycosis is a fungal infection that primarily causes opportunistic infections. Gastrointestinal mucormycosis is a rare infection that can occur in immunocompromised patients, nevertheless, prompt diagnosis and treatment is essential because it can be fatal. Gastrointestinal mucormycosis can only be diagnosed based on the findings of a pathological examination. Mucormycosis should be included in the differential diagnosis if the condition of patients with underlying immunocompromised conditions or diseases does not improve with general intensive care.

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A “Terrible” Headache in a HIV Patient

Ear Nose & Throat Journal ◽

10.1177/01455613211014106 ◽

2021 ◽

pp. 014556132110141

Author(s):

Marios Stavrakas ◽

Ioannis Koskinas ◽

Jannis Constantinidis ◽

Petros D Karkos

Keyword(s):

Differential Diagnosis ◽

Surgical Treatment ◽

Fungal Infection ◽

Early Identification ◽

Fungal Sinusitis ◽

Immunocompromised Patients ◽

Immunosuppressed Patients ◽

Distant Spread ◽

Nose And Throat

Mucormycosis is a type of fungal infection more prevalent among immunosuppressed patients, requires prompt identification and surgical treatment, as it can is associated with local and distant spread. This case is aiming to highlight the importance of early identification of subtle symptoms in immunocompromised patients. The clinician should be aware of fungal sinusitis, consider it in the differential diagnosis, and seek for an ear, nose, and throat opinion.

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Identification and in Vitro Susceptibility Pattern of Fungal Pathogens in Immunocompromised Patients with invasive Fungal Infections

10.51429/ejmm30317 ◽

2021 ◽

Vol 30 (3) ◽

pp. 127-134

Author(s):

Shaimaa A.S. Selem ◽

Neveen A. Hassan ◽

Mohamed Z. Abd El-Rahman ◽

Doaa M. Abd El-Kareem

Keyword(s):

Intensive Care ◽

Fungal Infection ◽

Fungal Pathogens ◽

Fungal Infections ◽

Antifungal Susceptibility ◽

Invasive Fungal Infections ◽

Immunocompromised Patients ◽

University Hospitals ◽

Vitek 2

Background: In intensive care units, invasive fungal infections have become more common, particularly among immunocompromised patients. Early identification and starting the treatment of those patients with antifungal therapy is critical for preventing unnecessary use of toxic antifungal agents. Objective: The aim of this research is to determine which common fungi cause invasive fungal infection in immunocompromised patients, as well as their antifungal susceptibility patterns in vitro, in Assiut University Hospitals. Methodology: This was a hospital based descriptive study conducted on 120 patients with clinical suspicion of having fungal infections admitted at different Intensive Care Units (ICUs) at Assiut University Hospitals. Direct microscopic examination and inoculation on Sabouraud Dextrose Agar (SDA) were performed on the collected specimens. Isolated yeasts were classified using phenotypic methods such as chromogenic media (Brilliance Candida agar), germ tube examination, and the Vitek 2 system for certain isolates, while the identification of mould isolates was primarily based on macroscopic and microscopic characteristics. Moulds were tested in vitro for antifungal susceptibility using the disc diffusion, and yeast were tested using Vitek 2 device cards. Results: In this study, 100 out of 120 (83.3%) of the samples were positive for fungal infection. Candida and Aspergillus species were the most commonly isolated fungal pathogens. The isolates had the highest sensitivity to Amphotericin B (95 %), followed by Micafungin (94 %) in an in vitro sensitivity survey. Conclusion: Invasive fungal infections are a leading cause of morbidity and mortality in immunocompromised patients, with Candida albicans being the most frequently isolated yeast from various clinical specimens; however, the rise in resistance, especially to azoles, is a major concern.

