Clinical aspects of the use of recombinant interferon preparations

1993 ◽  
Vol 74 (1) ◽  
pp. 1-4
Author(s):  
O. I. Pikuza ◽  
I. Yu. Blinnikov
Keyword(s):  
Clinical Aspects ◽  
Recombinant Interferon ◽  
Prevention And Treatment ◽  
Highly Effective ◽  
Oncological Diseases ◽  
Immunomodulatory Properties ◽  
The Creation

One of the modern trends in the prevention and treatment of viral, immunodeficient and oncological diseases is the use of drugs of the interferon group (IF). This is facilitated by the creation of a number of new highly effective recombinant IFs exhibiting not only antiviral, but also pronounced antiproliferative and immunomodulatory properties.

scholarly journals Clinical Aspects of Gastric Cancer and Helicobacter pylori- Screening, Prevention, and Treatment

Helicobacter ◽  
2010 ◽  
Vol 15 ◽  
pp. 40-45 ◽  
Author(s):  
Michael Selgrad ◽  
Jan Bornschein ◽  
Theodore Rokkas ◽  
Peter Malfertheiner
Keyword(s):  
Gastric Cancer ◽  
Helicobacter Pylori ◽  
Clinical Aspects ◽  
Prevention And Treatment

scholarly journals Artemisia annua, a Traditional Plant Brought to Light

2020 ◽  
Vol 21 (14) ◽  
pp. 4986 ◽  
Author(s):  
Axelle Septembre-Malaterre ◽  
Mahary Lalarizo Rakoto ◽  
Claude Marodon ◽  
Yosra Bedoui ◽  
Jessica Nakab ◽  
...  
Keyword(s):  
Developing Countries ◽  
Phenolic Compounds ◽  
Artemisia Annua ◽  
State Of The Art ◽  
Biological Activities ◽  
Biological Properties ◽  
Chemical Components ◽  
Traditional Remedies ◽  
Prevention And Treatment ◽  
Immunomodulatory Properties

Traditional remedies have been used for thousand years for the prevention and treatment of infectious diseases, particularly in developing countries. Of growing interest, the plant Artemisia annua, known for its malarial properties, has been studied for its numerous biological activities including metabolic, anti-tumor, anti-microbial and immunomodulatory properties. Artemisia annua is very rich in secondary metabolites such as monoterpenes, sesquiterpenes and phenolic compounds, of which the biological properties have been extensively studied. The purpose of this review is to gather and describe the data concerning the main chemical components produced by Artemisia annua and to describe the state of the art about the biological activities reported for this plant and its compounds beyond malaria.

Metatypical basal cell carcinoma in young man

2016 ◽  
Vol 19 (3) ◽  
pp. 132-136
Author(s):  
Elena S. Snarskaya ◽  
L. R Plieva ◽  
I. S Maximov
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Historical Data ◽  
Distant Metastases ◽  
Skin Tumors ◽  
Recombinant Interferon ◽  
Clinical Investigations ◽  
Frequent Relapses ◽  
Oncological Diseases

Malignant epithelial skin tumors are leading among oncological diseases worldwide. In most cases epithelial skin tumors affect areas, susceptible to the action of adverse environmental factors. Metatypical basal cell carcinoma is a variant of basal cell carcinoma that combines the features of basal cell and squamous cell carcinomas. It characterized by infiltrative growth and the destruction of the underlying tissues, pain, bleeding, formation of distant metastases and frequent relapses. Metatypical basal cell carcinoma is more common in women, with the average age is 70.5 years. Historical data, the results of own clinical investigations, rare case of metatypical basal cell carcinoma of the young man, who was successfully treated with recombinant interferon-a2 and prospidinum are presented.

Prevention and treatment of secondary brain damage. Clinical aspects

CHEST Journal ◽  
1991 ◽  
Vol 100 (3) ◽  
pp. 200S-202
Author(s):  
A. Unterberg ◽  
A. Baethmann ◽  
W. Lanksch
Keyword(s):  
Brain Damage ◽  
Clinical Aspects ◽  
Secondary Brain Damage ◽  
Prevention And Treatment

scholarly journals RABBIT BIOMODELS OF HUMAN DISEASES DEVELOPED USING NEW GENOMIC TECHNOLOGIES. CRISPR/CAS9 (REVIEW)

Biomeditsina ◽  
2019 ◽  
pp. 12-33
Author(s):  
E. M. Koloskova ◽  
V. N. Karkischenko ◽  
V. A. Yezersky ◽  
N. V. Petrova ◽  
S. V. Maksimenko ◽  
...  
Keyword(s):  
Genome Editing ◽  
Human Disease ◽  
Genetically Modified ◽  
Human Diseases ◽  
Present Review ◽  
Disease Models ◽  
Genomic Technologies ◽  
Highly Effective ◽  
The Creation

