scholarly journals A Ring-Based Cybersecurity Architecture for Critical Infrastructure

Author(s):  
Sarayut Chaisuriya Et al.

A defense-in-depth (DID) approach for securing critical information infrastructure has been a common method used in cybersecurity. However, holistic design guidelines are lacking which precludes organizations from adopting them. Therefore, this paper sets out to outline and detail a holistic framework using ring-based nested network zone architecture for the design and implementation of highly secured networked environments. The proposed cybersecurity architecture framework offers a structural design for holistically designed N-tier system architectures. Several implementation options, including zoning perimeters, are suggested as being capable of offering different security capability levels by trading off amongst various security aspects. Also, the proposed architecture allows adaptability in implementations for various real-world networks. This paper also proposes an attack-hops verification approach to evaluate the architectural design.

2019 ◽  
Vol 17 (3) ◽  
pp. 260-283 ◽  
Author(s):  
Maciej Nisztuk ◽  
Paweł B. Myszkowski

The article presents the application of Hybrid Evolutionary and Greedy-based algorithms to the problem of Automated Floor Plan Generation. The described optimization issue is part of a wider domain of Computer-Aided Architectural Design. The article covers the extensive description of the representation domain model (architectural canonical guidelines, user design requirements and constraints) and the explanation of proposed approach: problem representation, genetic algorithm operators, and fitness function definition. The research experimental procedures are based on real-world data: the architectural design guidelines being the design constraints and five real-world functional programs introduced and proposed as benchmarks. The article summarizes the implementation of the proposed approach, compares the Hybrid Evolutionary Algorithm experimental results with the Greedy-based algorithm, and suggests possible extensions and future research directions.


2004 ◽  
Author(s):  
Kathryn Roose ◽  
Jacob Birmingham ◽  
Phillip Dykstra ◽  
Tom Kile ◽  
Mark Heck

2015 ◽  
Vol 31 (1) ◽  
pp. 29-49 ◽  
Author(s):  
Anne Abraham ◽  
Hazel Jones

ABSTRACT With the emergence of new sets of technological tools, university students are now offered more authentic learning experiences involving real-world, complex problems and their solutions. This focus on problem-based activities and case studies has produced a learning environment that is inherently multidisciplinary. This paper reports on the development of a scaffolded learning assignment with blended components applied in an accounting subject that was taught in a cross-disciplinary setting. The assignment was developed in a sociocultural context, based on a Vygotskian approach, and this paper details its design and development. The five stages of the assignment were carefully scaffolded and included elements of individual and group tasks, finishing with an individual reflection on the process. Formative assessment and associated feedback are important elements of the scaffolding and thus the paper reports both the design and implementation of the assignment, and provides qualitative feedback from students regarding how completing the assignment enhanced their learning in accounting. The paper concludes with suggestions for further applications for the learning design of the assignment.


2013 ◽  
Vol 756-759 ◽  
pp. 1715-1719
Author(s):  
Hui Bo Song ◽  
Yong Wang ◽  
Kai Li ◽  
Mei Lin Liu ◽  
Bing Zhan Ma

Nowadays, it is particularly important to improve the level of backup devices management for enterprises, because a reasonable management mechanism would ensure a business operation normally. The paper presents a backup device management system in detail, including requirements analysis, architectural design, function modules and implementation mechanism, which provides basis for systems implementation and application. The system we designed can manage backup devices dynamically, which gives support to the improvement and maintenance, and also provides more convenience for users.


1982 ◽  
Vol 26 (2) ◽  
pp. 203-203
Author(s):  
James A. Wise

This is a panel session focused on the applications of Human Factors to real world problems in architectural design. Five representatives from various design & research professions will present recent case studies of theirs, and examine the contribution that Human Factors made to these projects. The diversity of their examples shows the usefulness and importance on integrating concerns for the human user into plans for the built environment.


2021 ◽  
Vol 263 (5) ◽  
pp. 1130-1141
Author(s):  
Kivanc Kitapci ◽  
Dogukan Ozdemir

One of the objectives of architectural design is to create multi-sensory environments. The users are under the influence of a wide variety and intense perceptual data flow when users experience a designed space. Architects and environmental designers should not ignore the sense of hearing, one of the most important of the five primitive senses that allow us to experience the physical environment within the framework of creative thinking from the first stage of the design process. Today, auditory analysis of spaces has been studied under architectural acoustics, soundscapes, multi-sensory interactions, and sense of place. However, the current sound design methods implemented in the film and video game industries and industrial design have not been used in architectural design practices. Sound design is the art and application of making soundtracks in various disciplines and it involves recognizing, acquiring, or developing of auditory components. This research aims to establish a holistic architectural sound design framework based on the previous sound classification and taxonomic models found in the literature. The proposed sound design framework will help the architects and environmental designers classify the sound elements in the built environment and provide holistic environmental sound design guidelines depending on the spaces' functions and context.


