scholarly journals The status of element homeostasis in children and adolescents with essential arterial hypertension

2012 ◽  
Vol 93 (2) ◽  
pp. 184-190
Author(s):  
T P Makarova ◽  
Z R Khabibrakhmanova ◽  
D I Sadykova ◽  
Yu M Chilikina
Keyword(s):  
Blood Pressure ◽  
Arterial Hypertension ◽  
Blood Serum ◽  
Children And Adolescents ◽  
Arterial Blood Pressure ◽  
Childhood And Adolescence ◽  
Functional Variants ◽  
Arterial Blood ◽  
Essential Arterial Hypertension ◽  
Metabolic Type

Aim. To study the features of element homeostasis in children and adolescents with different variants of essential arterial hypertension. Methods. The clinical and functional variant of arterial hypertension was established based on the data of 24-hour monitoring of the arterial blood pressure. Investigation of the element content in the blood serum and daily urine was performed using the method of atomic absorption spectrophotometry. The clearance and the excreted fraction of the investigated elements were measured. Results. Revealed was an increase of the content of lead in the blood serum, an increase in lead excretion with urine, an increase in its clearance and excreted fraction in patients with stable arterial hypertension. It has been shown that for children and adolescents with a variety of clinical and functional variants of arterial hypertension characteristic is an excess of the serum content of a toxic element (lead) over the content of an essential element (zinc), and these changes are most pronounced in the group with stable arterial hypertension. In children and adolescents with the increase in arterial blood pressure registered was a decrease in the content of zinc and magnesium in the blood serum, whereas the disturbances of element homeostasis relate to the metabolic type. The increase in the content of copper and calcium in blood serum of patients with high blood pressure is also a manifestation of the metabolic type of element homeostasis disturbances. Conclusion. The increased level of lead in blood serum in combination with its enhanced excretion may be a cofactor in the development of essential arterial hypertension in childhood and adolescence.

scholarly journals Metabolism of quantity elements and essential trace elements in patients with essential arterial hypertension in different ecological settings

2013 ◽  
Vol 94 (6) ◽  
pp. 798-803 ◽  
Author(s):  
Z R Khabibrakhmanova ◽  
T P Makarova ◽  
D I Sadykova
Keyword(s):  
Blood Pressure ◽  
Arterial Hypertension ◽  
Children And Adolescents ◽  
Blood Pressure Monitoring ◽  
Essential Elements ◽  
Healthy Children ◽  
Residential Areas ◽  
Pressure Monitoring ◽  
Industrial Areas ◽  
Essential Arterial Hypertension

Aim. To study the specifics of lead, zinc, copper, magnesium and calcium metabolism in children and adolescents with essential arterial hypertension living in different ecological settings. Methods. 100 children and adolescents aged 13-17 years with arterial hypertension, living in «industrial» (52 patients) and «residential» (48 patients) areas were examined in cardiology ward. 33 healthy children and adolescents comparable by age and gender were included as healthy controls. According to 24-hour blood pressure monitoring, groups with stable, labile arterial hypertension and «white coat hypertension» were formed. The levels of elements in 24-hour urine and in serum were measured by atomic absorption spectrophotometry. Results. In children and adolescents with stable arterial hypertension living in industrial areas, parameters of 24-hour blood pressure monitoring (mean 24-hour and mean daytime systolic blood pressure values, time of systolic hypertension, mean 24-hour and mean daytime blood pressure values) were higher compared to the same parameters in children from residential areas, the difference was statistically significant. The study of elements metabolism revealed increased lead exposure in children with essential arterial hypertension living in industrial areas, and misbalance of essential elements in those patients compared to the same parameters in children from residential areas. Conclusion. Results suggest increased exposure to arterial hypertension and marked misbalance of essential elements in children and adolescents with essential arterial hypertension living in industrial areas.