With the advent of endonuclease methods of genome editing, particularly CRISPR/Cas9, it has become possible to obtain genetically modified rabbits by microinjection of zygotes. These highly effective human disease models can be used for various purposes. The present review aims to consider modern achievements in the creation of rabbit biomodels of human diseases using the technologies of genetic editing. It is concluded that Russian laboratories should intensify research in the development of genetically modified rabbits that can be used for various biomedical studies and biomodelling.

scholarly journals The benefits of ascorbate to protect healthy cells in the prevention and treatment of oncological diseases

2020 ◽  
Vol 18 (1) ◽  
pp. 1-7
Author(s):  
Pavel Klener ◽  
Matthew Scott Alexander ◽  
Joseph John Cullen ◽  
Věra Stejskal ◽  
Jiří Slíva ◽  
...  
Keyword(s):  
Prevention And Treatment ◽  
Oncological Diseases

Cervical cancer in the Russian Federation and the risks of vaginal fistula

2021 ◽  
Vol 11 (2) ◽  
pp. 49-54
Author(s):  
M. N. Saryev ◽  
R. K. Valiev ◽  
M. I. Nechushkin ◽  
M. B. Nurberdyev ◽  
I. V. Panichenko ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Russian Federation ◽  
Vaginal Fistula ◽  
Factors Associated ◽  
Increased Risk ◽  
Relevant Task ◽  
Prevention And Treatment ◽  
Oncological Diseases ◽  
The Russian Federation

This review aims to provide up-to-date information on the factors associated with an increased risk of vaginal fistula in women with cervical cancer, as well as on methods of their prevention and treatment. It includes data on various types of vaginal fistulas in cervical cancer patients and risk factors for their development, according to foreign and Russian research articles published over the last 20 years. Cervical cancer is one of the most challenging oncological diseases in the Russian Federation, because it is detected at stage III–IV in more than 30 % of women. Such a high incidence of cervical cancer and the need for radiotherapy determine high risk of fistulas, which significantly impairs the quality of life. Thus, identification of factors associated with vaginal fistulas, as well as methods of their prevention and treatment remains a highly relevant task for the Russian healthcare system.

AMNIOTIC MEMBRANE-AS AN EFFECTIVE BIOLOGICAL WOUND COVERING

2021 ◽  
Vol Special issue (1) ◽  
pp. 31-36
Author(s):  
Yokubjon Hursanov ◽  
◽  
Ishnazar Mustafakulov ◽  
Xudoyberdi Karabaev ◽  
Zilola Djuraeva ◽  
...  
Keyword(s):  
Wound Healing ◽  
Water Vapor ◽  
Amniotic Membrane ◽  
Absorption Capacity ◽  
Burn Treatment ◽  
Traumatic Injuries ◽  
Wound Exudate ◽  
Highly Effective ◽  
The Creation ◽  
High Absorption

Burns are one of the most widespread traumatic injuries. The number of victims of burns worldwide is steadily increasing. All this determines the search for new highly effective methods of treating burned patients. (1.2.4.5.20.)The main requirements for wound healing are the creation of an optimal microenvironment for wound healing, high absorption capacity for wound exudate, the ability to prevent the ingress of microorganisms, sufficient permeability to gases, water vapor, elasticity, pyrogenicity, lack of antigen, toxic, local irritants and allergic reactions.Keywords:obligate component, amniotic membrane, hematocrit value, burn treatment, amnion

The molecular and genetic basis of carcinogenesis

2019 ◽  
Author(s):  
Аскольд Майборода ◽  
Aleksei Kaliagin
Keyword(s):  
Genetic Basis ◽  
Diagnostic Techniques ◽  
Federal State ◽  
Clinical Aspects ◽  
Tumor Type ◽  
Cellular Events ◽  
Oncological Diseases ◽  
State Educational

The textbook deals with the classification of tumor growth, signs of malignancy, genetic basis of cancer, chronology of cellular events of oncogenesis. The differences between oncogenes and suppressor genes by the principle of action, the role of apoptosis in the processes of programmed cell death and their utilization are discussed. Attention is paid to the role of apoptosis defects in the development of oncogenic States. The modern ideas about the diagnosis of oncological diseases, which include screening examinations and individual verification of the tumor type, are generalized. The modern successes of diagnostic techniques, which were the result of the combined capabilities of molecular genetics and cytogenetics, are noted. The features of the course of virus-induced and non-viral forms of cancer are analyzed. Fundamental and clinical aspects of Oncology are combined. Meets the requirements of the Federal state educational standards of higher education of the last generation. For students on programs of specialization "Medical business", "Pediatrics", "Medical biochemistry". It will also be useful for residents and doctors.

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