Earthquake is one of the catastrophic natural disasters in the history of mankind which consumed hundreds and thousandsof human lives every year. Attitude of man in handling natural environment make earthquakes inevitable. The study wasdesign to examine the impact of earthquake magnitude on lives loss during earthquakes. Data adopted for study are solelysecondary data which include; journals, textbooks, published and unpublished document. Sampled was derived using purposivesampling techniques, earthquakes that lives were loss during their occurrence characterized with 6.0Mw and above wereselected as sample. Regression analysis, maps QGIS software, tables and graphs were used for data analysis in study. Theresult of the research indicate a fair relation among studied variables. Figure 1 Multiple R=0.073, Figure multiple=0.454and Figure multiple R=0.452. Multiple R determine the nature of relation between study variables, the close the value ofmultiple R is to 1 the strong the relationship. Which means fair relationship exist between earthquake magnitudes and liveloss during 1990-2019 earthquakes. And R2 result Figure 1, 1% of the lives lost during earthquakes 1990-1999 are determineby earthquake magnitude, R2 result in Figure 4 indicated 21% of the lives lost during earthquakes 2000-2009 are determineby earthquake magnitude and R2 result in Figure 6 demonstrate 20% of the lives loss during earthquakes 2010-2019 aredetermine by earthquake magnitudes. Significant F results are Figure 1 significant F =0.613, Figure 4 significant F=0.001 andFigure 6 significant F=0.0004. Two out of the three significant F result indicated that the result of the research is reliablewhile one result indicated that the result is less reliable. However, the result of the research signifies, other factors such aspopulation density of the area where the earthquakes occur, the geological structure of the areas where the earthquake takeplace, the time at which the earthquake occur i.e. night or during daylight and precipitation also trigger earthquakes in a fewkilometer depth influence number lives lost during earthquake.