State of antioxidant mechanisms in ischemic insults

1999 ◽  
Vol 80 (5) ◽  
pp. 371-373
Author(s):  
L. I. Reikhert
Keyword(s):  
Cerebrospinal Fluid ◽  
Blood Plasma ◽  
Antioxidant Defense ◽  
Clinical Manifestations ◽  
Antioxidant Defense System ◽  
Defense System ◽  
Ischemic Insult ◽  
Antioxidant Mechanisms ◽  
In Blood Plasma

The activity of superoxidismutase and catalase in thrombocytes as well as content of -tocopherol and -carotin in blood plasma and cerebrospinal fluid in 193 patients with ischemic insult are studied. Incompetence of the mechanisms of antioxidant defense correlating with gravity and outcome of ischemic insult is established. Depression of various links of the antioxidant defense system in blood plasma, thrombocytes and cerebrospinal fluid affects the gravity of clinical manifestations of the disease.

MORPHOLOGICAL INDICATORS OF BLOOD, RESISTANCE OF THE ORGANISM AND MEAT PRODUCTIVITY OF PIGLET AT APPLICATION OF 20-HYDROXYEXDISONE

2020 ◽  
Vol 1 (3) ◽  
pp. 371-377
Author(s):  
A.G. Solovieva ◽  
◽  
K.T. Erimbetov ◽  
O.V. Obvintseva ◽  
◽  
...  
Keyword(s):  
Blood Plasma ◽  
Antioxidant Defense ◽  
Antioxidant Defense System ◽  
The Body ◽  
Natural Resistance ◽  
Defense System ◽  
Growing Period ◽  
Meat Productivity ◽  
Experimental Group ◽  
In Blood Plasma

The effectiveness of using 20-hydroxyecdysone in the diet of piglets during the growing period and its effect on the formation of natural resistance, the antioxidant defense system of the body and their meat productivity were studied. The introduction of 20-hydroxyecdysone into the diet at the rate of 30 mg per kg of feed positively influenced on the bactericidal and lysozyme activity of blood serum, which in the experimental group were higher by 12,9 and 14,0%, respectively, compared with the control. The activity of superoxide dismutase and catalase enzymes in blood plasma in piglets of the experimental group was statistically significantly higher compared to the control. On the contrary, the content of malondialdehyde in blood plasma was statistically significantly lower in piglets of the experimental group compared with the control (17,1%, P≤0,01). In piglets of the experimental group, in comparison with the control, the output of muscle tissue (by 5,3%, P≤0,01), the area of the “muscle eye” (34,5%, P≤0,05) was statistically significantly higher, with less adipose tissue outlet.

scholarly journals Peroxidative degradation of proteins and lipids in undifferentiated connective tissue dysplasia in children, Ukraine

Narra J ◽  
2021 ◽  
Vol 1 (2) ◽  
Author(s):  
Tetyana V. Pochynok ◽  
Maryna M. Vasiukova ◽  
Iryna S. Kudlatska-Tyshko
Keyword(s):  
Lipid Peroxidation ◽  
Connective Tissue ◽  
Blood Plasma ◽  
Antioxidant Defense ◽  
Venous Blood ◽  
Colorimetric Method ◽  
Antioxidant Defense System ◽  
Defense System ◽  
Protein Peroxidation ◽  
Connective Tissue Dysplasia

The aim of the study was to assess the state of lipid and protein peroxidation in children with undifferentiated connective tissue dysplasia (UCTD). In this study, 63 children (33 children with UCTD and 30 children without UCTD were recruited and the indicators of lipid and protein peroxidation were measured. The enzymatic, colorimetric method was used to measure the level of total cholesterol (TC). The phospholipids were analyzed by liquid chromatography/mass spectrometry using electrospray ionization. Lipid peroxidation was studied by assessing the change of index and the end product of lipid peroxidation, malondialdehyde (MDA), using spectrophotometric method. Protein peroxidation - by the content of carbonylated protein based on 2,4 dinitrophenyl-hydrazones derivatization. The activity of the antioxidant defense system enzymes was assessed by measuring catalase (CAT) and superoxide dismutase (SOD). Our study revealed a significant increase of PPO products in the venous blood plasma and LPO products in erythrocytes in children with UCTD. Furthermore, an imbalance of the antioxidant defense system was observed in both blood plasma and erythrocytes membrane.

Pathogenetic Therapy of Patients with Recurrent Genital Herpes

2020 ◽  
Vol 65 (5-6) ◽  
pp. 30-34
Author(s):  
L. L. Logvina ◽  
D. N. Bayram ◽  
Z. A. Kambachokova ◽  
F. V. Shavaeva ◽  
Z. S. Krymshokalova ◽  
...  
Keyword(s):  
Lipid Peroxidation ◽  
Blood Plasma ◽  
Genital Herpes ◽  
Antioxidant Defense ◽  
Clinical Manifestations ◽  
Complex Treatment ◽  
Herpesvirus Infection ◽  
Recurrent Genital Herpes ◽  
Complex Therapy ◽  
Pathogenetic Therapy

Evaluation of the effectiveness of aminophthalhydroside in the complex treatment of patients with recurrent genital herpes was carried out. The efficacy of the drug was assessed by clinical, biochemical, and immunological criteria. The inclusion of aminophthalhydrazide in the complex therapy of patients with recurrent herpesvirus infection led to an earlier relief of clinical manifestations of the disease, an increase in the relapse period, a decrease in lipid peroxidation products in the blood plasma, an increase in the content of antioxidant defense components, and correction of immunological disorders.

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