Body Mass Index and Cardiovascular Risk Factors in Children and Adolescents with High Birth Weight

2018 ◽  
Vol 72 (4) ◽  
pp. 272-278 ◽  
Author(s):  
Daniel L. Ledo ◽  
Fabíola Isabel Suano-Souza ◽  
Maria do Carmo P. Franco ◽  
Maria Wany L. Strufaldi
Keyword(s):  
Risk Factors ◽  
Insulin Resistance ◽  
Blood Pressure ◽  
Cardiovascular Risk ◽  
Birth Weight ◽  
Children And Adolescents ◽  
Cardiovascular Risk Factors ◽  
Arterial Blood Pressure ◽  
High Birth Weight ◽  
Arterial Blood

Background/Aims: This study aimed to identify a possible association among high birth weight with overweight/obesity, high arterial blood pressure, dyslipidemia, and insulin resistance in children and adolescents. Methods: This is a cross-sectional study with 719 children and adolescents (6–12 years) stratified according to birth weight (low birth weight [LBW] <2,500 g, adequate birth weight [ABW] 2,500–3,999 g, and high birth weight [HBW] ≥4,000 g). Data collected were anthropometric data, arterial blood pressure levels, lipid profile, and insulin resistance (fasting glucose and insulin, used to calculate homeostatic model assessment-IR). Results: The mean age of schoolchildren was 9.5 ± 2.0 years and 371 (51.6%) were male. LBW and HBW were observed in 79 of 719 (10.9%) and 40 of 719 (55.6%) children/adolescents, respectively. There was no increased risk of overweight (OR 0.9; 95% CI 0.4–2.1; p = 0.964) and obesity (OR 1.4; 95% CI 0.6–3.5; p = 0.588) in HBW group compared to LBW and ABW groups. HBW was not associated with high blood pressure, dyslipidemia, and insulin resistance. The LBW group was independently associated with higher values of systolic (OR 1.07; 95% CI 1.05–1.10; p < 0.01) and diastolic blood pressure (OR 1.04; 95% CI 1.00–1.07; p = 0.044). Conclusion: There was no association between HBW with overweight/obesity and classic cardiovascular risk factors in this group of children/adolescents. Only LBW was related to higher blood pressure levels.

Arterial blood pressure and serum lipids in a population of children and adolescents from Southern Italy: The Calabrian Sierras Community Study (CSCS)

2013 ◽  
Vol 168 (2) ◽  
pp. 1108-1114 ◽  
Author(s):  
Francesco Martino ◽  
Paolo Emilio Puddu ◽  
Giuseppe Pannarale ◽  
Chiara Colantoni ◽  
Cristina Zanoni ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Children And Adolescents ◽  
Arterial Blood Pressure ◽  
Serum Lipids ◽  
Southern Italy ◽  
Community Study ◽  
Arterial Blood

Systemic Haemodynamics in Mild Arterial Hypertension before and after Physical Training

1973 ◽  
Vol 45 (s1) ◽  
pp. 145s-149s ◽  
Author(s):  
R. Sannerstedt ◽  
H. Wasir ◽  
R. Henning ◽  
L. Werkö
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Arterial Hypertension ◽  
Arterial Blood Pressure ◽  
Physical Training ◽  
Blood Pressure Level ◽  
Work Load ◽  
Physical Conditioning ◽  
Arterial Blood ◽  
Before And After

1. Five men with borderline, latent arterial hypertension of the hyperkinetic type were studied haemodynamically at rest and during dynamic exercise before and after a 6-week period of supervised physical training. 2. Tendencies to lower heart rate, cardiac output and arterial blood pressure, both at rest and during a standardized work-load, were observed after the training period, with significant differences between paired observations for the heart rate and mean arterial blood pressure during exercise. The systemic vascular resistance being unchanged, there was a certain trend to an increased widening of the arteriovenous oxygen difference, both at rest and during exercise. 3. The present findings from a small number of subjects indicate that physical conditioning of patients with latent hypertension of the hyperkinetic type contributes to a normalization of their circulation toward a normokinetic one, thereby also normalizing their blood pressure level and achieving a more economic energy expenditure in the cardiovascular system.

scholarly journals INFLUENCE OF SHORT-TERM AIR POLLUTION WITH CARBON MONOXIDE ON THE RISK OF AMBULANCE CALL-OUTS RELATED TO ARTERIAL HYPERTENSION / TRUMPALAIKIS ORO TARŠOS ANGLIES MONOKSIDU POVEIKIS GREITOSIOS MEDICINOS PAGALBOS IŠKVIETIMŲ DĖL ARTERINĖS HIPERTENZIJOS RIZIKA

