scholarly journals Influence of the breathing methods of the heated oxygen-helium mixture on the indicators of variability of the heart rhythm and functions of external respiration in military servers with chronic obstructive

2019 ◽  
Vol 18 (6) ◽  
pp. 374-378
Author(s):  
Natalia V. Bobkina ◽  
M. V. Lyadov ◽  
M. Yu. Gerasimenko
Keyword(s):  
Adaptive Systems ◽  
Pulmonary Ventilation ◽  
Heart Rhythm ◽  
Medical Rehabilitation ◽  
Chronic Obstructive ◽  
External Respiration ◽  
Moderate Degree ◽  
Chronic Obstructive Bronchitis ◽  
Helium Mixture ◽  
Hf Wave

The purpose of the research was to study the effectiveness of using heated oxygen-helium mixture in the medical rehabilitation of patients with chronic obstructive bronchitis. Material and methods. The study included 68 patients aged 32 to 56 years (43.7 4.1 years). The first group (n = 33) contained of practically healthy volunteers and the second group (n = 35) of patients with a verified diagnosis: chronic obstructive bronchitis, moderate to moderate degree of obstruction, the duration of the disease ranged from 2 to 16 years (5.4 1.4). In both groups, heated oxygen-helium mixture was used (the temperature of the mixture in the mask was 50С). Patients of the second group 30 minutes before inhalation of the heated oxygen-helium mixture used short or long-acting bronchodilators. The study was carried out before the start of therapy, after 5, 10 procedures. Estimated indicators of heart rate variability and respiratory function. Results and conclusion. The use of heated oxygen-helium mixture allowed to increase the activity of the parasympathetic department of the autonomic nervous system and reduce the tone of the sympathetic department, normalize the functioning of the bodys regulatory systems. The research data showed an increase in SDNN, RMSSD, a decrease in LF/HF wave power, and a decrease in the centralization index. After the 5th breathing procedure of the heated oxygen-helium mixture, the second group showed an increase in external respiration function by an average of 16%, and after a full course, by 20%, which indicates an improvement in pulmonary ventilation and a decrease in the degree of obstructive disorders. The use of heated oxygen-helium mixture is a promising method that does not give complications, can reduce the severity of obstructive syndrome, helps to restore the bodys adaptive systems, and can be used as one of the methods in the comprehensive rehabilitation of patients with chronic obstructive bronchitis.

scholarly journals The use of heated oxygen-helium mixture in patients with chronic obstructive lung disease

2021 ◽  
Vol 20 (1) ◽  
pp. 23-29
Author(s):  
Natalya V. Bobkina ◽  
Maxim V. Lyadov ◽  
Marina Y. Gerasimenko ◽  
Irina V. Zhitareva
Keyword(s):  
Blood Pressure ◽  
Oxygen Consumption ◽  
Emotional State ◽  
Chronic Obstructive Lung Disease ◽  
Physical Exertion ◽  
Step Test ◽  
Chronic Obstructive ◽  
Maximum Oxygen Consumption ◽  
Chronic Obstructive Bronchitis ◽  
Helium Mixture

BACKGROUND: In recent years, along with the development of new pharmacological approaches and treatment COLD (chronic obstructive lung disease), a significant attention is paid to the study of non-medical methods of treatment and correction of the system inflammation occurring. AIMS: To assess the effectiveness of the use of heated oxygen-helium mixture (OHM) in the rehabilitation of patients with chronic obstructive bronchitis on an outpatient polyclinic stage. MATERIALS AND METHODS: The supervision was 102 patients aged from 32 to 56 (43.74.1) years. All patients entered into research signed voluntary informed consent. Patients were divided into three groups: the first group (n=32) is the control; the second group (n=35) is the main one. Patients of these groups had a verified diagnosis: chronic obstructive bronchitis, moderate and moderate degree of obstruction, the duration of the disease amounted to 2 years to 16 (5.41.4) years. The third group (n=35) is practically healthy patients. The patients of the second and third group passed the respiratory course of heated OHM (the temperature of the mixture in the mask 50). Breathing was carried out in cyclical-fractionated mode: the breath of the mixture 5 minutes then breathing with atmospheric air 5 minutes (one cycle), 3 cycles for the procedure. The course of treatment consisted of 1 procedure per day for 10 days from the first day of the study. The clinical efficacy of reducing treatment was assessed before the start of therapy, after the 10th procedure in the following indicators: Harvard step test index, systolic blood pressure (SBP), diastolic blood pressure (DBP), heart rate (heart rate), blood pressure recovery time, maximum oxygen consumption (MOC); diagnosis of psycho-emotional state using WBAM Questionnaire (well-beingactivitymood). RESULTS: In the group of practically healthy patients, a positive dynamics was noted in the speed of adaptive processes for the restoration of the cardiovascular system after physical exertion of the form of a decrease in blood pressure reduction time, a decrease in systolic blood pressure, the indicators of the Harvard step test index and maximum oxygen consumption increased. Patients with chronic obstructive bronchitis, who passed the breathing rate of heated oxygen-helium mixture, had an increase in points on WBAM Questionnaire, which indicates the improvement of the psycho-emotional state of patients. CONCLUSION: The use of the course of breathing heated oxygen-helium mixture in patients with chronic obstructive bronchitis does not affect the increase in physical performance. The use of heated oxygen-helium mixture has a positive effect on the functional state of practically healthy patients, which is manifested in the form of slowing the connection of the anaerobic mechanisms of energy supply in the process of performing physical exertion, leading to an increase in oxygen consumption, improving physical performance.