2020 ◽  
Vol 29 (3) ◽  
pp. 154-160 ◽  
Author(s):  
Michael Rose ◽  
Katrin Maibaum

As transdisciplinary and transformative research approaches, real-world laboratories (RwLs) come with many pitfalls. Their design and implementation place high demands on everyone involved, which means that realistically, things rarely go smoothly. The following Design Report shares the lessons learned about establishing and adjusting communication and organisational structures in RwLs.What should we take into account when setting up real-world laboratories (RwLs)? In our analysis of the experience of (co-)designing three RwLs within the Well-Being Transformation Wuppertal research project, we examine both the origin of the project proposal and its implementation, from management, communication and inter- and transdisciplinarity to actor dynamics and recruitment criteria for staff. We especially highlight the effects of the initial co-design phase (project proposal) on the RwL’s implementation, focusing on the challenges which arose and how these were addressed.We conducted 19 semi-structured interviews, analysed relevant project documentation and reflected on the research team’s own experiences. The transdisciplinary and transformative dimensions of the RwL approach are the areas where significant lessons were learned. RwLs are unique in their extraordinarily strong need to balance different roles and resources, even as many of their challenges and solutions resemble those which also arise in transdisciplinary research. The uniqueness of RwLs lies in their objective to co-produce not only socially robust knowledge but also tangible real-world change through experimentation.


2019 ◽  
Vol 12 ◽  
pp. 71-78
Author(s):  
Obidimma Ezezika

Experiential learning has the potential to enhance students’ success and prepare them for the job market, including through class experiences that mirror experiences in the workforce. In this article, I lay out the process of incorporating experiential learning in a global health course. I have derived three key lessons from the design and implementation of this course: focus on one overarching goal, align learning activities with real world expectations, and help students understand connections between their projects and course content. These lessons provide insights to integrate experiential learning activities in the classroom.   L’apprentissage expérientiel a le potentiel d’améliorer la réussite des étudiants et de les préparer pour le marché du travail, notamment en créant en classe des expériences qui ressemblent aux expériences en milieu de travail. Dans cet article, je présente le processus d’incorporation de l’apprentissage expérientiel dans un cours sur la santé mondiale. Je tire trois leçons de la conception et de la mise en œuvre de ce cours : il faut 1) se concentrer sur un objectif primordial, 2) harmoniser les activités d’apprentissage et les attentes du monde réel et 3) aider les étudiants à comprendre les rapports entre leurs projets et le contenu du cours. Ces leçons permettent de mieux comprendre comment incorporer des activités d’apprentissage expérientiel en classe.


2021 ◽  
Vol 39 (15_suppl) ◽  
pp. e18688-e18688
Author(s):  
Victoria Wang ◽  
Chenming Cui ◽  
Lei Yang ◽  
Gerald Li ◽  
Alexa Betzig Schrock ◽  
...  

e18688 Background: Comprehensive genomic profiling (CGP) is an established diagnostic approach to select patients for TT. As CGP gains wide adoption, an increasing number of patients are found to harbor driver mutations for which no approved TT is available. This is often addressed through use of matched TKI and mAb approved for other mutations or anatomic sites. In this work, we examined the clinical efficacy of off-label TT in R/M NSCLC. Methods: Using a de-identified NSCLC clinico-genomic database (CGDB), we identified 6590 NSCLC patients who underwent Foundation Medicine CGP, of whom 17.8% harbored an actionable genomic alteration (GA) for which an FDA-approved TT was available and 2% (133) whose GA (MET ex-14, uncommon EGFRm, EGFR ex20ins, HER2 amp/mut, RET fusion, BRAF class 2/3) lacked an FDA-approved TT (62 in 1L and 71 in ≥2L ) who received matched off-label TT. ESMO Scale for Clinical Actionability (ESCAT) was used to grade levels of evidence. For patients who progressed on initial chemotherapy (range 2 – 9 lines, median 3), we calculated clinical efficacy using the ratio of real world PFS on targeted therapy (rw-PFS2) to rw-PFS on the last prior line of therapy (rw-PFS1) and used a cut-off of PFS2/PFS1 > 1.3 to determine off-label drug efficacy. Results: Of the 133 patients reviewed, 72 were classified as ESCAT level IB (uncommon EGFRm, MET-ex14), 45 IIB (HER2m/amp, EGFR ex-20ins), 7 IC (RET fusions). PFS varied significantly by mutation and line of therapy (table 1) with uncommon EGFRm+ and MET-ex14 exhibiting best response while EGFR ex20 ins, BRAF class 2/3 and HER2 amp fared significantly worse. 55.8% of the patients (39 of 71) reached a PFS2/PFS1 ratio > 1.3 (two-sided 95% CI, 45.3 % – 68.7 %), ranging from 93% in uncommon EGFRm+ down to 20% in HER2 amp and 44% in ex20ins. Conclusions: We provide real-world evidence to assess off-label TT in NSCLC. Clinical benefit derived from off-label TT is unevenly distributed across various mutations with most survival advantage accruing to specific mutations (MET-ex14 and uncommon EGFRm) at the expense of others (HER2 amp). Survival advantage was highly influenced by two factors: A) the timing of CGP with the earlier recipients of genomic profiling achieving better outcome, B) the identity of the driver mutation, highlighting the role of clinical actionability tier system to define level of evidence supporting such intervention.[Table: see text]


Sign in / Sign up

Export Citation Format

Share Document