scholarly journals Influence of cigarette smoking on bone mineral density in postmenopausal women with estrogen deficiency in menstrual history

2014 ◽  
Vol 4 (1) ◽  
pp. 26-30
Author(s):  
Amila Kapetanović ◽  
Dijana Avdić
Keyword(s):  
Bone Mineral Density ◽  
Cigarette Smoking ◽  
Postmenopausal Women ◽  
Bone Mineral ◽  
Linear Correlation ◽  
Estrogen Deficiency ◽  
Control Group ◽  
Mineral Density ◽  
T Score ◽  
Menstrual History

Introduction: Estrogen deficiency leads to bone mass loss and increased risk for osteoporosis. The aim of this study was to examine influence of cigarette smoking on bone mineral density in postmenopausal women with estrogen deficiency in menstrual history.Methods: The total of 100 postmenopausal women living in Sarajevo area, aged 50-65 years, with estrogen deficiency in menstrual history participated in this prospective study. The subjects were divided in two groups, examination and control group, based on bone mineral density values. The women in the examination group had osteoporosis while in the control group were women with osteopenia or normal bone mineral density. Bone mineral density was measured at the lumbar spine and proximal femur by Dual–Energy X–ray Absorptiometry using Hologic QDR-4000 scanner. Smoking habits were assessed for each subject.Results: The average number of cigarettes smoked per day in women with estrogen deficiency in menstrual history was 14.86 in the examination group and 4.67 in the control group. The difference in the average number of cigarettes smoked per day between the two groups was statistically significant (p <0.01). The coefficient of linear correlation between T score and the number of cigarettes smoked per day among women with estrogen deficiency in menstrual history in the examination group was statistically significant (p<0.01). The coefficient of linear correlation between T score and the number of cigarettes smoked per day among women with estrogen deficiency in menstrual history in the control group was statistically significant ( p<0.05).Conclusion: Results of this study suggest that cigarette smoking has negative impact on bone mineral density and that healthy lifestyle (no smoking) has the potential to reduce bone loss in postmenopausal women with estrogen deficiency in menstrual history.

scholarly journals Influence of coffee consumption on bone mineral density in postmenopausal women with estrogen deficiency in menstrual history

2014 ◽  
Vol 4 (2) ◽  
pp. 105-109 ◽  
Author(s):  
Amila Kapetanović ◽  
Dijana Avdic
Keyword(s):  
Bone Mineral Density ◽  
Postmenopausal Women ◽  
Bone Mineral ◽  
Daily Intake ◽  
Coffee Consumption ◽  
Estrogen Deficiency ◽  
Control Group ◽  
Mineral Density ◽  
Average Daily Intake ◽  
Menstrual History

Introduction: Complex etiology of osteoporosis include genetic, hormonal, environmental and nutritional factors. The aim of this study was to examine influence of coffee consumption on bone mineral density in postmenopausal women with estrogen deficiency in menstrual history.Methods: This prospective study included 100 postmenopausal women, aged 50-65 years living in Sarajevo area, with estrogen deficiency in their menstrual history. The controlled clinical trials were conducted. Two groups were formed (based on bone mineral density values). The examination group included 50 women who had osteoporosis, while the control group included 50 women without osteoporosis (osteopenia, normal bone mineral density). The lumbar spine and proximal femur bone mineral density was measured by Dual–Energy X–ray Absorptiometry using Hologic QDR-4000 scanner. Coffee drinking habits were assessed for each subject.Results: The average daily intake of coffee in women with estrogen deficiency in menstrual history was at 267.6 ml in the examination group and in the control group 111.6 ml. The difference in the average daily intake of coffee between the two groups was statistically significant (p < 0.001). There was registered significant correlation between intake of coffee and bone mineral density in examination (p < 0.01) and in control group (p < 0.05).Conclusion: This study indicates that coffee consumption is a risk factor for osteoporosis in postmenopausal women, aged 50-65 years living in Sarajevo area, with estrogen deficiency in their menstrual history. It was shown that the effects of coffee on bone mineral density are dose-dependent.

scholarly journals Physical activity and bone mineral density in postmenopausal women without estrogen deficiency in menstrual history