Exercise Tolerance Breathing a Low Density Gas Mixture, 35% Oxygen and Air in Patients with Chronic Obstructive Bronchitis

1970 ◽  
Vol 39 (5) ◽  
pp. 675-685 ◽  
Author(s):  
A. C. Raimondi ◽  
R. H. T. Edwards ◽  
D. M. Denison ◽  
D. G. Leaver ◽  
R. G. Spencer ◽  
...  
Keyword(s):  
Constant Load ◽  
Gas Mixtures ◽  
Forced Expiratory Volume ◽  
Pulmonary Mechanics ◽  
Chronic Obstructive ◽  
Gas Mixture ◽  
Chronic Obstructive Bronchitis ◽  
Helium Mixture ◽  
Maximum Expiratory Flow ◽  
Expiratory Flow

1. We have examined the effects of (a) reducing the density of the inspired gas and of (b) increasing inspired oxygen concentration on the exercise performance of eight men with chronic obstructive bronchitis (COB). 2. Each subject performed two types of exercise test breathing three different gas mixtures: air, 35% oxygen in nitrogen and 21% oxygen in helium. The exercise capacity, ventilation and heart rate were recorded. Indices of pulmonary mechanics were measured to determine where and how any change in ventilatory capacity might have been achieved. 3. (a) Effort tolerance at a constant load (70% capacity breathing air) was greater when the inspired gas mixture was 35% oxygen in nitrogen than when air or 21% oxygen in helium was breathed. (b) Peak expiratory flow (PEF) was greater when the helium mixture was breathed, but the forced expiratory volume in 1 s (FEV1) and maximum expiratory flow at 50% vital capacity (MEF50%) were the same as when breathing air. Effort tolerance was the same breathing the helium mixture and air in both the progressive and constant load tests. (c) PEF, FEV and MEF50% were greater immediately after than before exercise on all gas mixtures. 4. It is concluded that a reduction in the density of the inspired gas does not improve effort tolerance in patients with COB. Possible reasons for this lack of benefit are discussed.

Combined use of theopek and corinphar in chronic obstructive bronchitis

1993 ◽  
Vol 74 (3) ◽  
pp. 191-192
Author(s):  
I. B. Amirov
Keyword(s):  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Ischemic Heart ◽  
Chronic Obstructive ◽  
External Respiration ◽  
Chronic Obstructive Bronchitis ◽  
Combined Use ◽  
Respiration Function

As many as 114 patients with chronic obstructive bronchitis combined with ischemic heart disease are examined. The combined use of theopek (300900 mg per day) and corinphar (3060 mg per day) significantly improves the external respiration function.

Dynamics of some immunological parameters during treatment with pentoxil in patients with chronic obstructive bronchitis

1985 ◽  
Vol 66 (4) ◽  
pp. 271-274
Author(s):  
F. V. Arsentiev ◽  
S. B. Marasanov
Keyword(s):  
Chronic Diseases ◽  
Immune Defense ◽  
Chronic Obstructive ◽  
Immunological Parameters ◽  
Chronic Obstructive Bronchitis

An important reason for the frequent recurrence and progression of chronic diseases is considered to be a violation of the body's immune defense [7, 9].

Possibilities of cardiovascular events in patients with chronic obstructive pulmonary disease and newly diagnosed tuberculosis, including those associated with HIV infection, when prescribing long-acting β2-agonists

MedAlliance ◽  
2020 ◽  
Vol 8 (2) ◽  
pp. 32-39
Keyword(s):  
Blood Pressure ◽  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Chronic Obstructive ◽  
Bronchial Obstruction ◽  
External Respiration ◽  
Obstructive Pulmonary Disease ◽  
Tb Treatment ◽  
Long Acting ◽  
Β2 Agonists

