scholarly journals Gambaran Faktor-Faktor yang Berhubungan dengan Kecemasan Pasien Kanker Payudara dalam Menjalani Kemoterapi

2017 ◽  
Vol 3 (2) ◽  
pp. 167
Author(s):  
Siti Rahmiati Pratiwi ◽  
Efri Widianti ◽  
Tetti Solehati

ABSTRAK Kanker payudara merupakan penyebab kematian nomor satu dari seluruh jenis kanker yang terjadi pada wanita. Salah satu penanganan kanker payudara adalah dengan menjalani kemoterapi dimana pasien akan mengalami masalah psikologis yaitu kecemasan. Kecemasan yang terjadi dapat dipengaruhi oleh beberapa faktor yaitu ancaman integritas fisik dan ancaman sistem diri. Penelitian ini bertujuan untuk mengetahui gambaran faktor-faktor yang berhubungan dengan kecemasan pasien kanker payudara dalam menjalani kemoterapi di RSUP Dr. Hasan Sadikin Bandung. Jenis penelitian ini adalah deskriptif kuantitatif. Metode pengambilan sampel yang digunakan yaitu accidental sampling, dengan jumlah responden sebanyak 97 orang. Instrumen yang digunakan adalah STAI (State Trait Anxiety Inventory) dan instrumen faktor-faktor yang berhubungan dengan kecemasan dikembangkan dari teori Stuart dan Laraia. Analisis data menggunakan rumus persentase. Hasil penelitian menunjukkan sebagian dari responden mengalami state anxiety sedang (59,8%), dan sebagian responden mengalami trait anxiety sedang (54,6%). Berdasarkan faktor yang mempengaruhi kecemasan, faktor ancaman sistem diri merupakan faktor yang mendominasi kecemasan pada pasien kanker payudara yang menjalani kemoterapi. Ancaman sistem diri yang mendominasi ini dapat memengaruhi  peran dari pasien, sehingga perlu adanya upaya untuk menurunkan kecemasan dengan memperhatikan berbagai faktor yang memengaruhi. Saran bagi perawat dan institusi terkait diharapkan untuk mengkaji lebih lanjut aspek psikososial dan menentukan intervensi selanjutnya untuk mengurangi kecemasan seperti mengajarkan teknik relaksasi, memberi dukungan dan motivasi, serta mendorong pasien untuk melakukan aktivitas fisik.   ABSTRACT Breast cancer is the leading cause of death from all types of cancer that occur in women. On of the treatment of breast cancer is chemotherapy which the patient will experience a psychological problem, such as anxiety. Anxiety can be affected by several factors, there is threat to physical integrity and threat to self-system of patients. The purpose of this research is to determine factors that affect anxiety of breast cancer patients who underwent chemotherapy in RSUP Dr. Hasan Sadikin Bandung. This research used the descriptive quantitative method with 97 participants as a sampling using accidental sampling. STAI (State Trait Anxiety Inventory) and modifying theory of Stuart & Laraia were used to measure factors that affect anxiety. For analyzing the data, it used percentage abbreviation. The results of this research showed that several of participants experienced moderate state anxiety (59,8%), and several participants experienced moderate trait anxiety (54,6%). Based on factors that affect anxiety, the factor of the threat to self-system was the factor which dominates anxiety patients with breast cancer who underwent chemotherapy. This domination of self-system threat can affect the role of patients. Therefore it needs some efforts for decreasing anxiety with giving an attention to several factors which affect anxiety. The nurse and institution are expected to assess further aspects of psychosocial and determine next intervention reduce anxiety, such as teaching relaxation techniques, provide support and motivation, and encourage the patient to perform physical activity. 

1978 ◽  
Vol 46 (3) ◽  
pp. 855-858 ◽  
Author(s):  
Robert A. Reeves ◽  
Ed M. Edmonds ◽  
Dollie L. Transou

A 2 (trait anxiety) × 4 (color) factorial design was used to determine the effects of red, green, yellow, and blue on state anxiety as a function of high and low trait anxiety. The State-Trait Anxiety Inventory was used to assess both trait (A-Trait) and state (A-State) anxiety for the 10 students assigned to each of the eight treatment combinations. High A-Trait students were significantly more anxious while viewing blue, red, and green than were the low A-Trait students and blue produced significantly more state anxiety than did either yellow or green. These results are consistent with state-trait theory and indicate that the effects of color on state anxiety may be confounded with trait anxiety unless the levels of A-Trait are equivalent for each color condition. The role of cultural and individual differences in the relationship between color and emotion and implications for research are discussed.