2013 ◽  
Vol 3 (3) ◽  
pp. 205-209
Author(s):  
Amila Kapetanović ◽  
Dijana Avdić
Keyword(s):  
Physical Activity ◽  
Bone Mineral Density ◽  
Bone Density ◽  
Postmenopausal Women ◽  
Bone Mineral ◽  
Control Group ◽  
Mineral Density ◽  
Menstrual History ◽  
History Of ◽  
Mineral Bone Density

Introduction: The estrogen defi ciency after menopause leads to accelerated loss of bone mass. The aim of this study was to examine influence of physical activity on bone mineral density in postmenopausal women who hadn’t a deficit of estrogen in their menstrual history.Methods: This prospective study included 100 postmenopausal women, ages between 50 and 65, living in Sarajevo area without estrogen deficiency in menstrual history. The women in the examination group had osteoporosis. The women in the control group had osteopenia or normal mineral bone density. Mineral bone density was measured at the lumbar spine and proximal femur by Dual–Energy X–ray Absorptiometry using Hologic QDR-4000 scanner. To assess level of physical activity an International Physical Activity Questionnaire - Long Form was used.Results: In the examination group of women who had no history of menstrual estrogen deficit, level of physical activity was low in 52.00% female, and in 48.00% women level of physical activity was moderate. In the control group of women who had no history of menstrual estrogen defi cit in 10.00% female level of physical activity was low, and in 90.00% female level of physical activity was moderate. The difference in levels of physical activity between the two groups was statistically significant, X2 test = 20.6, p <0.005.Conclusion: Results of this study suggest that moderate physical activity has positive impact on bone mineral density in postmenopausal women without estrogen defi ciency in menstrual history and has the potential to reduce rapid bone loss after menopause.

scholarly journals Effect of Denosumab on Bone Mineral Density and Markers of Bone Turnover among Postmenopausal Women with Osteoporosis

2016 ◽  
Vol 2016 ◽  
pp. 1-6 ◽  
Author(s):  
A. Sánchez ◽  
L. R. Brun ◽  
H. Salerni ◽  
P. R. Costanzo ◽  
D. González ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Bone Turnover ◽  
Postmenopausal Women ◽  
Bone Mineral ◽  
Bone Turnover Markers ◽  
Control Group ◽  
Bone Resorption Marker ◽  
Similar Response ◽  
Mineral Density ◽  
Turnover Markers

The aim of this study was to evaluate the effect of denosumab (Dmab) on bone mineral density (BMD) and bone turnover markers after 1 year of treatment. Additionally, the effect of Dmab in bisphosphonate-naïve patients (BP-naïve) compared to patients previously treated with bisphosphonates (BP-prior) was analyzed. This retrospective study included 425 postmenopausal women treated with Dmab for 1 year in clinical practice conditions in specialized centers from Argentina. Participants were also divided according to previous bisphosphonate treatment into BP-naïve and BP-prior. A control group of patients treated with BP not switched to Dmab matched by sex, age, and body mass index was used. Data are expressed as mean ± SEM. After 1 year of treatment with Dmab the bone formation markers total alkaline phosphatase and osteocalcin were significantly decreased (23.36% and 43.97%, resp.), as was the bone resorption marker s-CTX (69.61%). Significant increases in BMD were observed at the lumbar spine, femoral neck, and total hip without differences between BP-naïve and BP-prior. A better BMD response was found in BP-prior group compared with BP treated patients not switched to Dmab.Conclusion. Dmab treatment increased BMD and decreased bone turnover markers in the whole group, with similar response in BP-naïve and BP-prior patients. A better BMD response in BP-prior patients versus BP treated patients not switched to Dmab was observed.

scholarly journals Pemberian Kalium Buah Pisang Lampung terhadap Densitas Mineral Tulang pada Lansia

2019 ◽  
Vol 5 (1) ◽  
pp. 30
Author(s):  
Edy Waliyo ◽  
Nopriantini Nopriantini ◽  
Shelly Festilia Agusanty
Keyword(s):  
Bone Mineral Density ◽  
Bone Mineral ◽  
Random Sampling ◽  
The Elderly ◽  
Control Group ◽  
Mineral Density ◽  
Control Group Design ◽  
Separate Sample ◽  
Group Design ◽  
T Score