Chronic obstructive pulmonary disease (COPD) and pulmonary tuberculosis (TB) are a common pathology among respiratory diseases. Both conditions may have common risk factors, aggravating each other, accom-panied by the development of bronchial obstructive syndrome, requiring mandatory medical correction to increase the effectiveness of therapy for both the main and concomitant pathologies. The aim of the study was to study the effectiveness of treatment of TB in patients with COPD first diagnosed with tuberculosis, including those associated with HIV when prescribing long-acting β2-agonists. Materials and methods. A simple com-parative study included 60 patients of a TB dispensary aged 30–65 years. Patients were divided into 2 groups of 30 people (TB+COPD and TB+COPD+HIV), each of whom for 2 months received a long-acting β-agonist (indacaterol) as an accompanying therapy for the cor-rection of bronchial obstructive syndrome (BOS), with subsequent assessment of the effectiveness of therapy. Results. Subjectively, patients of both groups noted the rapid development of positive dynamics (short-ness of breath decreased from 1–3 days of taking the drug, coughing — within a week, tolerance to physical exertion improved), which was confirmed by indica-tors of the function of external respiration (FEV1). The state of the cardiovascular system was assessed by the results of daily monitoring of blood pressure (BPM). In the COPD+TB group, there is a certain average daily systolic blood pressure (SBP) with a tendency to nor-malize indicators, which is possibly associated with a decrease in the severity of hypoxia during bronchodi-lator therapy. In the COPD+TB+HIV group, the average daily level of SBP increased by 1 mm Hg, but given the very low starting rates, the increase in blood pressure had a positive effect on the patients' condition. The average heart rate (HR) during bronchodilator thera-py did not tend to increase. The best TB treatment re-sults were obtained in the TB+COPD group. In terms of the closure rate of TB+COPD decay cavities — 26.6%, TB+COPD+HIV — 20.0%), the TB+COPD+HIV group had longer periods of abacillation and closure of decay cav-ities, which is associa ted with the severity of the under-lying and associated diseases. The drug was well toler-ated in both groups. Conclusion. The use of 300 mcg long-acting β-adrenomimetics in the complex therapy of β2-adrenergic agonists for patients with TB+COPD and TB+ COPD+HIV can reduce the severity of bronchial obstruction syndrome, improve quality of life, increase adherence to TB treatment, thereby shortening hospi-talization and reduce the likelihood of disability of pa-tients, without the development of side effects from other organs and systems.

The state of the cardiovascular system in occupational bronchitis and chronic obstructive pulmonary disease, not associated with the impact of harmful industrial factors

2021 ◽  
pp. 55-68
Author(s):  
Vyacheslav S. Lotkov ◽  
Anton Vladimirovich Glazistov ◽  
Antonina G. Baykova ◽  
Marina Yuryevna Vostroknutova ◽  
Natalia E. Lavrentieva
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Cardiovascular System ◽  
Pulmonary Disease ◽  
Lung Diseases ◽  
Chronic Obstructive ◽  
External Respiration ◽  
Obstructive Pulmonary Disease ◽  
Occupational Lung Diseases ◽  
The Right ◽  
The Impact

The formation and progression of chronic dust bronchitis and chronic bronchitis of toxic-chemical etiology, chronic obstructive pulmonary disease is accompanied by an increase in the degree of ventilation disorders, echocardiographic signs of hypertrophy and dilatation of the right ventricle are formed, typical for chronic pulmonary heart disease. The progression of disturbances in the function of external respiration in dusty lung diseases leads to a decrease in myocardial contractility. The detection of hemodynamic disturbances at the early stages of the development of occupational lung diseases indicates the need for individual monitoring of the functional state of the cardiovascular system in the process of contact with industrial aerosols, especially in groups of workers with long-term exposure.

CHRONIC OBSTRUCTIVE PULMONARY DISEASE AND COMORBIDITIES: MANAGEMENT OF SOMATOFORM DISORDERS

2021 ◽  
Vol 74 (6) ◽  
pp. 1401-1404
Author(s):  
Liliia V. Burya ◽  
Anna A. Kapustianska ◽  
Nataliia V. Moiseieva ◽  
Andrii V. Vakhnenko ◽  
Mariia O. Rumiantseva ◽  
...  
Keyword(s):  
Oxygen Saturation ◽  
Somatoform Disorders ◽  
Comprehensive Evaluation ◽  
Pulmonary Ventilation ◽  
Multidisciplinary Care ◽  
Step Test ◽  
Chronic Obstructive ◽  
Copd Exacerbations ◽  
Group D ◽  
Severe Copd

