The contents of neurospecific enolase and neurotrofic growth factor in the cord blood of healthy full-term newborns elective planned caesarean section surgery and spontaneous delivery

2015 ◽  
Vol 64 (6) ◽  
pp. 38-42
Author(s):  
Antonina Yurievna Morozova ◽  
Yuliya Pavlovna Milyutina ◽  
Aleksandr Vartanovich Arutyunyan ◽  
Inna Ivanovna Evsyukova
Keyword(s):  
Growth Factor ◽  
Caesarean Section ◽  
Blood Serum ◽  
Neuron Specific Enolase ◽  
Full Term ◽  
Umbilical Blood ◽  
Umbilical Blood Serum ◽  
Term Newborns ◽  
Low Levels ◽  
Spontaneous Delivery

The contents of neuron-specific enolase (NSE) and brain-derived neurotrophic factor (BDNF) was studied in the umbilical blood serum of healthy full-term newborns elective planned caesarean section and spontaneous delivery. The study has established that their levels in umbilical blood serum after elective planned caesarean section surgery are lover, than after spontaneous delivery. The authors of the article discuss the causes and possible effects of low levels of BDNF of newborns extrected elective planned caesarean section surgery before 39 weeks.

LEVELS AND DISTRIBUTION OF FREE AND C4b-BP-B0UND-PR0TEIN S IN HUMAN FETUSES AND FULL-TERM NEWBORNS

1987 ◽  
Author(s):  
P MOALIC ◽  
Y GRUEL ◽  
P FOLOPPE ◽  
B DELAHOUSSE ◽  
G BODY ◽  
...  
Keyword(s):  
Umbilical Vein ◽  
Protein S ◽  
Full Term ◽  
Free Form ◽  
Reference Curve ◽  
Direct Puncture ◽  
A Value ◽  
Term Newborns ◽  
Low Levels ◽  
Normal Adults

Levels and plasmatic distribution of protein S were studied on umbilical cordplasmas from 25 normal full-term newborns (N) and 15 normal fetuses (F) between20 and 30 weeks of gestation. Samples from fetuses were collected for antenatal diagnosis by direct puncture of the umbilical vein under high resolution real-time ultrasound. Total protein S(PS) level was determined using Laurell rocket immuno-electrophoresis (Diagnostica Stago, Asnifcres-France). Free PS wasmeasured using this latter method, afterprecipitation of C4b-BP-bound-PS by polyethylene glycol (PEG). Normal pool plasma, treated as well, was considered as the reference curve. C4b-binding protein (C4b-BP) determinations were conducted by Laurell rocket immunoelectrophoresis. The qualitative distribution of free PS and C4b-BP-bound-PS in plasma was also assessed by crossed-immunoelectrophoresis(CIE). Results (mean - SD) were expressed in percentage, in relation to healthy adults values (n = 15). Low levels of total PS were obtained in all fetuses (16.4 ±4.2) and newborns (36.4 ±9.5) as compared to adults (91.6 ± 12.2). Free protein S level was also decreased both in fetuses (22.2 ±6.0) and newborns (48.5 ± 12.1 versus 89.4 ± 26.3 in adults). At these stages of development, the ratio Free PS / Total PS (both values were obtained according to a reference curve performed with a normal adult pool plasma untreated by PEG) was significantly higher as compared to normal adults (0.82 ±0.07 in F, 0.64 ±0.17 in N and 0.39 ±0.11 in A, p‹0.001, Student t test). The predominance of free PS was also visualized in the CIE patterns. These data may be explained by undetectable C4b-BP in 21-week old fetuses (‹2% in 10 cases). After the 26th week of gestation C4b-BP level was 7.8 ±7.4 ‹n=5) and reached a value of 19.2 ±15.6 in newborns (adults = 95.7 ±14.7). In human fetus and newborn, PS essentially circulates under free form and this might compensate the decrease of the total PS level.