Abstract: Effect of Lampung Banana Potassium on Bone Mineral Density in the Elderly. This study aims to determine the effect of banana lampung on bone mineral density in the elderly in the Social Welfare Tresna Werdha and Werdha Graha Kasih Father’s home). This research is a research with experimental design with the separate sample pretest posttest control group design. The research was carried out in the Tresna Werdha Social Institution and the Werdha Graha Kasih Father’s house, from May to July 2017. The sampling technique was taken by random sampling The result of potassium feeding on 150 grams of banana per day for 30 days by increasing BMD T-score of 0.17 while in control group (without banana lampung) BMD T-score decreased by - 0.32. After intervention in both groups showed a difference of BMD T-score of 0.49. Abstrak: Pemberian Kalium Buah Pisang Lampung terhadap Densitas Mineral Tulang pada Lansia. Penelitian ini bertujuan untuk mengetahui mengetahui pengaruh pemberian buah pisang lampung terhadap bone mineral density pada lansia di wilayah Panti Sosial Tresna Werdha dan panti Werdha Graha Kasih Bapa). Penelitian yang dilakukan ini adalah penelitian dengan desain eksperimen dengan rancangan the separate sample pretest posttest control group design. Penelitian dilaksanakan di wilayah Panti Sosial Tresna Werdha dan panti Werdha Graha Kasih Bapa), mulai bulan Mei s/d Juli 2017. Teknik sampling diambil dengan cara random sampling Hasil pemberian kalium pada buah pisang lampung sebanyak 150 gr setiap hari selama 30 hari dengan dapat meningkatkan BMD T-score sebesar 0,17 sedangkan pada kelompok control (tanpa pemberian buah pisang lampung) BMD T-score menurun sebesar - 0,32. Setelah intervensi pada ke dua kelompok menunjukkan adanya perbedaan BMD T-score sebesar 0,49.

scholarly journals Influence of Number of Parity on Bone Mineral Density among Postmenopausal Women

2016 ◽  
Vol 33 (2) ◽  
pp. 75-78
Author(s):  
Irin Parveen Alam ◽  
Mohd Azharul Haque ◽  
Saleha Begum Chowdhury
Keyword(s):  
Bone Mineral Density ◽  
Postmenopausal Women ◽  
Bone Mineral ◽  
Significant Negative Correlation ◽  
Common Disease ◽  
Mineral Density ◽  
T Score ◽  
Femur Neck ◽  
Considerable Morbidity ◽  
Age Range

Introduction- Osteoporosis is a common disease of postmenopausal women and is responsible for considerable morbidity and mortality. The most important single determining factor is low bone mass. Generally accepted risk factors of osteoporosis in women are low body weight, age, low physical activity and cigarette smoking. The effect of parity is controversial.Objective-The main objective of the study was to assess the influence of parity on bone mineral density among the postmenopausal women.Methods-In this study total 75 postmenopausal women aged 51-70 years of with parity 1-13 were studied. Parity was described as the number of births reported by the women. In Journal of Bangladesh College of Physicians and Surgeons Vol. 33, No. 2, April 2015 this study T score of BMD of different bony sites lumber vertebrae and femur were analyzed. BMD were measured in the Institute of Nuclear Medicine at BSMMU. Correlations between BMD values with parity were detected.Results- The mean age of the patients was 60 years with a standard deviation of ±9.32 years. All patients were within 51 to 70 years age range. A significant negative correlation was found in present study between parity and the T score measurement results obtained from L2, L3, L4, L2-4, Femur neck, Trochantor and Ward’s triangle. This shows mean Tscore of BMD were more negative as number of parity increases.J Bangladesh Coll Phys Surg 2015; 33(2): 75-78Introduction- Osteoporosis is a common disease of postmenopausal women and is responsible for considerable morbidity and mortality. The most important single determining factor is low bone mass. Generally accepted risk factors of osteoporosis in women are low body weight, age, low physical activity and cigarette smoking. The effect of parity is controversial. Objective-The main objective of the study was to assess the influence of parity on bone mineral density among the postmenopausal women. Methods-In this study total 75 postmenopausal women aged 51-70 years of with parity 1-13 were studied. Parity was described as the number of births reported by the women. In Journal of Bangladesh College of Physicians and Surgeons Vol. 33, No. 2, April 2015 this study T score of BMD of different bony sites lumber vertebrae and femur were analyzed. BMD were measured in the Institute of Nuclear Medicine at BSMMU. Correlations between BMD values with parity were detected. Results- The mean age of the patients was 60 years with a standard deviation of ±9.32 years. All patients were within 51 to 70 years age range. A significant negative correlation was found in present study between parity and the T score measurement results obtained from L2, L3, L4, L2-4, Femur neck, Trochantor and Ward’s triangle. This shows mean Tscore of BMD were more negative as number of parity increases.J Bangladesh Coll Phys Surg 2015; 33(2): 75-78

scholarly journals Comparison of Bone Mineral Density, T-Scores and Serum Zinc between Diabetic and Non Diabetic Postmenopausal Women with Osteoporosis