The aim: To perform a comprehensive evaluation of the effect of paroxetine on the degree of somatoform disorders in exacerbation of severe COPD in women. Materials and methods: The study involved 53 female patients with severe COPD (Group D), confirmed by instrumental methods of study. At hospitalization, patients were divided into 2 groups. Patients of Group 1 (n = 21; aged 52.5 ± 0.8 years old) underwent basic exacerbation therapy. Patients of Group 2 (n = 22; aged 57.9 ± 0.4 years old) underwent basic exacerbation therapy supplemented with paroxetine for 14 days, 1 tablet (0.20 g) once a day. Results: The basic therapy for treatment of COPD exacerbations, supplemented with paroxetine, led to a positive clinical effect, confirmed by increase in skeletal and respiratory muscular system, increased parameters of pulmonary ventilation, increased tolerance to physical load, increased oxygen saturation, decreased heart rate and breathing rate. Conclusions: The strategy for choosing an antidepressant to provide multidisciplinary care for somatoform disorders in women with exacerbation of severe COPD (group D) should take into account the efficacy and favorable safety profile and personalization of the drug. In exacerbation of severe COPD, the degree of somatoform disorders in patients correlates with the severity of the main criteria: FVC1, the distance walked during the 6-minute step test, oxygen saturation after the 6-minute step test, end-expiratory pressure in the oral cavity.

scholarly journals Features of medical rehabilitation of patients who have suffered an ischemic stroke and have a history of obstructive chronic disorders of the respiratory system without exacerbation.

2021 ◽  
Vol 19 (5) ◽  
pp. 299-304
Author(s):  
Svetlana N. Vygovskaya ◽  
Alexey A. Voropaev ◽  
Tatyana V. Konchugova ◽  
Elena M. Styazhkina
Keyword(s):  
Ischemic Stroke ◽  
Respiratory System ◽  
Cerebral Circulation ◽  
Recovery Period ◽  
Medical Rehabilitation ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Standard Drug ◽  
Rehabilitation Programs ◽  
Late Recovery

Background. To date, the study of respiratory function in the clinic is limited, as a rule, to the determination of bronchial conduction indicators, as well as bronchodilation tests, which at the present stage is insufficient for a deep assessment of the functional state of patients with chronic obstructive pulmonary disease. Aims. The development of personalized medical rehabilitation programs for patients who have undergone ischemic stroke at various stages of rehabilitation, including spa. Materials and methods. The article considers the effectiveness of the new method of treating neurological disorders in patients suffering from acute cerebral circulation disorder and having respiratory system function disorder at different stages of rehabilitation, based on the complex application of physiobalneotherapy, LFC and mechanotherapy in sanatorium and resort conditions. Results. After the course of using physical methods of treatment, patients with comorbid pathology showed improvement in health, relief of breathing, reduction of shortness of breath, cough, sputum production, disappearance of wheezing in the lungs. Conclusion. Patients in the early and late recovery period after acute cerebral circulation disorder with accompanying clinical-functional manifestations of respiratory pathology are shown to include in the rehabilitation complex general gasair carbon dioxide baths, nebulizer inhalations of broncho- and mucolytic preparations, as well as classes on a rowing simulator (rowing) against the background of standard drug therapy and therapeutic exercise in the hall.

scholarly journals Influence of the phenotype of the disease on the parameters of the antioxidant defense system and the level of some interleukins in the blood of patients with chronic obstructive pulmonary disease

2017 ◽  
Vol 8 (6) ◽  
pp. 38-41 ◽  
Author(s):  
Ivan I. Pavlyuchenko ◽  
Evgenii A. Kokov ◽  
Lyudmila N. Kokova ◽  
Olga S. Okhremenko
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Adaptive Systems ◽  
Complex Disease ◽  
Antioxidant Properties ◽  
The Body ◽  
Chronic Obstructive ◽  
Common Disease ◽  
Obstructive Pulmonary Disease ◽  
Active Forms Of Oxygen

Chronic obstructive pulmonary disease (COPD) is a common disease involving the pathological process, of bronchopulmonary and cardiovascular systems. This is a complex disease in which inflammation plays a leading role in the formation of the whole complex of pathological changes. COPD accompanies local deficit of antiproteases, excessive formation of active forms of oxygen, inducing uncontrolled lipid peroxidation and oxidative stress. An increase in the level of proinflammatory cytokines, such as IL-6, IL-8, TNF-α, is particularly significant in the combination of chronic obstructive disease with metabolic syndrome. Determination of a specific phenotype of COPD, and the degree of disruption of protective and adaptive systems in these forms of the disease course allows optimizing the treatment regimens for patients. The purpose of this work was to identify additional biochemical and biophysical markers of phenotyping and monitoring of therapy in patients with COPD of different phenotype and severity level in the acute stage on the basis of studying the main indicators of the system of antioxidant protection of blood and some cytokines. Significant differences in antioxidant system (AOS) indices in patients with COPD of different phenotype and severity were determined. The established differences in the activity of erythrocyte enzymes and the overall antioxidant activity of blood plasma can serve as an important additional link for the phenotyping of COPD. Complex treatment with the use of anticoagulants, normalizing the rheological properties of blood and mucolytics with pronounced antioxidant properties, reduces the level of prooxidant load on the body due to correction of metabolic processes and has the most pronounced effect on AOS blood parameters and cytokine profile.

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