Organochlorine Pesticide Gradient Levels Among Maternal Adipose Tissue, Maternal Blood Serum and Umbilical Blood Serum

2011 ◽  
Vol 86 (3) ◽  
pp. 289-293 ◽  
Author(s):  
Margarita Herrero-Mercado ◽  
S. M. Waliszewski ◽  
M. Caba ◽  
C. Martínez-Valenzuela ◽  
S. Gómez Arroyo ◽  
...  
Keyword(s):  
Adipose Tissue ◽  
Blood Serum ◽  
Organochlorine Pesticide ◽  
Maternal Blood ◽  
Umbilical Blood ◽  
Umbilical Blood Serum

scholarly journals Maternal risk factors in full-term newborns with early onset sepsis related with Interleukin-6 in umbilical blood

2019 ◽  
Vol 19 (2) ◽  
Author(s):  
Fabricio González Andrade
Keyword(s):  
Risk Factors ◽  
Urinary Tract ◽  
Gestational Age ◽  
Interleukin 6 ◽  
Neonatal Sepsis ◽  
Full Term ◽  
Maternal Risk ◽  
Umbilical Blood ◽  
Term Newborns ◽  
Relationship Of

Background: to determine the relationship and association of early sepsis with interleukin-6 measured in umbilical blood, as well as gestational age and birth weight, prenatal history of the mother pathologies during pregnancy, in full-term newborns at the Neonatology Service of Carlos Andrade Marín Hospital (Quito). Subjects and methods: epidemiological, observational, analytical, cross-sectional. 200 newborns were analyzed. IL-6 was determined by Elisa. Results: newborn mean gestational age 38.4±2 weeks, mean weight 2871±532.4 grams,  cutoff point interleukin 6 ≤14pg/uL; mean of IL6. 58±99,1 pg/uL; male sex was 43.9%, female sex 56.1%; preeclampsia of the mother 22.4%, prenatal infection of the urinary tract 20.4%; vaginitis/vaginosis 19.4%; IL6 values ≤ 14 pg/uL in 63.3% of patients; IL6 values of >14 pg/uL 36.7%; relationship with sepsis in all, p<0.05; relationship of prenatal pre-maternity of the mother and neonatal sepsis. p<0.05; relationship between vaginitis/vaginosis of the mother with neonatal sepsis; p<0.05; OR: 38.88 IC95% (4.912-307.728); association between sepsis and risk factors, IL6, gestational age in weeks, weight, prenatal preeclampsia, prenatal urinary tract infection, vaginitis/vaginosis, p<0.05. Conclusion: It is concluded that there is a relationship of risk factors, such as, gestational age in weeks, weight, prenatal preeclampsia, prenatal UTI, vaginitis/vaginosis and values of interleukin 6 ≤ 14 pg/uL. The mean gestational age was 38.4 weeks, and average weight 2871 grams in the newborns analyzed.

scholarly journals BIOCHEMICAL MARKERS OF RENAL DYSFUNCTIONS IN CRITICALLY ILL FULL - TERM NEWBORNS

2015 ◽  
pp. 15-20
Author(s):  
A. Babintseva
Keyword(s):  
Blood Serum ◽  
Critically Ill ◽  
Immunoglobulin G ◽  
Intensive Therapy ◽  
Clinical Signs ◽  
Main Group ◽  
Full Term ◽  
Control Group ◽  
Perinatal Pathology ◽  
Term Newborns

Introduction. Full - term newborns with clinical signs of severe perinatal pathology constitute a high risk group of the formation of urinary system functional disorders, the diagnostic of which in the early neonatal period is complicated. Objective of the research was to study the condition of renal functions in critically ill full - term newborns during the first week of their life by means of detection of specific biomarkers level in the blood serum and urine. Materials and methods. A comprehensive clinical - paraclinical examination of 36 critically ill newborns (the main group) and 37 conditionally healthy newborns (the control group) has been conducted. Laboratory methods ofexamination included detection of the levels of creatinine, urea, sodium and potassium ions in the blood and urine, as well as protein, albumin, immunoglobulin G, a - - microglobulinand $ - microglobulinin urine. Results and discussion. The neonates of the main group as compared to the control one presented statistically significant higher levels of creatinine (р<0,01) and urea (р<0,001) in the blood serum against the ground of lower glomerular filtration rate (р<0,05) and the level ofpotassium ions (р<0,01); in the urine — statistically significant lower level of creatinine (р<0,01), higher levels of urea (р<0,001) and sodium ions (р<0,05). Evaluation of urineproteinogramin the main group of newborns as compared to the control group enabled to find statistically significant higher levels of protein (р<0,01), albumin (р<0,01), immunoglobulin G (р<0,05), a - - microglobulin (р<0,01), $ - - microglobulin (р<0,01). Conclusions. Critically ill full - term newborns with perinatal pathology receiving treatment in the Intensive Care Unit are under conditions of a complex influence of potentially nephrotoxic factors (hypoxia, reoxygenation - reperfusion, infection, artificial lung ventilation, infusion, inotropic, transfusion and antibacterial therapy). Severity of general condition, morpho - functional immaturity of the organism, multiple organ failure due to underlying perinatal pathology “obscure” renal symptoms and complicate the diagnostics of renal function disorders. The biochemical changes found in critically ill newborns require timely diagnostics to correct therapeutic measures on the stage of intensive therapy with the aim to prevent the development of severe renal pathology and chronic renal failure in future.