2015 ◽  
Vol 7 (01) ◽  
pp. 043-048 ◽  
Author(s):  
Priyanka R Siddapur ◽  
Anuradha B Patil ◽  
Varsha S Borde
Keyword(s):  
Bone Mineral Density ◽  
Fracture Risk ◽  
Postmenopausal Women ◽  
Bone Mineral ◽  
Mineral Density ◽  
T Score ◽  
Increased Risk ◽  
Serum Zn ◽  
Type 2 Diabetic

ABSTRACT Context: Postmenopausal osteoporosis is a public health problem. Diabetics are at increased risk of osteoporosis-related fractures. Zinc (Zn) has a role in collagen metabolism, and its levels are altered in diabetes. Aims: The aim was to compare bone mineral density (BMD), T-score and serum Zn between diabetic and nondiabetic postmenopausal women with osteoporosis to see if they influence increased fracture risk in diabetes. Settings and Design: It is a cross-sectional study conducted at Department of Biochemistry, Jawaharlal Nehru Medical College, Belgaum. Materials and Methods: Thirty type 2 diabetic and 30 age-matched (aged 45-75 years) nondiabetic Dual energy X-ray absorptiometry (DEXA) confirmed postmenopausal osteoporotics were included from January 2011 to March 2012. Serum Zn was analyzed by atomic absorption spectrophotometry. Statistical Analysis Used: Mean and standard deviation of the parameters of the two groups were computed and compared by unpaired Student's t-test. Relationship between variables was measured by Karl Pearson's correlation co-efficient. A statistical significance is set at 5% level of significance (P < 0.05). Results: T-score was significantly higher in diabetics compared with nondiabetics(−2.84 ± 0.42 vs. −3.22 ± 0.74) P < 0.05. BMD and serum Zn of diabetics showed a significant positive correlation with body mass index (BMI). Conclusions: Type 2 diabetic postmenopausal osteoporotics have a higher T-score than the nondiabetics. High BMI in type-2 diabetes mellitus (T2DM) may contribute to high BMD and may be a protective factor against zincuria. Increased fracture risk in T2DM could be due to other factors like poor bone quality due to hyperglycemia rather than BMD. Strict glycemic control is of paramount importance.

scholarly journals Bone mineral density status and the need for anti-osteoporotic therapy in postmenopausal women with systemic scleroderma

2019 ◽  
pp. 72-79
Author(s):  
O. V. Dobrovolskaya ◽  
N. V. Demin ◽  
A. V. Smirnov ◽  
N. V. Toroptsova
Keyword(s):  
Bone Mineral Density ◽  
Postmenopausal Women ◽  
Bone Mineral ◽  
Systemic Scleroderma ◽  
Control Group ◽  
Inflammatory Rheumatic Diseases ◽  
Mineral Density ◽  
Buffer Solution ◽  
Identification Of Persons ◽  
The One

The article is devoted to the study of bone mineral density in patients with systemic scleroderma (SSD) and the identification of persons, who needs the anti-osteoporotic treatment. A total of 170 postmenopausal women were examined: 103 patients with SSD and 67 patients without inflammatory rheumatic diseases. Osteoporosis (OP) was detected in 49.5% in the patient group and in 31% in the control group (p <0.05). The correlation relation between the bone mineral density (BMD) and body mass index was found to be direct, and the one between BMD and the duration of the disease and the cumulative dose of glucocorticoids was found to be inverse. The blood vitamin D level (25(OH)D) was significantly lower in patients than in controls (19.3 ± 7.4 ng/ml and 23.3 ± 8.6 ng/ml, respectively), and among individuals with SSD it was significantly lower in patients with OP than in patients without OP (p <0.05). 85% examined patients with SSD needed the anti-osteoporotic therapy. Treatment with the generic alendronate in the form of effervescent tablets to prepare Binosto buffer solution was effective and safe in patients with SSD with esophageal hypotension.