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Isolated rupture of the superficial vein of the penis

Canadian Urological Association Journal ◽

10.5489/cuaj.1712 ◽

2014 ◽

Vol 8 (5-6) ◽

pp. 371

Author(s):

Alper Eken ◽

Meltem Acil ◽

Taner Arpaci

Keyword(s):

Differential Diagnosis ◽

Sexual Intercourse ◽

Male Genitalia ◽

Rare Condition ◽

The Other ◽

Diagnosis And Treatment ◽

Superficial Vein ◽

Dorsal Vein ◽

Prompt Diagnosis ◽

Erect Penis

Penile emergencies are rare but when they do occur, prompt diagnosis and treatment are warranted. Emergent conditions of the male genitalia are mainly traumatic, vascular or infectious. Penile emergencies are usually caused by trauma to the penis, during sexual intercourse or manipulation of an erect penis during masturbation. One of the traumatic vascular penile emergencies is superficial penile dorsal vein rupture. This is a rare condition, with just a few reported cases. It is usually taken into differential diagnosis with the other acute penile injuries that present, such as acute penile edema or ecchymosis. We report a case of 59-year-old male with a superficial penile dorsal vein rupture which occurred during manipulation of the erect penis.

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Osteoid Osteoma: A Unique Presentation in a Child’s Lesser Toe

Case Reports in Orthopedics ◽

10.1155/2021/8876584 ◽

2021 ◽

Vol 2021 ◽

pp. 1-4

Author(s):

Michel Bellemans ◽

Nicolas de Saint-Aubin de Somerhausen ◽

Phu Quoc Lê

Keyword(s):

Young Adults ◽

Differential Diagnosis ◽

Case Report ◽

Osteoid Osteoma ◽

Excisional Biopsy ◽

Definitive Diagnosis ◽

Diagnosis And Treatment ◽

X Ray ◽

Nocturnal Pain ◽

Prompt Diagnosis

Introduction. Osteoid osteoma is an uncommon, small, benign, self-limiting, and usually painful tumor of the skeleton. Diagnosis can be straightforward if seen in the usual locations as the femur and the tibia in young adults, who present with nocturnal pain, alleviated by salicylates. The diagnosis can be more challenging in the spine, pelvis, hand, or feet. Case Report. We report the case of an 11-year-old boy who was treated symptomatically for a painful toe since 10 months, without a definitive diagnosis. X-ray, MRI, and scintigraphy, along with the typical nocturnal pain and swelling of the toe, suggested an osteoid osteoma, confirmed by histology after excisional biopsy of the lesion. Conclusion. Osteoid osteoma should always be included in the differential diagnosis when it comes to nocturnal pain without systemic signs, even in unusual places in children. The awareness should lead to a prompt diagnosis and treatment.

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A challenging complication following SARS-CoV-2 infection: a case of pulmonary mucormycosis

Infection ◽

10.1007/s15010-020-01561-x ◽

2020 ◽

Author(s):

Daniela Pasero ◽

Silvana Sanna ◽

Corrado Liperi ◽

Davide Piredda ◽

Gian Pietro Branca ◽

...

Keyword(s):

Immune Response ◽

Severe Acute Respiratory Syndrome ◽

Fungal Infection ◽

Invasive Fungal Infection ◽

Opportunistic Infections ◽

Immunocompromised Patients ◽

Pulmonary Mucormycosis ◽

First Case

AbstractSevere acute respiratory syndrome coronavirus 2 infection might induce a significant and sustained lymphopenia, increasing the risk of developing opportunistic infections. Mucormycosis is a rare but severe invasive fungal infection, mainly described in immunocompromised patients. The first case of a patient diagnosed with coronavirus disease (COVID-19) who developed a pulmonary mucormycosis with extensive cavitary lesions is here reported. This case highlights how this new coronavirus might impair the immune response, exposing patients to higher risk of developing opportunistic infections and leading to worse outcomes.

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Differential Diagnosis of Pulmonary Fungal Infection and Lung Cancer via 18F-FDG PET/CT: A Retrospective Study

10.21203/rs.3.rs-191078/v1 ◽

2021 ◽

Author(s):

Xin Feng ◽

Chunmei Deng ◽

Xiaofeng Li ◽

Ye Qiu ◽

Jiehua Deng ◽

...

