Like a growing number of individuals, the author believes that business is facing the same bifurcation point physics was facing before the development of quantum mechanics – trying to fit a Newtonian explanation onto a non-Newtonian problem. Given that perspective business needs a system-based model not more research and development on its Newtonian practices and beliefs. The focus of this paper focuses is on the development of such a framework. This paper draws on science to identify the necessary requirements for a living system and converts that into a three-entity framework. Through the conversion of this living-system framework the necessary requirements for a living business system are identified. With that, an assortment of currently available system-based business tools and techniques that fulfill most of the requirements of a living business system, are introduced. An approach to implementing these tools and techniques as well as remaining open for the incorporation of other systems-based practices is presented.