2020 ◽  
Vol 48 (6) ◽  
pp. 545-550 ◽  
Author(s):  
Ilenia Mappa ◽  
Flavia Adalgisa Distefano ◽  
Giuseppe Rizzo

AbstractObjectivesCoronavirus (COVID-19) is a new respiratory disease that is spreading widely throughout the world. The aim of this study was to evaluate the psychological impact of COVID-19 pandemic on pregnant women in Italy.MethodsWe considered 200 pregnancies attending our antenatal clinic. A questionnaire was sent to each woman in the days of maximum spread of COVID-19. Sectional was finalized to acquire in 18 items maternal characteristics and to test the women’s perception of infection. Section included the State–trait anxiety inventory (STAI) 40 items validated test for scoring trait anxiety (basal anxiety, STAI-T) and state anxiety (related to the ongoing pandemic, STAI-S). An abnormal value of STAI was considered when ≥40.ResultsThe questionnaire was completed by 178 women (89%). Fear that COVID-19 could induce fetal structural anomalies was present in 47%, fetal growth restriction in 65% and preterm birth in 51% of the women. The median value of STAI-T was 37 and in 38.2% of the study group STAI-T score ≥40 was evidenced. STAI-S values were significantly higher with an increase of median values of 12 points (p≤0.0001). There was a positive linear correlation between STAI-T and STAI-S (Pearson=0.59; p≤0.0001). A higher educational status was associated with increased prevalence of STAI-S ≥ 40(p=0.004). Subgrouping women by the other variables considered did not show any further difference.ConclusionsCOVID-19 pandemic induces a doubling of the number of women who reached abnormal level of anxiety. These findings validate the role of the remote use of questionnaire for identifying women at higher risk of anxiety disorders allowing the activation of support procedures.


2020 ◽  
Author(s):  
Lindsey M. Shain ◽  
Maryland Pao ◽  
Mary V. Tipton ◽  
Sima Zadeh Bedoya ◽  
Sun J. Kang ◽  
...  

Author(s):  
Partha Basu ◽  
Richa Tripathi ◽  
Ravi Mehrotra ◽  
Koninika Ray ◽  
Anurag Srivastava ◽  
...  

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Eui Jung Moon ◽  
Stephano S. Mello ◽  
Caiyun G. Li ◽  
Jen-Tsan Chi ◽  
Kaushik Thakkar ◽  
...  

AbstractHypoxia plays a critical role in tumor progression including invasion and metastasis. To determine critical genes regulated by hypoxia that promote invasion and metastasis, we screen fifty hypoxia inducible genes for their effects on invasion. In this study, we identify v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (MAFF) as a potent regulator of tumor invasion without affecting cell viability. MAFF expression is elevated in metastatic breast cancer patients and is specifically correlated with hypoxic tumors. Combined ChIP- and RNA-sequencing identifies IL11 as a direct transcriptional target of the heterodimer between MAFF and BACH1, which leads to activation of STAT3 signaling. Inhibition of IL11 results in similar levels of metastatic suppression as inhibition of MAFF. This study demonstrates the oncogenic role of MAFF as an activator of the IL11/STAT3 pathways in breast cancer.


Antioxidants ◽  
2021 ◽  
Vol 10 (2) ◽  
pp. 205
Author(s):  
Carmen Griñan-Lison ◽  
Jose L. Blaya-Cánovas ◽  
Araceli López-Tejada ◽  
Marta Ávalos-Moreno ◽  
Alba Navarro-Ocón ◽  
...  

Breast cancer is the most frequent cancer and the leading cause of cancer death in women. Oxidative stress and the generation of reactive oxygen species (ROS) have been related to cancer progression. Compared to their normal counterparts, tumor cells show higher ROS levels and tight regulation of REDOX homeostasis to maintain a low degree of oxidative stress. Traditionally antioxidants have been extensively investigated to counteract breast carcinogenesis and tumor progression as chemopreventive agents; however, there is growing evidence indicating their potential as adjuvants for the treatment of breast cancer. Aimed to elucidate whether antioxidants could be a reality in the management of breast cancer patients, this review focuses on the latest investigations regarding the ambivalent role of antioxidants in the development of breast cancer, with special attention to the results derived from clinical trials, as well as their potential use as plausible agents in combination therapy and their power to ameliorate the side effects attributed to standard therapeutics. Data retrieved herein suggest that antioxidants play an important role in breast cancer prevention and the improvement of therapeutic efficacy; nevertheless, appropriate patient stratification based on “redoxidomics” or tumor subtype is mandatory in order to define the dosage for future standardized and personalized treatments of patients.


2018 ◽  
pp. 1-9
Author(s):  
Jin You ◽  
Qian Lu ◽  
Michael J. Zvolensky ◽  
Zhiqiang Meng ◽  
Kay Garcia ◽  
...  

Purpose Literature has documented the prevalence of anxiety and its adverse effect on quality of life among patients with breast cancer from Western countries, yet cross-cultural examinations with non-Western patients are rare. This cross-cultural study investigated differences in anxiety and its association with quality of life between US and Chinese patients with breast cancer. Methods Patients with breast cancer from the United States and China completed measures for anxiety (Spielberger State-Trait Anxiety Inventory) and quality of life (Functional Assessment of Cancer Therapy-Breast). Results After controlling for demographic and medical characteristics, Chinese patients reported higher levels of trait and state anxiety than US patients. Although there was an association between anxiety and quality of life in both groups of patients, the association between state anxiety and quality of life was stronger among Chinese patients than among US patients, with the association between trait anxiety and quality of life the same between the two cultural samples. Conclusion These findings suggest that anxiety and its association with quality of life among patients with breast cancer varies depending on cultural context, which reveals greater anxiety and poorer quality of life among Chinese patients compared with US patients. This suggests greater unmet psychosocial needs among Chinese patients and highlights the need to build comprehensive cancer care systems for a better quality of life in Chinese populations.


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