Keyword(s):

Lung Cancer ◽

Differential Diagnosis ◽

Fungal Infection ◽

Fdg Pet ◽

Pathological Examination ◽

Imaging Features ◽

Antigen Test ◽

Fdg Uptake ◽

Pet Ct ◽

Fdg Pet Ct

Abstract Background: There is limited evidence regarding the 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) characteristics of lung fungal (LF) infections with nodules or masses, which are often misdiagnosed as lung cancer (LC) with indications for surgery. We aimed to investigate the PET/CT findings of LF infections with nodules in comparison to those of LC and clarify the diagnostic value of 18F-FDG PET/CT in the differential diagnosis of LF infections.Methods: We enrolled 21 patients who presented with pulmonary nodules or masses on CT, were diagnosed with LF infections, and underwent PET/CT as the LF group and randomly selected 42 patients with LC diagnosed by pathology as the LC group. Clinical and PET/CT imaging data were statistically analyzed.Results: LC was the most common misdiagnosed disease in the LF group (52.38%). There were no significant differences in lung imaging features between the two groups. The levels of white blood cells, neutrophils, and IgG and the positive rates for fungal antigen test in the LF group were significantly higher than those in the LC group (P<0.05). Lung masses larger than 3 cm were more common in the LC group (P<0.05). Overall, 80.95% (17/21) of patients in the LF group showed increased 18F-FDG uptake. There were no significant between-group differences in the maximal standardized uptake value (SUVmax, 8.20 [2.70, 12.95] vs. 8.80 [7.00, 12.38]). In the LF group, eight, five, and eight patients had cryptococcal, Aspergillus, and Talaromyces marneffei infections, respectively, with no significant difference in SUVmax among them (5.10 [1.70, 14.40] vs. 8.20 [1.50, 8.20] vs. 8.50 [5.10, 11.30]). Conclusions: Both LF infection and LC can present with increased 18F-FDG uptake on PET/CT. Thus, it is difficult to distinguish between them according to lung PET/CT and CT manifestations. Patients presenting with pulmonary masses should also be suspected to have fungal infection, even those with an increased SUVmax and simultaneous lymph node and bone involvement; particular attention is needed for patients with abnormal inflammation indexes and fungal antigen test. We should be emphasized preoperative pathological examination and fungal etiology.

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Petrous Apex Lesions: Differential Diagnosis and Treatment

Skull Base ◽

10.1055/s-2006-958613 ◽

2007 ◽

Vol 16 (S 2) ◽

Author(s):

Anna Papadopoulou ◽

Apostolos Papadopoulos ◽

Giorgos Tzindros ◽

Nikolaos Marangos

Keyword(s):

Differential Diagnosis ◽

Diagnosis And Treatment ◽

Petrous Apex

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PERANAN RADIOLOGI PADA KASUS TUMOR WILMS’

Jurnal Radiologi Indonesia ◽

10.33748/jradidn.v4i1.85 ◽

2020 ◽

Vol 4 (1) ◽

pp. 26-33

Author(s):

Galuh Ayu Treswari ◽

Bambang Soeprijanto ◽

Indrastuti Normahayu ◽

Lenny Violetta

Keyword(s):

Differential Diagnosis ◽

Distant Metastasis ◽

Wilms Tumor ◽

Diagnosis And Treatment ◽

Tumor Extension ◽

Abdominal Tumors ◽

Pathology Reports

Wilms’ tumor is the most frequent renal malignancy in childhood with the highest incidence per year, approximately 7,8 cases per 1.000.000in children under 15 years-old and frequently occurred in 2-5 years of age (highest incidences in 3 years-old). There are many differential diagnosis of intra-abdominal tumors and the correct differential diagnosis are detrimental to the prescribed treatments for the patients.Medical imaging along with pathology reports is a precise way to determine the appropriate diagnosis and treatment. Imaging gives information about tumor extension and distant metastasis, especially useful for indicating pre-operative chemotherapy.

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Coexistent Emphysematous Osteomyelitis and Pyelonephritis – A Report of Two Cases

10.25259/ijmsr_18_2019 ◽

2019 ◽

Vol 1 ◽

pp. 121-123

Author(s):

Shruti Kumar ◽

Mansi Verma ◽

Vikas Bhatia ◽

Mahesh Prakash ◽

Lokesh Singh

Keyword(s):

Diagnosis And Treatment ◽

Prompt Diagnosis

Emphysematous osteomyelitis is defined as the presence of intraosseous gas associated with any infection which is a fatal condition if prompt diagnosis and treatment is not provided. It is commonly caused by anaerobes or the members of Enterobacteriaceae family. Here, we report two cases of emphysematous osteomyelitis with coexistent pyelonephritis.

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