Cigarette Smoking, Alcohol and Caffeine Consumption, and Bone Mineral Density in Postmenopausal Women

1998 ◽  
Vol 8 (4) ◽  
pp. 355-363 ◽  
Author(s):  
M. J. Grainge ◽  
C. A. C. Coupland ◽  
S. J. Cliffe ◽  
C. E. D. Chilvers ◽  
D. J. Hosking
Keyword(s):  
Bone Mineral Density ◽  
Cigarette Smoking ◽  
Postmenopausal Women ◽  
Bone Mineral ◽  
Mineral Density ◽  
Caffeine Consumption

scholarly journals Prevalence of premenopausal osteoporosis in hypothyroid patients

2020 ◽  
Vol 7 (3) ◽  
pp. 431
Author(s):  
Arvind C. ◽  
Ragul B. ◽  
Sudha M.
Keyword(s):  
Bone Mineral Density ◽  
Bone Mineral ◽  
Qualitative Data ◽  
Statistical Significance ◽  
Lumbar Vertebra ◽  
Control Group ◽  
High Dose ◽  
Mineral Density ◽  
Neck Of Femur ◽  
T Score

Background: Hypothyroidism alone is not a risk factor for osteoporosis but the patient on treatment with levothyroxine in chronic terms have the greater chances of osteoporosis. This study is to evaluate the role of chronic levo-thyroxine treatment on bone mineral density and the development of osteoporosis.Methods: A cross sectional descriptive study in which patients with recently diagnosed as hypothyroidism were taken as the first group and the second group as those who were having hypothyroidism for more than 2 years plus on chronic treatment with levothyroxine. Healthy premenopausal women were the control group. TSH was measured in all and the T score were used to measure osteoporosis severity. T score of lumbar vertebra and neck of femur were used for comparison. The description of qualitative data was done in absolute frequencies and percentages. The description of quantitative data were done as the, mean standard deviation, median, minimum and maximum. In the comparison of qualitative data between groups, the Chi-square test and contingency tables was used by rearranging the percentages of several variables (TSH, t-score). The statistical significance was set p<0.05.Results: TSH levels in the first group were slightly different from rest of the groups. T score were significantly lesser in patients in the second group who are diagnosed with hypothyroidism and on treatment with levothyroxine.Conclusions: The treatment for hypothyroidism with levo thyroxine reduces both TSH and bone mineral density in the study groups. Proper control of risk factors and avoidance of high dose thyroxine supplements are an effective way in prevention of osteoporosis.

scholarly journals The effect of different exercise programs on bone mineral density and physical function in women with osteoporosis: A randomized controlled trial

2017 ◽  
Vol 1 (1) ◽  
pp. 47
Author(s):  
Lumnije Hoxha Kamberi
Keyword(s):  
Bone Mineral Density ◽  
Muscle Strength ◽  
Physical Function ◽  
Postmenopausal Women ◽  
Bone Mineral ◽  
Controlled Trial ◽  
Intervention Group ◽  
Control Group ◽  
Mineral Density ◽  
Significant Difference

Aim: Osteoporosis is a multifactorial progressive skeletal disorder characterized by reduced bone mass. Exercise is widely recommended to reduce osteoporosis, falls and related fragility fractures. The purpose of this study was to investigate the effects of land exercise (LE) and aquatic exercise (AE) on physical function and bone mineral density (BMD). Methods: Fifty-eight postmenopausal women, aged 50-70 years,  diagnosed with osteoporosis according to BMD measures, enrolled in this study. The subjects were randomly assigned to either the intervention group (LE group) or the control group (AE group). Physical function and BMD were assessed in all subjects in both groups before and after 10 months of intervention. The muscle strength,   flexibility, balance, gait time and pain were measured to assess physical function. Bone mineral density at the lumbar spine was measured by dual energy X-ray absorptiometry (DEXA). Results: There were no significant differences between the two groups in the baseline anthropometric data. The two groups were similar with respect to age, weight, height, and body mass index (p>0.05). After the exercise program, muscle strength, flexibility, gait time, pain, and bone density (p<0.001)  significantly improved with LE compared to AE. There was no significant difference between the two groups in balance at the 10-month follow-up. Conclusion: Significant improvements in physical function and BMD suggest that LE is a possible alternative for     postmenopausal women with OP. Clinical rehabilitation impact: In the current  available literature there is insufficient data regarding combined regimens,       additionally, conclusions from our research can inspire further studies in order to promote land and water based exercise.

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