scholarly journals A cross sectional study of in-hospital cases of Pediatric Tuberculosis detected by CBNAAT at a tertiary care teaching hospital of Central India.

2021 ◽  
Vol 8 (1) ◽  
pp. 39-44
Author(s):  
Dr. Munindra Pratap Singh ◽  
◽  
Dr. Pawan Kumar Sharma ◽  
Dr. Pradeep Upadhyay ◽  
Dr. Puneet Agrawal ◽  
...  
Keyword(s):  
Tertiary Care ◽  
Central India ◽  
Cross Sectional Study ◽  
Diagnostic Methods ◽  
Gastric Aspirate ◽  
Sectional Study ◽  
Cross Sectional ◽  
Mdr Tb ◽  
Pediatric Tuberculosis ◽  
Low Sensitivity

Background: Childhood tuberculosis is difficult in the identification of the organism due to impropersampling as well as low sensitivity of the smear. Newer diagnostic methods like Cartridge basednucleic acid amplification tests (CBNAAT) can rapidly identify Mycobacterium tuberculosis withimproved sensitivity over the smear testing. Material & Method:This observational record basedcross-sectional study was undertaken to identify the epidemiology of tubercular infection in childrendiagnosed with CBNAAT. The study was carried out by analyzing the data of children from six monthsto 18 years who were diagnosed with Tuberculosis and treated with anti-tuberculosis therapy (ATT)from April 2018 to March 2020. Results: Data of a total of 166 patients was analyzed. 42% ofoverall collected samples were reactive to CBNAAT testing for tuberculosis. 40 gastric aspiratesamples were collected and only four (10%) turned reactive for tuberculosis by CBNAAT. None of thepediatric samples was positive for MDR TB. 66% of children completed treatment and 33% weredeclared cured. Conclusion: 42% positivity after CBNAAT testing for tuberculosis infection incollected samples of sputum and gastric aspirate where only 10% yield in GA samples.

Changing Clinicoradiologic Spectrum of Intracranial Neurotuberculosis in Children: A Cross-sectional Study

2020 ◽  
Vol 35 (13) ◽  
pp. 879-888
Author(s):  
Sumiti Banga ◽  
Chandrika Azad ◽  
Rekha Gupta ◽  
Nishit Sawal ◽  
Vidushi Mahajan ◽  
...  
Keyword(s):  
Nucleic Acid ◽  
Care Center ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Nucleic Acid Amplification Test ◽  
Nucleic Acid Amplification ◽  
Gastric Aspirate ◽  
Sectional Study ◽  
Tubercular Meningitis ◽  
Cross Sectional

Background: Neurotuberculosis is among the most severe type of tuberculosis with high mortality and morbidity in all age groups. Various sociodemographic and disease-/treatment-related factors have emerged over the years that can affect clinical and radiologic features of neurotuberculosis. Objective: To investigate various clinical and neuroradiologic presentations of neurotuberculosis. Methodology: This cross-sectional study was done in a tertiary care center of northern India. The patients between the ages of 3 months and 18 years with newly diagnosed neurotuberculosis were enrolled after taking informed consent. Results: A total of 78 patients (37% males) were enrolled. Fifty-six patients (72%) had tubercular meningitis (TBM) and 22 (28%) isolated tuberculomas. Very high percentage of patients in both the groups was BCG vaccinated. In the tubercular meningitis group, fever (68%), headache (59%), and vomiting (54%) were the most common complaints whereas in the tuberculoma group, seizures (95.5%) were the main complaint and systemic symptoms were rare. In tubercular meningitis patients, cerebrospinal fluid–based studies showed cartridge-based nucleic acid amplification test (Xpert MTB/RIF) positivity for Mycobacterium tuberculosis in 17.6% cases, whereas on gastric aspirate and sputum examination, acid-fast bacilli were seen in 30.7% and cartridge-based nucleic acid amplification test was positive in 19% patients. On neuroimaging, hydrocephalus was seen in 44.6% of tubercular meningitis patients, infarcts in 32%, and basal exudates in 12% patients only; coexistent tuberculomas were seen in 53%. Conclusion: Compared with the available literature, the present study showed a smaller percentage of children <5 years of age, stage III tubercular meningitis cases, and typical neuroradiologic findings like hydrocephalus and basal exudates and more tuberculomas associated with tubercular meningitis.

scholarly journals BREAST FEEDING PRACTICES AND LACTATIONAL COUNSELLING AT A TERTIARY CARE CENTRE OF CENTRAL INDIA.

2020 ◽  
pp. 57-59
Author(s):  
Ankur Singhai ◽  
Swadesh Kumar Verma
Keyword(s):  
Tertiary Care ◽  
Central India ◽  
Cross Sectional Study ◽  
Child Rearing ◽  
Care Centre ◽  
Sectional Study ◽  
Tertiary Care Centre ◽  
Cross Sectional ◽  
Institutional Deliveries ◽  
Breastfeeding Rates

Breast milk is the most ideal and valuable food for the growing infant since it suffices most of the nutritional requirements if given adequately and in appropriate manner. The aim of the study is to assess the knowledge, attitude and practices of mother regarding lactation and impact of counselling to mothers. A questionnaire based cross sectional study was planned and the patients were divided in groups. Statistical analysis was done using IBM SPSS version 22 software.Chi square/Fisher Extract/Student t test and ANOVA test had been used. Most of the ladies had initiated early breastfeeding in both the groups.Hospital staff and family support were the key components influencing the knowledge of breastfeeding.Successful breastfeeding is an important child rearing skill to be learnt and practiced. More IEC activities targeted to promote institutional deliveries will give more opportunity for lactation counselling besides various other advantages like reducing MMR, NMR thus marching towards achieving millennium development goals.We recommend that in every hospital where deliveries are happening, employment of trained lactation counsellors should be made mandatory to improve breastfeeding rates.

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