2015 ◽  
Vol 7 (4) ◽  
pp. 385-391 ◽  
Author(s):  
Agnė Brazienė ◽  
Jonė Venclovienė ◽  
Rūta Babarskienė ◽  
Tautvydė Danilčikaitė
Keyword(s):  
Blood Pressure ◽  
Air Pollution ◽  
Carbon Monoxide ◽  
Arterial Hypertension ◽  
Arterial Blood Pressure ◽  
Air Temperature ◽  
Negative Influence ◽  
Short Term ◽  
Arterial Blood ◽  
Negative Effect

Air pollution by carbon monoxide can be possibly related to the increase in arterial blood pressure and the risk of arterial hypertension. The study was made in Kaunas. The concentration of daily carbon monoxide was estimated according to the data provided by the Department of Environment of Kaunas and environmental monitoring stations of Kaunas city municipality. The study aims to determine a short-term impact of air pollution by carbon monoxide on the number of calls for ambulance due to the risk of arterial hypertension. The following factors were taken into consideration during the study: the time of calling for ambulance, seasons, weekdays and air temperature. Almost half of calls for ambulance (45.1%) due to the increase in arterial blood pressure were recorded in the afternoon (from 0 to 15 calls a day). The number of calls for ambulance due to the increase in arterial blood pressure was the lowest in the warmest time of the year (summer) regardless of the time of the day, and the highest in winter (in the afternoon and evening). The number of calls for ambulance at night due to the increase in arterial blood pressure was significantly higher on Mondays and Tuesdays. The number of calls for ambulance was 14% lower in the afternoon when the air temperature was 10 oC and 13% lower in the evening and at night. The number of calls for ambulance due to the increase in arterial blood pressure can be related to increased concentration of carbon monoxide one day before the call for ambulance (as a result of increased concentration of carbon monoxide by 1 mg/m3, the risk increases by 1.24 times). Increased concentration of carbon monoxide did not have negative influence on the number of calls for ambulance. Negative effect of carbon monoxide was observed when daily carbon concentration exceeded 80th percentile (0.583 mg/m3). Oro tarša anglies monoksidu, tikėtina, susijusi su arterinio kraujo spaudimo padidėjimu bei arterinės hipertenzijos išsivystymo rizika. Tyrimas atliktas Kaune, paros anglies monoksido koncentracija vertinta pagal Kauno regiono aplinkos apsaugos departamento ir miesto savivaldybės ekologinio monitoringo stotyse išmatuotus duomenis. Tyrimo tikslas – nustatyti trumpalaikį oro taršos anglies monoksidu poveikį greitosios medicinos pagalbos iškvietimų dėl arterinės hipertenzijos rizikai, atsižvelgiant į iškvietimo laiką ir kontroliuojant sezoniškumo, savaitės dienos bei oro temperatūros įtaką. Beveik pusė iškvietimų (45,1 %) dėl arterinio kraujo spaudimo padidėjimo buvo registruojami popietinėmis valandomis (nuo 0 iki 15 iškvietimų per parą). Šilčiausiu metų laiku (vasarą) iškvietimų skaičius dėl arterinio kraujospūdžio padidėjimo nepriklausomai nuo paros meto buvo mažiausias, o didžiausias – žiemą (po pietų ir vakare). Nakties metu iškvietimų rizika dėl padidėjusio arterinio kraujo spaudimo buvo žymiai didesnė pirmadieniais ir antradieniais. Iškvietimo parą oro temperatūrai pakilus 10 ºC greitosios medicinos pagalbos iškvietimų rizika buvo 14 % mažesnė popietinėmis valandomis bei 13 % mažesnė vakare ir naktį. Iškvietimų dėl padidėjusio arterinio kraujospūdžio ryte rizika sietina su padidėjusia anglies monoksido koncentracija parą prieš iškvietimą (padidėjus anglies monoksido koncentracijai 1 mg/m3, rizika padidėja 1,24 karto). Padidėjusi anglies monoksido koncentracija neigiamos įtakos iškvietimams neturėjo. Neigiamas anglies monoksido poveikis stebėtas paros koncentracijai viršijus 80 procentilių (0,583 mg/m3).

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