Partitioning Coefficients of Organochlorine Pesticides Between Mother Blood Serum and Umbilical Blood Serum

2000 ◽  
Vol 65 (3) ◽  
pp. 293-299 ◽  
Author(s):  
S. M. Waliszewski ◽  
A. A. Aguirre ◽  
R. M. Infanzon ◽  
J. Siliceo
Keyword(s):  
Blood Serum ◽  
Organochlorine Pesticides ◽  
Umbilical Blood ◽  
Umbilical Blood Serum ◽  
Partitioning Coefficients

Partitioning Coefficients of Organochlorine Pesticides Between Mother Blood Serum and Umbilical Blood Serum

2000 ◽  
Vol 65 (3) ◽  
pp. 293-299 ◽  
Author(s):  
S. M. Waliszewski ◽  
A. A. Aguirre ◽  
R. M. Infanzon ◽  
J. Siliceo
Keyword(s):  
Blood Serum ◽  
Organochlorine Pesticides ◽  
Umbilical Blood ◽  
Umbilical Blood Serum ◽  
Partitioning Coefficients

Association of Cord Blood Leptin, Soluble Leptin Receptor, Insulin-Like Growth Factor-I and Insulin-Like Growth Factor-Binding Protein-1 on Birth Indices in Healthy Full-Term Newborns

2014 ◽  
Vol 81 (4) ◽  
pp. 232-238 ◽  
Author(s):  
Kamani H. Tennekoon ◽  
Jayanthiny Poopalapillai ◽  
Akila G. Karunanayake ◽  
Hasini D. Jayasinghe ◽  
Jayalath M. Kumarasiri ◽  
...  
Keyword(s):  
Growth Factor ◽  
Cord Blood ◽  
Leptin Receptor ◽  
Binding Protein ◽  
Full Term ◽  
Insulin Like Growth Factor ◽  
Factor Binding ◽  
Factor I ◽  
Soluble Leptin Receptor ◽  
Term Newborns

EFFECT OF BALA TAILA MATRA BASTI AND YONIPICHU IN ACHIEVING SUKHAPRASAVA (NORMAL LABOUR) - A CASE STUDY.

2021 ◽  
pp. 20-22
Author(s):  
Veena Jawale ◽  
Sonam R. Patil
Keyword(s):  
Caesarean Section ◽  
Female Child ◽  
Full Term ◽  
Theoretical Research ◽  
Normal Delivery ◽  
Vertex Presentation ◽  
Spontaneous Delivery

Ayurveda is an indigenous system of medicine, emphasizing the Garbhavakranti (process of development of various components in Embryo) to prasavaprocess of normal labour) & Sutika (puerperium) very well. Nowadays due to changing lifestyle and daily habbits most of the women tend to go for caesarean section. Which has its own remote complications. Normal delivery is not only safe for mother but also for the baby. In Garbhini Paricharya Acharyas have mentioned Basti and yoni pichu moreover with Madhura aushadi siddha taila to facilitate sukhaprasava (eutocia). Aim- To study Bala taila Matra basti & Yonipichu in Sukhaprasava. Methodology- Use of Bala taila Matra basti & Yonipichu in Prakruta Garbhini for Sukhaprasava based on theoretical research using texts of Ayurveda. Result-A full-term spontaneous delivery (sukhaprasava) of a primi patient with vertex presentation of live female child of weight 3.2 kg on 15th February 2021 at 3.20pm.

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